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Thomas MacCarthy
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Journal Articles

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas

Marién Pascual, María Mena-Varas, Eloy Francisco Robles, Maria-Jose Garcia-Barchino, Carlos Panizo, Sandra Hervas-Stubbs, Diego Alignani, Ainara Sagardoy, Jose Ignacio Martinez-Ferrandis, Karen L. Bunting, Stephen Meier, Xavier Sagaert, Davide Bagnara, Elizabeth Guruceaga, Oscar Blanco, Jon Celay, Alvaro Martínez-Baztan, Noelia Casares, Juan José Lasarte, Thomas MacCarthy, Ari Melnick, Jose Angel Martinez-Climent, Sergio Roa
Journal: Blood
Blood (2019) 133 (22): 2401–2412.
https://doi.org/10.1182/blood.2018889931
Published: 2019
Includes: Supplemental data
Journal Articles

The Correlation of APOBEC Gene Family Member Expression with Worse CLL Patient Outcome Suggests a Role in CLL Mutational Evolution

Charles C Chu, Xiao-Jie Yan, MD PhD, Arvind Dhayalan, Piers E. Patten, BSc, MRCP, MRCPath, PhD, Thomas MacCarthy, PhD, Chaohui Yuan, MS, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L Allen, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2015) 126 (23): 363.
https://doi.org/10.1182/blood.V126.23.363.363
Published: 2015
Journal Articles

IGHV-D-J Ultra-Deep Sequencing Reveals APOBEC and AID Targeted Mutations during Clonal Evolution of CLL in a Xenograft Mouse Model

Charles C. Chu, PhD, Piers E.M. Patten, BSc, MRCP, MRCPath, PhD, Thomas MacCarthy, PhD, Chaohui Yuan, MS, Xiao-Jie Yan, MD PhD, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2014) 124 (21): 300.
https://doi.org/10.1182/blood.V124.21.300.300
Published: 2014
Journal Articles

Evaluation of IGHV Ultra-Deep Sequences for Activation-Induced Deaminase Characteristics in CLL Cells after T Cell Stimulation

Charles C. Chu, PhD, Piers E.M. Patten, MD, PhD, Thomas MacCarthy, PhD, Xiao-Jie Yan, MD PhD, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2013) 122 (21): 2583.
https://doi.org/10.1182/blood.V122.21.2583.2583
Published: 2013
Journal Articles

IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions

Piers E. M. Patten, Charles C. Chu, Emilia Albesiano, Rajendra N. Damle, Xiao-Jie Yan, Dorothy Kim, Lu Zhang, Amanda R. Magli, Jacqueline Barrientos, Jonathan E. Kolitz, Steven L. Allen, Kanti R. Rai, Sergio Roa, Patricia K. Mongini, Thomas MacCarthy, Matthew D. Scharff, Nicholas Chiorazzi
Journal: Blood
Blood (2012) 120 (24): 4802–4811.
https://doi.org/10.1182/blood-2012-08-449744
Published: 2012
Includes: Supplemental data
Journal Articles

CLL Cells Can Diversify, Switch, and Differentiate in Response to Autologous T Cell Stimuli Present in a Murine Adoptive Transfer Model

Piers E.M. Patten, MBBCh, PhD, Shih-Shih Chen, Ph.D., Davide Bagnara, Ph.D., Rita Simone, PhD, Sonia Marsilio, PhD, Xiao-Jie Yan, MD PhD, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Thomas MacCarthy, PhD, Charles C. Chu, PhD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2012) 120 (21): 315.
https://doi.org/10.1182/blood.V120.21.315.315
Published: 2012
Journal Articles

Ultra-Deep Sequencing of De Novo IGHV Mutations in Activated CLL Cells: Evidence for Activation-Induced Deaminase Function.

Piers E.M. Patten, MBBCh, PhD, Thomas MacCarthy, PhD, Xiao-Jie Yan, MD PhD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Jacqueline C. Barrientos, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD, Charles C. Chu, PhD
Journal: Blood
Blood (2012) 120 (21): 2545.
https://doi.org/10.1182/blood.V120.21.2545.2545
Published: 2012