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Issue Archive

Volume 132, Issue 4
July 26 2018
Issue Cover

Table of Contents

EDITORIAL

Introduction to a review series on adolescent and young adult malignant hematology
Jorge Cortes
View Articletitled, Introduction to a review series on adolescent and young adult malignant hematology

BLOOD COMMENTARIES

Lymphoid Neoplasia
A tale of two mantle cell lymphomas
Peter Martin
View Articletitled, A tale of two mantle cell lymphomas
THROMBOSIS AND HEMOSTASIS
Hypoxia and thrombosis
Josef T. Prchal
View Articletitled, Hypoxia and thrombosis

REVIEW SERIES

Acute lymphoblastic leukemia in adolescent and young adults: treat as adults or as children?
Clinical Trials & Observations
Nicolas Boissel,André Baruchel
View Articletitled, Acute lymphoblastic leukemia in adolescent and young adults: treat as adults or as children?
Treatment strategies for adolescent and young adult patients with acute myeloid leukemia
Kristen O’Dwyer,David R. Freyer,John T. Horan
View Articletitled, Treatment strategies for adolescent and young adult patients with acute myeloid leukemia
Management of aggressive B-cell NHLs in the AYA population: an adult vs pediatric perspective
Clinical Trials & Observations
Kieron Dunleavy,Thomas G. Gross
View Articletitled, Management of aggressive B-cell NHLs in the AYA population: an adult vs pediatric perspective
The management of Hodgkin lymphoma in adolescents and young adults: burden of disease or burden of choice?
Clinical Trials & Observations
Jamie E. Flerlage,Monika L. Metzger,Nickhill Bhakta
View Articletitled, The management of Hodgkin lymphoma in adolescents and young adults: burden of disease or burden of choice?
Psychosocial challenges and health-related quality of life of adolescents and young adults with hematologic malignancies
Clinical Trials & Observations
Olga Husson,Peter C. Huijgens,Winette T. A. van der Graaf
View Articletitled, Psychosocial challenges and health-related quality of life of adolescents and young adults with hematologic malignancies

CLINICAL TRIALS AND OBSERVATIONS

Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial
Clinical Trials & Observations
Jorge E. Cortes,Dong-Wook Kim,Javier Pinilla-Ibarz,Philipp D. le Coutre,Ronald Paquette,Charles Chuah,Franck E. Nicolini,Jane F. Apperley,H. Jean Khoury,Moshe Talpaz,Daniel J. DeAngelo,Elisabetta Abruzzese,Delphine Rea,Michele Baccarani,Martin C. Müller,Carlo Gambacorti-Passerini,Stephanie Lustgarten,Victor M. Rivera,Frank G. Haluska,François Guilhot,Michael W. Deininger,Andreas Hochhaus,Timothy P. Hughes,Neil P. Shah,Hagop M. Kantarjian
View Articletitled, Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial
Supplemental data
Risk-adapted treatment of acute promyelocytic leukemia: results from the International Consortium for Childhood APL
Clinical Trials & Observations
Anna Maria Testi,Andrea Pession,Daniela Diverio,David Grimwade,Brenda Gibson,Amilcar Cardoso de Azevedo,Lorena Moran,Guy Leverger,Sarah Elitzur,Henrik Hasle,Jutte van der Werff ten Bosch,Owen Smith,Marisa De Rosa,Alfonso Piciocchi,Francesco Lo Coco,Robin Foà,Franco Locatelli,Gertjan J. L. Kaspers
View Articletitled, Risk-adapted treatment of acute promyelocytic leukemia: results from the International Consortium for Childhood APL
Supplemental data

LYMPHOID NEOPLASIA

A gene signature that distinguishes conventional and leukemic nonnodal mantle cell lymphoma helps predict outcome
Guillem Clot,Pedro Jares,Eva Giné,Alba Navarro,Cristina Royo,Magda Pinyol,David Martín-Garcia,Santiago Demajo,Blanca Espinet,Antonio Salar,Ana Ferrer,Ana Muntañola,Marta Aymerich,Hilka Rauert-Wunderlich,Elaine S. Jaffe,Joseph M. Connors,Randy D. Gascoyne,Jan Delabie,Armando López-Guillermo,German Ott,George W. Wright,Louis M. Staudt,Andreas Rosenwald,David W. Scott,Lisa M. Rimsza,Sílvia Beà,Elías Campo
View Articletitled, A gene signature that distinguishes conventional and leukemic nonnodal mantle cell lymphoma helps predict outcome
Supplemental data

MYELOID NEOPLASIA

USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism
Johanna Melo-Cardenas,Yuanming Xu,Juncheng Wei,Can Tan,Sinyi Kong,Beixue Gao,Elena Montauti,Gina Kirsammer,Jonathan D. Licht,Jindan Yu,Peng Ji,John D. Crispino,Deyu Fang
View Articletitled, USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism
Supplemental data

TRANSPLANTATION

Bim regulates the survival and suppressive capability of CD8+ FOXP3+ regulatory T cells during murine GVHD
Kimberle Agle,Benjamin G. Vincent,Clint Piper,Ludovic Belle,Vivian Zhou,Warren Shlomchik,Jonathan S. Serody,William R. Drobyski
View Articletitled, Bim regulates the survival and suppressive capability of CD8<sup>+</sup> FOXP3<sup>+</sup> regulatory T cells during murine GVHD
Supplemental data

LETTERS TO BLOOD

Normalizing hepcidin predicts TMPRSS6 mutation status in patients with chronic iron deficiency
Matthew M. Heeney,Dongjing Guo,Luigia De Falco,Dean R. Campagna,Gordana Olbina,Paige P.-C. Kao,Klaus Schmitz-Abe,Fedik Rahimov,Patrick Gutschow,Keith Westerman,Vaughn Ostland,Tracy Jackson,Robert J. Klaassen,Kyriacos Markianos,Karin E. Finberg,Achille Iolascon,Mark Westerman,Wendy B. London,Mark D. Fleming
View Articletitled, Normalizing hepcidin predicts <em>TMPRSS6</em> mutation status in patients with chronic iron deficiency
Supplemental data
Hypoxia downregulates protein S expression
Vijaya S. Pilli,Arani Datta,Sadaf Afreen,Donna Catalano,Gyongyi Szabo,Rinku Majumder
View Articletitled, Hypoxia downregulates protein S expression
Supplemental data

BLOOD WORK

NUT midline carcinoma with leukemic presentation mimicking CD34-positive acute leukemia
Weijie Li,Katherine Chastain
View Articletitled, NUT midline carcinoma with leukemic presentation mimicking CD34-positive acute leukemia
Cuplike nuclear morphology in pediatric B-cell acute lymphoblastic leukemia
Aida Ibricevic Richardson,Weijie Li
View Articletitled, Cuplike nuclear morphology in pediatric B-cell acute lymphoblastic leukemia

ERRATA

Pro B, Advani R, Brice P, et al. Five-year results of brentuximab vedotin in patients with relapsed or refractory systemic anaplastic large cell lymphoma. Blood. 2017;130(25):2709-2717.
View Articletitled, Pro B, Advani R, Brice P, et al. Five-year results of brentuximab vedotin in patients with relapsed or refractory systemic anaplastic large cell lymphoma. <em>Blood.</em> 2017;130(25):2709-2717.
Zhao Z, Sun Q, Sokoll LJ, et al. Eltrombopag mobilizes iron in patients with aplastic anemia. Blood. 2018;131(21):2399-2402.
View Articletitled, Zhao Z, Sun Q, Sokoll LJ, et al. Eltrombopag mobilizes iron in patients with aplastic anemia. <em>Blood.</em> 2018;131(21):2399-2402.
Sugimoto MA, Ribeiro ALC, Costa BRC, et al. Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1. Blood. 2017;129(21):2896-2907.
View Articletitled, Sugimoto MA, Ribeiro ALC, Costa BRC, et al. Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1. <em>Blood</em>. 2017;129(21):2896-2907.
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Data mining for second malignancies after CAR-T
Silva A, Almeida ARM, Cachucho A, et al. Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma. Blood. 2021;138(12):1040-1052.
MRD and EFS in pediatric T-lymphoblastic lymphoma
Outcomes of younger patients with mantle-cell lymphoma experiencing late relapse (>24 months): the LATE-POD study
Mutational profile of previously treated chronic lymphocytic leukemia patients progressing on acalabrutinib or ibrutinib

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