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Issue Archive

Volume 132, Issue 3
July 19 2018
Issue Cover

Table of Contents

BLOOD COMMENTARIES

CLINICAL TRIALS AND OBSERVATIONS
The cells are ambiguous, not the message
Clinical Trials & Observations
Pierre S. Rohrlich
View Articletitled, The cells are ambiguous, not the message
Lymphoid Neoplasia
PI3K inhibitors and the search for the Holy Grail
Ian W. Flinn
View Articletitled, PI3K inhibitors and the search for the Holy Grail
MYELOID NEOPLASIA
HSP90 inhibition without heat shock response
John C. Byrd
View Articletitled, HSP90 inhibition without heat shock response
TRANSFUSION MEDICINE
XG blood group puzzle solved: what’s next?
Peter A. Zimmerman
View Articletitled, XG blood group puzzle solved: what’s next?

REVIEW ARTICLE

Allogeneic hematopoietic stem cell transplantation for T-cell lymphomas
Norbert Schmitz,Georg Lenz,Matthias Stelljes
View Articletitled, Allogeneic hematopoietic stem cell transplantation for T-cell lymphomas

HOW I TREAT

How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa
Clinical Trials & Observations
Satish Gopal,Thomas G. Gross
View Articletitled, How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa

CLINICAL TRIALS AND OBSERVATIONS

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia
CME Clinical Trials & Observations
Ondrej Hrusak,Valerie de Haas,Jitka Stancikova,Barbora Vakrmanova,Iveta Janotova,Ester Mejstrikova,Vaclav Capek,Jan Trka,Marketa Zaliova,Ales Luks,Kirsten Bleckmann,Anja Möricke,Julie Irving,Benigna Konatkowska,Thomas B. Alexander,Hiroto Inaba,Kjeld Schmiegelow,Simone Stokley,Zuzana Zemanova,Anthony V. Moorman,Jorge Gabriel Rossi,Maria Sara Felice,Luciano Dalla-Pozza,Jessa Morales,Michael Dworzak,Barbara Buldini,Giuseppe Basso,Myriam Campbell,Maria Elena Cabrera,Neda Marinov,Sarah Elitzur,Shai Izraeli,Drorit Luria,Tamar Feuerstein,Alexandra Kolenova,Peter Svec,Olena Kreminska,Karen R. Rabin,Sophia Polychronopoulou,Elaine da Costa,Hanne Vibeke Marquart,Antonis Kattamis,Richard Ratei,Dirk Reinhardt,John K. Choi,Martin Schrappe,Jan Stary
View Articletitled, International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Lineage restriction analyses in CHIP indicate myeloid bias for TET2 and multipotent stem cell origin for DNMT3A
Brief Report
Manuel Buscarlet,Sylvie Provost,Yassamin Feroz Zada,Vincent Bourgoin,Luigina Mollica,Marie-Pierre Dubé,Lambert Busque
View Articletitled, Lineage restriction analyses in CHIP indicate myeloid bias for <em>TET2</em> and multipotent stem cell origin for <em>DNMT3A</em>

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Hypomorphic Rag1 mutations alter the preimmune repertoire at early stages of lymphoid development
L. M. Ott de Bruin,M. Bosticardo,A. Barbieri,S. G. Lin,J. H. Rowe,P. L. Poliani,K. Ching,D. Eriksson,N. Landegren,O. Kämpe,J. P. Manis,L. D. Notarangelo
View Articletitled, Hypomorphic <em>Rag1</em> mutations alter the preimmune repertoire at early stages of lymphoid development
Supplemental data

LYMPHOID NEOPLASIA

Phase 1 study of the PI3Kδ inhibitor INCB040093 ± JAK1 inhibitor itacitinib in relapsed/refractory B-cell lymphoma
Clinical Trials & Observations
Tycel J. Phillips,Andres Forero-Torres,Taimur Sher,Catherine S. Diefenbach,Patrick Johnston,Moshe Talpaz,Jennifer Pulini,Li Zhou,Peggy Scherle,Xuejun Chen,Paul M. Barr
View Articletitled, Phase 1 study of the PI3Kδ inhibitor INCB040093 ± JAK1 inhibitor itacitinib in relapsed/refractory B-cell lymphoma
Supplemental data

MYELOID NEOPLASIA

Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response
Sanil Bhatia,Daniela Diedrich,Benedikt Frieg,Heinz Ahlert,Stefan Stein,Bertan Bopp,Franziska Lang,Tao Zang,Tobias Kröger,Thomas Ernst,Gesine Kögler,Andreas Krieg,Steffen Lüdeke,Hana Kunkel,Ana J. Rodrigues Moita,Matthias U. Kassack,Viktoria Marquardt,Friederike V. Opitz,Marina Oldenburg,Marc Remke,Florian Babor,Manuel Grez,Andreas Hochhaus,Arndt Borkhardt,Georg Groth,Luitgard Nagel-Steger,Joachim Jose,Thomas Kurz,Holger Gohlke,Finn K. Hansen,Julia Hauer
View Articletitled, Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells
Yankai Zhang,Alireza Paikari,Pavel Sumazin,Carly C. Ginter Summarell,Jacy R. Crosby,Eric Boerwinkle,Mitchell J. Weiss,Vivien A. Sheehan
View Articletitled, Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells
Supplemental data

TRANSFUSION MEDICINE

Disruption of a GATA1-binding motif upstream of XG/PBDX abolishes Xga expression and resolves the Xg blood group system
Brief Report
Mattias Möller,Yan Quan Lee,Karina Vidovic,Sven Kjellström,Linda Björkman,Jill R. Storry,Martin L. Olsson
View Articletitled, Disruption of a GATA1-binding motif upstream of <em>XG</em>/<em>PBDX</em> abolishes Xg<sup>a</sup> expression and resolves the Xg blood group system
Supplemental data

LETTER TO BLOOD

Benefit of brentuximab over bleomycin in first-line treatment of advanced-stage Hodgkin lymphoma has not been proven
Clinical Trials & Observations
Hugo J. A. Adams,Thomas C. Kwee
View Articletitled, Benefit of brentuximab over bleomycin in first-line treatment of advanced-stage Hodgkin lymphoma has not been proven

BLOOD WORK

Aberrant T-cell antigen expression in a plasma cell neoplasm
Smita Patel,Bachir Alobeid
View Articletitled, Aberrant T-cell antigen expression in a plasma cell neoplasm

ERRATUM

Table of contents. Blood. 2018;131(18):ix-x.
View Articletitled, Table of contents. <em>Blood.</em> 2018;131(18):ix-x.

CONTINUING MEDICAL EDUCATION (CME) QUESTIONS

Ambiguous lineage leukemia treatment
CME
View Articletitled, Ambiguous lineage leukemia treatment
All Issues

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