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Pavel Sumazin
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Journal Articles

Abundance of Relapse-Predictive Cells Can be Estimated at Diagnosis and Is Strongly Associated with Outcome in Pediatric AML

Mohammad Javad Najaf Panah, Alexandra McLean Stevens, Michael Krueger, Max P Rochette, Sohani K Sandhu, Lana E Kim, Joanna S. Yi, Tsz-Kwong Man, Michele S. Redell, Pavel Sumazin
Journal: Blood
Blood (2024) 144 (Supplement 1): 63.
https://doi.org/10.1182/blood-2024-206142
Published: 2024
Journal Articles

A Novel Transgenic Mouse Model of Down Syndrome Acute Lymphoblastic Leukemia Identifies Targetable Vulnerabilities

Jacob J. Junco, Raushan Rashid, Maci Terrell, Michelle Alozie, Max Rochette, Barry Zorman, Pavel Sumazin, Lauren Rowland, Gino Dettorre, Reid T. Powell, Clifford C. Stephan, Peter J. Davies, Margie M. Moczygemba, Jun J. Yang, Karen R. Rabin
Journal: Blood
Blood (2023) 142 (Supplement 1): 2981.
https://doi.org/10.1182/blood-2023-187324
Published: 2023
Journal Articles

Single Cell Transcriptome Comparisons of Diagnosis-Relapse Pairs Uncover Programs Associated with Chemoresistance in Pediatric AML

Mohammad Javad Najaf Panah, Tsz-Kwong Man, Michael Krueger, Pavel Sumazin, Michele S. Redell
Journal: Blood
Blood (2023) 142 (Supplement 1): 1574.
https://doi.org/10.1182/blood-2023-184926
Published: 2023
Journal Articles

Cite-Seq Reveals Distinct Patterns and Potential Mechanisms of Relapse in Pediatric AML

Tsz-Kwong Man, Mohammad Javad Najaf Panah, Jessica L. Elswood, Pavel Sumazin, Michele S. Redell
Journal: Blood
Blood (2021) 138 (Supplement 1): 3458.
https://doi.org/10.1182/blood-2021-152646
Published: 2021
Journal Articles

The Krüppel-like Factor 4 Sustains a Leukemic Gene Expression Profile in MLL-AF9-Driven Acute Myeloid Leukemia

Andrew Lewis, Cory Seth Bridges, David Moorshead, Wa Du, Barry Zorman, Pavel Sumazin, Monica Puppi, H. Daniel Lacorazza
Journal: Blood
Blood (2021) 138 (Supplement 1): 1143.
https://doi.org/10.1182/blood-2021-151613
Published: 2021
Journal Articles

Precision Medicine for Sickle Cell Disease through Whole Genome Sequencing

Evadnie Rampersaud, PhD, Lance E. Palmer, PhD, Jane S. Hankins, MD MS, Vivien A Sheehan, MD PhD, Wenjian Bi, PhD, Heather Mulder, BS, Guolian Kang, PhD, Jeremie H. Estepp, MD, Shuoguo Wang, PhD, Andrew Thrasher, PhD, Martha Villavicencio, PhD, Jason R Hodges, PhD MA, Wenan Chen, PhD, Ti-Cheng Chang, PhD, Yong Cheng, PhD, Michael Rusch, BS, Yadav Sapkota, PhD, Akshay Sharma, MBBS, Pavel Sumazin, PhD, Xing Tang, PhD, Amanda M. Brandow, DO, MS, Shawn Levy, Nidal Boulos, PhD, Celeste Rosencrance, BS, Donald Yergeau, PhD, Jeffrey Lebensburger, DO, MSPH, Winfred Wang, MD, Yutaka Yasui, PhD, John Easton, PhD, Michael R. DeBaun, MD, James R. Downing, MD, Jinghui Zhang, Gang Wu, PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3641.
https://doi.org/10.1182/blood-2018-99-117606
Published: 2018
Journal Articles

Expression Differences Distinguish Pediatric Acute and Chronic ITP Using RNA Sequencing

Taylor Kim, MD, Hyunjae Kim, PhD, Pavel Sumazin, PhD, Amanda Bell Grimes, MD, Katherine Jenson, BA, Rachael F. Grace, MD, Michele P. Lambert, MD, Jonathan Flanagan, PhD, Jenny M. Despotovic, DO, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 127.
https://doi.org/10.1182/blood-2018-99-118581
Published: 2018
Journal Articles

Insulin-like Growth Factor Binding Protein-3 (IGFBP3) Induces Fetal Hemoglobin in Hematopoietic Stem and Progenitor Cells from Patients with Sickle Cell Anemia

Alireza Paikari, MD, Tian Mi, PhD, Yankai Zhang, PhD, Evadnie Rampersaud, PhD, Guolian Kang, PhD, Gang Wu, PhD, Jane S. Hankins, MD MS, Jeremie H. Estepp, MD, Pavel Sumazin, PhD, Mitchell J. Weiss, MD PhD, Vivien A Sheehan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 722.
https://doi.org/10.1182/blood-2018-99-115383
Published: 2018
Journal Articles

Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells

Yankai Zhang, Alireza Paikari, Pavel Sumazin, Carly C. Ginter Summarell, Jacy R. Crosby, Eric Boerwinkle, Mitchell J. Weiss, Vivien A. Sheehan
Journal: Blood
Blood (2018) 132 (3): 321–333.
https://doi.org/10.1182/blood-2017-11-814335
Published: 2018
Includes: Supplemental data
Journal Articles

Piceatannol Induces Fetal Hemoglobin in Erythroid Progenitor Cells from Patients with Sickle Cell Disease

Yankai Zhang, PhD, Alicia Chang, MD, Pavel Sumazin, PhD, Vivien Sheehan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2221.
https://doi.org/10.1182/blood.V130.Suppl_1.2221.2221
Published: 2017
Journal Articles

Metformin Induction of Fetal Hemoglobin

Yankai Zhang, PhD, Alireza Paikari, MD, Pavel Sumazin, PhD, Alex George, MD, PhD, Bogdan Dinu, MD, Carly Summarell, MS, Mitchell J Weiss, MD PhD, Vivien Sheehan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 359.
https://doi.org/10.1182/blood.V130.Suppl_1.359.359
Published: 2017
Journal Articles

Interleukin-6 Levels Predict Relapse Free Survival in Pediatric AML and Suggest a Mechanism of Chemotherapy Resistance

Alexandra M. Stevens, MD, Jennifer K Mehl, MD, Pavel Sumazin, PhD, Michele S. Redell, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1724.
https://doi.org/10.1182/blood.V128.22.1724.1724
Published: 2016
Journal Articles

Metformin Induces FOXO3-Dependent Fetal Hemoglobin Production in Primary Erythroid Cells

Yankai Zhang, PhD, Mitch Weiss, MD PhD, Pavel Sumazin, PhD, Vivien A. Sheehan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 322.
https://doi.org/10.1182/blood.V128.22.322.322
Published: 2016
Journal Articles

MiR-28 Silencing In Germinal Center-Derived Lymphomas

Christof Schneider, MD, Roy L Maute, Pavel Sumazin, PhD, Manisha Brahmachary, PhD, Manu Setty, Laura Pasqualucci, MD, Angelo Rosolen, MD, Christina Leslie, PhD, Katia Basso, PhD, Riccardo Dalla-Favera, MD
Journal: Blood
Blood (2010) 116 (21): 703.
https://doi.org/10.1182/blood.V116.21.703.703
Published: 2010
Journal Articles

Identification of NOTCH1-Controlled Transcriptional Programs In Human T-Cell Development

Giusy Della Gatta, PhD, Alberto Ambesi Impiombato, PhD, Teresa Palomero, PhD, Valeria Tosello, PhD, Pavel Sumazin, PhD, Andrea Califano, PhD, Adolfo Ferrando, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2495.
https://doi.org/10.1182/blood.V116.21.2495.2495
Published: 2010
Journal Articles

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells

Katia Basso, Masumichi Saito, Pavel Sumazin, Adam A. Margolin, Kai Wang, Wei-Keat Lim, Yukiko Kitagawa, Christof Schneider, Mariano J. Alvarez, Andrea Califano, Riccardo Dalla-Favera
Journal: Blood
Blood (2010) 115 (5): 975–984.
https://doi.org/10.1182/blood-2009-06-227017
Published: 2010
Includes: Supplemental data
Journal Articles

Integrated Biochemical and Computational Approach Identifies BCL6 Direct Target Genes Controlling Multiple Pathways in Normal Germinal-Center B Cells

Masumichi Saito, PhD, Katia Basso, PhD, Pavel Sumazin, PhD, Adam A Margolin, PhD, Kai Wang, PhD, Wei-Keat Lim, Andrea Califano, PhD, Riccardo Dalla-Favera, MD
Journal: Blood
Blood (2008) 112 (11): 2434.
https://doi.org/10.1182/blood.V112.11.2434.2434
Published: 2008