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Human CTL-based functional analysis shows the reliability of a munc13-4 protein expression assay for FHL3 diagnosis
High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology
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Table of Contents
BLOOD COMMENTARIES
BLOOD SPOTLIGHT
REVIEW ARTICLE
CLINICAL TRIALS AND OBSERVATIONS
Human CTL-based functional analysis shows the reliability of a munc13-4 protein expression assay for FHL3 diagnosis
Clinical Trials & Observations
Hirofumi Shibata,Takahiro Yasumi,Saeko Shimodera,Eitaro Hiejima,Kazushi Izawa,Tomoki Kawai,Ryutaro Shirakawa,Taizo Wada,Ryuta Nishikomori,Hisanori Horiuchi,Osamu Ohara,Eiichi Ishii,Toshio Heike
HEMATOPOIESIS AND STEM CELLS
LYMPHOID NEOPLASIA
Somatic IL4R mutations in primary mediastinal large B-cell lymphoma lead to constitutive JAK-STAT signaling activation
Elena Viganò,Jay Gunawardana,Anja Mottok,Tessa Van Tol,Katina Mak,Fong Chun Chan,Lauren Chong,Elizabeth Chavez,Bruce Woolcock,Katsuyoshi Takata,David Twa,Hennady P. Shulha,Adèle Telenius,Olga Kutovaya,Stacy S. Hung,Shannon Healy,Susana Ben-Neriah,Karen Leroy,Philippe Gaulard,Arjan Diepstra,Robert Kridel,Kerry J. Savage,Lisa Rimsza,Randy Gascoyne,Christian Steidl
BTKCys481Ser drives ibrutinib resistance via ERK1/2 and protects BTKwild-type MYD88-mutated cells by a paracrine mechanism
Jiaji G. Chen,Xia Liu,Manit Munshi,Lian Xu,Nicholas Tsakmaklis,Maria G. Demos,Amanda Kofides,Maria Luisa Guerrera,Gloria G. Chan,Christopher J. Patterson,Kirsten Meid,Joshua Gustine,Toni Dubeau,Patricia Severns,Jorge J. Castillo,Zachary R. Hunter,Jinhua Wang,Sara J. Buhrlage,Nathanael S. Gray,Steven P. Treon,Guang Yang
High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology
Brief Report
David W. Scott,Rebecca L. King,Annette M. Staiger,Susana Ben-Neriah,Aixiang Jiang,Heike Horn,Anja Mottok,Pedro Farinha,Graham W. Slack,Daisuke Ennishi,Norbert Schmitz,Michael Pfreundschuh,Grzegorz S. Nowakowski,Brad S. Kahl,Joseph M. Connors,Randy D. Gascoyne,German Ott,William R. Macon,Andreas Rosenwald
MYELOID NEOPLASIA
TRANSPLANTATION
Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease
Shuichiro Takahashi,Daigo Hashimoto,Eiko Hayase,Reiki Ogasawara,Hiroyuki Ohigashi,Takahide Ara,Emi Yokoyama,Ko Ebata,Satomi Matsuoka,Geoffrey R. Hill,Junichi Sugita,Masahiro Onozawa,Takanori Teshima
LETTER TO BLOOD
High prevalence of MYD88 and CD79B mutations in intravascular large B-cell lymphoma
Anne M. R. Schrader,Patty M. Jansen,Rein Willemze,Maarten H. Vermeer,Anne-Marie Cleton-Jansen,Sebastiaan F. Somers,Hendrik Veelken,Ronald van Eijk,Willem Kraan,Marie José Kersten,Michiel van den Brand,Wendy B. C. Stevens,Daphne de Jong,Myrurgia Abdul Hamid,Bea C. Tanis,Eduardus F. M. Posthuma,Marcel Nijland,Arjan Diepstra,Steven T. Pals,Arjen H. G. Cleven,Joost S. P. Vermaat
BLOOD WORK
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Cover Image
Cover Image
Topical ruxolitinib protects hair follicle stem cells expressing both cytokeratin 15 (red) and Lgr5+ (green) at the base of hair follicles against graft-versus-host disease after experimental allogeneic hematopoietic stem cell transplantation. See the article by Takahashi et al on page 2074.
The cover caption has an Erratum 132(3):342
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