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Issue Archive

Volume 131, Issue 18
May 3 2018
Issue Cover

Table of Contents

BLOOD COMMENTARIES

Lymphoid Neoplasia
New pieces in the BTKi resistance puzzle
Jan A. Burger
View Articletitled, New pieces in the BTKi resistance puzzle
Lymphoid Neoplasia
Double-hit DLBCL: should we limit FISH testing?
Christiane Copie-Bergman
View Articletitled, Double-hit DLBCL: should we limit FISH testing?
MYELOID NEOPLASIA
JAK2 and JMJD1C activate NFE2 in MPNs
John D. Crispino
View Articletitled, JAK2 and JMJD1C activate NFE2 in MPNs

BLOOD SPOTLIGHT

Coagulopathy induced by traumatic brain injury: systemic manifestation of a localized injury
Jianning Zhang,Fangyi Zhang,Jing-fei Dong
View Articletitled, Coagulopathy induced by traumatic brain injury: systemic manifestation of a localized injury

REVIEW ARTICLE

The MYC oncogene is a global regulator of the immune response
Stephanie C. Casey,Virginie Baylot,Dean W. Felsher
View Articletitled, The MYC oncogene is a global regulator of the immune response

CLINICAL TRIALS AND OBSERVATIONS

Human CTL-based functional analysis shows the reliability of a munc13-4 protein expression assay for FHL3 diagnosis
Clinical Trials & Observations
Hirofumi Shibata,Takahiro Yasumi,Saeko Shimodera,Eitaro Hiejima,Kazushi Izawa,Tomoki Kawai,Ryutaro Shirakawa,Taizo Wada,Ryuta Nishikomori,Hisanori Horiuchi,Osamu Ohara,Eiichi Ishii,Toshio Heike
View Articletitled, Human CTL-based functional analysis shows the reliability of a munc13-4 protein expression assay for FHL3 diagnosis
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors
Yohei Kawano,Georg Petkau,Christina Stehle,Pawel Durek,Gitta Anne Heinz,Kousuke Tanimoto,Hajime Karasuyama,Mir-Farzin Mashreghi,Chiara Romagnani,Fritz Melchers
View Articletitled, Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors
Supplemental data

LYMPHOID NEOPLASIA

Somatic IL4R mutations in primary mediastinal large B-cell lymphoma lead to constitutive JAK-STAT signaling activation
Elena Viganò,Jay Gunawardana,Anja Mottok,Tessa Van Tol,Katina Mak,Fong Chun Chan,Lauren Chong,Elizabeth Chavez,Bruce Woolcock,Katsuyoshi Takata,David Twa,Hennady P. Shulha,Adèle Telenius,Olga Kutovaya,Stacy S. Hung,Shannon Healy,Susana Ben-Neriah,Karen Leroy,Philippe Gaulard,Arjan Diepstra,Robert Kridel,Kerry J. Savage,Lisa Rimsza,Randy Gascoyne,Christian Steidl
View Articletitled, Somatic IL4R mutations in primary mediastinal large B-cell lymphoma lead to constitutive JAK-STAT signaling activation
Supplemental data
BTKCys481Ser drives ibrutinib resistance via ERK1/2 and protects BTKwild-type MYD88-mutated cells by a paracrine mechanism
Jiaji G. Chen,Xia Liu,Manit Munshi,Lian Xu,Nicholas Tsakmaklis,Maria G. Demos,Amanda Kofides,Maria Luisa Guerrera,Gloria G. Chan,Christopher J. Patterson,Kirsten Meid,Joshua Gustine,Toni Dubeau,Patricia Severns,Jorge J. Castillo,Zachary R. Hunter,Jinhua Wang,Sara J. Buhrlage,Nathanael S. Gray,Steven P. Treon,Guang Yang
View Articletitled, BTK<sup>Cys481Ser</sup> drives ibrutinib resistance via ERK1/2 and protects BTK<sup>wild-type</sup> MYD88-mutated cells by a paracrine mechanism
Supplemental data
High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology
Brief Report
David W. Scott,Rebecca L. King,Annette M. Staiger,Susana Ben-Neriah,Aixiang Jiang,Heike Horn,Anja Mottok,Pedro Farinha,Graham W. Slack,Daisuke Ennishi,Norbert Schmitz,Michael Pfreundschuh,Grzegorz S. Nowakowski,Brad S. Kahl,Joseph M. Connors,Randy D. Gascoyne,German Ott,William R. Macon,Andreas Rosenwald
View Articletitled, High-grade B-cell lymphoma with <em>MYC</em> and <em>BCL2</em> and/or <em>BCL6</em> rearrangements with diffuse large B-cell lymphoma morphology
Supplemental data

MYELOID NEOPLASIA

Epigenetic regulation of NFE2 overexpression in myeloproliferative neoplasms
Jan C. Peeken,Jonas S. Jutzi,Julius Wehrle,Christoph Koellerer,Hans F. Staehle,Heiko Becker,Elias Schoenwandt,Thalia S. Seeger,Daniel H. Schanne,Monika Gothwal,Christopher J. Ott,Albert Gründer,Heike L. Pahl
View Articletitled, Epigenetic regulation of NFE2 overexpression in myeloproliferative neoplasms
Supplemental data

TRANSPLANTATION

Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease
Shuichiro Takahashi,Daigo Hashimoto,Eiko Hayase,Reiki Ogasawara,Hiroyuki Ohigashi,Takahide Ara,Emi Yokoyama,Ko Ebata,Satomi Matsuoka,Geoffrey R. Hill,Junichi Sugita,Masahiro Onozawa,Takanori Teshima
View Articletitled, Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease
Supplemental data

LETTER TO BLOOD

High prevalence of MYD88 and CD79B mutations in intravascular large B-cell lymphoma
Anne M. R. Schrader,Patty M. Jansen,Rein Willemze,Maarten H. Vermeer,Anne-Marie Cleton-Jansen,Sebastiaan F. Somers,Hendrik Veelken,Ronald van Eijk,Willem Kraan,Marie José Kersten,Michiel van den Brand,Wendy B. C. Stevens,Daphne de Jong,Myrurgia Abdul Hamid,Bea C. Tanis,Eduardus F. M. Posthuma,Marcel Nijland,Arjan Diepstra,Steven T. Pals,Arjen H. G. Cleven,Joost S. P. Vermaat
View Articletitled, High prevalence of <em>MYD88</em> and <em>CD79B</em> mutations in intravascular large B-cell lymphoma
Supplemental data

BLOOD WORK

Diffuse large B-cell lymphoma with strong aberrant expression of CD31
Shaomin Hu,Yanhua Wang
View Articletitled, Diffuse large B-cell lymphoma with strong aberrant expression of CD31
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Cardiac complete response in AL amyloidosis has similar survival to matched general population
Randomized Bendamustine-Rituximab(R) + Bortezomib Induction and R + Lenalidomide Maintenance for Mantle Cell Lymphoma
Heme induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice
Interleukin-1 mediated hyperinflammation in XIAP-deficiency is associated with defective autophagy.
NOVEL THERAPEUTIC APPROACHES IN THALASSEMIAS, SICKLE CELL DISEASE AND OTHER RED CELL DISORDERS

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