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Genomic architecture and treatment outcome in pediatric acute myeloid leukemia: a Children’s Oncology Group report
PD-1 blockade with nivolumab in relapsed/refractory primary central nervous system and testicular lymphoma
Molecular convergence in ex vivo models of Diamond-Blackfan anemia
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Table of Contents
INSIDE BLOOD COMMENTARIES
PLENARY PAPER
CLINICAL TRIALS AND OBSERVATIONS
Genomic architecture and treatment outcome in pediatric acute myeloid leukemia: a Children’s Oncology Group report
Clinical Trials & Observations
Marijana Vujkovic,Edward F. Attiyeh,Rhonda E. Ries,Elizabeth K. Goodman,Yang Ding,Marko Kavcic,Todd A. Alonzo,Yi-Cheng Wang,Robert B. Gerbing,Lillian Sung,Betsy Hirsch,Susana Raimondi,Alan S. Gamis,Soheil Meshinchi,Richard Aplenc
PERSPECTIVE
CLINICAL TRIALS AND OBSERVATIONS
PD-1 blockade with nivolumab in relapsed/refractory primary central nervous system and testicular lymphoma
Clinical Trials & Observations
Brief Report
Lakshmi Nayak,Fabio M. Iwamoto,Ann LaCasce,Srinivasan Mukundan,Margaretha G. M. Roemer,Bjoern Chapuy,Philippe Armand,Scott J. Rodig,Margaret A. Shipp
MYELOID NEOPLASIA
miR-155 promotes FLT3-ITD–induced myeloproliferative disease through inhibition of the interferon response
Jared A. Wallace,Dominique A. Kagele,Anna M. Eiring,Carissa N. Kim,Ruozhen Hu,Marah C. Runtsch,Margaret Alexander,Thomas B. Huffaker,Soh-Hyun Lee,Ami B. Patel,Timothy L. Mosbruger,Warren P. Voth,Dinesh S. Rao,Rodney R. Miles,June L. Round,Michael W. Deininger,Ryan M. O’Connell
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
Reduced PU.1 expression underlies aberrant neutrophil maturation and function in β-thalassemia mice and patients
Panjaree Siwaponanan,Jurre Ynze Siegers,Razi Ghazali,Thian Ng,Bradley McColl,Garrett Zhen-Wei Ng,Philip Sutton,Nancy Wang,Isabelle Ooi,Chayada Thiengtavor,Suthat Fucharoen,Pornthip Chaichompoo,Saovaros Svasti,Odilia Wijburg,Jim Vadolas
RED CELLS, IRON, AND ERYTHROPOIESIS
Molecular convergence in ex vivo models of Diamond-Blackfan anemia
Clinical Trials & Observations
Kelly A. O'Brien,Jason E. Farrar,Adrianna Vlachos,Stacie M. Anderson,Crystiana A. Tsujiura,Jens Lichtenberg,Lionel Blanc,Eva Atsidaftos,Abdel Elkahloun,Xiuli An,Steven R. Ellis,Jeffrey M. Lipton,David M. Bodine
TRANSPLANTATION
LETTERS TO BLOOD
Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA
Itaru Kato,Yoko Nishinaka,Masahiro Nakamura,Ayse U. Akarca,Akira Niwa,Hiroki Ozawa,Kenichi Yoshida,Makiko Mori,Dapeng Wang,Makiko Morita,Hiroo Ueno,Yusuke Shiozawa,Yuichi Shiraishi,Satoru Miyano,Rajeev Gupta,Katsutsugu Umeda,Kenichiro Watanabe,Katsuyoshi Koh,Souichi Adachi,Toshio Heike,Megumu K. Saito,Masashi Sanada,Seishi Ogawa,Teresa Marafioti,Akira Watanabe,Tatsutoshi Nakahata,Tariq Enver
Vitreous microRNA levels as diagnostic biomarkers for vitreoretinal lymphoma
Vinodh Kakkassery,Roland Schroers,Sarah E. Coupland,Marc-Ilan Wunderlich,Marc Schargus,Carsten Heinz,Susanne Wasmuth,Arnd Heiligenhaus,Guido Ahle,Patrick Lenoble,Uwe Schlegel,Wolff Schmiegel,H. Burkhard Dick,Alexander Baraniskin
BLOOD WORK
ERRATUM
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Cover Image
Cover Image
Representative immunofluorescence staining of a splenic germinal center (peanut agglutinin, red) with follicular helper T cells (CD4, green) and follicular regulatory T cells (Foxp3, white). The density of follicular regulatory T cells increases after infusion of invariant natural killer T cells. See the article by Du et al on page 3121.
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