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Anna M. Eiring
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Journal Articles

Targeting the Proteasomal 19S Regulatory Complex Instead of the 20S Catalytic Complex As a Novel Therapeutic Strategy in FLT3+ AML

Andres J Rubio, Mayra A. Gonzalez, Idaly M. Olivas, David Elliott, Mariah Black, Desiree N. Tapia, Andrea Orozco, Sharon Siby, Connor Jordan, Mehrshad Kevian, Alfredo Dominguez, Boronai Tychhon, Jesse C Allen, Anna M. Eiring
Journal: Blood
Blood (2024) 144 (Supplement 1): 5819.
https://doi.org/10.1182/blood-2024-208682
Published: 2024
Journal Articles

The Role of G0S2 in Lipid Metabolism Regulation in Chronic Myeloid Leukemia

Mayra A. Gonzalez, Idaly M. Olivas, Sara K. Dang, Anna M. Eiring
Journal: Blood
Blood (2023) 142 (Supplement 1): 5705.
https://doi.org/10.1182/blood-2023-187578
Published: 2023
Journal Articles

19S Proteasome Subunits As Oncogenes and Prognostic Biomarkers in FLT3-Mutated Acute Myeloid Leukemia (AML)

Joshua J. Lara, Alfonso E. Bencomo, Mayra A. Gonzalez, Idaly M. Olivas, Jose L. Lopez, James E. Young, Vanessa V. Velazquez, Steven Glovier, Andres J. Rubio, Sara K. Dang, Jonathan Solecki, Jesse Allen, Desiree N. Tapia, Boranai Tychhon, Gonzalo E. Astudillo, Darshan S. Chandrashekar, Anna M. Eiring
Journal: Blood
Blood (2022) 140 (Supplement 1): 3381–3382.
https://doi.org/10.1182/blood-2022-162818
Published: 2022
Journal Articles

Regulation of Oxidative Energy Metabolism By G0S2 in FLT3 + AML

Mayra A. Gonzalez, Jose L. Lopez, Vanessa V. Velazquez, Mariah Perkins, Idaly M. Olivas, Alfonso E. Bencomo, Andres J. Rubio, Jehu N. Apaflo, Sudip Bajpeyi, Anna M. Eiring
Journal: Blood
Blood (2022) 140 (Supplement 1): 2984–2985.
https://doi.org/10.1182/blood-2022-155560
Published: 2022
Journal Articles

MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis

Helong Zhao, Anthony D. Pomicter, Anna M. Eiring, Anca Franzini, Jonathan Ahmann, Jae-Yeon Hwang, Anna Senina, Bret Helton, Siddharth Iyer, Dongqing Yan, Jamshid S. Khorashad, Matthew S. Zabriskie, Anupriya Agarwal, Hannah M. Redwine, Amber D. Bowler, Phillip M. Clair, Shannon K. McWeeney, Brian J. Druker, Jeffrey W. Tyner, Derek L. Stirewalt, Vivian G. Oehler, Sooryanarayana Varambally, Kristofer C. Berrett, Jeffery M. Vahrenkamp, Jason Gertz, Katherine E. Varley, Jerald P. Radich, Michael W. Deininger
Journal: Blood
Blood (2022) 139 (5): 761–778.
https://doi.org/10.1182/blood.2021011802
Published: 2022
Includes: Supplemental data
Journal Articles

A Role for Lipid Metabolism in Tyrosine Kinase Inhibitor (TKI) Resistance of Chronic Myeloid Leukemia (CML)

Mayra A. Gonzalez, Jose L. Lopez, Katherine Schenkel, Kelaiah Reffell, Christopher A. Eide, Sudip Bajpeyi, Anna M. Eiring
Journal: Blood
Blood (2021) 138 (Supplement 1): 2542.
https://doi.org/10.1182/blood-2021-148507
Published: 2021
Journal Articles

MS4A3 Promotes Differentiation in Chronic Myeloid Leukemia By Enhancing Common β Chain Cytokine Receptor Endocytosis

Helong Zhao, Anthony D. Pomicter, Anna M. Eiring, Anca Franzini, Jonathan Ahmann, Jae-Yeon Hwang, Anna V. Senina, Bret Helton, Siddharth Iyer, Dongqing Yan, Jamshid Khorashad, Matthew S. Zabriskie, Anupriya Agarwal, Hannah M Redwine, Amber D. Bowler, Phillip M. Clair, Shannon K. McWeeney, Brian J. Druker, Jeffrey W. Tyner, Derek Stirewalt, Vivian G. Oehler, Sooryanarayana Varambally, Kristofer Berrett, Jeffrey Vahrenkamp, Jason Gertz, Katherine Varley, Jerald P. Radich, Michael W. Deininger
Journal: Blood
Blood (2021) 138 (Supplement 1): 59.
https://doi.org/10.1182/blood-2021-151559
Published: 2021
Journal Articles

NF-κB-Dependent Activation of the Proteasome Components, PSMD1 and PSMD3, As a Mechanism of Resistance to Imatinib

Idaly Maria Olivas, BS, Joshua Lara, BS, Rebecca Ellwood, MS, Carme Ripoll Fiol, MS, Andres J Rubio, MS, Alfonso Enrique Bencomo, PhD, Mayra Alejandra Gonzalez, BS, Georgios Nteliopoulos, PhD, Alistair Reid, BSc, PhD, Dragana Milojkovic, MBBS, MD, Jane Apperley, MB, ChB, MD, Jamshid Sorouri Khorashad, MD PhD FRCPath, Anna M. Eiring, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2923.
https://doi.org/10.1182/blood-2019-126963
Published: 2019
Journal Articles

Retrospective Study of Incidence and Survival for Patients with Hematologic Malignancies Residing at the U.S./Mexico Border

Alfonso Enrique Bencomo, PhD, Andres J Rubio, MS, Mayra Alejandra Gonzalez, BS, Idaly Maria Olivas, BS, Joshua Lara, BS, Kiran Ghimire, MD, Osvaldo Padilla, MD, Angelica Padilla, MD, Nawar Hakim, MD, Attilio Orazi, MD, Javier Corral, MD, Alexander Philipovskiy, MD PhD, Sumit Gaur, MBBS, Anna M. Eiring, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4782.
https://doi.org/10.1182/blood-2019-126150
Published: 2019
Journal Articles

Combining Dasatinib and AC220 Reduces Stroma-Based pSTAT5Y694 in FLT3-ITD+ AML and Overcomes FLT3 TKI Resistance

Ami B. Patel, MD, Anthony D. Pomicter, MS, Dongqing Yan, Anna M. Eiring, PhD, Anca Franzini, PhD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2641.
https://doi.org/10.1182/blood-2018-99-117276
Published: 2018
Journal Articles

Inhibition of Nucleocytoplasmic Export Enhances Selective Elimination of Leukemic Stem Cells in Chronic Myeloid Leukemia

Hein Than, MD FRCPath, MRCP, Anthony D. Pomicter, MS, Clinton C. Mason, PhD, Anna M. Eiring, PhD, William L. Heaton, MS, Dongqing Yan, Anna Senina, MS, Phillip M. Clair, MS, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 42.
https://doi.org/10.1182/blood.V130.Suppl_1.42.42
Published: 2017
Journal Articles

Selective Inhibition of Nucleocytoplasmic Transport Overcomes Ruxolitinib Resistance in Myelofibrosis

Dongqing Yan, Srinivas K. Tantravahi, MBBS, Anthony D. Pomicter, MS, Clinton C. Mason, PhD, Anna Senina, MS, Qiang Wang, PhD, Jamshid Sorouri Khorashad, MD PhD FRCPath, Hein Than, MD FRCPath, MRCP, Phillip M. Clair, MS, William L. Heaton, MS, Anna M. Eiring, PhD, Josef T. Prchal, MD, Sabina I. Swierczek, PhD, Erkan Baloglu, Sharon Shacham, PhD MBA, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1660.
https://doi.org/10.1182/blood.V130.Suppl_1.1660.1660
Published: 2017
Journal Articles

Loss of G0S2 in Kinase-Independent TKI Resistance and Blastic Transformation of CML

Anna M. Eiring, PhD, Jonathan Ahmann, Clinton C. Mason, PhD, Ethan Dmitrovsky, MD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4173.
https://doi.org/10.1182/blood.V130.Suppl_1.4173.4173
Published: 2017
Journal Articles

A Novel JAK2 Mutation Confers Cytokine-Independence in the Absence of a Type I Dimeric Cytokine Receptor

Ami B. Patel, MD, Anca Franzini, PhD, Emilie Leroy, PhD, Dongqing Yan, Anna M. Eiring, PhD, Stefan N. Constantinescu, MD PhD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4212.
https://doi.org/10.1182/blood.V130.Suppl_1.4212.4212
Published: 2017
Journal Articles

miR-155 promotes FLT3-ITD–induced myeloproliferative disease through inhibition of the interferon response

Jared A. Wallace, Dominique A. Kagele, Anna M. Eiring, Carissa N. Kim, Ruozhen Hu, Marah C. Runtsch, Margaret Alexander, Thomas B. Huffaker, Soh-Hyun Lee, Ami B. Patel, Timothy L. Mosbruger, Warren P. Voth, Dinesh S. Rao, Rodney R. Miles, June L. Round, Michael W. Deininger, Ryan M. O’Connell
Journal: Blood
Blood (2017) 129 (23): 3074–3086.
https://doi.org/10.1182/blood-2016-09-740209
Published: 2017
Journal Articles

Stroma-Based Activation of pSTAT3 Y705 Confers Resistance to FLT3 Inhibitors in FLT3 ITD-Positive AML

Ami Patel, MD, Anthony D. Pomicter, MS, Anna M. Eiring, PhD, Than Hein, MBBS, William L. Heaton, MS, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2016) 128 (22): 34.
https://doi.org/10.1182/blood.V128.22.34.34
Published: 2016
Journal Articles

Selective Inhibition of Nuclear Cytoplasmic Transport As a New Treatment Paradigm in Myelofibrosis

Dongqing Yan, PhD, Srinivas K. Tantravahi, MD, Anthony D. Pomicter, MS, Anna Senina, MS, Kevin C. Gantz, Hannah M. Redwine, Josef T. Prchal, MD, Sabina Swierczek, PhD, Phillip M. Clair, MS, Anna M. Eiring, PhD, Erkan Baloglu, PhD MBA, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2016) 128 (22): 636.
https://doi.org/10.1182/blood.V128.22.636.636
Published: 2016
Journal Articles

MS4A3: A New Player in Leukemic Stem Cell Survival in Chronic Myeloid Leukemia

Anna M. Eiring, PhD, Jamshid S. Khorashad, MD PhD, Anupriya Agarwal, PhD, Clinton C. Mason, PhD, Russell Bell, PhD, Anna Senina, MS, Anthony D. Pomicter, MS, Fan Yu, MD, Hannah M. Redwine, Amber D. Bowler, Phillip M. Clair, MS, Srinivas K. Tantravahi, MD, Shannon K. McWeeney, Brian J. Druker, MD, Derek L. Stirewalt, Vivian Oehler, MD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2016) 128 (22): 934.
https://doi.org/10.1182/blood.V128.22.934.934
Published: 2016
Journal Articles

MS4A3 Improves Imatinib Response and Survival in BCR-ABL1 Primary TKI Resistance and in Blastic Transformation of Chronic Myeloid Leukemia

Anna M. Eiring, PhD, Jamshid S. Khorashad, MD PhD, Anupriya Agarwal, PhD, Clinton C. Mason, PhD, Fan Yu, MD, Hannah M. Redwine, Amber D. Bowler, Kevin C. Gantz, Kimberly R. Reynolds, MS, Phillip M. Clair, MS, David J. Anderson, MBA, Srinivas K Tantravahi, Shannon K. McWeeney, PhD, Brian J. Druker, MD, Derek L. Stirewalt, MD, Vivian G. Oehler, MD, Thomas O'Hare, PhD, Michael W. Deininger
Journal: Blood
Blood (2015) 126 (23): 14.
https://doi.org/10.1182/blood.V126.23.14.14
Published: 2015
Journal Articles

Transition of Chronic Myeloid Leukemia to Chronic Myelomonocytic Leukemia As a Tool to Observe Development of Chronic Myelomonocytic Leukemia

Jamshid S Khorashad, MD PhD, Srinivas K Tantravahi, Dongqing Yan, PhD, Anna M. Eiring, PhD, Hannah M. Redwine, Amber D. Bowler, Kevin C. Gantz, Keith M Gligorich, PhD, Anthony D Pomicter, MS, Todd W Kelley, MD, Thomas O'Hare, PhD, Michael W Deininger, MD PhD
Journal: Blood
Blood (2015) 126 (23): 5223.
https://doi.org/10.1182/blood.V126.23.5223.5223
Published: 2015