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Matthew S. Zabriskie
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Journal Articles

MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis

Helong Zhao, Anthony D. Pomicter, Anna M. Eiring, Anca Franzini, Jonathan Ahmann, Jae-Yeon Hwang, Anna Senina, Bret Helton, Siddharth Iyer, Dongqing Yan, Jamshid S. Khorashad, Matthew S. Zabriskie, Anupriya Agarwal, Hannah M. Redwine, Amber D. Bowler, Phillip M. Clair, Shannon K. McWeeney, Brian J. Druker, Jeffrey W. Tyner, Derek L. Stirewalt, Vivian G. Oehler, Sooryanarayana Varambally, Kristofer C. Berrett, Jeffery M. Vahrenkamp, Jason Gertz, Katherine E. Varley, Jerald P. Radich, Michael W. Deininger
Journal: Blood
Blood (2022) 139 (5): 761–778.
https://doi.org/10.1182/blood.2021011802
Published: 2022
Includes: Supplemental data
Journal Articles

MS4A3 Promotes Differentiation in Chronic Myeloid Leukemia By Enhancing Common β Chain Cytokine Receptor Endocytosis

Helong Zhao, Anthony D. Pomicter, Anna M. Eiring, Anca Franzini, Jonathan Ahmann, Jae-Yeon Hwang, Anna V. Senina, Bret Helton, Siddharth Iyer, Dongqing Yan, Jamshid Khorashad, Matthew S. Zabriskie, Anupriya Agarwal, Hannah M Redwine, Amber D. Bowler, Phillip M. Clair, Shannon K. McWeeney, Brian J. Druker, Jeffrey W. Tyner, Derek Stirewalt, Vivian G. Oehler, Sooryanarayana Varambally, Kristofer Berrett, Jeffrey Vahrenkamp, Jason Gertz, Katherine Varley, Jerald P. Radich, Michael W. Deininger
Journal: Blood
Blood (2021) 138 (Supplement 1): 59.
https://doi.org/10.1182/blood-2021-151559
Published: 2021
Journal Articles

Combining the Allosteric ABL1 Inhibitor Asciminib (ABL001) with Ponatinib Suppresses Emergence of and Restores Efficacy Against Highly Resistant BCR-ABL1 Compound Mutants

Christopher A. Eide, Matthew S. Zabriskie, Samantha L. Savage, Orlando Antelope, Nadeem A. Vellore, Hein Than, Anna Reister Schultz, Phillip M. Clair, Amber D. Bowler, Anthony D. Pomicter, Dongqing Yan, Anna V. Senina, Qiang Wang, Todd W. Kelley, Philippe Szankasi, Michael C. Heinrich, Jeffrey W. Tyner, Delphine Rea, MD, Jean-Michel Cayuela, Dong-Wook Kim, Cristina E. Tognon, Thomas O'Hare, PhD, Brian J. Druker, Michael W. Deininger
Journal: Blood
Blood (2019) 134 (Supplement_1): 188.
https://doi.org/10.1182/blood-2019-131781
Published: 2019
Journal Articles

Characterization of the Genomic Landscape of BCR-ABL1 Kinase-Independent Mechanisms of Resistance to ABL1 Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia

Christopher A. Eide, Daniel Bottomly, Samantha L. Savage, Libbey White, Beth Wilmot, Anna M. Reister Schultz, Kimberly A. Uchida, Anupriya Agarwal, Elie Traer, MD, Lan Beppu, Olga Sala-Torra, Jerald P. Radich, Garrett Eickelberg, Richard D. Press, Marc M. Loriaux, Srinivas K. Tantravahi, MD, Anthony D. Pomicter, MS, Matthew S. Zabriskie, Michael W. Deininger, MD PhD, Thomas O'Hare, PhD, Jeffrey W. Tyner, Shannon K. McWeeney, Cristina E. Tognon, Brian J. Druker
Journal: Blood
Blood (2016) 128 (22): 1119.
https://doi.org/10.1182/blood.V128.22.1119.1119
Published: 2016
Journal Articles

Bull's-Eyes and Blind Spots: Pre-Clinical Studies with the Allosteric Inhibitor ABL001 in BCR-ABL1 Compound Mutation-Based Resistance

O'Hare Thomas, PhD, Matthew S. Zabriskie, Christopher A. Eide, Nadeem A. Vellore, PhD, Brian J. Druker, MD, Michael W Deininger, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1565.
https://doi.org/10.1182/blood.V126.23.1565.1565
Published: 2015
Journal Articles

shRNA library screening identifies nucleocytoplasmic transport as a mediator of BCR-ABL1 kinase-independent resistance

Jamshid S. Khorashad, Anna M. Eiring, Clinton C. Mason, Kevin C. Gantz, Amber D. Bowler, Hannah M. Redwine, Fan Yu, Ira L. Kraft, Anthony D. Pomicter, Kimberly R. Reynolds, Anthony J. Iovino, Matthew S. Zabriskie, William L. Heaton, Srinivas K. Tantravahi, Michael Kauffman, Sharon Shacham, Alex Chenchik, Kyle Bonneau, Katharine S. Ullman, Thomas O’Hare, Michael W. Deininger
Journal: Blood
Blood (2015) 125 (11): 1772–1781.
https://doi.org/10.1182/blood-2014-08-588855
Published: 2015
Includes: Supplemental data
Journal Articles

Next Generation Sequencing to Delineate the Mutational Landscape of Chronic Myelomonocytic Leukemia (CMML): Novel Disease Genes and Correlations with Survival

Clinton C. Mason, PhD, Jamshid S. Khorashad, MD PhD, Srinivas K. Tantravahi, MD, Todd W. Kelley, MD, Anthony D. Pomicter, M.S., Anthony J. Iovino, Kimberly R. Reynolds, M.S., Anna M. Eiring, PhD, Matthew S. Zabriskie, BS, Zev Kronenberg, Jeffrey W. Tyner, Brian Dalley, PhD, Kim-Hien T. Dao, DO,PhD, Thomas O'Hare, PhD, Mark Yandell, PhD, Brian J. Druker, Jason R. Gotlib, MD, Michael W. Deininger
Journal: Blood
Blood (2014) 124 (21): 4637.
https://doi.org/10.1182/blood.V124.21.4637.4637
Published: 2014
Journal Articles

An Unbiased shRNA Library Screen Identifies Nucleocytoplasmic Transport As a Potential Target For Treatment Of Chronic Myeloid Leukemia

Jamshid Sorouri Khorashad, MD, PhD, FRCPath, Clinton C. Mason, PhD, Ira L. Kraft, BS, Kimberly R. Reynolds, MS, Anthony D. Pomicter, MS, Anna M. Eiring, PhD, Matthew S. Zabriskie, Anthony J Iovino, William Heaton, Srinivas K. Tantravahi, MBBS, MRCP, Michael Kauffman, MD, PhD, Sharon Schacham, PhD, MBA, Alex Chenchik, PhD, Kyle Bonneau, PhD, Thomas O'Hare, Michael W. Deininger, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2707.
https://doi.org/10.1182/blood.V122.21.2707.2707
Published: 2013
Journal Articles

BP5-087, a Novel STAT3 Inhibitor, Combines With BCR-ABL1 Inhibition To Overcome Kinase-Independent Resistance In Chronic Myeloid Leukemia

Anna M. Eiring, PhD, Ira L. Kraft, BS, Brent D.G. Page, PhD, Tian Y. Zhang, MD, PhD, Jamshid S. Khorashad, MD, PhD, FRCPath, Nadeem A. Vellore, PhD, Kimberly R. Reynolds, MS, Anthony D. Pomicter, MS, Anna V. Senina, MS, Matthew S. Zabriskie, BS, Shazia Ahmad, Clinton C. Mason, PhD, Richard Moriggl, PhD, Riccardo Baron, PhD, Thomas O'Hare, Patrick T. Gunning, PhD, Michael W. Deininger
Journal: Blood
Blood (2013) 122 (21): 854.
https://doi.org/10.1182/blood.V122.21.854.854
Published: 2013
Journal Articles

BCR-ABL1 compound mutations in tyrosine kinase inhibitor–resistant CML: frequency and clonal relationships

Jamshid S. Khorashad, Todd W. Kelley, Philippe Szankasi, Clinton C. Mason, Simona Soverini, Lauren T. Adrian, Christopher A. Eide, Matthew S. Zabriskie, Thoralf Lange, Johanna C. Estrada, Anthony D. Pomicter, Anna M. Eiring, Ira L. Kraft, David J. Anderson, Zhimin Gu, Mary Alikian, Alistair G. Reid, Letizia Foroni, David Marin, Brian J. Druker, Thomas O'Hare, Michael W. Deininger
Journal: Blood
Blood (2013) 121 (3): 489–498.
https://doi.org/10.1182/blood-2012-05-431379
Published: 2013
Includes: Supplemental data
Journal Articles

STAT3 Inhibition Synergizes with BCR-ABL1 Inhibition to Overcome Kinase-Independent TKI Resistance in Chronic Myeloid Leukemia (CML)

Anna M. Eiring, PhD, Ira L Kraft, BS, Brent DG Page, BS, David J Anderson, BA, Zhimin Gu, PhD, Jamshid S Khorashad, MD, PhD, Anthony D Pomicter, MS, Kimberly R Reynolds, MS, Matthew S Zabriskie, BS, Richard Moriggl, PhD, Patrick T Gunning, PhD, Thomas O'Hare, PhD, Michael W Deininger, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 31.
https://doi.org/10.1182/blood.V120.21.31.31
Published: 2012
Journal Articles

Next-Generation STAT3 Inhibitors As Targeted Therapeutics in Chronic Myeloid Leukemia.

Ira L Kraft, BS, Anna M. Eiring, PhD, Brent DG Page, BS, Clinton C Mason, PhD, Zhimin Gu, PhD, Jamshid S Khorashad, MD, PhD, David J Anderson, BA, Anthony D Pomicter, MS, Kimberly R Reynolds, MS, Johanna Estrada, Matthew S Zabriskie, BS, Patrick T Gunning, PhD, Thomas O'Hare, PhD, Michael W Deininger, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2445.
https://doi.org/10.1182/blood.V120.21.2445.2445
Published: 2012
Journal Articles

Partially or Fully BCR-ABL Independent Mechanisms of in Vitro Resistance to Ponatinib

Qian Yu, BS, Anna M Eiring, PhD, Matthew S. Zabriskie, Jamshid Khorashad, MD, PhD, David J Anderson, BS, Jade A Bryant, BS, Marc M Loriaux, MD, PhD, Jeffrey W Tyner, PhD, Thomas O'Hare, Michael W. Deininger
Journal: Blood
Blood (2011) 118 (21): 2481.
https://doi.org/10.1182/blood.V118.21.2481.2481
Published: 2011
Journal Articles

Frequency and Clonality of BCR-ABL Compound Mutations in Chronic Myeloid Leukemia,

Jamshid Khorashad, MD, PhD, Todd W. Kelley, MD, Philippe Szankasi, PhD, Lauren T. Adrian, Christopher A. Eide, Matthew S. Zabriskie, Thoralf Lange, MD, Ira L Kraft, BS, Anna M Eiring, PhD, Thomas O'Hare, Michael W. Deininger
Journal: Blood
Blood (2011) 118 (21): 3744.
https://doi.org/10.1182/blood.V118.21.3744.3744
Published: 2011
Journal Articles

Cryptic Intracellular Retention of ABL Tyrosine Kinase Inhibitors within CML Cells Mediates Apoptosis Commitment Following Acute Drug Exposure,

Thomas O'Hare, Christopher A. Eide, Lauren T. Adrian, Anupriya Agarwal, PhD, Matthew S. Zabriskie, Ryan MacKenzie, BS, Dorian H. LaTocha, BS, Huihong You, PhD, Jenny Luo, BS, Steven M. Riddle, PhD, Bryan Marks, PhD, Dennis R. Koop, PhD, John Apgar, PhD, Michael W. Deininger, Brian J. Druker
Journal: Blood
Blood (2011) 118 (21): 3504.
https://doi.org/10.1182/blood.V118.21.3504.3504
Published: 2011
Journal Articles

Resistance Profiling of BCR-ABL Compound Mutations Linked to Tyrosine Kinase Inhibitor Therapy Failure in Chronic Myeloid Leukemia

Christopher A. Eide, Matthew S. Zabriskie, Lauren T. Adrian, Thoralf Lange, Michael W. Deininger, Brian J. Druker, Thomas O'Hare
Journal: Blood
Blood (2011) 118 (21): 1416.
https://doi.org/10.1182/blood.V118.21.1416.1416
Published: 2011
Journal Articles

The BCR-ABL 35INS insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia

Brief Report
Thomas O'Hare, Matthew S. Zabriskie, Christopher A. Eide, Anupriya Agarwal, Lauren T. Adrian, Huihong You, Amie S. Corbin, Fei Yang, Richard D. Press, Victor M. Rivera, Julie Toplin, Stephane Wong, Michael W. Deininger, Brian J. Druker
Journal: Blood
Blood (2011) 118 (19): 5250–5254.
https://doi.org/10.1182/blood-2011-05-349191
Published: 2011
Includes: Supplemental data