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Lauren T. Adrian
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Journal Articles

BCR-ABL1 compound mutations in tyrosine kinase inhibitor–resistant CML: frequency and clonal relationships

Jamshid S. Khorashad, Todd W. Kelley, Philippe Szankasi, Clinton C. Mason, Simona Soverini, Lauren T. Adrian, Christopher A. Eide, Matthew S. Zabriskie, Thoralf Lange, Johanna C. Estrada, Anthony D. Pomicter, Anna M. Eiring, Ira L. Kraft, David J. Anderson, Zhimin Gu, Mary Alikian, Alistair G. Reid, Letizia Foroni, David Marin, Brian J. Druker, Thomas O'Hare, Michael W. Deininger
Journal: Blood
Blood (2013) 121 (3): 489–498.
https://doi.org/10.1182/blood-2012-05-431379
Published: 2013
Includes: Supplemental data
Journal Articles

Frequency and Clonality of BCR-ABL Compound Mutations in Chronic Myeloid Leukemia,

Jamshid Khorashad, MD, PhD, Todd W. Kelley, MD, Philippe Szankasi, PhD, Lauren T. Adrian, Christopher A. Eide, Matthew S. Zabriskie, Thoralf Lange, MD, Ira L Kraft, BS, Anna M Eiring, PhD, Thomas O'Hare, Michael W. Deininger
Journal: Blood
Blood (2011) 118 (21): 3744.
https://doi.org/10.1182/blood.V118.21.3744.3744
Published: 2011
Journal Articles

Cryptic Intracellular Retention of ABL Tyrosine Kinase Inhibitors within CML Cells Mediates Apoptosis Commitment Following Acute Drug Exposure,

Thomas O'Hare, Christopher A. Eide, Lauren T. Adrian, Anupriya Agarwal, PhD, Matthew S. Zabriskie, Ryan MacKenzie, BS, Dorian H. LaTocha, BS, Huihong You, PhD, Jenny Luo, BS, Steven M. Riddle, PhD, Bryan Marks, PhD, Dennis R. Koop, PhD, John Apgar, PhD, Michael W. Deininger, Brian J. Druker
Journal: Blood
Blood (2011) 118 (21): 3504.
https://doi.org/10.1182/blood.V118.21.3504.3504
Published: 2011
Journal Articles

Resistance Profiling of BCR-ABL Compound Mutations Linked to Tyrosine Kinase Inhibitor Therapy Failure in Chronic Myeloid Leukemia

Christopher A. Eide, Matthew S. Zabriskie, Lauren T. Adrian, Thoralf Lange, Michael W. Deininger, Brian J. Druker, Thomas O'Hare
Journal: Blood
Blood (2011) 118 (21): 1416.
https://doi.org/10.1182/blood.V118.21.1416.1416
Published: 2011
Journal Articles

The BCR-ABL 35INS insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia

Brief Report
Thomas O'Hare, Matthew S. Zabriskie, Christopher A. Eide, Anupriya Agarwal, Lauren T. Adrian, Huihong You, Amie S. Corbin, Fei Yang, Richard D. Press, Victor M. Rivera, Julie Toplin, Stephane Wong, Michael W. Deininger, Brian J. Druker
Journal: Blood
Blood (2011) 118 (19): 5250–5254.
https://doi.org/10.1182/blood-2011-05-349191
Published: 2011
Includes: Supplemental data
Journal Articles

Acute dasatinib exposure commits Bcr-Abl–dependent cells to apoptosis

Jennifer L. Snead, Thomas O'Hare, Lauren T. Adrian, Christopher A. Eide, Thoralf Lange, Brian J. Druker, Michael W. Deininger
Journal: Blood
Blood (2009) 114 (16): 3459–3463.
https://doi.org/10.1182/blood-2007-10-113969
Published: 2009
Includes: Supplemental data
Journal Articles

Complete Suppression of in Vitro Resistance by AP24534, a Pan-BCR-ABL Inhibitor

Thomas O’Hare, Christopher A. Eide, Lauren T. Adrian, Victor M. Rivera, William C. Shakespeare, Tim Clackson, Michael W. N. Deininger, Brian J. Druker
Journal: Blood
Blood (2008) 112 (11): 726.
https://doi.org/10.1182/blood.V112.11.726.726
Published: 2008