Jean-François Emile,for the Histiocyte Society,Oussama Abla,for the Histiocyte Society,Sylvie Fraitag,for the Histiocyte Society,Annacarin Horne,for the Histiocyte Society,Julien Haroche,for the Histiocyte Society,Jean Donadieu,for the Histiocyte Society,Luis Requena-Caballero,for the Histiocyte Society,Michael B. Jordan,for the Histiocyte Society,Omar Abdel-Wahab,for the Histiocyte Society,Carl E. Allen,for the Histiocyte Society,Frédéric Charlotte,for the Histiocyte Society,Eli L. Diamond,for the Histiocyte Society,R. Maarten Egeler,for the Histiocyte Society,Alain Fischer,for the Histiocyte Society,Juana Gil Herrera,for the Histiocyte Society,Jan-Inge Henter,for the Histiocyte Society,Filip Janku,for the Histiocyte Society,Miriam Merad,for the Histiocyte Society,Jennifer Picarsic,for the Histiocyte Society,Carlos Rodriguez-Galindo,for the Histiocyte Society,Barret J. Rollins,for the Histiocyte Society,Abdellatif Tazi,for the Histiocyte Society,Robert Vassallo,for the Histiocyte Society,Lawrence M. Weiss,for the Histiocyte Society

View Articletitled, Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages

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HOW I TREAT

How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantation
Clinical Trials & Observations

Alpana Waghmare,Janet A. Englund,Michael Boeckh

View Articletitled, How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantation

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CLINICAL TRIALS AND OBSERVATIONS

Phase 1 study of marizomib in relapsed or relapsed and refractory multiple myeloma: NPI-0052-101 Part 1
Clinical Trials & Observations

Paul G. Richardson,Todd M. Zimmerman,Craig C. Hofmeister,Moshe Talpaz,Asher A. Chanan-Khan,Jonathan L. Kaufman,Jacob P. Laubach,Dharminder Chauhan,Andrzej J. Jakubowiak,Steven Reich,Mohit Trikha,Kenneth C. Anderson

View Articletitled, Phase 1 study of marizomib in relapsed or relapsed and refractory multiple myeloma: NPI-0052-101 Part 1

IMMUNOBIOLOGY

Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome

Satu Hyvärinen,Seppo Meri,T. Sakari Jokiranta

View Articletitled, Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome

LYMPHOID NEOPLASIA

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

Seongseok Yun,Nicole D. Vincelette,Katherine L. B. Knorr,Luciana L. Almada,Paula A. Schneider,Kevin L. Peterson,Karen S. Flatten,Haiming Dai,Keith W. Pratz,Allan D. Hess,B. Douglas Smith,Judith E. Karp,Andrea E. Wahner Hendrickson,Martin E. Fernandez-Zapico,Scott H. Kaufmann

View Articletitled, 4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

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GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo

Jane A. Healy,Adrienne Nugent,Rachel E. Rempel,Andrea B. Moffitt,Nicholas S. Davis,Xiaoyu Jiang,Jennifer R. Shingleton,Jenny Zhang,Cassandra Love,Jyotishka Datta,Matthew E. McKinney,Tiffany J. Tzeng,Nina Wettschureck,Stefan Offermanns,Katelyn A. Walzer,Jen-Tsan Chi,Suhail A. K. Rasheed,Patrick J. Casey,Izidore S. Lossos,Sandeep S. Dave

View Articletitled, GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo

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B-cell–specific conditional expression of Myd88^p.L252P leads to the development of diffuse large B-cell lymphoma in mice

Gero Knittel,Paul Liedgens,Darya Korovkina,Jens M. Seeger,Yussor Al-Baldawi,Mona Al-Maarri,Christian Fritz,Katerina Vlantis,Svetlana Bezhanova,Andreas H. Scheel,Olaf-Oliver Wolz,Maurice Reimann,Peter Möller,Cristina López,Matthias Schlesner,Philipp Lohneis,Alexander N. R. Weber,Lorenz Trümper,German International Cancer Genome Consortium Molecular Mechanisms in Malignant Lymphoma by Sequencing Project Consortium,Louis M. Staudt,Monika Ortmann,Manolis Pasparakis,Reiner Siebert,Clemens A. Schmitt,Andreas R. Klatt,F. Thomas Wunderlich,Stephan C. Schäfer,Thorsten Persigehl,Manuel Montesinos-Rongen,Margarete Odenthal,Reinhard Büttner,Lukas P. Frenzel,Hamid Kashkar,H. Christian Reinhardt

View Articletitled, B-cell–specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice

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MYELOID NEOPLASIA

Risk stratification of chromosomal abnormalities in chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy

Wei Wang,Jorge E. Cortes,Guilin Tang,Joseph D. Khoury,Sa Wang,Carlos E. Bueso-Ramos,Joseph A. DiGiuseppe,Zi Chen,Hagop M. Kantarjian,L. Jeffrey Medeiros,Shimin Hu

View Articletitled, Risk stratification of chromosomal abnormalities in chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy

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THROMBOSIS AND HEMOSTASIS

Fibrin deposition following bile duct injury limits fibrosis through an α_Mβ₂-dependent mechanism

Nikita Joshi,Anna K. Kopec,Jessica L. Ray,Holly Cline-Fedewa,Atta Nawabi,Timothy Schmitt,Rance Nault,Timothy R. Zacharewski,Cheryl E. Rockwell,Matthew J. Flick,James P. Luyendyk

View Articletitled, Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism

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Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury–associated coagulopathy in mice

Zilong Zhao,Min Wang,Ye Tian,Tristan Hilton,Breia Salsbery,Eric Z. Zhou,Xiaoping Wu,Perumal Thiagarajan,Eric Boilard,Min Li,Jianning Zhang,Jing-fei Dong

View Articletitled, Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury–associated coagulopathy in mice

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LETTERS TO BLOOD

Paper or plastic? BCR-ABL1 quantitation and mutation detection from dried blood spots

Olga Sala Torra,Lan Beppu,Jordan L. Smith,Linda Welden,Jasmina Georgievski,Karisma Gupta,Rashmi Kumar,Cecilia C. S. Yeung,Amy Paguirigan,Ted A. Gooley,Susan Branford,Jerald P. Radich

View Articletitled, Paper or plastic? BCR-ABL1 quantitation and mutation detection from dried blood spots

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BLOOD WORK

Hemophagocytic lymphohistiocytosis secondary to iatrogenic disseminated histoplasmosis

Linda N. Dao,Rong He

View Articletitled, Hemophagocytic lymphohistiocytosis secondary to iatrogenic disseminated histoplasmosis

Deformation of erythroblasts in transient erythroblastopenia of childhood caused by HHV-6

Akira Ogawa,Ryu Yanagisawa

View Articletitled, Deformation of erythroblasts in transient erythroblastopenia of childhood caused by HHV-6

ERRATA

Chen Z, Orlowski RZ, Wang M, Kwak L, McCarty N. Osteoblastic niche supports the growth of quiescent multiple myeloma cells. Blood. 2014;123(14):2204-2208.

View Articletitled, Chen Z, Orlowski RZ, Wang M, Kwak L, McCarty N. Osteoblastic niche supports the growth of quiescent multiple myeloma cells. Blood. 2014;123(14):2204-2208.

Gill JC, Castaman G, Windyga J, et al. Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease. Blood. 2015;126(17):2038-2046.

View Articletitled, Gill JC, Castaman G, Windyga J, et al. Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease. Blood. 2015;126(17):2038-2046.

Cover Image

Cover Image

B-cell–specific conditional expression of Myd88^p.L252P (the murine orthologue of the human p.L265P point mutation) in combination with overexpression of BCL2 in B cells leads to the emergence of activated B cell diffuse large B-cell lymphoma in mice. The developing lymphomas stain positive for Cd138, as it is shown in this immunohistochemical staining of a heavily infiltrated liver. See the article by Knittel et al on page 2732.
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