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Issue Archive

Volume 127, Issue 22
June 2 2016
Issue Cover

Table of Contents

ANNIVERSARY EDITORIAL

Blood's 70th anniversary: musings of a Blood editor, 2003-2007
Sanford J. Shattil
View Articletitled, <em>Blood</em>'s 70th anniversary: musings of a <em>Blood</em> editor, 2003-2007

BLOOD FLASHBACK

Goodman JW, Hodgson GS. Evidence for stem cells in the peripheral blood of mice. Blood. 1962;19(6):702-714.
View Articletitled, Goodman JW, Hodgson GS. Evidence for stem cells in the peripheral blood of mice. <em>Blood</em>. 1962;19(6):<span class="related-article">702-714</span>.

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
The histiocytoses: as easy as ABC (or LCMRH)
John L. Frater
View Articletitled, The histiocytoses: as easy as ABC (or LCMRH)
INSIDE BLOOD COMMENTARY
Sweeteners for factor H
Edward M. Conway
View Articletitled, Sweeteners for factor H
INSIDE BLOOD COMMENTARY
mTOR signaling: new networks for ALL
David A. Fruman
View Articletitled, mTOR signaling: new networks for ALL
INSIDE BLOOD COMMENTARY
Mouse model of MYD88L265P-dependent DLBCL
Siegfried Janz
View Articletitled, Mouse model of MYD88<sup>L265P</sup>-dependent DLBCL
INSIDE BLOOD COMMENTARY
Cytogenetics in CML: more important than you think
François Guilhot
View Articletitled, Cytogenetics in CML: more important than you think
INSIDE BLOOD COMMENTARY
Fibrin fixes fibrosis
Ton Lisman
View Articletitled, Fibrin fixes fibrosis

PERSPECTIVES

Personalized medicine in thrombosis: back to the future
Srikanth Nagalla,Paul F. Bray
View Articletitled, Personalized medicine in thrombosis: back to the future

REVIEW ARTICLE

Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages
Clinical Trials & Observations
Jean-François Emile,Oussama Abla,Sylvie Fraitag,Annacarin Horne,Julien Haroche,Jean Donadieu,Luis Requena-Caballero,Michael B. Jordan,Omar Abdel-Wahab,Carl E. Allen,Frédéric Charlotte,Eli L. Diamond,R. Maarten Egeler,Alain Fischer,Juana Gil Herrera,Jan-Inge Henter,Filip Janku,Miriam Merad,Jennifer Picarsic,Carlos Rodriguez-Galindo,Barret J. Rollins,Abdellatif Tazi,Robert Vassallo,Lawrence M. Weiss,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society,for the Histiocyte Society
View Articletitled, Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages
Supplemental data

HOW I TREAT

How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantation
Clinical Trials & Observations
Alpana Waghmare,Janet A. Englund,Michael Boeckh
View Articletitled, How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantation
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Phase 1 study of marizomib in relapsed or relapsed and refractory multiple myeloma: NPI-0052-101 Part 1
Clinical Trials & Observations
Paul G. Richardson,Todd M. Zimmerman,Craig C. Hofmeister,Moshe Talpaz,Asher A. Chanan-Khan,Jonathan L. Kaufman,Jacob P. Laubach,Dharminder Chauhan,Andrzej J. Jakubowiak,Steven Reich,Mohit Trikha,Kenneth C. Anderson
View Articletitled, Phase 1 study of marizomib in relapsed or relapsed and refractory multiple myeloma: NPI-0052-101 Part 1

IMMUNOBIOLOGY

Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome
Satu Hyvärinen,Seppo Meri,T. Sakari Jokiranta
View Articletitled, Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome

LYMPHOID NEOPLASIA

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells
Seongseok Yun,Nicole D. Vincelette,Katherine L. B. Knorr,Luciana L. Almada,Paula A. Schneider,Kevin L. Peterson,Karen S. Flatten,Haiming Dai,Keith W. Pratz,Allan D. Hess,B. Douglas Smith,Judith E. Karp,Andrea E. Wahner Hendrickson,Martin E. Fernandez-Zapico,Scott H. Kaufmann
View Articletitled, 4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells
Supplemental data
GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo
Jane A. Healy,Adrienne Nugent,Rachel E. Rempel,Andrea B. Moffitt,Nicholas S. Davis,Xiaoyu Jiang,Jennifer R. Shingleton,Jenny Zhang,Cassandra Love,Jyotishka Datta,Matthew E. McKinney,Tiffany J. Tzeng,Nina Wettschureck,Stefan Offermanns,Katelyn A. Walzer,Jen-Tsan Chi,Suhail A. K. Rasheed,Patrick J. Casey,Izidore S. Lossos,Sandeep S. Dave
View Articletitled, GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo
Supplemental data
B-cell–specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice
Gero Knittel,Paul Liedgens,Darya Korovkina,Jens M. Seeger,Yussor Al-Baldawi,Mona Al-Maarri,Christian Fritz,Katerina Vlantis,Svetlana Bezhanova,Andreas H. Scheel,Olaf-Oliver Wolz,Maurice Reimann,Peter Möller,Cristina López,Matthias Schlesner,Philipp Lohneis,Alexander N. R. Weber,Lorenz Trümper,German International Cancer Genome Consortium Molecular Mechanisms in Malignant Lymphoma by Sequencing Project Consortium,Louis M. Staudt,Monika Ortmann,Manolis Pasparakis,Reiner Siebert,Clemens A. Schmitt,Andreas R. Klatt,F. Thomas Wunderlich,Stephan C. Schäfer,Thorsten Persigehl,Manuel Montesinos-Rongen,Margarete Odenthal,Reinhard Büttner,Lukas P. Frenzel,Hamid Kashkar,H. Christian Reinhardt
View Articletitled, B-cell–specific conditional expression of <em>Myd88</em><sup><em>p.L252P</em></sup> leads to the development of diffuse large B-cell lymphoma in mice
Supplemental data

MYELOID NEOPLASIA

Risk stratification of chromosomal abnormalities in chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy
Wei Wang,Jorge E. Cortes,Guilin Tang,Joseph D. Khoury,Sa Wang,Carlos E. Bueso-Ramos,Joseph A. DiGiuseppe,Zi Chen,Hagop M. Kantarjian,L. Jeffrey Medeiros,Shimin Hu
View Articletitled, Risk stratification of chromosomal abnormalities in chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy
Supplemental data

THROMBOSIS AND HEMOSTASIS

Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism
Nikita Joshi,Anna K. Kopec,Jessica L. Ray,Holly Cline-Fedewa,Atta Nawabi,Timothy Schmitt,Rance Nault,Timothy R. Zacharewski,Cheryl E. Rockwell,Matthew J. Flick,James P. Luyendyk
View Articletitled, Fibrin deposition following bile duct injury limits fibrosis through an α<sub>M</sub>β<sub>2</sub>-dependent mechanism
Supplemental data
Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury–associated coagulopathy in mice
Zilong Zhao,Min Wang,Ye Tian,Tristan Hilton,Breia Salsbery,Eric Z. Zhou,Xiaoping Wu,Perumal Thiagarajan,Eric Boilard,Min Li,Jianning Zhang,Jing-fei Dong
View Articletitled, Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury–associated coagulopathy in mice
Supplemental data

LETTERS TO BLOOD

Paper or plastic? BCR-ABL1 quantitation and mutation detection from dried blood spots
Olga Sala Torra,Lan Beppu,Jordan L. Smith,Linda Welden,Jasmina Georgievski,Karisma Gupta,Rashmi Kumar,Cecilia C. S. Yeung,Amy Paguirigan,Ted A. Gooley,Susan Branford,Jerald P. Radich
View Articletitled, Paper or plastic? BCR-ABL1 quantitation and mutation detection from dried blood spots
Supplemental data

BLOOD WORK

Hemophagocytic lymphohistiocytosis secondary to iatrogenic disseminated histoplasmosis
Linda N. Dao,Rong He
View Articletitled, Hemophagocytic lymphohistiocytosis secondary to iatrogenic disseminated histoplasmosis
Deformation of erythroblasts in transient erythroblastopenia of childhood caused by HHV-6
Akira Ogawa,Ryu Yanagisawa
View Articletitled, Deformation of erythroblasts in transient erythroblastopenia of childhood caused by HHV-6

ERRATA

Chen Z, Orlowski RZ, Wang M, Kwak L, McCarty N. Osteoblastic niche supports the growth of quiescent multiple myeloma cells. Blood. 2014;123(14):2204-2208.
View Articletitled, Chen Z, Orlowski RZ, Wang M, Kwak L, McCarty N. Osteoblastic niche supports the growth of quiescent multiple myeloma cells. <em>Blood</em>. 2014;123(14):2204-2208.
Gill JC, Castaman G, Windyga J, et al. Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease. Blood. 2015;126(17):2038-2046.
View Articletitled, Gill JC, Castaman G, Windyga J, et al. Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease. <em>Blood.</em> 2015;126(17):2038-2046.
  • Cover Image

    Cover Image

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    B-cell–specific conditional expression of Myd88p.L252P (the murine orthologue of the human p.L265P point mutation) in combination with overexpression of BCL2 in B cells leads to the emergence of activated B cell diffuse large B-cell lymphoma in mice. The developing lymphomas stain positive for Cd138, as it is shown in this immunohistochemical staining of a heavily infiltrated liver. See the article by Knittel et al on page 2732.

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