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Journal Articles

Integrative Analysis of 1001 Diffuse Large B Cell Lymphoma Identifies Novel Oncogenic Roles for Rhoa

Jenny Zhang, BSc, Anupama Reddy, PhD, Nicholas Davis, BSc, Andrea Moffitt, PhD, Cassandra Love, Alexander Waldrop, PhD, Sirpa Leppa, MD, Annika Pasanen, MD, Leo Meriranta, MS, Marja-Liisa Karjalainen-Lindsberg, Peter H. Norgaard, MDPhD, Mette Ø Pedersen, MD, Anne Ortved Gang, Estrid Hogdall, PhD, Tayla Heavican, Waseem Lone, PhD, Javeed Iqbal, MSc, PhD, Guojie Li, PhD, So Young Kim, PhD, Jane Healy, MD PhD, Kristy L. Richards, MD PhD, Yuri Fedoriw, MD, Leon Bernal-Mizrachi, MD, Jean L. Koff, MD, Ashley D. Staton, MD, Christopher Flowers, MD, Ora Paltiel-Clarfield, Neta Goldschmidt, MD, Maria Calaminici, MD PhD, Andrew James Clear, BSc, John G. Gribben, MDDSc FMedSci, Evelyn Nguyen, Magdalena Czader, MD PhD, Sarah L. Ondrejka, MD, Angela Collie, MD PhD, Eric D. Hsi, MD, Eric Tse, MBBS, PhD FRCP, FRCPath, Rex Au-Yeung, Yok-Lam Kwong, Gopesh Srivastava, William Choi, MBBS,MRCP, Andrew M Evens, DO,MSc, Monika Pilichowska, MD PhD, Manju Sengar, MD DM, Nishitha Reddy, MD MSCI, MBBS, Shaoying Li, MD, Amy Chadburn, MD, Leo I. Gordon, MD, Elaine S. Jaffe, MD, Rachel Rempel, Tiffany Tzeng, Tushar Dave, Lanie Happ, Deepthi Rajagopalan, Jyotishka Datta, David Dunson, Sandeep Dave, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 37.
https://doi.org/10.1182/blood.V130.Suppl_1.37.37
Published: 2017
Journal Articles

Integrative Genetic and Clinical Analysis through Whole Exome Sequencing in 1001 Diffuse Large B Cell Lymphoma (DLBCL) Patients Reveals Novel Disease Drivers and Risk Groups

Jenny Zhang, Anupama Reddy, Cassandra Love, Andrea B. Moffitt, Deepthi Rajagopalan, Sirpa Leppä, Annika Pasanen, MD PhD, Leo Meriranta, MS, Marja-Liisa Karjalainen-Lindsberg, Peter H Norgaard, MD PhD, Mette Pederson, Anne Ortved Gang, Estrid Hogdall, Kristy L. Richards, PhD MD, Yuri D. Fedoriw, MD, Leon Bernal-Mizrachi, MD, Jean L. Koff, MD, Ashley D. Staton, MD, Christopher Flowers, MDMS, Ora Paltiel-Clarfield, Neta Goldschmidt, MD, Maria Calaminici, Andrew James Clear, John Gribben, Evelyn Nguyen, Magdalena Czader, MD PhD, Sarah Lynn Ondrejka, DO, Angela Collie, MD PhD, Eric D Hsi, MD, Rex au-Yeung, Kwong Yok-Lam, Wai Lap Choi, MD, Gopesh Srivastava, Andrew M Evens, DO, MSc, FACP, Monika Pilichowska, MD PhD, Manju Sengar, Nishitha Reddy, MD MSCI, MBBS, Shaoying Li, MD, Elaine S. Jaffe, MD, Tiffany Tzeng, Jyotishka Datta, David Dunson, Sandeep Dave, MD
Journal: Blood
Blood (2016) 128 (22): 1087.
https://doi.org/10.1182/blood.V128.22.1087.1087
Published: 2016
Journal Articles

GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo

Jane A. Healy, Adrienne Nugent, Rachel E. Rempel, Andrea B. Moffitt, Nicholas S. Davis, Xiaoyu Jiang, Jennifer R. Shingleton, Jenny Zhang, Cassandra Love, Jyotishka Datta, Matthew E. McKinney, Tiffany J. Tzeng, Nina Wettschureck, Stefan Offermanns, Katelyn A. Walzer, Jen-Tsan Chi, Suhail A. K. Rasheed, Patrick J. Casey, Izidore S. Lossos, Sandeep S. Dave
Journal: Blood
Blood (2016) 127 (22): 2723–2731.
https://doi.org/10.1182/blood-2015-07-659938
Published: 2016
Includes: Supplemental data
Journal Articles

Recurrent Mutations in Focal Adhesion Genes Including the RhoA Signaling Axis Are a Defining Feature of Germinal Center (GC) Derived B Cell Lymphomas and Promote Aberrant Migration and Cellular Adhesion within the GC Niche

Jane Healy, MD PhD, Rachel E Rempel, PhD, Andrea B. Moffitt, Nicholas Davis, Jenny Zhang, Cassandra Love, Jennifer R Shingleton, PhD, Sandeep Dave, MD
Journal: Blood
Blood (2015) 126 (23): 558.
https://doi.org/10.1182/blood.V126.23.558.558
Published: 2015
Journal Articles

Dendritic Cell Vaccine Treatment for B-Cell Non-Hodgkin Lymphoma: Clinical Trial in Progress

Yi Lin, MDPhD, Thomas Atwell, MD, Adam Weisbrod, MD, Mary Maas, Adam S. Armstrong, Michael Deeds, Peggy A Bulur, Michael Gustafson, PhD, Zhe (Jenny) Zhang, PhD, Stefan Cordes, MD PhD, Luis F. Porrata, MD, Svetomir N. Markovic, MD, PhD, Patrick B. Johnston, MD PhD, Ivana N. Micallef, MD, David J. Inwards, MD, Joseph P. Colgan, MD, Stephen M. Ansell, MD PhD, Dennis A. Gastineau, MD, Allan B Dietz, PhD, Thomas E. Witzig, MD
Journal: Blood
Blood (2014) 124 (21): 4474.
https://doi.org/10.1182/blood.V124.21.4474.4474
Published: 2014
Journal Articles

The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells

Jenny Zhang, Dereje Jima, Andrea B. Moffitt, Qingquan Liu, Magdalena Czader, Eric D. Hsi, Yuri Fedoriw, Cherie H. Dunphy, Kristy L. Richards, Javed I. Gill, Zhen Sun, Cassandra Love, Paula Scotland, Eric Lock, Shawn Levy, David S. Hsu, David Dunson, Sandeep S. Dave
Journal: Blood
Blood (2014) 123 (19): 2988–2996.
https://doi.org/10.1182/blood-2013-07-517177
Published: 2014
Includes: Supplemental data
Journal Articles

Whole Genome and Exome Sequencing Defines The Genetic Landscape Of Hepatosplenic T-Cell Lymphoma

Paula Scotland, PhD, Philippe Gaulard, MD, Cassandra L Love, MS, Virginie Fataccioli, PhD, Marion Travert, Laurence De Leval, Dennis D. Weisenburger, MD, Magdalena Czader, MD, PhD, Mayur Parihar, Reena Nair, MD, Manju Sengar, MD, DM, Anne W Beaven, MD, Jennifer H. Crow, MD, Rodney R. Miles, MD, PhD, Leo I. Gordon, MD, Amy Chadburn, M.D., Andrew M Evens, DO, MSc, Javed Gill, MD, Yuri D. Fedoriw, MD, Kristy L. Richards, MD PhD, Gopesh Srivastava, Ph.D, William W. L. Choi, MD, PhD, Christopher R. Flowers, MD, MS, Leon Bernal-Mizrachi, M.D., Karen P. Mann, MD, PhD, Kikkeri Naresh, Eric D. Hsi, MD, Pedro Horna, MD, Jianguo Tao, MD, PhD, Zhen Sun, MS, Kevin Long, Jenny Zhang, Sandeep Dave, MD
Journal: Blood
Blood (2013) 122 (21): 842.
https://doi.org/10.1182/blood.V122.21.842.842
Published: 2013
Journal Articles

Efficacy and Safety Of Fedratinib (SAR302503/TG101348) In Patients With Intermediate- Or High-Risk Myelofibrosis (MF), Post-Polycythemia Vera (PV) MF, Or Post-Essential Thrombocythemia (ET) MF Previously Treated With Ruxolitinib: Interim Results From a Phase II Study (JAKARTA-2)

Claire N Harrison, DM, FRCP, FRCPath, Nicolaas PM Schaap, MD, PhD, Sonja Zweegman, MD PhD, Eric Jourdan, MD PhD, Jean-Jacques Kiladjian, MD, PhD, Francisco Cervantes, MD, Dietger Niederwieser, MD, Jorge E. Cortes, MD, Francesco Passamonti, MD, Andreas Reiter, MD, Christian Recher, MD PhD, Konstanze Döhner, MD, Florian H Heidel, MD, Richard T. Silver, Elliott F Winton, MD, Vikas Gupta, MD, FRCP, FRCPath, Emilio Ojeda, MD, PhD, Heinz Gisslinger, MD, Alessandro M. Vannucchi, MD, Moshe Talpaz, MD, Jenny Zhang, MD PhD, Weiliang Shi, Ruben A. Mesa, MD
Journal: Blood
Blood (2013) 122 (21): 661.
https://doi.org/10.1182/blood.V122.21.661.661
Published: 2013
Journal Articles

The Genetic Landscape Of Mantle Cell Lymphoma and The Epigenetic Origins Of Lineage Specific Mutations

Jenny Zhang, Dereje Jima, MS, Qingquan Liu, PhD, Andrea Moffitt, Magdalena Czader, MD, PhD, Eric D. Hsi, MD, Yuri Fedirow, MD, Kristy L. Richards, MD PhD, Javed Gill, MD, Zhen Sun, MS, Cassandra L Love, MS, Paula B. Scotland, PhD, Eric Lock, PhD, Shawn Levy, PhD, David Dunson, PhD, Sandeep Dave, MD
Journal: Blood
Blood (2013) 122 (21): 347.
https://doi.org/10.1182/blood.V122.21.347.347
Published: 2013
Journal Articles

ID3 Is a Novel Tumor Suppressor Gene in Burkitt Lymphom

Cassandra L Love, Dereje Jima, MS, Zhen Sun, Rodney R. Miles, MD, PhD, Cherie H. Dunphy, MD, William W. L. Choi, MD, Wing Y Au, Gopesh Srivastava, Ph.D, Patricia Lugar, David A. Rizzieri, MD, Anand S. Lagoo, MD, PhD, Leon Bernal-Mizrachi, M.D., Karen P. Mann, MD, PhD, Christopher R. Flowers, MD, Kikkeri Naresh, Andrew M. Evens, DO, MSc, Amy Chadburn, MD, Leo I. Gordon, MD, Magdalena Czader, MD, PhD, Javed Gill, MD, Eric D. Hsi, MD, Jenny Zhang, Vladimir Grubor, PhD, Shawn Levy, Anjishnu Bunerjee, David Dunson, Guojie Li, Andrea Moffitt, Adrienne Greenough, Matthew S. McKinney, MD, Sandeep S. Dave, MD, MS
Journal: Blood
Blood (2012) 120 (21): 898.
https://doi.org/10.1182/blood.V120.21.898.898
Published: 2012
Journal Articles

Alterations in Metabolism and Mitochondrial Respiration Are Associated with Response to Targeted Inhibition of WNT Signaling in Lymphomas

Matthew S. McKinney, MD, Cassandra L Love, MS, Jenny Zhang, Sandeep S. Dave, MD, MS
Journal: Blood
Blood (2012) 120 (21): 778.
https://doi.org/10.1182/blood.V120.21.778.778
Published: 2012
Journal Articles

Pharmacogenetic Approaches Identify ANTXR1 As a Potential Mediator of Response to Therapeutic NF-κB Inhibition in Diffuse Large B Cell Lymphoma

Soham D. Puvvada, MD, Cassandra L Love, Vladimir Grubor, PhD, Jenny Zhang, Jason Smith, Sandeep S. Dave, MD
Journal: Blood
Blood (2011) 118 (21): 234.
https://doi.org/10.1182/blood.V118.21.234.234
Published: 2011
Journal Articles

Whole Genome and Exome Sequencing Reveals the Genetic Landscape of Burkitt Lymphoma

Cassandra L Love, Dereje Jima, MS, Jenny Zhang, Vladimir Grubor, PhD, Rodney R. Miles, MD, PhD, Cherie H. Dunphy, MD, Kristy L. Richards, PhD, MD, William W. L. Choi, MD, Wing Y Au, Gopesh Srivastava, Ph.D, Amy Chadburn, MD, Leo I. Gordon, MD, FACP, Andrew M. Evens, DO, MSc, Eric D. Hsi, MD, Magdalena Czader, MD, PhD, David A. Rizzieri, MD, Anand S. Lagoo, MD, PhD, Leon Bernal-Mizrachi, MD, Karen P. Mann, MD, PhD, Susan Sunay, Christopher R Flowers, MD, Kikkeri Naresh, Michael A. Thompson, MD, PhD, Javed Gill, MD, Sandeep S. Dave, MD
Journal: Blood
Blood (2011) 118 (21): 433.
https://doi.org/10.1182/blood.V118.21.433.433
Published: 2011
Journal Articles

Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs

e-blood
Dereje D. Jima, Jenny Zhang, Cassandra Jacobs, Kristy L. Richards, Cherie H. Dunphy, William W. L. Choi, Wing Yan Au, Gopesh Srivastava, Magdalena B. Czader, David A. Rizzieri, Anand S. Lagoo, Patricia L. Lugar, Karen P. Mann, Christopher R. Flowers, Leon Bernal-Mizrachi, Kikkeri N. Naresh, Andrew M. Evens, Leo I. Gordon, Micah Luftig, Daphne R. Friedman, J. Brice Weinberg, Michael A. Thompson, Javed I. Gill, Qingquan Liu, Tam How, Vladimir Grubor, Yuan Gao, Amee Patel, Han Wu, Jun Zhu, Gerard C. Blobe, Peter E. Lipsky, Amy Chadburn, Sandeep S. Dave, for the Hematologic Malignancies Research Consortium (HMRC)
Journal: Blood
Blood (2010) 116 (23): e118–e127.
https://doi.org/10.1182/blood-2010-05-285403
Published: 2010
Includes: Supplemental data
Journal Articles

A Randomized, Double-Blind, Placebo-Controlled Phase II Trial on the Efficacy, Safety and Tolerability of E5501 (AKR501) In Subjects with Chronic Immune Thrombocytopenia (ITP)

James B. Bussel, MD, Jenny Zhang, Shande Tang, Joe McIntosh, David J. Kuter, MD, DPhil
Journal: Blood
Blood (2010) 116 (21): 71.
https://doi.org/10.1182/blood.V116.21.71.71
Published: 2010
Journal Articles

Alternative Splicing Is a Major Mechanism of Gene Regulation In Diffuse Large B Cell Lymphoma

Cassandra L Jacobs, MS, Amee Patel, Dereje Jima, MS, Qingquan Liu, PhD, Adrienne Greenough, Jenny Zhang, Cherie Dunphy, MD, Kristy Richards, PhD, MD, Wai Choi, MBBS, MRCP, Gopesh Srivastava, Wing Y Au, Andrew M Evens, DO, MSc, Leo I Gordon, MD, FACP, Magdalena Czader, David A. Rizzieri, MD, Anand S. Lagoo, MD, PhD, Karen P. Mann, MD, PhD, Christopher R Flowers, MD, MS, Leon Bernal-Mizrachi, MD, Kikkeri Naresh, Micah Luftig, PhD, Amy Chadburn, MD, Eric Hsi, MD, Michael A. Thompson, MD, PhD, Javed Gill, MD, Sandeep Dave, MD
Journal: Blood
Blood (2010) 116 (21): 803.
https://doi.org/10.1182/blood.V116.21.803.803
Published: 2010
Journal Articles

Efficacy, Safety and Tolerability of E5501 (AKR501) In a 6-Month Extension Study In Subjects with Chronic Immune Thrombocytopenia (ITP).

James B. Bussel, MD, Jenny Zhang, Shande Tang, Joe McIntosh, David J. Kuter, MD, DPhil
Journal: Blood
Blood (2010) 116 (21): 3695.
https://doi.org/10.1182/blood.V116.21.3695.3695
Published: 2010
Journal Articles

A Comprehensive Identification of the Microrna Transcriptome and Its Application in B Cell Malignancies.

Cassandra L. Jacobs, MS, Dereje D Jima, MS, Jenny Zhang, Cherie Dunphy, Kristy L. Richards, PhD, MD, William W.L. Choi, MD, Gopesh Srivastava, Andrew M Evens, MSc, DO, Leo I. Gordon, MD, Magdalena Czader, MD, PhD, David A Rizzieri, Anand S. Lagoo, MD, PhD, Karen P. Mann, MD, PhD, Christopher R. Flowers, MD, Kikkeri Naresh, Micah Luftig, Daphne R Friedman, MD, J. Brice Weinberg, MD, Michael A. Thompson, MD, PhD, Javed Gill, MD, Brad S Kahl, Amy Chadburn, MD, Sandeep Dave, MD
Journal: Blood
Blood (2009) 114 (22): 2403.
https://doi.org/10.1182/blood.V114.22.2403.2403
Published: 2009
Journal Articles

Molecular Profiling Identifies Plasmablasts as the Cells of Origin of Activated Diffuse Large B Cell Lymphoma.

Cassandra L. Jacobs, MS, Patricia L. Lugar, Qingquan Liu, Jenny Zhang, Peter Lipsky, MD, Sandeep Dave, MD
Journal: Blood
Blood (2009) 114 (22): 621.
https://doi.org/10.1182/blood.V114.22.621.621
Published: 2009
Journal Articles

Patterns of microRNA expression characterize stages of human B-cell differentiation

Jenny Zhang, Dereje D. Jima, Cassandra Jacobs, Randy Fischer, Eva Gottwein, Grace Huang, Patricia L. Lugar, Anand S. Lagoo, David A. Rizzieri, Daphne R. Friedman, J. Brice Weinberg, Peter E. Lipsky, Sandeep S. Dave
Journal: Blood
Blood (2009) 113 (19): 4586–4594.
https://doi.org/10.1182/blood-2008-09-178186
Published: 2009
Includes: Supplemental data