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Journal Articles

Proteostasis disruption in inherited bone marrow failure syndromes

Helena Yu, Robert A. J. Signer

Blood (2025) 146 (3): 304–317.

https://doi.org/10.1182/blood.2024024956

Published: 2025

Journal Articles

An unbiased genomewide screen uncovers 7 genes that drive hematopoietic stem cell fate from mouse embryonic stem cells

Luis G. Palma, Gayathri M. Kartha, Maria Maqueda, Mercedes Barrero, Eric Canton, Arnau Iglesias, Jessica González, Patricia Herrero-Molinero, Raúl Torres-Ruiz, Bernhard Payer, Clara Bueno, Pablo Menéndez, Lluis Espinosa, Anna Bigas

Blood (2025) 146 (3): 328–340.

https://doi.org/10.1182/blood.2024027742

Published: 2025

Includes: Supplemental data

Journal Articles

When increased bone marrow blasts may not mean malignancy

Carlo Zaninetti, Alessandro Pecci

Blood (2025) 146 (2): 143–144.

https://doi.org/10.1182/blood.2025029542

Published: 2025

Journal Articles

ANKRD26-related thrombocytopenia 2 with a baseline increase in blasts: implications for clinical surveillance

Lara Wahlster, Lucy A. Godley, Jason X. Cheng, Michael W. Drazer, Christopher R. Reilly, Geraldine S. Pinkus, Jared H. Rowe, Nina Weichert-Leahey, R. Grant Rowe, Lev Gorfinkel, Karyn Brundige, Franziska Wachter, Luana Messa, Alan D. Michelson, Alan B. Cantor, Akiko Shimamura, Jacob R. Bledsoe

Blood (2025) 146 (2): 254–259.

https://doi.org/10.1182/blood.2024027368

Published: 2025

Includes: Supplemental data

Journal Articles

Loss of DCAF8 impairs hematopoietic stem cell function with cellular senescence via the DOCK11-CDC42 axis

Pengfei Xu, Xiuli Zhang, Donghe Li, Bo Jiao, Jiawei Nie, Yi Huang, Zhizhou Xia, Jiaoyang Li, Yuqing Dan, Xu Huang, Lei Yan, Rui Zhang, Wei Huang, Xinru Wang, Shiyu Ji, Yong Cang, Ruibao Ren, Ping Liu

Blood blood.2024027335.

https://doi.org/10.1182/blood.2024027335

Published: 2025

Includes: Supplemental data

Journal Articles

Tracking clusterin expression in hematopoietic stem cells reveals their heterogeneous composition across the life span

Blood (2025) 146 (1): 62–75.

https://doi.org/10.1182/blood.2024025776

Published: 2025

Includes: Supplemental data

Journal Articles

Pathogenesis of paroxysmal nocturnal hemoglobinuria

Lucio Luzzatto, Shinji Nakao

Blood (2025) 145 (26): 3077–3088.

https://doi.org/10.1182/blood.2024025975

Published: 2025

Journal Articles

Clinical and molecular features of immunodeficiency in patients with telomere biology disorders

Luiz Fernando B. Catto, Nidhi Aggarwal, Ruba N Shalhoub, Xiaoyang Ma, Ivana Darden, Tania Machado, Yue Zhang, Neelam Redekar, Natthakan Thongon, Simona Colla, Geraldine Aubert, Cynthia E. Dunbar, Colin O. Wu, Neal S. Young, Bhavisha A. Patel, Fernanda Gutierrez-Rodrigues, Emma M Groarke

Blood blood.2024026735.

https://doi.org/10.1182/blood.2024026735

Published: 2025

Includes: Supplemental data

Journal Articles

cMPL-based purification and depletion of human hematopoietic stem cells: implications for pretransplant conditioning

Daisuke Araki, So Gun Hong, Nathaniel Linde, Bryan Fisk, Neelam Redekar, Christi Salisbury-Ruf, Allen Krouse, Theresa Engels, Justin Golomb, Pradeep Dagur, Sumith R. Panicker, Yogendra Kanthi, Diogo M. Magnani, Zhirui Wang, Andre Larochelle

Blood (2025) 145 (25): 2978–2991.

https://doi.org/10.1182/blood.2024024636

Published: 2025

Includes: Supplemental data

Journal Articles

NOTCH1 dimeric signaling is essential for T-cell leukemogenesis and leukemia maintenance

Francesco Tamiro, Costanzo Padovano, Elisabetta De Santis, Serena Di Iasio, Delia Francesca Sansico, Valentina Canistro, Mattia Colucci, Chiara Di Nunzio, Gaja Bruno, Kashish Doshi, Angela Totaro, Eric Gu, Michele Santodirocco, Andrew P. Weng, Vincenzo Giambra

Blood (2025) 145 (24): 2887–2902.

https://doi.org/10.1182/blood.2024027020

Published: 2025

Includes: Supplemental data

Journal Articles

Correlates and Consequences of Clonal Hematopoiesis Expansion Rate: A 16-Year Longitudinal Study of 6976 Women

Blood blood.2025028417.

https://doi.org/10.1182/blood.2025028417

Published: 2025

Includes: Supplemental data

Journal Articles

An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesis

Justin Loke, Peter Geon Kim, Thuy T.P. Nguyen, Meaghan Boileau, Marie McConkey, Aidan P Miller, Wesley Shin, Christopher B Hergott, Maria Ericsson, Anja Nordstrom, Paula Montero-Llopis, Scott A. Armstrong, Joseph D. Mancias, Benjamin L Ebert

Blood blood.2024028033.

https://doi.org/10.1182/blood.2024028033

Published: 2025

Includes: Supplemental data

Journal Articles

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

Blood (2025) 145 (23): 2685–2700.

https://doi.org/10.1182/blood.2024027270

Published: 2025

Includes: Supplemental data

Journal Articles

One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying them

Ainsley V. C. Knox, Lauren Y. Cominsky, Di Sun, Emylette Cruz Cabrera, Brian E. Nolan, Edann Ofray, Elisa Benetti, Camilla Visconti, Federica Barzaghi, Sergio D. Rosenzweig, Monica G. Lawrence, Kathleen E. Sullivan, Samuel Yoon, Suzanna Rachimi, Nurcicek Padem, Erin Conboy, Maja Stojanovic, Gordana Petrovic, Srdjan Pasic, Joseph Church, Ronald M. Ferdman, Fabio Candotti, Tiphaine Arlabosse, Katerina Theodoropoulou, Cullen M. Dutmer, László Maródi, Gabriella Szücs, Arnon Broides, Amit Nahum, Jacov Levy, Kaisa Kettunen, Ravindra Daddali, Mikko Seppänen, Markku Vänttinen, Timi Martelius, Juha Grönholm, Matilde Peri, Chiara Azzari, Silvia Ricci, Samar Ojaimi, Emily S. J. Edwards, Menno C. van Zelm, Jinqiao Sun, Hassan Abolhassani, Qiang Pan-Hammarström, Hakon Hakonarson, Daniel Mayr, Kaan Boztug, Bertrand Boisson, Jean-Laurent Casanova, Carole Le Coz, Gregory M. K. Poon, Neil Romberg

Blood (2025) 145 (22): 2549–2560.

https://doi.org/10.1182/blood.2024026683

Published: 2025

Includes: Supplemental data

Journal Articles

PERK Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation

Manxi Zheng, Qinlu Peng, Erin M Kropp, Zhejuan Shen, Suxuan Liu, Zhengyou Yin, Sho Matono, Takao Iwawaki, Xiang Wang, Ken Inoki, Yang Mei, Qing Li, Lu Liu

Blood blood.2024027846.

https://doi.org/10.1182/blood.2024027846

Published: 2025

Includes: Supplemental data

Journal Articles

Advances in RNA editing in hematopoiesis and associated malignancies

Shuangshuang Pu, Tao Cheng, Hui Cheng

Blood (2025) 145 (21): 2424–2438.

https://doi.org/10.1182/blood.2024027379

Published: 2025

Journal Articles

Clonal hematopoiesis landscape in frequent blood donors

Blood (2025) 145 (21): 2411–2423.

https://doi.org/10.1182/blood.2024027999

Published: 2025

Includes: Supplemental data

Journal Articles

Lymphoid malignancies in patients with Shwachman-Diamond syndrome

Helen D. Reed, Hyunwoo Do, Edie Weller, Marian H. Harris, Christopher R. Reilly, Harrison K. Tsai, Jason E. Farrar, Bonnie W. Lau, Lauren Pommert, Christopher Gamper, Ian Atkinson, Katherine Coyne, Margret Joos, Sara Loveless, Sarah Steltz, Leah Cheng, Maggie Malsch, Kasiani Myers, Akiko Shimamura

Blood (2025) 145 (21): 2528–2532.

https://doi.org/10.1182/blood.2024026507

Published: 2025

Journal Articles

A new severe congenital neutropenia syndrome associated with autosomal recessive COPZ1 mutations

Blood (2025) 145 (20): 2317–2335.

https://doi.org/10.1182/blood.2023022576

Published: 2025

Includes: Supplemental data

Journal Articles

FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells

Blood (2025) 145 (20): 2361–2373.

https://doi.org/10.1182/blood.2024025886

Published: 2025

Includes: Supplemental data

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Proteostasis disruption in inherited bone marrow failure syndromes

An unbiased genomewide screen uncovers 7 genes that drive hematopoietic stem cell fate from mouse embryonic stem cells

When increased bone marrow blasts may not mean malignancy

ANKRD26-related thrombocytopenia 2 with a baseline increase in blasts: implications for clinical surveillance

Loss of DCAF8 impairs hematopoietic stem cell function with cellular senescence via the DOCK11-CDC42 axis

Tracking clusterin expression in hematopoietic stem cells reveals their heterogeneous composition across the life span

Pathogenesis of paroxysmal nocturnal hemoglobinuria

Clinical and molecular features of immunodeficiency in patients with telomere biology disorders

cMPL-based purification and depletion of human hematopoietic stem cells: implications for pretransplant conditioning

NOTCH1 dimeric signaling is essential for T-cell leukemogenesis and leukemia maintenance

Correlates and Consequences of Clonal Hematopoiesis Expansion Rate: A 16-Year Longitudinal Study of 6976 Women

An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesis

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying them

PERK Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation

Advances in RNA editing in hematopoiesis and associated malignancies

Clonal hematopoiesis landscape in frequent blood donors

Lymphoid malignancies in patients with Shwachman-Diamond syndrome

A new severe congenital neutropenia syndrome associated with autosomal recessive COPZ1 mutations

FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells

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