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Dennis M. Bonal
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Journal Articles

HiJAKing the hematopoietic system: a low-frequency JAK2V617F clone drives myeloproliferative neoplasm pathology

Available to Purchase
Dennis M. Bonal, Alissa Oakes, Anna Chorzalska, Makayla Pardo, Max Petersen, Michael Y. Clarke, Seo-Ho Lee, Adam J. Olszewski, Diana O. Treaba, John L. Reagan, Mark Dooner, John Morgan, Paul Bertone, Ting C. Zhao, Wentian Yang, Corey E. Ventetuolo, Gabriela S. Hobbs, Joslyn Mills, Patrycja M. Dubielecka
Journal: Blood
Blood (2025) 146 (20): 2428–2442.
https://doi.org/10.1182/blood.2024027125
Published: 2025
Includes: Supplemental data
Journal Articles

LRP1 / SDC1 / TGM2/LGALS3 Stromal Signature Is Linked to Favorable Induction Chemotherapy Response in AML

Free
Seo-Ho Lee, Dennis M Bonal, Diana Olguta Treaba, Makayla R Pardo, Anna Dorota Chorzalska, John L. Reagan, Adam J. Olszewski, Patrycja M. Dubielecka
Journal: Blood
Blood (2024) 144 (Supplement 1): 5657.
https://doi.org/10.1182/blood-2024-207910
Published: 2024
Journal Articles

Deciphering the AML Niche: RNA Sequencing and Spatial Transcriptomics Reveal Diverse Transcriptomic Landscapes in Responders Vs. Non-Responders

Free
Makayla R Pardo, Dennis M Bonal, Seo-Ho Lee, Anna Dorota Chorzalska, Valeria Brown, John L. Reagan, Diana Olguta Treaba, Patrycja M. Dubielecka
Journal: Blood
Blood (2024) 144 (Supplement 1): 64.
https://doi.org/10.1182/blood-2024-208213
Published: 2024
Journal Articles

Engrafted JAK2V617F Clone Hijacks Resident Non-Mutated Hematopoietic System to Drive Myeloproliferative Neoplasm

Free
Dennis M Bonal, Anna Dorota Chorzalska, Alissa Oakes, Makayla R Pardo, Seo-Ho Lee, Michael Y Clarke, Max Petersen, Hyunju Oh, Valeria Brown, Diana Olguta Treaba, John L. Reagan, Adam J. Olszewski, Mark Dooner, John Morgan, Joslyn Mills, Paul Bertone, Patrycja M Dubielecka
Journal: Blood
Blood (2024) 144 (Supplement 1): 754.
https://doi.org/10.1182/blood-2024-208312
Published: 2024
Journal Articles

Sry-Box Transcription Factor 9 (SOX9)-Driven Mesenchymal Stromal Cell Differentiation Signature As a Determinant of Induction Chemotherapy Responsiveness in Acute Myeloid Leukemia Core Bone Marrow Biopsies

Free
Seo-Ho Lee, Dennis M Bonal, Diana Olguta Treaba, Anna Dorota Chorzalska, Makayla Pardo, John L. Reagan, Adam J Olszewski, Patrycja M. Dubielecka
Journal: Blood
Blood (2023) 142 (Supplement 1): 4299.
https://doi.org/10.1182/blood-2023-189679
Published: 2023
Journal Articles

Loss of Complement Factor I (Cfi) a Negative Regulator of Complement Cascade Activity Exacerbates JAK2V617F-Dependent Phenotype

Free
Alissa Oakes, Dennis M Bonal, Zoe Creane, Hyunju Oh, Anna Dorota Chorzalska, Brooke Sadler, John L. Reagan, Rabin Niroula, Adam J Olszewski, Gabriel Haller, Stephen Donnelly, Patrycja M Dubielecka
Journal: Blood
Blood (2023) 142 (Supplement 1): 3149.
https://doi.org/10.1182/blood-2023-189483
Published: 2023
Journal Articles

Dysfunctional Stromal Pathways Mark Early Changes within the Bone Marrow Microenvironment in JAK2 V617F-Driven Model of Myeloproliferative Neoplasm

Free
Dennis M Bonal, Anna Dorota Chorzalska, Alissa Oakes, Makayla Pardo, Zoe Creane, Seo-Ho Lee, Omonike Oyelola, John L. Reagan, Adam Olszewski, Rabin Niroula, Stephen Donnelly, Joslyn Mills, Paul Bertone, Patrycja M Dubielecka
Journal: Blood
Blood (2023) 142 (Supplement 1): 3150.
https://doi.org/10.1182/blood-2023-189298
Published: 2023
Journal Articles

Complement Factor I (CFI) Deficiency Is Linked to Alterations in Humoral Immunity and Accelerated Development of JAK2V617F-Dependent Phenotype

Free
Alissa Oakes, Anna D Chorzalska, Dennis M Bonal, John L Reagan, Patrycja M Dubielecka
Journal: Blood
Blood (2022) 140 (Supplement 1): 8721–8722.
https://doi.org/10.1182/blood-2022-170675
Published: 2022
Journal Articles

Successful Engraftment of Murine JAK2V617F MPN-like Disease into Unconditioned Mice

Free
Dennis M Bonal, Anna D Chorzalska, Alissa Oakes, Valeria Brown, John L Reagan, Seo-Ho Lee, Patrycja M Dubielecka
Journal: Blood
Blood (2022) 140 (Supplement 1): 12158–12159.
https://doi.org/10.1182/blood-2022-170611
Published: 2022
Journal Articles

Proximity Proteomics Identifies Network of Lipid Metabolism Regulators in JAK2 V617F Interactome

Free
Max Petersen, Anna D Chorzalska, Anaelena Rodriguez, Dennis M Bonal, Patrycja M Dubielecka
Journal: Blood
Blood (2022) 140 (Supplement 1): 2988–2989.
https://doi.org/10.1182/blood-2022-170368
Published: 2022
Journal Articles

Alterations in the Humoral Immunophenotype of Children with Sickle Cell Disease on Hydroxyurea

Free
Emily Vistica-Sampino, Anna D Chorzalska, Dennis M Bonal, John Morgan, Lisa Nguyen, Anaelena Rodriguez, Rishi Lulla, Patrycja M Dubielecka
Journal: Blood
Blood (2022) 140 (Supplement 1): 2523–2525.
https://doi.org/10.1182/blood-2022-170719
Published: 2022
Journal Articles

Whole Genome Sequencing Identifies a Recurrent Mutation in Complement Factor I ( CFI ) in Primary Myelofibrosis (PMF)

Free
Brooke Sadler, Anna D Chorzalska, Dennis M Bonal, Gabe Haller, Alissa Oakes, Max Petersen, Yuchen Liu, Adam Olszewski, John L Reagan, Pamela C Egan, Rabin Niroula, Diana O Treaba, Gabriela Hobbs, Stephen T. Oh, Jorge Di Paola, Joanna E Baxter, Patrycja M Dubielecka
Journal: Blood
Blood (2021) 138 (Supplement 1): 1472.
https://doi.org/10.1182/blood-2021-154281
Published: 2021
Journal Articles

Levels of Osteopontin ( SPP1 ), Osteonectin ( SPARC ) and Biglycan ( BGN ) in Acute Myeloid Leukemia Bone Marrow Biopsies Post-Induction Therapy Define the Status of Osteogenic Niche and Show Inverse Correlation with Therapeutic Response

Free
Diana O Treaba, MD, Dennis M Bonal, Anna D Chorzalska, PhD, Christoph Schorl, PhD, Kelsey Hopkins, John L Reagan, MD, Peter Rintels, MD, Peter J Quesenberry, MD, Patrycja M Dubielecka, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-142604
Published: 2020