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Journal Articles

Multisite 11-year experience of less-intensive vs intensive therapies in acute myeloid leukemia

Clinical Trials & Observations
Mohamed L. Sorror, Barry E. Storer, Amir T. Fathi, Andrew Brunner, Aaron T. Gerds, Mikkael A. Sekeres, Sudipto Mukherjee, Bruno C. Medeiros, Eunice S. Wang, Pankit Vachhani, Paul J. Shami, Esteban Peña, Mahmoud Elsawy, Kehinde Adekola, Selina Luger, Maria R. Baer, David Rizzieri, Tanya M. Wildes, Jamie Koprivnikar, Julie Smith, Mitchell Garrison, Kiarash Kojouri, Wendy Leisenring, Lynn Onstad, Jennifer E. Nyland, Pamela S. Becker, Jeannine S. McCune, Stephanie J. Lee, Brenda M. Sandmaier, Frederick R. Appelbaum, Elihu H. Estey
Journal: Blood
Blood (2021) 138 (5): 387–400.
https://doi.org/10.1182/blood.2020008812
Published: 2021
Includes: Supplemental data
Journal Articles

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Praveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova, Huiyoung Yun, Yotam Drier, Noori Sotudeh, Anna Rogers, Madhu M. Ouseph, Monica Nair, Sayalee Potdar, Randi Isenhart, Jake A. Kloeber, Tushara Vijaykumar, Leili Niu, Tiffaney Vincent, Guangwu Guo, Julia Frede, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, David T. Teachey, Andrew A. Lane, Daniel J. DeAngelo, Jon C. Aster, Bradley E. Bernstein, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2021) 137 (18): 2463–2480.
https://doi.org/10.1182/blood.2019004547
Published: 2021
Includes: Supplemental data
Journal Articles

Thromboembolism prophylaxis in adult patients with acute lymphoblastic leukemia treated in the GRAALL-2005 study

CME Clinical Trials & Observations
Corentin Orvain, Marie Balsat, Emmanuelle Tavernier, Jean-Pierre Marolleau, Thomas Pabst, Patrice Chevallier, Noémie de Gunzburg, Victoria Cacheux, Françoise Huguet, Sylvain Chantepie, Denis Caillot, Yves Chalandon, Jamilé Frayfer, Caroline Bonmati, Véronique Lheritier, Norbert Ifrah, Hervé Dombret, Nicolas Boissel, Mathilde Hunault-Berger
Journal: Blood
Blood (2020) 136 (3): 328–338.
https://doi.org/10.1182/blood.2020004919
Published: 2020
Includes: Supplemental data
Journal Articles

FLT3 inhibitors added to induction therapy induce deeper remissions

Clinical Trials & Observations
Mark Levis, Wenge Shi, Ken Chang, Christian Laing, Reinhold Pollner, Christopher Gocke, Emily Adams, Flora Berisha, Jelveh Lameh, Arnaud Lesegretain
Journal: Blood
Blood (2020) 135 (1): 75–78.
https://doi.org/10.1182/blood.2019002180
Published: 2020
Includes: Supplemental data
Journal Articles

Haploidentical Hematopoietic Stem Cell Transplantation May Improve Prognosis in Non-Infant Children with t(v;11q23)/MLL-Rearranged B-Acute Lymphoblastic Leukemia

Lu Bai, Yi-Fei Cheng, Ai-Dong Lu, Pan Suo, Yu Wang, Ying-Xi Zuo, Chen-Hua Yan, Jun Wu, Yue-Ping Jia, Yu-Qian Sun, Yu-Hong Chen, Huan Chen, Kai-yan Liu, Wei Han, Lan-Ping Xu, Jing-Bo Wang, Xiang-Feng Tang, Hui-Ren Chen, Le-Ping Zhang, Xiao-Jun Huang
Journal: Blood
Blood (2019) 134 (Supplement_1): 2049.
https://doi.org/10.1182/blood-2019-127704
Published: 2019
Journal Articles

Treatment of Refractory Acute Myeloid Leukemia and High-Grade Myelodysplastic Syndrome: Implications of Further Care at an Academic Center Versus Community Setting

Noam E. Kopmar, MD, Megan Othus, PhD, Kelda Gardner, PA-C, Carole M. Shaw, BA, Anna B. Halpern, MD, Bart L. Scott, MD, Paul C. Hendrie, MD PhD, Roland B. Walter, MDPhDMS, Pamela S. Becker, MD PhD, Elihu H. Estey, MD, Mary-Elizabeth M. Percival, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2214.
https://doi.org/10.1182/blood-2019-123315
Published: 2019
Journal Articles

Comparative Efficacy and Safety of Bortezomib, Thalidomide, and Dexamethasone (VTd) without and with Daratumumab (D-VTd) from Cassiopeia Versus Vtd from Pethema/GEM in Patients with Newly Diagnosed Multiple Myeloma Using Propensity Score Matching (PSM)

Philippe Moreau, MD, Cyrille Hulin, MD, Sonja Zweegman, MD PhD, Yannan Hu, PhD, Bart Heeg, PhD, Mahmoud Hashim, Carla de Boer, Veronique Vanquickelberghe, Tobias Kampfenkel, MD, Annette Lam, Sarah Cote, Pieter Sonneveld
Journal: Blood
Blood (2019) 134 (Supplement_1): 4740.
https://doi.org/10.1182/blood-2019-123491
Published: 2019
Journal Articles

Phase II Randomized Trial of Gilteritinib Vs Midostaurin in Newly Diagnosed FLT3 Mutated Acute Myeloid Leukemia (AML)

Selina M. Luger, MD FRCPC, Zhuoxin Sun, PhD, Sanam Loghavi, MD, Hillard M Lazarus, MD, Jacob M. Rowe, MB, BS, Martin S. Tallman, MD, Keith W. Pratz, MD, Mark Litzow, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1309.
https://doi.org/10.1182/blood-2019-128377
Published: 2019
Journal Articles

Targeting NMNAT1 in Acute Myeloid Leukemia

Xiangguo Shi, PhD, Daisuke Nakada, PhD, Ayumi Kitano, Rebecca Murdaugh, BS, Yu-Jung Tseng, BS,MS, Kevin Hoegenauer, Tianyuan Hu, PhD, Yajian Jiang, BS
Journal: Blood
Blood (2019) 134 (Supplement_1): 879.
https://doi.org/10.1182/blood-2019-132139
Published: 2019
Journal Articles

Post-Remission Treatment with Chemotherapy or Allogeneic Hematopoietic Stem Cell Transplantation (alloHSCT) in Adult Patients with High-Risk (HR) Philadelphia Chromosome-Negative (Ph-neg) Acute Lymphoblastic Leukemia (ALL) According to Their Minimal Residual Disease (MRD). Final Results of the Pethema ALL-HR-11 Trial

Josep-Maria Ribera, MD PhD, Mireia Morgades, M.Prob.S, Juana Ciudad, PhD, Pau Montesinos, MD PhD, Pere Barba, MD PhD, Irene García-Cadenas, María José Moreno, MD, Susana Vives, MD, Jordi Esteve, Cristina Gil, Silvia Monsalvo, MD, María Teresa Artola, MD, Jordi Ribera, PhD, Eulàlia Genescà, PhD, Mar Tormo, MD PhD, Marta Cervera, MD, Daniel Martínez-Carballeira, MD, Andrés Novo, MD, José González-Campos, MD, Beatriz Soria, MD, Arancha Bermúdez, MD, Aurelio López Martínez, MD, Santiago Mercadal, MD, Rosa Fernández-Martín, MD, Rosa Coll, MD, Josefina Serrano, Maria Luz Amigo, MD, Pilar Martínez-Sánchez, Juan-Miguel Bergua, MD, Alfons Serrano-Maestro, MD, Alberto Giménez Conca, MD, Susana Barrena, PhD, Isabel Granada, PhD, Evarist Feliu, MD PhD, Alberto Orfao, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 826.
https://doi.org/10.1182/blood-2019-123613
Published: 2019
Journal Articles

Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart® Protein, in Salvage Therapy for Primary Refractory and Early Relapsed Acute Myeloid Leukemia (AML) Patients

Geoffrey L. Uy, MD, Ibrahim Aldoss, MD, Matthew C Foster, MD, David A Sallman, MD, Kendra L. Sweet, MD, David A. Rizzieri, MD, Peter H. Sayre, MD PhD, Anjali S. Advani, MD, Ashkan Emadi, MD, Matthew J. Wieduwilt, MD PhD, Norbert Vey, MD PhD, Fabio Ciceri, MD, Matteo Giovanni Carrabba, MD, Tamara Moyo, MD PhD, Sarah E. Church, PhD, Michael P. Rettig, PhD, Martha L. Arellano, MD, John E. Godwin, MD, Bob Löwenberg, MD PhD, Gerwin Huls, MD PhD, Farhad Ravandi, MD, John Muth, MS, Kathy Tran, Mojca Jongen-Lavrencic, MD PhD, Erin Timmeny, Max S. Topp, MD, Stefania Paolini, MD PhD, Kuo Guo, MSc, Teia Curtis, Jian Zhao, PhD, Jayakumar Vadakekolathu, PhD, Jon M. Wigginton, MD, Ezio Bonvini, MD, Sergio Rutella, MDPhDFRCPath, Roland B. Walter, MD PhD MS, Jan K Davidson-Moncada, MD PhD, John F. DiPersio, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 733.
https://doi.org/10.1182/blood-2019-122073
Published: 2019
Journal Articles

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

Johanna D Erbani, Joshua Tay, PhD, Valerie Barbier, Masters, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Ingrid G Winkler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 907.
https://doi.org/10.1182/blood-2019-132233
Published: 2019
Journal Articles

Validation of the Genetically-Defined DLBCL Subtypes and Generation of a Parsimonious Probabilistic Classifier

Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Timothy Wood, Andrew Dunford, MS, Kirsty Wienand, PhD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 920.
https://doi.org/10.1182/blood-2019-131250
Published: 2019
Journal Articles

Efficacy and Safety of Azacitidine (AZA) in Combination with the Anti-PD-L1 Durvalumab (durva) for the Front-Line Treatment of Older Patients (pts) with Acute Myeloid Leukemia (AML) Who Are Unfit for Intensive Chemotherapy (IC) and Pts with Higher-Risk Myelodysplastic Syndromes (HR-MDS): Results from a Large, International, Randomized Phase 2 Study

Amer M. Zeidan, MBBS, MHS, James Cavenagh, Maria Teresa Voso, David Taussig, Mar Tormo, Isaac Boss, Wilbert B. Copeland, Vanessa E. Gray, Alessandro Previtali, Tim O'Connor, Shelonitda Rose, CL Beach, Lewis R. Silverman
Journal: Blood
Blood (2019) 134 (Supplement_1): 829.
https://doi.org/10.1182/blood-2019-122896
Published: 2019
Journal Articles

Curative Strategy (GEM-CESAR) for High-Risk Smoldering Myeloma (SMM): Carfilzomib, Lenalidomide and Dexamethasone (KRd) As Induction Followed By HDT-ASCT, Consolidation with Krd and Maintenance with Rd

Maria-Victoria Mateos, Joaquin Martinez-Lopez, MD PhD, Paula Rodriguez Otero, Veronica Gonzalez-Calle, Marta Sonia Gonzalez, MD, Albert Oriol, MD, Norma C. Gutierrez, MD PhD, Bruno Paiva, PhD, Rafael Ríos Tamayo, Laura Rosinol Dachs, Miguel Angel Alvarez, MD, Maria Jose Calasanz, PhD BSc, Joan Bargay, MD PhD, Ana Pilar Gonzalez, PhD, Adrián Alegre Amor, MD, Fernando Escalante, MD, Belén Iñigo, Noemi Puig, MD PhD, Javier De La Rubia, Ana Isabel Teruel, MDcal Doctor, Maria Teresa Cedena Romero, MD PhD, Felipe De Arriba, PhD, Luis Palomera, MD PhD, Miguel T Hernández, Javier Lopez Jimenez, MD, Jesús Martín, Aránzazu García Mateo, PhD, Enrique M. Ocio, Joan Bladé, MD, Juan Jose Lahuerta, MD PhD, Jesús San-Miguel
Journal: Blood
Blood (2019) 134 (Supplement_1): 781.
https://doi.org/10.1182/blood-2019-125204
Published: 2019
Journal Articles

Anti-CD19 CAR T Therapy Following Autologous HSCT May be Safe and Effective in Patients with Refractory Large B-Cell Lymphoma

Wei Liu, Wenyang Huang, Rui Lv, Shuhui Deng, MD, Shuhua Yi, MD, Lugui Qiu, MD PhD, Dehui Zou, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 784.
https://doi.org/10.1182/blood-2019-127659
Published: 2019
Journal Articles

Outcomes Following Early Relapse in Patients with Mantle Cell Lymphoma

David A. Bond, MD, Jeffrey M. Switchenko, PhD MS, Kami J. Maddocks, MD, Michael C. Churnetski, Subir Goyal, Krithika Shanmugasundaram, MD, Oscar Calzada, BS, Bhaskar Kolla, MBBS, Veronika Bachanova, MD PhD, James N. Gerson, MD, Stefan K. Barta, MD MRCP, MS, Yazeed Sawalha, MD, Brian T. Hill, MD, Peter Martin, FRCPC, MD MS, Max J. Gordon, MD, Alexey Danilov, MD PhD, Natalie S Grover, MD, Stephanie Mathews, MD, Madelyn Burkart, MD, Reem Karmali, MD, Nilanjan Ghosh, MD PhD, Steven I Park, MD, Narendranath Epperla, MDMS, Talha Badar, MD, Jin Guo, MD, Mehdi Hamadani, MD, Timothy S. Fenske, MD, Mary-Kate Malecek, MD, Brad S. Kahl, MD, Christopher R. Flowers, MD MS, Kristie A. Blum, MD, Jonathon B. Cohen, MDMS
Journal: Blood
Blood (2019) 134 (Supplement_1): 753.
https://doi.org/10.1182/blood-2019-128415
Published: 2019
Journal Articles

Daratumumab (DARA) Maintenance Therapy Improves Depth of Response and Results in Durable Progression-Free Survival (PFS) Following Dara Plus Cyclophosphamide, Bortezomib, and Dexamethasone (CyBorD) Induction Therapy in Multiple Myeloma (MM): Update of the Lyra Study

Robert M. Rifkin, MD, Jason M. Melear, MD, Edward Faber, DO, MS, William I. Bensinger, John M Burke, MD, Mohit Narang, MD, Don Stevens, MD, Sriya Gunawardena, Yana Lutska, PharmD, Keqin Qi, PhD, Jon Ukropec, PhD, Ming Qi, MD PhD, Thomas S. Lin, MD PhD, Habte A Yimer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 863.
https://doi.org/10.1182/blood-2019-122497
Published: 2019
Journal Articles

Validation of the Revised AML-Composite Model for the Prediction of Prognosis in Older Patients Receiving Intensive Induction Therapy

Corentin Orvain, Aline Tanguy-Schmidt, Sylvain Thepot, MD, Anne Bouvier, Benedicte Ribourtout, Franck Genevieve, Aurelien Giltat, Marion Champire, Adeline Chanson, Marielle Subileau, Damien Luque Paz, Valerie Ugo, Norbert Ifrah, Mathilde Hunault, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1310.
https://doi.org/10.1182/blood-2019-127351
Published: 2019
Journal Articles

Maintenance Rituximab Improves Outcomes in Mantle Cell Lymphoma Patients Who Respond to Induction Therapy with Bendamustine + Rituximab without Autologous Transplant

Brian T. Hill, MD, Jeffrey M. Switchenko, PhD MS, Peter Martin, FRCPC, MD MS, Michael C. Churnetski, Yazeed Sawalha, MD, Subir Goyal, Krithika Shanmugasundaram, MD, Oscar Calzada, BS, Bhaskar Kolla, MBBS, Veronika Bachanova, MD PhD, James N. Gerson, MD, Stefan K. Barta, MD MRCP, MS, Max J. Gordon, MD, Alexey Danilov, MD PhD, Natalie S Grover, MD, Stephanie Mathews, MD, Madelyn Burkart, MD, Reem Karmali, MD, Nilanjan Ghosh, MD PhD, Steven I Park, MD, Narendranath Epperla, MDMS, David A. Bond, MD, Talha Badar, MD, Kristie A. Blum, MD, Jin Guo, MD, Mehdi Hamadani, MD, Timothy S. Fenske, MD, Mary-Kate Malecek, MD, Brad S. Kahl, MD, Christopher R. Flowers, MD MS, Jonathon B. Cohen, MDMS
Journal: Blood
Blood (2019) 134 (Supplement_1): 1525.
https://doi.org/10.1182/blood-2019-129404
Published: 2019