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Journal Articles

Delays to Diagnosis of Peripheral T-Cell Lymphoma and Clinical Utility of Molecular Profiling: A UK Multicentre Real-World Study

Blood (2024) 144 (Supplement 1): 4445.

https://doi.org/10.1182/blood-2024-205820

Published: 2024

Journal Articles

Protein Tyrosine Phosphatase PRL2 Promotes MLL -Rearranged Acute Myeloid Leukemia Development through Inhibiting the p53 Pathway

Shiyu Xiao, Hongxia Chen, Michihiro Kobayashi, Yunpeng Bai, Sergio Barajas, Wenjie Cai, Zhong-Yin Zhang, Yan Liu

Blood (2024) 144 (Supplement 1): 4109.

https://doi.org/10.1182/blood-2024-198244

Published: 2024

Journal Articles

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Blood (2023) 141 (3): 244–259.

https://doi.org/10.1182/blood.2022016580

Published: 2023

Includes: Supplemental data

Journal Articles

The Burkitt Lymphoma International Prognostic Index (BL-IPI)

Adam J Olszewski, MD, Lasse H. Jakobsen, PhD, Graham P. Collins, MD DPhil, Kate Cwynarski, Veronika Bachanova, MD PhD, Kristie A. Blum, MD, Kirsten M Boughan, DO, Mark Bower, MD, Alessia Dalla Pria, MD, Alexey Danilov, MD, Kevin A. David, MD, Catherine Diefenbach, MD, Fredrik Ellin, MD PhD, Narendranath Epperla, MDMS, Umar Farooq, MD, Tatyana A. Feldman, MD, Alina S. Gerrie, MD MPH, Deepa Jagadeesh, MDMPH, Manali Kamdar, MD MD, Reem Karmali, MDMSc, Shireen Kassam, MBBS, FRCPath, PhD, Vaishalee P. Kenkre, MD, Nadia Khan, MD, Andreas Klein, MD, Izidore S. Lossos, MD, Matthew A. Lunning, DO, FACP, Peter Martin, FRCPC, MD MS, Nicolas Martinex-Calle, Silvia Montoto, MD, Seema Naik, MD, Neil Palmisiano, MDMS, David Peace, MD, Elizabeth H Phillips, MBBS, BSc, Tycel J. Phillips, MD, Craig A. Portell, MD, Nishitha Reddy, MD, Anna Santarsieri, MBBS, Maryam Sarraf Yazdy, MD, Knut B. Smeland, Scott E. Smith, MD PhD, Stephen D. Smith, MD, Suchitra Sundaram, MD, Parameswaran Venugopal, MD, Adam Zayac, MD, Xiao-Yin Zhang, PhD, Catherine Zhu, Chan Yoon Cheah, MBBS, Tarec Christoffer El-Galaly, Andrew M. Evens, DO,MMSc

Blood (2020) 136 (Supplement 1): 46–49.

https://doi.org/10.1182/blood-2020-134985

Published: 2020

Journal Articles

Chidamide, Decitabine, Cytarabine, Aclarubicin, and Granulocyte Colony-Stimulating Factor (CDCAG) in Adults with Relapsed/Refractory Acute Myeloid Leukemia: Final Results from a Phase 1/2 Study

Lixin Wang, PhD MD, Guofeng Chen, MD, Jianliang Shen, MD PhD, Jianmin Luo, Meiyun Fang, MD, Xudong Wei, MD, Yinghua Li, MD, Zhuogang Liu, MD, Yin Zhang, MD, Sujun Gao, PhD, Xin Wang, MD PhD, Xiaoning Gao, MD PhD, Wei Zhou, MD, Yigai Ma, MD, Hui Liu, MD, Xinquan Li, MD PhD, Linhua Yang, MD, Li Yu, MD PhD

Blood (2018) 132 (Supplement 1): 2707.

https://doi.org/10.1182/blood-2018-99-111761

Published: 2018

Journal Articles

PRL2 Phosphatase Is a Key Mediator of Oncogenic Cytokine Signaling in Leukemia Stem Cells

Michihiro Kobayashi, MD PhD, Yunpeng Bai, PhD, Sisi Chen, BS, Sarah C Nabinger, PhD, Chonghua Yao, MD, Zhong-Yin Zhang, PhD, Yan Liu, PhD

Blood (2016) 128 (22): 724.

https://doi.org/10.1182/blood.V128.22.724.724

Published: 2016

Journal Articles

ASXL1-Mutated Donor HSCs Evolved into FLT3-ITD Positive AML in the Unrelated Donor and FLT3-ITD Negative AML in the Recipient after Transplant

Zhongwen Liu, MD, Hongxing Liu, MD, Yanli Zhang, MD, Dai Kong, MD, Jie Shi, MD, Yin Zhang, MD, Meiying Wen, Yongping Song, MD PhD, Chunrong Tong, MD, Mingyi Chen, MD PhD, William J. Murphy, PhD, Kai Sun, MD PhD

Blood (2015) 126 (23): 5403.

https://doi.org/10.1182/blood.V126.23.5403.5403

Published: 2015

Journal Articles

PRL2 Phosphatase Regulate Early Stage T-Cell Development through Fine-Tuning SCF/Kit Signaling

Kobayashi Michihiro, MD PhD, Yunpeng Bai, PhD, Momoko Yoshimoto, MD PhD, Rui Gao, PhD, Chen Sisi, Yuanshu Dong, PhD, Zhon-Yin Zhang, PhD, Yan Liu, PhD

Blood (2014) 124 (21): 1569.

https://doi.org/10.1182/blood.V124.21.1569.1569

Published: 2014

Journal Articles

PRL2 Maintains Hematopoietic Stem and Progenitor Cells Through Regulating SCF/KIT Signaling

Michihiro Kobayashi, MD, PhD, Yuanshu Dong, Ph.D., Hao Yu, Ph.D., Yunpeng Bai, Sisi Chen, Rui Gao, PhD, Mervin C. Yoder, MD, Reuben Kapur, PhD, Zhong-Yin Zhang, PhD, Yan Liu, PhD

Blood (2013) 122 (21): 3674.

https://doi.org/10.1182/blood.V122.21.3674.3674

Published: 2013

Journal Articles

Effects of Small-Molecule Inhibitors of TNFR2 Signaling Pathways On TNF-Mediated Expansion of CD4+FoxP3+ Regulatory T Cells

Xueqiang Wu, MD, Yan Chen, MD, PhD, Chunsheng Han, Yiwen Gong, Dingfang Bu, MD, Yin Zhang, Junyan Xia, Qian Liu, PhD, Xue Chen, PhD, Yang Hu, PhD, Ping Zhu, MD

Blood (2012) 120 (21): 4722.

https://doi.org/10.1182/blood.V120.21.4722.4722

Published: 2012

Journal Articles

The Protein Tyrosine Phosphatase, Shp2, Positively Contributes to FLT3-ITD-Induced Malignant Disease in Vivo and Co-Localizes with Nuclear Phospho-STAT5 in FLT3-ITD-Expressing Leukemic Cells.

Sarah C Nabinger, PhD, Xing Jun Li, MD, PhD, Baskar Ramdas, Ph.D., Yantao He, PhD, Xian Zhang, Ph.D., Briana Richine, Joshua Bowling, Seiji Fukuda, MD, PhD, Shreevrat Goenka, Ph.D., Ziyue Liu, Ph.D., Gen-Sheng Feng, PhD, Menggang Yu, Ph.D., George Sandusky, MD, H. Scott Boswell, MD, Zhong-Yin Zhang, PhD, Reuben Kapur, PhD, Rebecca J. Chan, MD, PhD

Blood (2012) 120 (21): 2420.

https://doi.org/10.1182/blood.V120.21.2420.2420

Published: 2012

Journal Articles

Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT

Blood (2012) 120 (13): 2669–2678.

https://doi.org/10.1182/blood-2011-08-375873

Published: 2012

Includes: Supplemental data

Journal Articles

Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT

Roberto Negro, Stefania Gobessi, Pablo G. Longo, Yantao He, Zhong-Yin Zhang, Luca Laurenti, Dimitar G. Efremov

Blood (2012) 119 (26): 6278–6287.

https://doi.org/10.1182/blood-2012-01-403162

Published: 2012

Includes: Supplemental data

Journal Articles

Low Expression of RPS14 Accompanied with p53-Independent Over-Apoptosis in Myelodysplastic Syndromes Patients with 5q- Aberration

Lingyun Wu, Yin Zhang, Qi He, Qingxia Zhang, Chunkang Chang, Xiao Li, MD, PhD

Blood (2011) 118 (21): 5046.

https://doi.org/10.1182/blood.V118.21.5046.5046

Published: 2011

Journal Articles

Outcome Disparities In Waldenstrom's Macroglobulinemia: A SEER Database Analysis

Sikander Ailawadhi, MD, Dongyun Yang, PhD, Gaurav Patel, MSHA, Yin Zhang, MD, Ibrahim T. Aldoss, MBBS, Miriam Y. Kim, MD, Asher Chanan-Khan, MD

Blood (2011) 118 (21): 845.

https://doi.org/10.1182/blood.V118.21.845.845

Published: 2011

Journal Articles

KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML

Peilin Ma, MD, PhD, Raghuveer Mali, Ph.D., Li-Fan Zeng, PhD, Holly Martin, Baskar Ramdas, Ph.D., Yantao He, PhD, Emily Sims, Joydeep Ghosh, Ph.D, Sarah C Nabinger, Shuo Li, Veerendra Munugalavadla, PhD, Anindya Chatterjee, PhD, George Sandusky, MD, Andrew Craig, PhD, Kevin D. Bunting, PhD, Gen-Sheng Feng, Rebecca J. Chan, MD, PhD, Zhong-Yin Zhang, PhD, Reuben Kapur, PhD

Blood (2011) 118 (21): 868.

https://doi.org/10.1182/blood.V118.21.868.868

Published: 2011

Journal Articles

Targeting the Protein Phosphatase, Shp2, Reduces FLT3-ITD-Induced Hyperproliferation of Murine Hematopoietic Progenitors.

Sarah C Nabinger, Yantao He, Fuqin Yin, Xian Zhang, Linda Senbanjo, Seiji Fukuda, MD, PhD, Menggang Yu, Gen-Sheng Feng, Zhong-Yin Zhang, Reuben Kapur, PhD, Rebecca J. Chan, MD, PhD

Blood (2009) 114 (22): 827.

https://doi.org/10.1182/blood.V114.22.827.827

Published: 2009

Journal Articles

Eradication of Tumors in Pre-Clinical Models of Multiple Myeloma by Anti-CS1 Monoclonal Antibody HuLuc63: Mechanism of Action Studies.

Audie Rice, PhD, Myles Dillon, B.S., Anne van Abbema, M.S., Lynne Jesaitis, Ph.D, Melanie Wong, M.Sc., Stacey Lawson, B.S., Gao Liu, M.S., Yin Zhang, M.S., David Powers, PhD, Susan Rhodes, B.Sc., Ingrid Caras, PhD, Debbie Law, PhD, Daniel Afar, PhD

Blood (2006) 108 (11): 3503.

https://doi.org/10.1182/blood.V108.11.3503.3503

Published: 2006

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Delays to Diagnosis of Peripheral T-Cell Lymphoma and Clinical Utility of Molecular Profiling: A UK Multicentre Real-World Study

Protein Tyrosine Phosphatase PRL2 Promotes MLL -Rearranged Acute Myeloid Leukemia Development through Inhibiting the p53 Pathway

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

The Burkitt Lymphoma International Prognostic Index (BL-IPI)

Chidamide, Decitabine, Cytarabine, Aclarubicin, and Granulocyte Colony-Stimulating Factor (CDCAG) in Adults with Relapsed/Refractory Acute Myeloid Leukemia: Final Results from a Phase 1/2 Study

PRL2 Phosphatase Is a Key Mediator of Oncogenic Cytokine Signaling in Leukemia Stem Cells

ASXL1-Mutated Donor HSCs Evolved into FLT3-ITD Positive AML in the Unrelated Donor and FLT3-ITD Negative AML in the Recipient after Transplant

PRL2 Phosphatase Regulate Early Stage T-Cell Development through Fine-Tuning SCF/Kit Signaling

PRL2 Maintains Hematopoietic Stem and Progenitor Cells Through Regulating SCF/KIT Signaling

Effects of Small-Molecule Inhibitors of TNFR2 Signaling Pathways On TNF-Mediated Expansion of CD4+FoxP3+ Regulatory T Cells

The Protein Tyrosine Phosphatase, Shp2, Positively Contributes to FLT3-ITD-Induced Malignant Disease in Vivo and Co-Localizes with Nuclear Phospho-STAT5 in FLT3-ITD-Expressing Leukemic Cells.

Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT

Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT

Low Expression of RPS14 Accompanied with p53-Independent Over-Apoptosis in Myelodysplastic Syndromes Patients with 5q- Aberration

Outcome Disparities In Waldenstrom's Macroglobulinemia: A SEER Database Analysis

KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML

Targeting the Protein Phosphatase, Shp2, Reduces FLT3-ITD-Induced Hyperproliferation of Murine Hematopoietic Progenitors.

Eradication of Tumors in Pre-Clinical Models of Multiple Myeloma by Anti-CS1 Monoclonal Antibody HuLuc63: Mechanism of Action Studies.

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