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Journal Articles

CRISPR/Cas9 Library Screens Identified Atp2a2 As an In Vivo Specific Tumor Suppressor in Myeloid Neoplasms

Ruka Shimura, Moe Tamura, Keita Yamamoto, Kohei Iida, Shuhei Asada, Emi Sugimoto, E. Christine Pietsch, Barbara A. Weir, Ramona Crescenzo, Glenn S. Cowley, Ricardo M. Attar, Ulrike Philippar, Satoshi Yamasaki, Taisei Hirouchi, Kaoru Uchimaru, Toshio Kitamura, Susumu Goyama
Journal: Blood
Blood (2024) 144 (Supplement 1): 949.
https://doi.org/10.1182/blood-2024-206816
Published: 2024
Journal Articles

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A - and NPM1 -altered leukemias

Min Chul Kwon, Jan Willem Thuring, Olivier Querolle, Xuedong Dai, Tinne Verhulst, Vineet Pande, Ann Marien, Dries Goffin, Daniela V. Wenge, Hong Yue, Jevon A. Cutler, Cyrus Jin, Florian Perner, Shanna M. Hogeling, Paul L. Shaffer, Frank Jacobs, Petra Vinken, Wei Cai, Vikki Keersmaekers, Filmon Eyassu, Balpreet Bhogal, Karin Verstraeten, Sara El Ashkar, Jennifer A. Perry, Prathiba Jayaguru, Laura Barreyro, Anna Kuchnio, Nicolas Darville, Daniel Krosky, Gregor Urbanietz, Bie Verbist, James P. Edwards, Glenn S. Cowley, Robert Kirkpatrick, Ruth Steele, Lucille Ferrante, Christina Guttke, Nikki Daskalakis, E. Christine Pietsch, David M. Wilson, Ricardo Attar, Yusri Elsayed, Eric S. Fischer, Jan Jacob Schuringa, Scott A. Armstrong, Kathryn Packman, Ulrike Philippar
Journal: Blood
Blood (2024) 144 (11): 1206–1220.
https://doi.org/10.1182/blood.2023022480
Published: 2024
Includes: Supplemental data
Journal Articles

SETDB1 Suppresses Interferon Responses and NK Cell-Mediated Immunosurveillance Specifically in Monocytic AML

Yu-Hsuan Chang, Keita Yamamoto, Takeshi Fujino, Teh-Wei Wang, Emi Sugimoto, Wenyu Zhang, Tomohiro Yabushita, E. Christine Pietsch, Barbara A. Weir, Ramona Crescenzo, Glenn S. Cowley, Ricardo M. Attar, Ulrike Philippar, Yutaka Enomoto, Yoichi Imai, Toshio Kitamura, Susumu Goyama
Journal: Blood
Blood (2023) 142 (Supplement 1): 713.
https://doi.org/10.1182/blood-2023-177531
Published: 2023
Journal Articles

Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4 CRBN activity

Quinlan L. Sievers, Jessica A. Gasser, Glenn S. Cowley, Eric S. Fischer, Benjamin L. Ebert
Journal: Blood
Blood (2018) 132 (12): 1293–1303.
https://doi.org/10.1182/blood-2018-01-821769
Published: 2018
Includes: Supplemental data
Journal Articles

Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells

H Avraham, E Vannier, S Cowley, SX Jiang, S Chi, CA Dinarello, KM Zsebo, JE Groopman
Journal: Blood
Blood (1992) 79 (2): 365–371.
https://doi.org/10.1182/blood.V79.2.365.365
Published: 1992