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Journal Articles

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

Blood (2021) 137 (24): 3403–3415.

https://doi.org/10.1182/blood.2020009023

Published: 2021

Includes: Supplemental data

Journal Articles

High-Density Domain-Focused CRISPR Screens Reveal Epigenetic Regulators of Hox/Meis Gene Expression in Acute Myeloid Leukemia

Karina Barbosa, BSc, Anagha Deshpande, PhD, Ping Xiang, PhD, Bo-Rui Chen, PhD, Adam Brown, MSc, Neil Robertson, Younguk Sun, PhD, John Doench, PhD, Peter D Adams, PhD, R. Keith Humphries, MD PhD, Prashant Mali, PhD, Aniruddha J. Deshpande, PhD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-141412

Published: 2020

Journal Articles

Single Cell Profiling of DNMT3A-Mutant Progenitors Reveals LY86 As a Novel Pre-Leukemia Marker and Potential Therapeutic Target

Mira Jeong, PhD, Sangbae Kim, PhD, Yumei Li, PhD, Rui Chen, PhD, Premal Lulla, MBBS, Margaret Goodell, PhD

Blood (2019) 134 (Supplement_1): 2724.

https://doi.org/10.1182/blood-2019-123597

Published: 2019

Journal Articles

Genomic and Proteomic Profiling of AF10-Fusion Oncoproteins Reveal Mechanisms of Leukemogenesis and Actionable Targets

Bo-Rui Chen, PhD, Anagha Deshpande, PhD, Maria Kleppe, PhD, Narayana Yeddula, PhD, Sunnie Yoh, PhD, Scott A. Armstrong, MD PhD, Ross L. Levine, MD, Sumit Chanda, PhD, Aniruddha J. Deshpande, PhD

Blood (2018) 132 (Supplement 1): 544.

https://doi.org/10.1182/blood-2018-99-119210

Published: 2018

Journal Articles

Donor-derived MDS/AML in families with germline GATA2 mutation

Pallavi Galera, Amy P. Hsu, Weixin Wang, Stephenie Droll, Rui Chen, Jason R. Schwartz, Jeffery M. Klco, Sally Arai, Luke Maese, Christa Zerbe, Mark J. Parta, Neal S. Young, Steven M. Holland, Dennis D. Hickstein, Katherine R. Calvo

Blood (2018) 132 (18): 1994–1998.

https://doi.org/10.1182/blood-2018-07-861070

Published: 2018

Includes: Supplemental data

Journal Articles

Association Between Down-Regulation of EZH2 and Abnormal Karyotype, Response to Hypomethylation Treatment, and Patient Survival in Myelodysplastic Syndromes

Yue Wei, Monica Cabrero, MD, Yu Jia, Hong Zheng, Hui Yang, MD, PhD, Zhihong Fang, Zach Bohannan, Rui Chen, PhD, Hui Wang, PhD, Simona Colla, Xia Wang, Guillermo Garcia-Manero, MD

Blood (2014) 124 (21): 3241.

https://doi.org/10.1182/blood.V124.21.3241.3241

Published: 2014

Journal Articles

Transcriptomic Evaluation of CD34+ Marrow Cells from Myelodysplastic Syndrome (MDS) Patients

Hogune Im, PhD, Varsha Rao, PhD, Kunju Joshi Sridhar, PhD, Rui Chen, PhD, George Mias, PhD, Yan Zhang, MD, Li Xiao, MD, Michael P Snyder, PhD, Peter L. Greenberg, MD

Blood (2014) 124 (21): 1894.

https://doi.org/10.1182/blood.V124.21.1894.1894

Published: 2014

Journal Articles

TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients

Rafael Bejar, Allegra Lord, Kristen Stevenson, Michal Bar-Natan, Albert Pérez-Ladaga, Jacques Zaneveld, Hui Wang, Bennett Caughey, Petar Stojanov, Gad Getz, Guillermo Garcia-Manero, Hagop Kantarjian, Rui Chen, Richard M. Stone, Donna Neuberg, David P. Steensma, Benjamin L. Ebert

Blood (2014) 124 (17): 2705–2712.

https://doi.org/10.1182/blood-2014-06-582809

Published: 2014

Includes: Supplemental data

Journal Articles

Assessment Of EZH2 Expression In CD34+ Bone Marrow Progenitor Cells Of Patients Of Myelodysplastic Syndromes (MDS)

Yue Wei, PhD, Yu Jia, Hong Zheng, Hui Yang, MD, PhD., Rui Chen, Ph.D., Hui Wang, Ph.D., Xia Wang, Guillermo Garcia-Manero, MD

Blood (2013) 122 (21): 2805.

https://doi.org/10.1182/blood.V122.21.2805.2805

Published: 2013

Journal Articles

Large Conserved Domains Of Low DNA Methylation Maintained By 5-Hydroxymethycytosine and Dnmt3a

Blood (2013) 122 (21): 2406.

https://doi.org/10.1182/blood.V122.21.2406.2406

Published: 2013

Journal Articles

Long Non-Coding RNAs Control Hematopoietic Stem Cells (HSC) Function

Min Luo, Ph.D., Mira Jeong, Ph.D., Deqiang Sun, Ph.D., Hyun-Jung Park, PhD, Liubin Yang, Hui Wang, Ph.D., Rui Chen, Ph.D., Gretchen Darlington, Ph.D., Wei Li, Ph.D., Margaret A. Goodell, PhD

Blood (2013) 122 (21): 48.

https://doi.org/10.1182/blood.V122.21.48.48

Published: 2013

Journal Articles

Phase I Study of Decitabine and Rapamycin in Relapsed/Refractory Acute Myelogenous Leukemia

Jane L. Liesveld, MD, Kristen O'Dwyer, MD, Michael W. Becker, MD, Deborah Mulford, MD, Alison Walker, MD, Rui Chen, PhD, Jeremy Bechelli, MS, Karen Rosell, BS, Craig T. Jordan, PhD, Mohammad Minhajuddin, PhD, Gordon L. Phillips, II, MD

Blood (2012) 120 (21): 3549.

https://doi.org/10.1182/blood.V120.21.3549.3549

Published: 2012

Journal Articles

Deregulation of TLR2-JMJD3 Innate Immunity Signaling, Including a Rare TLR2 SNP As a Potential Somatic Mutation, in Myelodysplastic Syndromes (MDS)

Yue Wei, PhD, Rui Chen, Sophie Dimicoli, MD, PhD, Carlos E. Bueso-Ramos, MD, PhD, Donna S. Neuberg, ScD, Sherry A. Pierce, RN, BS, Hui Yang, MD, PhD., Yu Jia, Hong Zheng, Zhihong Fang, Martin Nguyen, Michael Fernandez, Sa A. Wang, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2012) 120 (21): 1700.

https://doi.org/10.1182/blood.V120.21.1700.1700

Published: 2012

Journal Articles

Histone Alterations Are Associated with Hematopoietic Stem Cell (HSC) Differentiation and Aging

Min Luo, Ph.D., Mira Jeong, Ph.D., Deqiang Sun, Ph.D., Hui Wang, Ph.D., Rui Chen, Ph.D., Wei Li, Ph.D., Gretchen Darlington, Ph.D., Margaret A. Goodell, PhD

Blood (2012) 120 (21): 1188.

https://doi.org/10.1182/blood.V120.21.1188.1188

Published: 2012

Journal Articles

Detection of Recurrent Mutations by Pooled Targeted Next-Generation Sequencing in MDS Patients Prior to Treatment with Hypomethylating Agents or Stem Cell Transplantation

Rafael Bejar, MD, PhD, Kristen E. Stevenson, MS, Petar Stojanov, J. Eric Zaneveld, Michal Bar-Natan, Bennett Caughey, Hui Wang, Ph.D., Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, Corey Cutler, MD, MPH, FRCPC, Jerome Ritz, MD, Kristian Cibulskis, Gad Getz, PhD, David P. Steensma, MD, Richard M. Stone, MD, Rui Chen, Ph.D., Donna S. Neuberg, ScD, Benjamin L. Ebert, MD, PhD

Blood (2012) 120 (21): 311.

https://doi.org/10.1182/blood.V120.21.311.311

Published: 2012

Journal Articles

Dnmt3b Is Dispensable for Hematopoietic Stem Cell Differentiation, but Acts Synergistically with Dnmt3a to Control the Balance Between Self-Renewal and Differentiation

Allison Mayle, Grant Anthony Challen, PhD, Deqiang Sun, Ph.D., Mira Jeong, Ph.D., Min Luo, Ph.D., Rui Chen, Ph.D., Hui Wang, Ph.D., Wei Li, Ph.D., Margaret A. Goodell, PhD

Blood (2012) 120 (21): 848.

https://doi.org/10.1182/blood.V120.21.848.848

Published: 2012

Journal Articles

Toll-Like Receptor (TLR) Signaling Adaptor Protein MYD88 in Myelodysplastic Syndromes (MDS)

Sophie Dimicoli, MD, PhD, Yue Wei, PhD, Rui Chen, Carlos E. Bueso-Ramos, MD, PhD, Sherry A. Pierce, RN, BS, Hui Yang, MD, PhD., Yu Jia, Hong Zheng, Zhihong Fang, Irene ganan-Gomez, Martin Nguyen, Michael Fernandez, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2012) 120 (21): 556.

https://doi.org/10.1182/blood.V120.21.556.556

Published: 2012

Journal Articles

HSC Aging Epigenome: Widespread Alterations in DNA Methylation and Transcription.

Mira Jeong, Ph.D., Min Luo, Ph.D., Deqiang Sun, Ph.D., Gretchen Darlington, Ph.D., Rebecca Hannah, Ph.D., Berthold Gottgens, Ph.D., Hui Wang, Ph.D., Rui Chen, Ph.D., Wei Li, Ph.D., Margaret A. Goodell, PhD

Blood (2012) 120 (21): 2329.

https://doi.org/10.1182/blood.V120.21.2329.2329

Published: 2012

Journal Articles

Impact of Clinical Factors on Platelet Engraftments In Contemporary Stem Cell Transplantation.

Jane L. Liesveld, MD, Rui Chen, Joseph Pawlowski, Jessica Debolt, Michael Becker, Louis Constine, Gordon L. Phillips, II, MD, Ollivier Hyrien, Yuhchyau Chen

Blood (2010) 116 (21): 4522.

https://doi.org/10.1182/blood.V116.21.4522.4522

Published: 2010

Journal Articles

Blood CD34 Levels as a Predictor of Successful Peripheral Blood Stem Cell Mobilization In Consecutive Autologous Stem Cell Apheresis Patients From a Single Transplant Center

Sujatha Mogili, Rui Chen, Michael Becker, Faith Young, Gordon L. Phillips, II, MD, Sue Frauenhofer, Donna Cimbalo, Sean Czaja, Diane Nichols, Jane L. Liesveld, MD

Blood (2010) 116 (21): 4440.

https://doi.org/10.1182/blood.V116.21.4440.4440

Published: 2010

NARROW

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

High-Density Domain-Focused CRISPR Screens Reveal Epigenetic Regulators of Hox/Meis Gene Expression in Acute Myeloid Leukemia

Single Cell Profiling of DNMT3A-Mutant Progenitors Reveals LY86 As a Novel Pre-Leukemia Marker and Potential Therapeutic Target

Genomic and Proteomic Profiling of AF10-Fusion Oncoproteins Reveal Mechanisms of Leukemogenesis and Actionable Targets

Donor-derived MDS/AML in families with germline GATA2 mutation

Association Between Down-Regulation of EZH2 and Abnormal Karyotype, Response to Hypomethylation Treatment, and Patient Survival in Myelodysplastic Syndromes

Transcriptomic Evaluation of CD34+ Marrow Cells from Myelodysplastic Syndrome (MDS) Patients

TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients

Assessment Of EZH2 Expression In CD34+ Bone Marrow Progenitor Cells Of Patients Of Myelodysplastic Syndromes (MDS)

Large Conserved Domains Of Low DNA Methylation Maintained By 5-Hydroxymethycytosine and Dnmt3a

Long Non-Coding RNAs Control Hematopoietic Stem Cells (HSC) Function

Phase I Study of Decitabine and Rapamycin in Relapsed/Refractory Acute Myelogenous Leukemia

Deregulation of TLR2-JMJD3 Innate Immunity Signaling, Including a Rare TLR2 SNP As a Potential Somatic Mutation, in Myelodysplastic Syndromes (MDS)

Histone Alterations Are Associated with Hematopoietic Stem Cell (HSC) Differentiation and Aging

Detection of Recurrent Mutations by Pooled Targeted Next-Generation Sequencing in MDS Patients Prior to Treatment with Hypomethylating Agents or Stem Cell Transplantation

Dnmt3b Is Dispensable for Hematopoietic Stem Cell Differentiation, but Acts Synergistically with Dnmt3a to Control the Balance Between Self-Renewal and Differentiation

Toll-Like Receptor (TLR) Signaling Adaptor Protein MYD88 in Myelodysplastic Syndromes (MDS)

HSC Aging Epigenome: Widespread Alterations in DNA Methylation and Transcription.

Impact of Clinical Factors on Platelet Engraftments In Contemporary Stem Cell Transplantation.

Blood CD34 Levels as a Predictor of Successful Peripheral Blood Stem Cell Mobilization In Consecutive Autologous Stem Cell Apheresis Patients From a Single Transplant Center

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American Society of Hematology

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American Society of Hematology

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