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Journal Articles

Progression signature underlies clonal evolution and dissemination of multiple myeloma

Yu Jia Shen, Yuji Mishima, Jiantao Shi, Romanos Sklavenitis-Pistofidis, Robert A. Redd, Michele Moschetta, Salomon Manier, Aldo M. Roccaro, Antonio Sacco, Yu-Tzu Tai, Francois Mercier, Yawara Kawano, Nang Kham Su, Brianna Berrios, John G. Doench, David E. Root, Franziska Michor, David T. Scadden, Irene M. Ghobrial

Blood (2021) 137 (17): 2360–2372.

https://doi.org/10.1182/blood.2020005885

Published: 2021

Includes: Supplemental data

Journal Articles

Overexpression of Histone Demethylase KDM6B in the Hematopoietic Compartment Promotes the Effect of Innate Immune Activation and Results in Myelodysplastic Syndrome (MDS)-like Phenotype in Mice

Yue Wei, PhD, Guillermo Garcia-Manero, MD, Hong Zheng, Yu Jia, Naran Bao, Shan Jiang, Joseph David Khoury, MD, Caleb Class, Simona Colla, PhD, Carlos E. Bueso-Ramos, MD PhD

Blood (2017) 130 (Supplement 1): 50.

https://doi.org/10.1182/blood.V130.Suppl_1.50.50

Published: 2017

Journal Articles

Overexpression of KDM6B, an Epigenetic and Innate Immune Regulator, Results in Hematopoietic Alterations of Mice Including Changes in Hematopoietic Stem Cells

Yue Wei, PhD, Hong Zheng, Yu Jia, Naran Bao, Shan Jiang, Simona Colla, PhD, Carlos E Bueso-Ramos, MD PhD, Joseph D Khoury, MD, Zachary S. Bohannan, MA, Guillermo Garcia-Manero, MD

Blood (2016) 128 (22): 3149.

https://doi.org/10.1182/blood.V128.22.3149.3149

Published: 2016

Journal Articles

Pharmacological Inhibition of Histone Demethylase JMJD3 Reduces Leukemia Cell Survival and Represses Production of the Cytokine CCL2 in MDS/AML

Yue Wei, PhD, Yu Jia, Hong Zheng, Hui Yang, MD PhD, Zachary S. Bohannan, MA, John Lee, Chong Zhao, Carlos E. Bueso-Ramos, MD, Ali N. Chamseddine, MD, Guillermo Garcia-Manero, MD

Blood (2015) 126 (23): 5219.

https://doi.org/10.1182/blood.V126.23.5219.5219

Published: 2015

Journal Articles

Association Between Down-Regulation of EZH2 and Abnormal Karyotype, Response to Hypomethylation Treatment, and Patient Survival in Myelodysplastic Syndromes

Yue Wei, Monica Cabrero, MD, Yu Jia, Hong Zheng, Hui Yang, MD, PhD, Zhihong Fang, Zach Bohannan, Rui Chen, PhD, Hui Wang, PhD, Simona Colla, Xia Wang, Guillermo Garcia-Manero, MD

Blood (2014) 124 (21): 3241.

https://doi.org/10.1182/blood.V124.21.3241.3241

Published: 2014

Journal Articles

Association Between Downregulation of POT1 Expression and Chromosome 7 Deletion, Response to Hypomethylation Agent Treatment, and Patient Survival in Myelodysplastic Syndromes

Yue Wei, Amit Verma, MD, Monica Cabrero, MD, Yu Jia, Hong Zheng, Zhihong Fang, Yiting Yu, PhD, Simona Colla, Zach Bohannan, Teresa V. Bowman, PhD, Jacqueline Boultwood, PhD, Guillermo Garcia-Manero, MD

Blood (2014) 124 (21): 4663.

https://doi.org/10.1182/blood.V124.21.4663.4663

Published: 2014

Journal Articles

Down-Regulated Expression Of Protection Of Telomeres 1 (POT1) Gene In Bone Marrow Hematopoietic Progenitor Cell Compartment Has Prognostic Value In Myelodysplastic Syndromes (MDS)

Yue Wei, PhD, Yu Jia, Hong Zheng, Hui Yang, M.D., Ph.D., Zhihong Fang, Simona Colla, PhD, Guillermo Garcia-Manero, MD

Blood (2013) 122 (21): 1511.

https://doi.org/10.1182/blood.V122.21.1511.1511

Published: 2013

Journal Articles

Assessment Of EZH2 Expression In CD34+ Bone Marrow Progenitor Cells Of Patients Of Myelodysplastic Syndromes (MDS)

Yue Wei, PhD, Yu Jia, Hong Zheng, Hui Yang, MD, PhD., Rui Chen, Ph.D., Hui Wang, Ph.D., Xia Wang, Guillermo Garcia-Manero, MD

Blood (2013) 122 (21): 2805.

https://doi.org/10.1182/blood.V122.21.2805.2805

Published: 2013

Journal Articles

Low frequency of H3.3 mutations and upregulated DAXX expression in MDS

Youmna Attieh, Qi-Rong Geng, Courtney D. DiNardo, Hong Zheng, Yu Jia, Zhi-Hong Fang, Irene Gañán-Gómez, Hui Yang, Yue Wei, Hagop Kantarjian, Guillermo Garcia-Manero

Blood (2013) 121 (19): 4009–4011.

https://doi.org/10.1182/blood-2012-11-466714

Published: 2013

Journal Articles

Deregulation of TLR2-JMJD3 Innate Immunity Signaling, Including a Rare TLR2 SNP As a Potential Somatic Mutation, in Myelodysplastic Syndromes (MDS)

Yue Wei, PhD, Rui Chen, Sophie Dimicoli, MD, PhD, Carlos E. Bueso-Ramos, MD, PhD, Donna S. Neuberg, ScD, Sherry A. Pierce, RN, BS, Hui Yang, MD, PhD., Yu Jia, Hong Zheng, Zhihong Fang, Martin Nguyen, Michael Fernandez, Sa A. Wang, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2012) 120 (21): 1700.

https://doi.org/10.1182/blood.V120.21.1700.1700

Published: 2012

Journal Articles

Serum Amyloid Protein A 1 (hSAA1) Is Overexpressed in Myelodysplastic Syndromes and Potentially Mediates Toll-Like Receptor 2 Innate Immunity Signaling in CD34+ Hematopoietic Stem Cells

Yue Wei, PhD, Carlos E. Bueso-Ramos, MD, PhD, Hui Yang, MD, PhD., Yu Jia, Hong Zheng, Simona Colla, Martin Nguyen, Michael Fernandez, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2012) 120 (21): 1703.

https://doi.org/10.1182/blood.V120.21.1703.1703

Published: 2012

Journal Articles

Low Frequency of Molecular Alterations of H3.3-Atrx-Daxx Chromatin Remodeling Component Genes in Myelodysplastic Syndromes (MDS)

Youmna Attieh, Yue Wei, PhD, Hui Yang, MD, PhD., Yu Jia, Hong Zheng, Zhihong Fang, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2012) 120 (21): 3844.

https://doi.org/10.1182/blood.V120.21.3844.3844

Published: 2012

Journal Articles

Toll-Like Receptor (TLR) Signaling Adaptor Protein MYD88 in Myelodysplastic Syndromes (MDS)

Sophie Dimicoli, MD, PhD, Yue Wei, PhD, Rui Chen, Carlos E. Bueso-Ramos, MD, PhD, Sherry A. Pierce, RN, BS, Hui Yang, MD, PhD., Yu Jia, Hong Zheng, Zhihong Fang, Irene ganan-Gomez, Martin Nguyen, Michael Fernandez, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2012) 120 (21): 556.

https://doi.org/10.1182/blood.V120.21.556.556

Published: 2012

Journal Articles

Analysis of Regulatory miRNAs of Histone Demethylase JMJD3 In MDS CD34+ Hematoprogenitor Cells

Yue Wei, PhD, George Calin, PhD, Yu Jia, Hong Zheng, Sara McCay, Hui Yang, MD, PhD, Zhihong Fang, Guillermo Garcia-Manero, MD

Blood (2010) 116 (21): 609.

https://doi.org/10.1182/blood.V116.21.609.609

Published: 2010

Journal Articles

Levels of Nrf2 and Keap1 Are Associated with Poor Prognostic Features In Myelodysplastic Syndromes (MDS)

Francesco Paolo Tambaro, MD, PhD, Carlos Vigil, MD, Yumin Hu, PhD, Hui Yang, MD, PhD, Zhihong Fang, Jack Yu Jia, Hong Zheng, Yue Wei, PhD, Hagop Kantarjian, MD, Lucia Altucci, MD, PhD, Felicetto Ferrara, MD, Guillermo Garcia-Manero, MD

Blood (2010) 116 (21): 1874.

https://doi.org/10.1182/blood.V116.21.1874.1874

Published: 2010

Journal Articles

Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate

Yumin Hu, Weiqin Lu, Gang Chen, Hui Zhang, Yu Jia, Yue Wei, Hui Yang, Wan Zhang, Warren Fiskus, Kapil Bhalla, Michael Keating, Peng Huang, Guillermo Garcia-Manero

Blood (2010) 116 (15): 2732–2741.

https://doi.org/10.1182/blood-2009-11-256354

Published: 2010

Includes: Supplemental data

Journal Articles

The Combination of PEITC (Phenehyl Isothiocyanate) with a Histone Deacetylase Inhibitor (HDACi) Has Synergistic Antileukemia Activity by Overcoming a Redox-Mediated Resistance Pathway.

Yumin Hu, MD, PhD, Gang Chen, Yu Jia, Hui Zhang, Peng Huang, PhD, Kapil N. Bhalla, MD, Michael Keating, MD, Guillermo Garcia-Manero, MD

Blood (2009) 114 (22): 1739.

https://doi.org/10.1182/blood.V114.22.1739.1739

Published: 2009

NARROW

Progression signature underlies clonal evolution and dissemination of multiple myeloma

Overexpression of Histone Demethylase KDM6B in the Hematopoietic Compartment Promotes the Effect of Innate Immune Activation and Results in Myelodysplastic Syndrome (MDS)-like Phenotype in Mice

Overexpression of KDM6B, an Epigenetic and Innate Immune Regulator, Results in Hematopoietic Alterations of Mice Including Changes in Hematopoietic Stem Cells

Pharmacological Inhibition of Histone Demethylase JMJD3 Reduces Leukemia Cell Survival and Represses Production of the Cytokine CCL2 in MDS/AML

Association Between Down-Regulation of EZH2 and Abnormal Karyotype, Response to Hypomethylation Treatment, and Patient Survival in Myelodysplastic Syndromes

Association Between Downregulation of POT1 Expression and Chromosome 7 Deletion, Response to Hypomethylation Agent Treatment, and Patient Survival in Myelodysplastic Syndromes

Down-Regulated Expression Of Protection Of Telomeres 1 (POT1) Gene In Bone Marrow Hematopoietic Progenitor Cell Compartment Has Prognostic Value In Myelodysplastic Syndromes (MDS)

Assessment Of EZH2 Expression In CD34+ Bone Marrow Progenitor Cells Of Patients Of Myelodysplastic Syndromes (MDS)

Low frequency of H3.3 mutations and upregulated DAXX expression in MDS

Deregulation of TLR2-JMJD3 Innate Immunity Signaling, Including a Rare TLR2 SNP As a Potential Somatic Mutation, in Myelodysplastic Syndromes (MDS)

Serum Amyloid Protein A 1 (hSAA1) Is Overexpressed in Myelodysplastic Syndromes and Potentially Mediates Toll-Like Receptor 2 Innate Immunity Signaling in CD34+ Hematopoietic Stem Cells

Low Frequency of Molecular Alterations of H3.3-Atrx-Daxx Chromatin Remodeling Component Genes in Myelodysplastic Syndromes (MDS)

Toll-Like Receptor (TLR) Signaling Adaptor Protein MYD88 in Myelodysplastic Syndromes (MDS)

Analysis of Regulatory miRNAs of Histone Demethylase JMJD3 In MDS CD34+ Hematoprogenitor Cells

Levels of Nrf2 and Keap1 Are Associated with Poor Prognostic Features In Myelodysplastic Syndromes (MDS)

Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate

The Combination of PEITC (Phenehyl Isothiocyanate) with a Histone Deacetylase Inhibitor (HDACi) Has Synergistic Antileukemia Activity by Overcoming a Redox-Mediated Resistance Pathway.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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