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Marie Sébert
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Journal Articles

Enasidenib (ENA) Monotherapy in Patients with IDH2 mutated Myelodysplastic Syndrome (MDS), the Ideal Phase 2 Study By the GFM and Emsco Groups

Marie Sebert, Sylvie Chevret, Sophie Dimicoli-Salazar, Thomas Cluzeau, Odile Rauzy, Aspasia Stamatoulas Bastard, Kamel Laribi, Gaelle Fossard, Sylvain Thépot, Silke Gloaguen, Kristell Desseaux, Norbert Vey, Pierre Peterlin, Anne-Laure Taksin, Caroline Lejeune, Sophie Park, Anne Banos, Aristoteles Giagounidis, Emmanuel Gyan, Mario Ojeda-Uribe, Stefanie Groepper, Fatiha Chermat, Emmanuelle Clappier, Uwe Platzbecker, Pierre Fenaux, Lionel Ades
Journal: Blood
Blood (2024) 144 (Supplement 1): 1839.
https://doi.org/10.1182/blood-2024-201317
Published: 2024
Journal Articles

Prognostic Significance of Monocytic-like Phenotype in AML Patients Treated with Venetoclax and Azacytidine

Lin Pierre Zhao, Typhaine Dumas-Rivero, Lauren Barette, Lorea Aguinaga, Arij Cheffai, Pierre Lemaire, Stéphanie Mathis, Clémentine Chauvel, Reinaldo Dal Bello, Emmanuelle Clappier, Matthieu Duchmann, Pierre Fenaux, Marie Sebert, Lionel Ades, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 4316.
https://doi.org/10.1182/blood-2024-203353
Published: 2024
Journal Articles

Combining ESA and Luspatercept in Non-RS MDS Patients Having Failed ESA - Results of the Phase 1-2 Part a of the GFM Combola Study

Lionel Ades, Thomas Cluzeau, Thibault Comont, Lorea Aguinaga, Aspasia Stamatoullas, Mathieu Meunier, Emmanuel Gyan, Alice Garnier, Maud D'Aveni, Sylvain Thépot, Marie Sebert, Marius Moldovan, Anouk Walter Petrich, Karine Lemarie, Fatiha Chermat, Michaela Fontenay, Sylvie Chevret, Pierre Fenaux
Journal: Blood
Blood (2024) 144 (Supplement 1): 351.
https://doi.org/10.1182/blood-2024-204791
Published: 2024
Journal Articles

Phase 3 Study of Either Ivosidenib (IVO) Monotherapy or Azacitidine (AZA) Monotherapy in Patients with IDH1 Mutant Myelodysplastic Syndromes (MDS) Who Are Hypomethylating Agent (HMA) Naive (PyramIDH)

Marie Sebert, Uwe Platzbecker, David Valcarcel Ferreiras, Valeria Santini, Uma Borate, Stephanie M. Kapsalis, Lorene Simonot, Weishi Yuan, Prapti A. Patel, Guillermo Garcia-Manero
Journal: Blood
Blood (2024) 144 (Supplement 1): 1845.1.
https://doi.org/10.1182/blood-2024-198172
Published: 2024
Journal Articles

Phase I/II Clinical Trial Evaluating Azacitidine + Venetoclax + Donor Lymphocyte Infusion in Post-Transplant Relapse Myelodysplastic Syndromes and Acute Myeloid Leukemia: Preliminary Results of Ventograft, a GFM Study

Thomas Cluzeau, Marie Sebert, Michael Loschi, Lionel Ades, Sylvain Thepot, Martin Carre, Nicolas Duployez, Rosa Sapena, Fatiha Chermat, Claude Preudhomme, Pierre Fenaux, Marie Robin
Journal: Blood
Blood (2023) 142 (Supplement 1): 3246.
https://doi.org/10.1182/blood-2023-178021
Published: 2023
Journal Articles

The Splicing-Associated Network PAK1-Clk-SRRM1 Is a Critical Vulnerability to Overcome Chemoresistance in Acute Myeloid Leukemia

Camille Vaganay, Frank Ling, Lois M. Kelly, Duong Ho Nhat, Antoine Forget, Paul-Arthur Meslin, Hélène Pasquer, Rathana Kim, Marie Passet, Sofiane Fodil, Tony Huynh, Angela H Su, Christopher F Bassil, Matthieu Duchmann, Gabriela Alexe, Gael Fortin, Carine Legrand, Khansa Saadallah, Christopher Delaney, Kim Pacchiardi, Anja Kocijancic, Lisa Aziez, Nina Fenouille, Marie Sebert, Lionel Ades, Emmanuel Raffoux, Emmanuelle Clappier, Lina Benajiba, Kimberly Stegmaier, Kris C. Wood, Raphael Itzykson, Camille Lobry, Alexandre Puissant
Journal: Blood
Blood (2023) 142 (Supplement 1): 409.
https://doi.org/10.1182/blood-2023-186264
Published: 2023
Journal Articles

Lymphopenia Confers Poorer Prognosis in Myelodysplastic Neoplasms (MDS) with Very Low and Low IPSS-M

David Fandrei, Tony Huynh, Marie Sebert, Lorea Aguinaga, Valeria Bisio, Marion Espéli, Karl Balabanian, Hélène Moins-Teisserenc, Antoine Toubert, Nicolas Dulphy, Pierre Fenaux, Lionel Ades, Lin-Pierre Zhao
Journal: Blood
Blood (2023) 142 (Supplement 1): 4597.
https://doi.org/10.1182/blood-2023-187707
Published: 2023
Journal Articles

Efficacy and Safety of Luspatercept +/- Erythropoiesis-Stimulating Agent (ESA) in Patients with Myelodysplastic Syndromes with Ring Sideroblasts (MDS-RS): A French Multicenter Prospective Real-Life Registry

Thibault Comont, Maud D'Aveni, Laurence Schenone, Jose Miguel Torregrosa-Díaz, Lorea Aguinaga, Juan Pardo, Marie Sebert, Sorin Visanica, Clemence Santana, Lenaig Le Clech, Aspasia Stamatoullas, Sylvain Thepot, Etienne Daguindau, Guillaume Beziat, Teresa Botin, Sophie Dimicoli, Sophie Park, Etienne Paubelle, Bohrane Slama, Lise Willems, Houria Debarri, Emmanuel Gyan, Claire Calmettes, Odile Rauzy, Fatiha Chermat, Michaela Fontenay, Lionel Ades, Pierre Fenaux
Journal: Blood
Blood (2023) 142 (Supplement 1): 6471.
https://doi.org/10.1182/blood-2023-177787
Published: 2023
Journal Articles

IPSS-M in myelodysplastic neoplasms arising from aplastic anemia and paroxysmal nocturnal hemoglobinuria

Carmelo Gurnari, Pedro Henrique Prata, Luiz Fernando B. Catto, Arda Durmaz, Lise Larcher, Marie Sebert, Vincent Allain, Tariq Kewan, Simona Pagliuca, Andre L. Pinto, Mariana C. B. Inacio, Lucie Hernandez, Nathalie Dhedin, Sophie Caillat-Zucman, Emmanuelle Clappier, Flore Sicre de Fontbrune, Maria Teresa Voso, Valeria Visconte, Régis Peffault de Latour, Jean Soulier, Gérard Socié, Rodrigo T. Calado, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 141 (25): 3122–3125.
https://doi.org/10.1182/blood.2023020108
Published: 2023
Includes: Supplemental data
Journal Articles

Molecular International Prognostic Scoring System (IPSS-M) in Myelodysplastic Syndromes Arising from Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Carmelo Gurnari, Pedro H. Prata, Luiz Fernando Bazzo Catto, Arda Durmaz, Lise Larcher, Marie Sebert, Vincent Allain, Tariq Kewan, Simona Pagliuca, Andre Luiz Pinto, Mariana C. B. Inacio, Lucie Hernandez, Nathalie Dhedin, Sophie Caillat-Zucman, Emmanuelle Clappier, Flore Sicre de Fontbrune, Maria Teresa Voso, Valeria Visconte, Régis Peffault de Latour, Jean Soulier, Gérard Socié, Rodrigo T. Calado, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2022) 140 (Supplement 1): 5788–5789.
https://doi.org/10.1182/blood-2022-160458
Published: 2022
Journal Articles

Prognostic impact of DDX41 germline mutations in intensively treated acute myeloid leukemia patients: an ALFA-FILO study

Clinical Trials & Observations
Nicolas Duployez, Laëtitia Largeaud, Matthieu Duchmann, Rathana Kim, Julie Rieunier, Juliette Lambert, Audrey Bidet, Lise Larcher, Jean Lemoine, François Delhommeau, Pierre Hirsch, Laurène Fenwarth, Olivier Kosmider, Justine Decroocq, Anne Bouvier, Yannick Le Bris, Marlène Ochmann, Alberto Santagostino, Lionel Adès, Pierre Fenaux, Xavier Thomas, Jean-Baptiste Micol, Claude Gardin, Raphael Itzykson, Jean Soulier, Emmanuelle Clappier, Christian Recher, Claude Preudhomme, Arnaud Pigneux, Hervé Dombret, Eric Delabesse, Marie Sébert
Journal: Blood
Blood (2022) 140 (7): 756–768.
https://doi.org/10.1182/blood.2021015328
Published: 2022
Includes: Supplemental data
Journal Articles

Clinical, pathological, and molecular features of myelodysplasia cutis

Clinical Trials & Observations
Jérémie Delaleu, Rathana Kim, Lin-Pierre Zhao, Adèle de Masson, Marie-Dominique Vignon-Pennamen, Charles Cassius, Caroline Ram-Wolff, Martine Bagot, Emmanuelle Clappier, Lionel Adès, Marie Sebert, Jean-David Bouaziz, Pierre Fenaux, Maxime Battistella
Journal: Blood
Blood (2022) 139 (8): 1251–1253.
https://doi.org/10.1182/blood.2021013967
Published: 2022
Includes: Supplemental data
Journal Articles

Ivosidenib Monotherapy Is Effective in Patients with IDH1 Mutated Myelodysplastic Syndrome (MDS): The Idiome Phase 2 Study By the GFM Group

Marie Sebert, Thomas Cluzeau, Odile Beyne Rauzy, Aspasia Stamatoulas Bastard, Sophie Dimicoli-Salazar, Sylvain Thepot, Pierre Peterlin, Sophie Park, Marie-Pierre Gourin, Oana Brehar, Cécile Bally, Sébastien Maury, Gaelle Fossard, Lamya Ait Si Selmi, Cendrine Chaffaut, Emmanuelle Clappier, Raphael Itzykson, Fatiha Chermat, Sylvie Chevret, Pierre Fenaux, Lionel Ades
Journal: Blood
Blood (2021) 138 (Supplement 1): 62.
https://doi.org/10.1182/blood-2021-146932
Published: 2021
Journal Articles

Enasidenib (ENA) Is Effective in Patients with IDH2 Mutated Myelodysplastic Syndrome (MDS) : The Ideal Phase 2 Study By the GFM Group

Lionel Ades, Sophie Dimicoli-Salazar, Marie Sebert, Thomas Cluzeau, Aspasia Stamatoulas Bastard, Kamel Laribi, Gaelle Fossard, Raphael Itzykson, Odile Beyne Rauzy, Alice Garnier, Silke Gloaguen, Norbert Vey, Caroline Le Jeune, Aristoteles Giagounidis, Emmanuel Gyan, Baptiste Perard, Sylvain Thepot, Mario Ojeda, Fatiha Chermat, Kristell Desseaux, Emmanuelle Clappier, Sylvie Chevret, Uwe Platzbecker, Pierre Fenaux
Journal: Blood
Blood (2021) 138 (Supplement 1): 63.
https://doi.org/10.1182/blood-2021-147898
Published: 2021
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation (allo HSCT) in Patients with IPSS Low or Intermediate-1 Myelodysplastic Syndrome (MDS): A Prospective Multicenter Phase II Study Based on Donor Availability By the GFM & SFGM-TC "MDS-ALLO-Risk"

Marie Sebert, Cendrine Chaffaut, Sylvain Thepot, Corentin Orvain, Thomas Cluzeau, Michael Loschi, Pierre Peterlin, Patrice Chevallier, Maud d'Aveni, Marie-Thérèse Rubio, Odile Beyne Rauzy, Anne Huynh, Amandine Charbonnier, Nathalie Fegueux, Gaelle Fossard, Stephanie N'guyen-Quoc, Sophie Park, Rosa Sapena, Fatiha Chermat, Lionel Ades, Sylvie Chevret, Pierre Fenaux, Marie Robin
Journal: Blood
Blood (2021) 138 (Supplement 1): 1842.
https://doi.org/10.1182/blood-2021-146846
Published: 2021
Journal Articles

Immunogenetic, Molecular and Clinical Determinants of Clonal Evolution in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Carmelo Gurnari, Simona Pagliuca, Pedro H. Prata, Luiz Fernando Bazzo Catto, Lise Larcher, Marie Sebert, Vincent Allain, Bhumika J. Patel, Laila Terkawi, Andre Luiz Pinto, Mariana Carolina Beraldo Ignacio, Lucie Hernandez, Nathalie Dhedin, Sophie Caillat-Zucman, Emmanuelle Clappier, Flore Sicre de Fontbrune, Maria Teresa Voso, Valeria Visconte, Gerard Socié, Rodrigo T. Calado, Regis Peffault De Latour, Jean Soulier, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2021) 138 (Supplement 1): 602.
https://doi.org/10.1182/blood-2021-147556
Published: 2021
Journal Articles

Prognostic Significance of DDX41 Germline Mutations in Intensively Treated AML Patients: An ALFA-Filo Study

Nicolas Duployez, Matthieu Duchmann, Laetitia Largeaud, Juliette Lambert, Audrey Bidet, Emmanuelle Clappier, Xavier Thomas, Stephane de Botton, Claude Gardin, Christian Recher, Arnaud Pigneux, Raphael Itzykson, Claude Preudhomme, Hervé Dombret, Eric Delabesse, Marie Sebert
Journal: Blood
Blood (2021) 138 (Supplement 1): 612.
https://doi.org/10.1182/blood-2021-148465
Published: 2021
Journal Articles

Clonal Hematopoiesis Driven By MDM4 Amplification Defines a Canonical Route Towards Secondary MDS/AML in Fanconi Anemia Patients

Marie Sebert, Stéphanie Gachet, Thierry Leblanc, Alix Rousseau, Olivier Bluteau, Rathana KIM, Raouf Benabelali, Flore Sicre de Fontbrune, Loïc Maillard, Carèle Fedronie, Nadia Vasquez, Yves Bertrand, Jean-Hugues Dalle, Francois Sigaux, Sylvie Chevret, Gerard Socie, Hugues de Thé, Christophe Antoniewski, Dominique Bluteau, Regis Peffault De Latour, Jean Soulier
Journal: Blood
Blood (2021) 138 (Supplement 1): 860.
https://doi.org/10.1182/blood-2021-147811
Published: 2021
Journal Articles

Long Term Follow-up and Combined Phase 2 Results of Eprenetapopt (APR-246) and Azacitidine (AZA) in Patients with TP53 mutant Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia (AML)

David A. Sallman, Rami S. Komrokji, Amy E. DeZern, Marie Sebert, Guillermo Garcia-Manero, Ramy Rahmé, David P. Steensma, Jacqueline Lehmann che, Gail J. Roboz, Isabelle Madelaine, Mikkael A. Sekeres, Pierre Peterlin, Kendra Sweet, Odile Beyne Rauzy, Andrew T. Kuykendall, Christian Recher, Amy F McLemore, Aspasia Stamatoullas, Ling Zhang, Lise Willems, Qianxing Mo, Emmanuel Raffoux, Lisa Nardelli, Celine Berthon, Najla Al Ali, Bruno Quesnel, Eric Padron, Greg Korbel, Eyal C. Attar, Hagop Kantarjian, Alan F. List, Lionel Ades, Jeffrey E. Lancet, Pierre Fenaux, Thomas Cluzeau
Journal: Blood
Blood (2021) 138 (Supplement 1): 246.
https://doi.org/10.1182/blood-2021-153286
Published: 2021
Journal Articles

MDS/CMML with TET2 or IDH mutation Are Associated with Systemic Inflammatory and Autoimmune Diseases (SIAD) and T Cell Dysregulation

Lin-Pierre Zhao, MD, Maxime Boy, Celia Azoulay, Emmanuelle Clappier, PhD PharmD, Marie Sébert, MD PhD, Ludivine Amable, Jihene Klibi, Kamel Benlagha, Marion Espeli, Karl Balabanian, Claude Preudhomme, MD PhD, Alice Marceau, Raphael Itzykson, MD PhD, Arsène Mékinian, Olivier Fain, MD, Antoine Toubert, Pierre Fenaux, MD PhD, Nicolas Dulphy, Lionel Ades, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-141228
Published: 2020