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Hélène Cavé
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Journal Articles

ERG Intragenic Deletion Characterizes a Distinct Oncogenic Subtype of B-Cell Precursor Acute Lymphoblastic Leukemia with a Favourable Outcome Despite Frequent IKZF1 Deletions

Emmanuelle Clappier, André Baruchel, Jérôme Rapion, Aurélie Caye, Ahlème Khemiri, Lucie Hernandez, Emmanuelle Kabongo, Thierry Leblanc, Karima Yakouben, Geneviève Plat, Vitor Costa, Alina Ferster, Séraphine Rossi, Sandrine Girard, Nicole Dastugue, Marleen Bakkus, Stefan Suciu, Yves Benoit, Yves Bertrand, Jean Soulier, Hélène Cavé
Journal: Blood
Blood (2012) 120 (21): 121.
https://doi.org/10.1182/blood.V120.21.121.121
Published: 2012
Journal Articles

Low CNS Relapse Incidence without Radiotherapy and Improvement of Outcome: Results of Subsequent EORTC-CLG 58881 and 58951 Trials in Pediatric T-Cell Acute Lymphoblastic Leukemia (ALL)

Barbara De Moerloose, Stefan Suciu, Alina Ferster, Françoise Mazingue, Nicolas Sirvent, Vitor Costa, Karima Yakouben, Patrick Lutz, Anne Uyttebroeck, Dominique Plantaz, Geneviève Plat, Frédéric Millot, Pierre Rohrlich, Maryline Poiree, Jutte Van der Werff Ten Bosch, Claire Hoyoux, Patrick Boutard, Hélène Cavé, PhD, Sandrine Girard, Francisco Bautista Sirvent, Yves Benoit, Yves Bertrand
Journal: Blood
Blood (2012) 120 (21): 133.
https://doi.org/10.1182/blood.V120.21.133.133
Published: 2012
Journal Articles

NRAS:BCL-2 Complex Localization Determines Anti-Apoptotic Features Associated with Progressive Disease in Myelodysplastic Syndromes (MDS)

Rose Ann Padua, PhD, Carole Le Pogam, MSc, Patricia Krief, PhD, Stephanie Beurlet, DMV, PhD, Bruno Cassinat, PharmD, PhD, Hélène Cavé, PhD, Olivier Kosmider, MD, PhD, Niclas Setterblad, PhD, Christophe Leboeuf, PhD, Laure Sarda-Mantel, MD, PhD, Florence Hervatin, PhD, Pascal Merlet, MD, Maria-Elena Noguera, MD, Anne Janin, MD, PhD, Marika Pla, PhD, Michaela Fontenay, MD, PhD, Lionel Ades, MD, PhD, Pierre Fenaux, MD, PhD, Christine Chomienne, MD, PhD, Nader Omidvar, PhD
Journal: Blood
Blood (2012) 120 (21): 3835.
https://doi.org/10.1182/blood.V120.21.3835.3835
Published: 2012
Journal Articles

Prolonged E. Coli Asparaginase Therapy Does Not Improve Significantly the Outcome for Children with Low and Average Risk Acute Lymphoblastic Leukemia (ALL) and Non Hodgkin Lymphoma (NHL): Final Report of the EORTC-CLG Randomized Phase III Trial 58951

Veerle Mondelaers, Stefan Suciu, Barbara De Moerloose, Alina Ferster, MD, Françoise Mazingue, Geneviève Plat, Karima Yakouben, Anne Uyttebroeck, Patrick Lutz, Vitor Costa, Nicolas Sirvent, Pierre Rohrlich, Martine Munzer, Maryline Poiree, Patrick Boutard, Frédéric Millot, Dominique Plantaz, Philip Maes, Claire Hoyoux, Hélène Cavé, PhD, Yves Bertrand, Yves Benoit
Journal: Blood
Blood (2012) 120 (21): 134.
https://doi.org/10.1182/blood.V120.21.134.134
Published: 2012
Journal Articles

The Prognosis of Children Acute Lymphoblastic Leukemia (ALL) with Minimal Residual Disease (MRD) ≥10-2 After Induction (TP1) Depends on the Prephase Response and on the Level of the MRD After Consolidation (TP2): Results of the 58951EORTC Trial

Yves Bertrand, Stefan Suciu, Nathalie Grardel, Marleen Bakkus, PhD, Francoise Mazingue, MD, Karima Yacouben, Anne Uyttebroeck, Patrick Lutz, Dominique Plantaz, Sandrine Girard, Nicole Dastugue, Yves Benoit, MD, Hélène Cavé
Journal: Blood
Blood (2011) 118 (21): 2571.
https://doi.org/10.1182/blood.V118.21.2571.2571
Published: 2011
Journal Articles

International Standardization of Minimal Residual Disease Assessment for in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL) Expressing m-BCR-ABL Transcripts: Updated Results of Quality Control Procedures by the EWALL and ESG-MRD-ALL Consortia

Heike Pfeifer, MD, Giovanni Cazzaniga, Orietta Spinelli, Jean-Michel Cayuela, Hélène Cavé, Peter Vandenberghe, MD, PhD, Carmen Chillon, Tomasz Sacha, MD, Sandrine Hayette, PhD, Silja Roettgers, PhD, Thomas Lion, MD, PhD, Professor, Letizia Foroni, MD PhD, Vincent H.J. van der Velden, PhD, Jan Zuna, Monica Hermanson, PhD, Martin Christian Mueller, MD, Thoralf Lange, Miroslaw Majewski, MD, Israel Bendit, MD, Fabrizio Pane, Ilaria Iacobucci, PhD, Veli Kairisto, MD, PhD, Christa Homburg, Smadar Avigad, Eng Juh Allen Yeoh, Beat Schäfer, Adele Fielding, Loredana Elia, Katarzyna Borg, Eric Delabesse, Susanne Schnittger, PhD, Sandra Markovic, Volker Werner, Nicola Goekbuget, MD, Dieter Hoelzer, MD, Jacques J.M. van Dongen, PhD, Oliver G. Ottmann, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2535.
https://doi.org/10.1182/blood.V118.21.2535.2535
Published: 2011
Journal Articles

Acute Lymphoblastic Leukemia in Children with Down Syndrome: A Report From the Ponte Di Legno Study Group,

Trudy Buitenkamp, MSc, #, Shai Izraeli, Martin Zimmermann, PhD, Erik Forestier, Nyla A. Heerema, PhD, Marry M. van den Heuvel, MD, PhD, Rob Pieters, MD, PhD, Válerie de Haas, MD, PhD, Lewis B. Silverman, MD, Kjeld Schmiegelow, MD, Der-Cherng Liang, Keizo Horibe, MD, PhD, Maurizio Arico, MD, Giovanni Cazzaniga, Giuseppe Basso, Karen R. Rabin, MD, Martin Schrappe, MD, Gunnar Cario, MD, Georg Mann, MD, Veerle Mondelaers, Tim Lammens, Hélène Cavé, Batia Stark, Anthony V. Moorman, Ajay J Vora, Stephen Hunger, MD, Ching-Hon Pui, MD, Charles G Mullighan, MBBS, MD, FRACP, FRCPA, MSc, Atsushi Manabe, Gabriele Escherich, MD, Jerzy Kowalczyk, MD, PhD, James A. Whitlock, MD, Christian M. Zwaan, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3579.
https://doi.org/10.1182/blood.V118.21.3579.3579
Published: 2011
Journal Articles

Minimal Residual Disease At 3 Months, Combined to the Presence of IKZF1 Deletion in B-Lineage or Absence of NOTCH1 pathway Mutation in T-Lineage, Recapitulates the Disease Risk Assessment in Adults with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia - A GRAALL Study

Kheira Beldjord, Elizabeth Macintyre, Véronique Lhéritier, Marie-Laure Boulland, MD, Thibaut Leguay, MD, Xavier Thomas, MD, PhD, Jean-Michel Cayuela, Nathalie Grardel, Yves Chalandon, MD, Nicolas Boissel, Beat Schäfer, Hélène Cavé, Patrice Chevallier, Agnès Buzyn, Thierry Fest, MD, PhD, Vahid Asnafi, Oumedaly Reman, MD, Marie-Christine Béné, Françoise Huguet, MD, Sylvie Chevret, Norbert Ifrah, Hervé Dombret
Journal: Blood
Blood (2011) 118 (21): 572.
https://doi.org/10.1182/blood.V118.21.572.572
Published: 2011
Journal Articles

In Childhood B-Lineage Acute Lymphoblastic Leukemia (B-ALL) with Hyperdiploidy >50 Chromosomes, Patients with 58 to 66 Chromosomes Have 99% EFS At 6-Year Follow-up: Results of the EORTC CLG 58951 Trial

Nicole Dastugue, Stefan Suciu, Geneviève Plat, Frank Speleman, PhD, Hélène Cavé, Sandrine Girard, Emmanuelle Delabesse, Marie Pierre Pagès, Karima Yakouben, Brigitte Nelken, Francoise Mazingue, MD, Anne Hagemeijer, Anne Uyttebroeck, Carine Gervais, MD, Patrick Lutz, Manuel Teixera, Lucilia Norton, Pierre Heimann, Alina Ferster, Ghislaine Plessis, Patrick Boutard, Marie Agnès Collonge, Pierre Rohrlich, MD, PhD, Isabelle Luquet, MD, PhD, Martine Munzer, Nicolas Sirvent, Dominique Plantaz, Christian Herens, Claire Hoyoux, Matthias Karrasch, Yves Bertrand, Yves Benoit, MD
Journal: Blood
Blood (2011) 118 (21): 565.
https://doi.org/10.1182/blood.V118.21.565.565
Published: 2011
Journal Articles

BCL11B Mutations In T-Cell Acute Lymphoblastic Leukemia

Kim De Keersmaecker, PhD, Pedro Jose Real, PhD, Giusy Della Gatta, PhD, Teresa Palomero, PhD, Maria Luisa Sulis, MD, Valeria Tosello, PhD, Pieter Van Vlierberghe, PhD, Kelly Barnes, Mireia Castillo, MD, Xavier Sole, PhD, Michael Hadler, Jack Lenz, PhD, Peter Aplan, MD, Michelle Kelliher, PhD, Barbara L. Kee, PhD, Pier Paolo Pandolfi, MD, PhD, Dietmar Kappes, PhD, Fotini Gounari, PhD, Howard Petrie, PhD, Joni Van der Meulen, Frank Speleman, PhD, Elisabeth Paietta, PhD, Janis Racevskis, Martin Tallman, MD, Jacob M. Rowe, MD, Jean Soulier, MD, PhD, David Avran, Hélène Cavé, MD, Nicole Dastugue, MD, Susana C. Raimondi, PhD, Jules Meijerink, PhD, Carlos Cordon-Cardo, MD, PhD, Andrea Califano, PhD, Adolfo Ferrando, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 471.
https://doi.org/10.1182/blood.V116.21.471.471
Published: 2010
Journal Articles

Post-Induction Minimal Residual Disease (MRD) Defines a Large Subset of Adults with Favorable Ph-Negative Acute Lymphoblastic Leukemia (ALL), Who Do Not Benefit From Allogeneic Stem Cell Transplantation (SCT) in First Complete Remission: A GRAALL Study.

Kheira Beldjord, Véronique Lhéritier, Marie-Laure Boulland, Nathalie Grardel, Jean-Michel Cayuela, Hélène Cavé, Beat Schäfer, Marleen Bakkus, Marlène Garrido, Nathalie Dhédin, Anne Huynh, Thibaut Leguay, Claude Gardin, Xavier Thomas, Yves Chalandon, Françoise Huguet, Jean-Paul Vernant, Thierry Fest, MD, PhD, Norbert Ifrah, Elizabeth Macintyre, Hervé Dombret
Journal: Blood
Blood (2009) 114 (22): 577.
https://doi.org/10.1182/blood.V114.22.577.577
Published: 2009
Journal Articles

Prognostic Significance of NOTCH1 and FBXW7 Mutations in Childhood T-Cell Acute Lymphoblastic Leukemia (T-ALL): Results From the EORTC Children Leukemia Group.

Emmanuelle Clappier, Sandra Collette, Nathalie Grardel, Sandrine Girard, Lydia Suarez, Ghislaine Brunie, Sophie Kaltenbach, Karima Yakouben, Françoise Mazingue, Alain Robert, Patrick Boutard, Dominique Plantaz, Pierre-Simon Rohrlich, Claude Preudhomme, Frank Speleman, Jacques Otten, Nicole Dastugue, Stefan Suciu, Yves Benoit, Yves Bertrand, Hélène Cavé
Journal: Blood
Blood (2009) 114 (22): 909.
https://doi.org/10.1182/blood.V114.22.909.909
Published: 2009
Journal Articles

Wilms' Tumor 1 (WT1) Gene Mutations in Pediatric T-Acute Lymphoblastic Leukemia.

Aline Renneville, Sophie Kaltenbach, Emmanuelle Clappier, Sandra Collette, Jean-Baptiste Micol, Brigitte Nelken, Pascale Lepelley, Nicole Dastugue, Yves Benoit, Yves Bertrand, MD, Claude Preudhomme, Hélène Cavé
Journal: Blood
Blood (2009) 114 (22): 3075.
https://doi.org/10.1182/blood.V114.22.3075.3075
Published: 2009
Journal Articles

Improved Prognosis of Children and Adolescents with Acute Lymphoblastic Leukemia (ALL) and Very-High Minimal Residual Disease (MRD) and the End of Induction therapy (EOI)? Preliminary Results of the FRALLE 2000 Protocol

Jean-Michel Cayuela, Kheira Beldjord, Sylvie Fasola, Marie-Françoise Auclerc, MD, Benoît Brethon, Anne Auvrignon, Francoise Mechinaud, Virginie Gandemer, MD, Geneviève Margueritte, Pascale Blouin, Nathalie Grardel, Hélène Cavé, Elizabeth Macintyre, Leverger Leverger, MD, PhD, Andre Baruchel, MD
Journal: Blood
Blood (2008) 112 (11): 2541.
https://doi.org/10.1182/blood.V112.11.2541.2541
Published: 2008
Journal Articles

Minimal Residual Disease in High and Very High Risk ALL (HR/VHR-ALL) at the End of Induction (EOI) in FRALLE 2000 B and T Protocols.

Jean-Michel Cayuela, PhD, Kheira Beldjord, PhD, Nathalie Grardel, PhD, Hélène Cavé, PhD, Marie-Françoise Auclerc, MD, Anne Auvrignon, MD, Thierry Leblanc, MD, Yves Perel, MD, Françoise Mechinaud, MD, Claudine Schmitt, MD, Virginie Gandemer, MD, Pascale Schneider, MD, Claire Berger, MD, Xavier Rialland, MD, Catherine Paillard, MD, Odile Lejars, MD, Gerard Michel, MD, Guy Leverger, MD, Elizabeth A. Macintyre, MD, PhD, Andre Baruchel, MD
Journal: Blood
Blood (2007) 110 (11): 1427.
https://doi.org/10.1182/blood.V110.11.1427.1427
Published: 2007
Journal Articles

PAX5 Mutations Occur Frequently in Adult B-Cell Acute Lymphoblastic Leukemia (B-ALL) and Is Significantly Associated with BCR-ABL1 Fusion Gene.

Julien Familiades, Marina Bousquet, Nicole Dastugue, Marina Lafage-Pochitaloff, Béné Marie-Christine, Kheira Beldjord, Jean-Michel Cayuela, Nathalie Grardel, Claude Preudhomme, Hélène Cavé, Véronique Lhéritier, André Delannoy, Yves Chalandon, Norbert Ifrah, Arnaud Pigneux, Hervé Dombret, Elizabeth A. Macintyre, Françoise Huguet, Pierre Brousset, Cyril Broccardo, Eric Delabesse
Journal: Blood
Blood (2007) 110 (11): 2806.
https://doi.org/10.1182/blood.V110.11.2806.2806
Published: 2007
Journal Articles

The EuroChimerism Concept for a Standardized Approach to Chimerism Analysis Following Allogeneic Stem Cell Transplantation.

Thomas Lion, Marcel Tilanus, Hélène Cavé, Mark Lawler, Anna Serra, Andrea Biondi, Jacques van Dongen, Marcos González, Gisela Barbany, Eddy Roosnek, Colin Steward, Peter Bader
Journal: Blood
Blood (2006) 108 (11): 621.
https://doi.org/10.1182/blood.V108.11.621.621
Published: 2006
Journal Articles

Childhood Secondary ALL after ALL Treatment.

Jan Zuna, Cornelia Eckert, Hélène Cavé, Claus Meyer, Björn Schneider, Eva Fronkova, Katerina Muzikova, Denisa Mendelova, Patrick Boutard, André Schrauder, Jaroslav Sterba, Rolf Marschalek, Jan Stary, Jan Trka
Journal: Blood
Blood (2005) 106 (11): 852.
https://doi.org/10.1182/blood.V106.11.852.852
Published: 2005
Journal Articles

Is CDKN2A +/− CDKN2B and MTAP Inactivation of Prognostic Significance in B-Precursor Childhood Acute Lymphoblastic Leukemia? Results of EORTC Studies 58881 and 58951.

Delphine Mirebeau, MD, Cécile Acquaviva, PharmD, Stefan Suciu, PHD, Raphaëlle Bertin, PharmD, Alain Robert, MD, Patrick Boutard, MD, Françoise Méchinaud, MD, Emmanuel Plouvier, MD, Jacques Otten, MD, Etienne Vilmer, MD, Hélène Cavé, PharmD, PHD
Journal: Blood
Blood (2004) 104 (11): 1076.
https://doi.org/10.1182/blood.V104.11.1076.1076
Published: 2004
Journal Articles

Ras Pathway Activation in Childhood B-Lineage Acute Lymphoblastic Leukemia: Ras , Ptpn11 , and Flt3 Mutations.

Hélène Cavé, Sami Saba, Nathalie Philippe, Nathalie Grardel, Brigitte Nelken, Lucilia Norton, Alain Robert, Karima Yacouben, Etienne Vilmer, Yves Bertrand, Claude Preudhomme
Journal: Blood
Blood (2004) 104 (11): 166.
https://doi.org/10.1182/blood.V104.11.166.166
Published: 2004