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Elżbieta Patkowska
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Journal Articles

A compelling case for central pathology review of multiparameter flow cytometry measurable residual disease results in Acute Myeloid Leukemia (AML) clinical trials: Data from the PALG-AML1/2016 multicenter randomized study

Free
Agnieszka Wierzbowska, Anna Czyz, Agnieszka Pluta, Marta Libura, Magdalena Czemerska, Zuzanna Nowicka, Agata Majchrzak, Michał Soin, Anna Kopinska, Krzysztof Wozniczka, Martyna Wlodarczyk, Joanna Dziaczkowska, Krystyna Jagoda, Grzegorz Helbig, Karol Wojcik, Małgorzata Razny, Marta Sobas, Donata Szymczak, Tomasz Wrobel, Andrzej Szczepaniak, Jolanta Parulska, Lidia Gil, Magdalena Dutka, Krzysztof Lewandowski, Maria Bieniaszewska, Tomasz Gromek, Marek Hus, Edyta Cichocka, Janusz Hałka, Elżbieta Patkowska, Jolanta Wozniak, Ewa Lech-Marańda, Agata Obara, Agnieszka Kopacz, Katarzyna Dulik, Sebastian Giebel, Jerzy Holowiecki, Krzysztof Gawronski, Grzegorz Charlinski, Nuria Mencia-Trinchant, Pinkal Desai, Michael Samuel, Justin Kaner, Michal Bar-Natan, Jonathan Canaani, Ellen Ritchie, Monica Guzman, Sylvie Freeman, Gail Roboz
Journal: Blood
Blood (2025) 146 (Supplement 1): 1737.
https://doi.org/10.1182/blood-2025-1737
Published: 2025
Journal Articles

Tyrosine kinase inhibitors, low intensity chemotherapy and allohct for adults with Philadelphia-positive acute lymphoblastic leukemia. Results of the polish adult leukemia group (PALG) ALL7 protocol

Free
Sebastian Giebel, Elżbieta Patkowska, Anna Kopinska, Anna Szmigielska-Kaplon, Marta Baranska, Jacek Kwiatkowski, Agnieszka Piekarska, Krzysztof Gawronski, Marzena Watek, Jaroslaw Piszcz, Katarzyna Brzezniakiewicz-Janus, Janusz Hałka, Tomasz Gromek, Edyta Cichocka, Agnieszka Kopacz, Monika Paluszewska, Elzbieta Wiater, Aleksandra Butrym, Grzegorz Helbig, Ewa Lech-Maranda, Anna Czyz
Journal: Blood
Blood (2025) 146 (Supplement 1): 5134.
https://doi.org/10.1182/blood-2025-5134
Published: 2025
Journal Articles

Prospective assessment of measurable residual disease kinetics in intensively treated patients with Acute Myeloid Leukemia (AML) - results of the PALG-AML1/2016 study

Free
Agnieszka Wierzbowska, Agnieszka Pluta, Anna Czyz, Marta Libura, Magdalena Czemerska, Zuzanna Nowicka, Agata Majchrzak, Michał Soin, Anna Kopinska, Krzysztof Wozniczka, Martyna Wlodarczyk, Grzegorz Helbig, Karol Wojcik, Małgorzata Razny, Marta Sobas, Donata Szymczak, Tomasz Wrobel, Andrzej Szczepaniak, Lidia Gil, Magdalena Dutka, Maria Bieniaszewska, Tomasz Gromek, Marek Hus, Edyta Cichocka, Janusz Hałka, Elzbieta Patkowska, Ewa Lech-Marańda, Agata Obara, Agnieszka Kopacz, Katarzyna Dulik, Sebastian Giebel, Jerzy Holowiecki, Krzysztof Gawronski, Grzegorz Charlinski, Nuria Mencia-Trinchant, Pinkal Desai, Michael Samuel, Justin Kaner, Michal Bar-Natan, Ellen Ritchie, Jonathan Canaani, Monica Guzman, Sylvie Freeman, Gail Roboz
Journal: Blood
Blood (2025) 146 (Supplement 1): 344.
https://doi.org/10.1182/blood-2025-344
Published: 2025
Journal Articles

Correlation of Baseline Gene Mutations With Quizartinib Efficacy in Patients With FLT3 -ITD-Positive Newly Diagnosed Acute Myeloid Leukemia in the Phase 3 QuANTUM-First Trial

Free
Mark J. Levis, Pau Montesinos, Hee-Je Kim, Radovan Vrhovac, Elzbieta Patkowska, Pavel Zak, Po-Nan Wang, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F. Schlenk, Alexander E. Perl, Mitsuhiro Yazawa, Jaime E. Connolly Rohrbach, Venkat Thodima, Ken C. N. Chang, Li Liu, Karima Imadalou, Akash Nahar, Kristy Burns, Harry P. Erba
Journal: Blood
Blood (2024) 144 (Supplement 1): 848.
https://doi.org/10.1182/blood-2024-203303
Published: 2024
Journal Articles

Quantum-First: Effects of Quizartinib (Q) on RFS, OS, CIR, and MRD in Newly Diagnosed (nd) Patients (pts) with FMS-like Tyrosine Kinase 3-Internal Tandem Duplication-Positive (FLT3 -ITD+) Acute Myeloid Leukemia (AML) Who Received Continuation (CONT) Therapy (tx)

Free
Mark J. Levis, Harry Erba, Pau Montesinos, Elzbieta Patkowska, Jorge E. Cortes, Herve Dombret, Alexander E. Perl, Sergio Amadori, Jianxiang Wang, Richard F. Schlenk, Li Liu, Yasser M. Mostafa Kamel, Karima Imadalou, Abderrahmane Laadem, Mikkael A. Sekeres, Kristy Burns
Journal: Blood
Blood (2024) 144 (Supplement 1): 2890.
https://doi.org/10.1182/blood-2024-207305
Published: 2024
Journal Articles

A Polish Adult Leukemia Group (PALG) Prospective International Randomized Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) in Acute Myeloid Leukemia (AML) Patients ≤ 60 Years Old (PALG-AML1/2016) - Topline Results

Free
Agnieszka Wierzbowska, Agnieszka Pluta, Anna Czyz, Marta Libura, Sebastian Giebel, Michał Soin, Damian Mikulski, Kacper Kościelny, Wojciech Fendler, Magdalena Czemerska, Agata Majchrzak, Anna Kopinska, Krzysztof Woźniczka, Martyna Włodarczyk, Karol Wójcik, Grzegorz Helbig, Małgorzata Raźny, Marta Sobas, Tomasz Wróbel, Donata Szymczak, Andrzej Szczepaniak, Lidia Gil, Magdalena Dutka, Maria Bieniaszewska, Tomasz Gromek, Marek Hus, Edyta Cichocka, Janusz Hałka, Elzbieta Patkowska, Marzena Wątek, Jolanta Wozniak, Ewa Lech-Maranda, Agata Obara, Agnieszka Kopacz, Katarzyna Dulik, Grzegorz Charlinski, Jerzy Holowiecki, Andi Rustani, Ameenah Sukkur, Nuria Mencia-Trinchant, Pinkal Desai, Michael Samuel, Justin D. Kaner, Michal Bar-Natan, Jonathan Canaani, Ellen K. Ritchie, Monica L Guzman, Sylvie D Freeman, Gail J. Roboz
Journal: Blood
Blood (2024) 144 (Supplement 1): 970.
https://doi.org/10.1182/blood-2024-202365
Published: 2024
Journal Articles

Safety and Efficacy Results from CLI120-001 a Phase 1 Study in RR-AML and HR-MDS: Update from Higher Dose Levels

Free
Ewa Lech Marańda, Elżbieta Patkowska, Natalia Jakacka, Camille N. Abboud, Howard A. Burris, Scott R. Solomon, Noemi Angelosanto, Tomasz Rzymski, Peter Littlewood, Kamil Kuś, Agnieszka Sroka-Porada, Renata Dudziak, Hendrik Nogai, Axel Glasmacher, Terrence Bradley, Gautam Borthakur, Elie Mouhayar, Paweł Steckiewicz, Sylwia Kościółek- Zgódka, Agata Szymańska, Jan Maciej Zaucha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2913.
https://doi.org/10.1182/blood-2023-186620
Published: 2023
Journal Articles

Quantum-First Trial: FMS-like Tyrosine Kinase 3-Internal Tandem Duplication ( FLT3 -ITD)-Specific Measurable Residual Disease (MRD) Clearance Assessed through Induction (IND) and Consolidation (CONS) Is Associated with Improved Overall Survival (OS) in Newly Diagnosed (nd) FLT3 -ITD+ AML Patients (pts)

Free
Alexander Perl, Harry P. Erba, Pau Montesinos, Radovan Vrhovac, Elzbieta Patkowska, Heeje Kim, Pavel Zak, Po-Nan Wang, Jaime E Rohrbach, Ken C N Chang, Li Liu, Yasser Mostafa Kamel, Karima Imadalou, Arnaud Lesegretain, Jorge Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F Schlenk, Mark J. Levis
Journal: Blood
Blood (2023) 142 (Supplement 1): 832.
https://doi.org/10.1182/blood-2023-186785
Published: 2023
Journal Articles

Stratification Using ECOG, ADL and HCT-CI Scales, but Not CGA Enables Identifying Elderly AML Patients Fit for Intensive Chemotherapy - a Multicenter Study from Polish Adult Leukemia Group

Free
Bozena Katarzyna Budziszewska, Michał Łomiak, Joanna Barankiewicz, Elzbieta Patkowska, Grzegorz Helbig, Lukasz Bolkun, Anna Irga-Staniukiewicz, Anna Kiżewska, Agnieszka Piekarska, Anna Koclęga, Agnieszka Pluta, Marta Kuydowicz, Sylwia Kościółek- Zgódka, Edyta Cichocka, Agata Malenda, Karol Wójcik, Tomasz Gromek, Piotr Małecki, Sebastian Grosicki, Agnieszka Wierzbowska, Ewa Lech-Maranda
Journal: Blood
Blood (2023) 142 (Supplement 1): 4218.
https://doi.org/10.1182/blood-2023-189713
Published: 2023
Journal Articles

Quantum-First Trial: FLT3 -ITD-Specific MRD Clearance Is Associated with Improved Overall Survival

Free
Mark J. Levis, Harry P. Erba, Pau Montesinos, Radovan Vrhovac, Elzbieta Patkowska, Heeje Kim, Pavel Zak, Po-Nan Wang, Jaime E. Connolly Rohrbach, Ken CN Chang, James Hanyok, Li Liu, Yasser Mostafa Kamel, Arnaud Lesegretain, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F. Schlenk, Alexander Perl
Journal: Blood
Blood (2022) 140 (Supplement 1): 546–548.
https://doi.org/10.1182/blood-2022-162739
Published: 2022
Journal Articles

Impact of Allogeneic Hematopoietic Cell Transplantation in First Complete Remission in Addition to FLT3 Inhibition with Quizartinib in Acute Myeloid Leukemia with FLT3 -Internal Tandem Duplication: Results from the Quantum-First Trial

Free
Richard F. Schlenk, Pau Montesinos, Antonio Romero-Aguilar, Radovan Vrhovac, Elżbieta Patkowska, Hee-Je Kim, Pavel Zak, Po-Nan Wang, James Hanyok, Li Liu, Yasser Mostafa Kamel, Aziz Benzohra, Arnaud Lesegretain, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Alexander E. Perl, Mark J. Levis, Harry P. Erba
Journal: Blood
Blood (2022) 140 (Supplement 1): 2130–2132.
https://doi.org/10.1182/blood-2022-169011
Published: 2022
Journal Articles

Prognostic Impact of Persistent Measurable Residual Disease in Patients with Acute Myeloid Leukemia FLT3+ Treated with Intensive Chemotherapy Plus Midostaurin - a Retrospective Study of the Polish Adult Leukemia Group (PALG)

Free
Elzbieta Patkowska, Alicja Sadowska-Klasa, Jan Zaucha, Andrzej Szczepaniak, Lidia Gil, Lukasz Bolkun, Michal Gorka, Marta Antonina Libura, Renata Guzicka-Kazimierczak, Marta Anna Sobas, Anna Koclega, Jolanta Wozniak, Krzysztof Lewandowski, Iwona Solarska, Magdalena Wojtas, Aleksandra Leszczynska, Zuzanna Kandula, Edyta Subocz, Edyta Cichocka, Katarzyna Krawczyk, Dorota Hawrylecka, Agnieszka Pluta, Agnieszka Wierzbowska, Sebastian Giebel, Ewa Lech-Marańda
Journal: Blood
Blood (2022) 140 (Supplement 1): 11836–11837.
https://doi.org/10.1182/blood-2022-170126
Published: 2022
Journal Articles

A Polish Acute Leukemia Group Prospective Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) and Two Standard Salvage Regimens (FLAG-IDA vs CLAG-M) in Acute Myeloid Leukemia (AML) Patients ≤ 60 Years Old (PALG-AML1/2016)

Free
Agnieszka Wierzbowska, Anna Czyz, Agnieszka Pluta, Marta Antonina Libura, Sebastian Giebel, Piotr Stelmach, Magdalena Czemerska, Kinga Krawiec, Anna Kopinska, Krzysztof Wozniczka, Grzegorz Helbig, Janusz Halka, Marta Anna Sobas, Tomasz Wróbel, Andrzej Szczepaniak, Lidia Gil, Magdalena Dutka, Maria Bieniaszewska, Tomasz Gromek, Marek Hus, Elzbieta Patkowska, Marzena Watek, Ewa Lech-Marańda, Agnieszka Kopacz, Katarzyna Dulik, Jerzy Holowiecki, Agata Obara, Edyta Cichocka, Krzysztof Gawronski, Monika Mordak-Domagala, Ameenah Sukkur, Andi Rustani, Pinkal Desai, Michael Samuel, Nuria Mencia Trinchant, Sangmin Lee, Justin D. Kaner, Ellen Ritchie, Monica L. Guzman, Gail J. Roboz
Journal: Blood
Blood (2022) 140 (Supplement 1): 9013–9015.
https://doi.org/10.1182/blood-2022-166184
Published: 2022
Journal Articles

Pre-Transplant Multiparameter Flow Cytometric Measurable Residual Disease in Acute Myeloid Leukemia As an Independent Prognostic Factor for Survival after Myeloablative Allogeneic Hematopoietic Cell Transplantation

Free
Anna Czyz, Malgorzata Maria Sobczyk Kruszelnicka, Tomasz Czerw, Sebastian Giebel, Magdalena Dutka, Agnieszka Piekarska, Maria Bieniaszewska, Jan Zaucha, Maciej Majcherek, Marta Anna Sobas, Tomasz Wróbel, Barbara Nasilowska-Adamska, Halaburda Kazimierz, Andrzej Szczepaniak, Lidia Gil, Anna Kopinska, Grzegorz Helbig, Sylwia Bartyzel-Palinska, Patrycja Mensah-Glanowska, Agnieszka Tomaszewska, Agnieszka Pluta, Elzbieta Patkowska, Jolanta Wozniak, Agnieszka Balana, Donata Szymczak, Jolanta Parulska, Ameenah Sukkur, Andi Rustani, Nuria Mencia Trinchant, Pinkal Desai, Michael Samuel, Justin D. Kaner, Ellen Ritchie, Monica L. Guzman, Gail J. Roboz, Agnieszka Wierzbowska
Journal: Blood
Blood (2022) 140 (Supplement 1): 7747–7749.
https://doi.org/10.1182/blood-2022-167407
Published: 2022
Journal Articles

Prospective Assessment of Measurable Residual Disease Kinetics in Intensively Treated Patients with Acute Myeloid Leukemia - Results of the Polish Adult Leukemia Group PALG-AML1/2016 Study

Free
Agnieszka Wierzbowska, Agnieszka Pluta, Anna Czyz, Marta Antonina Libura, Sebastian Giebel, Piotr Stelmach, Magdalena Czemerska, Piotr Strzałka, Anna Kopinska, Krzysztof Wozniczka, Grzegorz Helbig, Karol Wojcik, Malgorzata Razny, Marta Anna Sobas, Tomasz Wróbel, Andrzej Szczepaniak, Lidia Gil, Magdalena Dutka, Maria Bieniaszewska, Tomasz Gromek, Marek Hus, Edyta Cichocka, Janusz Halka, Elzbieta Patkowska, Marzena Watek, Jolanta Wozniak, Ewa Lech-Marańda, Agnieszka Kopacz, Katarzyna Dulik, Jerzy Holowiecki, Michal Soin, Damian Mikulski, Ewelina Perdas, Wojciech Fendler, Ameenah Sukkur, Andi Rustani, Nuria Mencia Trinchant, Pinkal Desai, Sangmin Lee, Michael Samuel, Justin D. Kaner, Ellen Ritchie, Monica L. Guzman, Gail J. Roboz
Journal: Blood
Blood (2022) 140 (Supplement 1): 6241–6243.
https://doi.org/10.1182/blood-2022-156950
Published: 2022
Journal Articles

Treatment and Disease Characteristics of Chronic Myeloid Leukemia in Blast Crisis: The European Leukemianet Blast Crisis Registry

Free
Annamaria Brioli, Elza Lomaia, Christian Fabisch, Tomasz Sacha, Hana Klamová, Elena Morozova, Aleksandra Golos, Philipp Ernst, Ulla Olsson-Strömberg, Jiri Mayer, Franck E. Nicolini, Han Bao, Fausto Castagnetti, Elzbieta Patkowska, Klaus Hirschbühl, Edyta Paczkowska, Anne Parry, Astghik Voskanyan, Susanne Saussele, Georg-Nikolaus Franke, Alexander Kiani, Edgar Faber, Krzysztof Lewandowski, Stefan W. Krause, Elke Dammann, Peter Anhut, Justyna Gil, Thomas Südhoff, Sonja Heibl, Markus Pfirrmann, Andreas Hochhaus, Michael Lauseker
Journal: Blood
Blood (2022) 140 (Supplement 1): 818–820.
https://doi.org/10.1182/blood-2022-162252
Published: 2022
Journal Articles

Phase 3 trial of gilteritinib plus azacitidine vs azacitidine for newly diagnosed FLT3 mut+ AML ineligible for intensive chemotherapy

Free
Clinical Trials & Observations
Eunice S. Wang, Pau Montesinos, Mark D. Minden, Je-Hwan Lee, Michael Heuser, Tomoki Naoe, Wen-Chien Chou, Kamel Laribi, Jordi Esteve, Jessica K. Altman, Violaine Havelange, Anne-Marie Watson, Carlo Gambacorti-Passerini, Elzbieta Patkowska, Shufang Liu, Ruishan Wu, Nisha Philipose, Jason E. Hill, Stanley C. Gill, Elizabeth Shima Rich, Ramon V. Tiu
Journal: Blood
Blood (2022) 140 (17): 1845–1857.
https://doi.org/10.1182/blood.2021014586
Published: 2022
Includes: Supplemental data
Journal Articles

Results from a Global Randomized Phase 3 Study of Guadecitabine (G) Vs Treatment Choice (TC) in 302 Patients with Relapsed or Refractory (r/r) Acute Myeloid Leukemia after Intensive Chemotherapy (ASTRAL-2 Study)

Free
Gail J. Roboz, Guillermo Sanz, Elizabeth A. Griffiths, Karen Yee, Hagop Kantarjian, Christian Recher, Michael T. Byrne, Elzbieta Patkowska, Hee-Je Kim, Xavier Thomas, Ine Moors, Wendy Stock, Arpad Illes, Pierre Fenaux, Yasushi Miyazaki, Takahiro Yamauchi, Casey L. O'Connell, Yong Hao, Harold N. Keer, Mohammad Azab, Hartmut Dohner
Journal: Blood
Blood (2021) 138 (Supplement 1): 2344.
https://doi.org/10.1182/blood-2021-147769
Published: 2021
Journal Articles

Phase 3, Open-Label, Randomized Study of Gilteritinib and Azacitidine Vs Azacitidine for Newly Diagnosed FLT3 -Mutated Acute Myeloid Leukemia in Patients Ineligible for Intensive Induction Chemotherapy

Free
Eunice S. Wang, Pau Montesinos, Mark D. Minden, Je-Hwan Lee, Michael Heuser, Tomoki Naoe, Wen-Chien Chou, Kamel Laribi, Jordi Esteve, Jessica K. Altman, Violaine Havelange, Anne-Marie Watson, Elzbieta Patkowska, Shufang Liu, Ruishan Wu, Nisha Philipose, Jason E. Hill, Stanley Gill, Elizabeth Shima Rich, Ramon V. Tiu
Journal: Blood
Blood (2021) 138 (Supplement 1): 700.
https://doi.org/10.1182/blood-2021-145379
Published: 2021
Journal Articles

The Prognostic Value of Early Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Treated with Intensive Chemotherapy - Preliminary Results of Polish Adult Leukemia Group PALG-AML1/2016 Study

Free
Agnieszka Wierzbowska, Agnieszka Pluta, Anna Czyz, Marta Antonina Libura, Sebastian Giebel, Magdalena Czemerska, Piotr Stelmach, Michal Soin, Anna Kopinska, Krzysztof Wozniczka, Grzegorz Helbig, Marta Sobas, Tomasz Wróbel, Andrzej Szczepaniak, Lidia Gil, Karol Wojcik, Malgorzata Razny, Magdalena Dutka, Maria Bieniaszewska, Janusz Halka, Tomasz Gromek, Marek Hus, Elzbieta Patkowska, Jolanta Wozniak, Edyta Cichocka, Agata Obara, Agnieszka Kopacz, Katarzyna Dulik, Jerzy Holowiecki, Damian Mikulski, Ewelina Perdas, Wojciech Fendler, Nicole M. Cruz, Nuria Mencia-Trinchant, Pinkal Desai, Sangmin Lee, Michael B. Samuel, Justin D. Kaner, Ellen Ritchie, Monica L. Guzman, Gail J. Roboz
Journal: Blood
Blood (2021) 138 (Supplement 1): 3453.
https://doi.org/10.1182/blood-2021-153520
Published: 2021