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Catherine R Marinac
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Journal Articles

Serum free light chains in a racially diverse population including African Americans and populations from South Africa

Luca Bertamini, Jean-Baptiste Alberge, David Jungpa Lee, Habib El-Khoury, Sungjae Kim, Grace Fleming, Ciara Suen Marie Murphy, Julia Colchie, Maya I Davis, Jacqueline Perry, Elizabeth D Lightbody, Sabine Allam, Lindokuhle N Goqwana, Vinitha Philip, Natalie Anne Smyth, NA, Dhananjay Sakrikar, Mark C Perkins, Stephen Harding, Derek Troske, Gad Getz, Elizabeth W Karlson, Nikhil C. Munshi, Kenneth C. Anderson, Lorenzo Trippa, Catherine R Marinac, Wenlong Carl Chen, Maureen Joffe, Irene M Ghobrial
Journal: Blood
Blood blood.2024026078.
https://doi.org/10.1182/blood.2024026078
Published: 2024
Includes: Supplemental data
Journal Articles

Landscape Assessment of the Perceptions of Distress and Symptom Burden in Patients with Monoclonal Gammopathy of Unknown Significance (MGUS) and Smoldering Multiple Myeloma (SMM)

Elizabeth K. O'Donnell, Jennifer Carroll, Jacqueline Perry, Katherine Padgett, Vidhi Patel, Omar Nadeem, Areej El-Jawahri, Irene Ghobrial, Catherine R. Marinac
Journal: Blood
Blood (2024) 144 (Supplement 1): 6872.
https://doi.org/10.1182/blood-2024-201747
Published: 2024
Journal Articles

Deep Learning Unveils Characteristics of Immune B Cell Aging in >17,000 Samples and Identifies Changes in the Immunoglobulin Repertoire Distribution and the Development of Monoclonal Gammopathy

Floris Chabrun, Jean-Baptiste Alberge, Sabine Allam, Jacqueline F Perry, Habib El-Khoury, David J Lee, Michael Timonian, Luca Bertamini, Hadley Barr, Grace Fleming, Joseph Casey Flinn, Ciara Murphy, Sofia Wallin, Hiba Hussain, Elizabeth D. Lightbody, Sungjae Kim, Mark C Perkins, Stephen J. Harding, Dhananjay Sakrikar, Romanos Sklavenitis Pistofidis, Kenneth C. Anderson, Omar Nadeem, Elizabeth K. O'Donnell, Yuxin Liu, Wenlong Chen, Maureen Joffe, Benjamin Levine Ebert, Catherine R. Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 4984.
https://doi.org/10.1182/blood-2024-194368
Published: 2024
Journal Articles

Association between Sleep Traits and Risk of Non-Hodgkin's Lymphoma Subtypes: A Mendelian Randomization Study in the International Lymphoma (InterLymph) Epidemiology Consortium

Pankhil Shah, Brittany Crawford, Anwar Merchant, Brenda M. Birmann, Angelica Macauda, Michelle A.T. Hildebrandt, Aaron D. Norman, Neil Caporaso, Meredith Yeager, Michael Dean, Immaculata De Vivo, Lynn Goldin, Nicola J Camp, Rosalie Griffin Waller, Delphine Casabonne, Federico Canzian, Pelin Unal, Elad Ziv, Catherine R. Marinac, Alexandra Nieters, Stephen J Chanock, Mitchell Machiela, Michael Conry, Han La Park, Simon Cheah, Jonathan Hofmann, Elizabeth E. Brown, Celine M. Vachon, Susan L. Slager, Sonja I. Berndt, Sophia S. Wang, Vijai Joseph, James McKay, Henrik Hjalgrim, Lara E. Sucheston-Campbell, Karl Smith-Byrne, Alyssa I Clay-Gilmour
Journal: Blood
Blood (2024) 144 (Supplement 1): 6182.
https://doi.org/10.1182/blood-2024-199373
Published: 2024
Journal Articles

Early Serum Protein Clonal Dynamics Preceding Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma Years before Diagnosis

Sabine Allam, Floris Chabrun, Jean-Baptiste Alberge, Grace Fleming, Sungjae Kim, Yoshinobu Konishi, Habib El-Khoury, Luca Bertamini, Sofia Wallin, Joseph Casey Flinn, Dhananjay Sakrikar, Derek Troske, David Barnidge, Mark C Perkins, Stephen J. Harding, Romanos Sklavenitis-Pistofidis, Paolo Ghia, Catherine R. Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 3279.
https://doi.org/10.1182/blood-2024-203937
Published: 2024
Journal Articles

Comprehensive Characterization of the Plasma Proteome of Multiple Myeloma and Its Precursor Conditions and Identification of a Proteomic Signature to Improve Risk Prediction of Disease Progression

Elizabeth D. Lightbody, D. R. Mani, Hasmik Keshishian, Namrata Udeshi, Romanos Sklavenitis-Pistofidis, Ankit K. Dutta, Ting Wu, Junko Tsuji, Habib El-Khoury, Hadley Barr, Sarah Nersesian, Nang Kham Su, Cody J. Boehner, Michael P. Agius, Michelle P. Aranha, Laura Hevenor, Katherine Towle, Grace Fleming, Christian Cea-Curry, Daniel Heilpern-Mallory, Erica M. Horowitz, Jacqueline F Perry, Maya Davis, Kelly Walsh, Annie Cowan, John E. Ready, Catherine R. Marinac, Gad Getz, Michael Gillette, Steven A. Carr, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1903.
https://doi.org/10.1182/blood-2024-209286
Published: 2024
Journal Articles

Improved Risk Stratification of Smoldering Multiple Myeloma (SMM) Using Trajectory Data in the Pangea 2.0 Model: A Multicenter Study in 1,431 Participants

Floris Chabrun, Daniel Schwartz, Susanna Gentile, Tulika R Gupta, Noelia Collado Gisbert, Esperanza Martín-Sánchez, Rosalinda Termini, Jacqueline F Perry, Annie Cowan, Federico Ferrari, Samuel Freeman, Robert A. Redd, Vidhi Patel, Patrick Costello, Catherine Tobia, Romanos Sklavenitis-Pistofidis, Habib El-Khoury, Michael Timonian, David J Lee, Elizabeth D. Lightbody, Hadley Barr, Priya Kaur, Katelyn Downey, Sally Phan, Maya Patel, Jennifer Lamb, Nana Ama Boadi-Acheampong, Foteini Theodorakakou, Despina Fotiou, Christine-Ivy Liacos, Selina J Chavda, Louise Ainley, Elizabeth K. O'Donnell, Catherine R. Marinac, Gad Getz, Omar Nadeem, Kwee Yong, Efstathios Kastritis, Meletios Dimopoulos, Jesús F. San-Miguel, Bruno Paiva, Lorenzo Trippa, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1017.
https://doi.org/10.1182/blood-2024-205705
Published: 2024
Journal Articles

High-Throughput Plasma Proteomics to Define the Precursor Multiple Myeloma Proteome and Identify Candidate High-Risk Disease Biomarkers of Progression

Elizabeth D. Lightbody, D. R. Mani, Hasmik Keshishian, Habib El-Khoury, Ankit K. Dutta, Hadley Barr, Namrata Udeshi, Luca Bertamini, Nang Kham Su, Cody J. Boehner, Laura Hevenor, Katherine Towle, Grace Fleming, Christian Cea-Curry, Jacqueline Perry, Erica M. Horowitz, Maya Davis, Annie Cowan, Catherine R. Marinac, Michael Gillette, Steven A. Carr, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 334.
https://doi.org/10.1182/blood-2023-189091
Published: 2023
Journal Articles

Understanding Patient Preferences for Intervention in Individuals with Precursor Multiple Myeloma: The Preference Study

Catherine R. Marinac, Katelyn Downy, Irene M. Ghobrial, Jacqueline Perry, Brittany Fischer-Longden, Timothy R Rebbeck, Elizabeth K. O'Donnell, Omar Nadeem, Brian Egleston
Journal: Blood
Blood (2023) 142 (Supplement 1): 4775.
https://doi.org/10.1182/blood-2023-190035
Published: 2023
Journal Articles

Large-Scale Characterization and Functional Assessment of Adaptive Immunity in Patients with MGUS and SMM Reveals Significant Defects

Michelle P. Aranha, Romanos Sklavenitis-Pistofidis, Yoshinobu Konishi, Ting Wu, Hong Yue, Elizabeth D. Lightbody, Mahshid Rahmat, Michael Timonian, Daniel L. Mallory, Michael P. Agius, Shohreh Varmeh, Nang Kham Su, Jacqueline Perry, Erica M. Horowitz, Maya Davis, Anna Justis, Radosław P. Nowak, Mark Hamilton, Daniel Auclair, Catherine R. Marinac, Eric Fischer, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 2548.
https://doi.org/10.1182/blood-2023-178062
Published: 2023
Journal Articles

Single-Cell RNA Sequencing of Circulating Tumor Cells in Precursor Myeloma Patients Reveals Mechanisms of Disease Dissemination

Elizabeth D. Lightbody, Romanos Sklavenitis-Pistofidis, Danielle T. Firer, Junko Tsuji, Mike P. Agius, Ankit K. Dutta, Ting Wu, Hadley Barr, Sungjae Kim, Tim Coorens, Jean-Baptiste Alberge, Michelle P. Aranha, Nicholas J Haradhvala, Nang Kham Su, Cody J. Boehner, Kelly Walsh, Mahshid Rahmat, Yoshinobu Konishi, Laura Hevenor, Katherine Towle, Erica M. Horowitz, Jacqueline Perry, Grace Fleming, Habib El-Khoury, Michael Vinyard, Annie Cowan, Daniel Auclair, John E. Ready, Catherine R. Marinac, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 872.
https://doi.org/10.1182/blood-2023-189760
Published: 2023
Journal Articles

Persistence of Monoclonal Gammopathies in Serial Samples from a US Population-Based Screening Study

Habib El-Khoury, Luca Bertamini, Jean-Baptiste Alberge, David J. Lee, Ciara Murphy, Grace Fleming, Christian J. Cea-Curry, Maya I. Davis, Jacqueline Perry, Elizabeth D. Lightbody, Dhananjay Sakrikar, Derek Troske, David Barnidge, Mark C. Perkins, Stephen Harding, Gad Getz, Catherine R. Marinac, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 10101–10103.
https://doi.org/10.1182/blood-2022-169380
Published: 2022
Journal Articles

Abnormal Free Light Chains in Individuals with African Ancestry Screened for Monoclonal Gammopathy: Definition of New Reference Range Accounting for Renal Function and Race

Luca Bertamini, Jean-Baptiste Alberge, Habib El-Khoury, David J. Lee, Ciara Murphy, Grace Fleming, Maya I. Davis, Jacqueline Perry, Christian J. Cea-Curry, Audrey Pentz, Thulisile Hlubi, Natalie Smyth, D.J. Sakrikar, Mark C. Perkins, Stephen Harding, Derek Troske, Gad Getz, Timothy R. Rebbeck, Maureen Joffe, Catherine R. Marinac, Nelson Leung, Carl Wenlong Chen, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 10005–10006.
https://doi.org/10.1182/blood-2022-164436
Published: 2022
Journal Articles

Dysregulated Humoral and Cellular Response to Sars-Cov-2 Vaccination in Patients with MGUS and SMM

Yoshinobu Konishi, Romanos Sklavenitis-Pistofidis, Michelle P. Aranha, Ting Wu, Hong Yue, Elizabeth D. Lightbody, Mahshid Rahmat, Michael Timonian, Shohreh Varmeh, Daniel Heilpern-Mallory, Michael P. Agius, Nang Kham Su, Jacqueline Perry, Erica Horowitz, Maya I. Davis, Anna V. Justis, Radoslaw P. Nowak, Mark Hamilton, Daniel Auclair, Catherine R. Marinac, Eric S. Fischer, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 7158–7159.
https://doi.org/10.1182/blood-2022-167212
Published: 2022
Journal Articles

High-Throughput Plasma Proteomic Profiling to Identify Candidate High-Risk Disease Biomarkers in Precursor Multiple Myeloma Patients

Elizabeth D. Lightbody, Hasmik Keshishian, Habib El-Khoury, Ankit K. Dutta, Hadley Barr, Jes Barbagallo, Namrata Udeshi, Michael P. Agius, Nang Kham Su, Cody J. Boehner, Laura Hevenor, Katherine Towle, Christian J. Cea-Curry, Jacqueline Perry, Erica Horowitz, Maya I. Davis, Anna Cowan, Evan Mills, Marijana Rucevic, DR Mani, Daniel Auclair, Catherine R. Marinac, Michael A Gillette, Steven A Carr, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 4303–4304.
https://doi.org/10.1182/blood-2022-170346
Published: 2022
Journal Articles

Single-Cell RNA Sequencing of Rare Circulating Tumor Cells in Precursor Myeloma Patients Reveals Molecular Underpinnings of Tumor Cell Circulation

Elizabeth D. Lightbody, Danielle T. Firer, Romanos Sklavenitis-Pistofidis, Junko Tsuji, Michael P. Agius, Ankit K. Dutta, Ting Wu, Hadley Barr, Mahshid Rahmat, Yoshinobu Konishi, Michelle P. Aranha, Michael Vinyard, Jean-Baptiste Alberge, Nang Kham Su, Cody J. Boehner, Laura Hevenor, Habib El-Khoury, Katherine Towle, Christian J. Cea-Curry, Erica Horowitz, Jacqueline Perry, Anna Cowan, Anna V. Justis, Daniel Auclair, Catherine R. Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 602–603.
https://doi.org/10.1182/blood-2022-162851
Published: 2022
Journal Articles

Prevalence of Monoclonal Gammopathies Detected By Mass Spectrometry and Their Risk Factors Among Black Africans in South Africa

David J. Lee, Habib El-Khoury, Luca Bertamini, Jean-Baptiste Alberge, Maya I. Davis, Jacqueline Perry, Dhananjay Sakrikar, David Barnidge, Mark C. Perkins, Stephen Harding, Derek Troske, Audrey Pentz, Thulisile Hlubi, Natalie Smyth, Anna Cowan, Angela C. Tramontano, Gad Getz, Timothy R. Rebbeck, Maureen Joffe, Wenlong Carl Chen, Catherine R. Marinac, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 7228–7229.
https://doi.org/10.1182/blood-2022-167268
Published: 2022
Journal Articles

Age-related diseases of inflammation in myelodysplastic syndrome and chronic myelomonocytic leukemia

Clinical Trials & Observations
Lachelle D. Weeks, Catherine R. Marinac, Robert Redd, Gregory Abel, Amy Lin, Mridul Agrawal, Richard M. Stone, Deborah Schrag, Benjamin L. Ebert
Journal: Blood
Blood (2022) 139 (8): 1246–1250.
https://doi.org/10.1182/blood.2021014418
Published: 2022
Includes: Supplemental data
Journal Articles

High Prevalence of Monoclonal Gammopathy in a Population at Risk: The First Results of the Promise Study

Habib El-Khoury, Jean-Baptiste Alberge, Hadley Barr, Ciara Murphy, D.J. Sakrikar, Tara Krause, David Barnidge, Mark Bustoros, Houry Leblebjian, Annie Cowan, Maya Davis, Julia Amstutz, Jacqueline Perry, Cody J. Boehner, Elizabeth D. Lightbody, Tarek H Mouhieddine, Romanos Sklavenitis-Pistofidis, Mark C Perkins, Stephen Harding, Prashant Kapoor, Clifton C. Mo, David L. Murray, Ivan M. Borrello, Gad Getz, Timothy R Rebbeck, Catherine R. Marinac, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 152.
https://doi.org/10.1182/blood-2021-149868
Published: 2021
Journal Articles

A Randomized Placebo-Controlled Phase 2 Study of Metformin for the Prevention of Progression of Monoclonal Gammopathy of Undetermined Significance and Low Risk Smoldering Multiple Myeloma

Catherine R. Marinac, Robert A. Redd, Julia Prescott, Alexandra Savell, Courtney Igne, Jacob P. Laubach, Adam S. Sperling, Aric D. Parnes, Houry Leblebjian, Paul G. Richardson, Irene M. Ghobrial, Omar Nadeem
Journal: Blood
Blood (2021) 138 (Supplement 1): 1659.
https://doi.org/10.1182/blood-2021-151878
Published: 2021