Skip Nav Destination
            
    
            
 
    
    
        
            
                
                    
                        
                        
                            
                        
                    
                
                    
                    
                        
                    
                
                
                    
                        
                        
                            
                        
                    
            
        
    
    
    
        
        
        
    
        
 
    
        
    
    
        
            
        
        
    
        
    
    
    
 
    
                
                    
            
    
        
    
    
                     
    
                     
    
                    
        
        
     
    
                    
        
        
     
    
                    
                    
        
        CHAMPION-1: a phase 1/2 study of once-weekly carfilzomib and dexamethasone for relapsed or refractory multiple myeloma
        
        
            
        
    
        
                
            
    
    
    
        
        
     
    
                     
    
                    
                    
        
        Impairment of dendritic cell functions in patients with adaptor protein-3 complex deficiency
        
        
            
        
    
        
                
            
    
    
    
        
        
     
    
                    
                    
                
            
    
    
    
        
        
     
    
                    
                    
                
            
    
    
    
                    
        
        Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study
        
        
            
        
    
        
                
            
    
    
    
        
        
     
    
                     
    
                     
    
                    
                    
        
        Single- vs double-unit cord blood transplantation for children and young adults with acute leukemia or myelodysplastic syndrome
        
        
            
        
    
        
                
            
    
    
    
        
        
     
    
                    
        
        
     
    
                     
    
 
    
            
    
        
    
         
 
    
    
        
    
            
    
        
    
    
    
        
    
    
    
            
    
                    
 
    
    
 
    
    
        
    
    
    
            
        
 
    
    
 
    
    
         
    
    
        
    
    
    
            
    
                    
 
    
    
 
    
    
 
    
    
    
    
        
    Issue Archive
June 30 2016
    
    
Table of Contents
EDITORIAL
BLOOD FLASHBACK
INSIDE BLOOD COMMENTARIES
REVIEW SERIES
CLINICAL TRIALS AND OBSERVATIONS
        
        CHAMPION-1: a phase 1/2 study of once-weekly carfilzomib and dexamethasone for relapsed or refractory multiple myeloma
        
        
            
        
                    
                        Clinical Trials & Observations
                    
        
            
    
        
            James R. Berenson,Alan Cartmell,Alberto Bessudo,Roger M. Lyons,Wael Harb,Dimitrios Tzachanis,Richy Agajanian,Ralph Boccia,Morton Coleman,Robert A. Moss,Robert M. Rifkin,Priti Patel,Sandra Dixon,Ying Ou,Janet Anderl,Sanjay Aggarwal,Jesus G. Berdeja
            
        
    
            HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY
        
        Impairment of dendritic cell functions in patients with adaptor protein-3 complex deficiency
        
        
            
        
                    
                        Brief Report
                    
        
            
    
        
            Alberto Prandini,Valentina Salvi,Francesca Colombo,Daniele Moratto,Luisa Lorenzi,William Vermi,Maria Antonia De Francesco,Lucia Dora Notarangelo,Fulvio Porta,Alessandro Plebani,Fabio Facchetti,Silvano Sozzani,Raffaele Badolato
            
        
    
            LYMPHOID NEOPLASIA
Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome
            Wesley J. Woollard,Venu Pullabhatla,Anna Lorenc,Varsha M. Patel,Rosie M. Butler,Anthony Bayega,Nelema Begum,Farrah Bakr,Kiran Dedhia,Joshua Fisher,Silvia Aguilar-Duran,Charlotte Flanagan,Aria A. Ghasemi,Ricarda M. Hoffmann,Nubia Castillo-Mosquera,Elisabeth A. Nuttall,Arisa Paul,Ceri A. Roberts,Emmanouil G. Solomonidis,Rebecca Tarrant,Antoinette Yoxall,Carl Z. Beyers,Silvia Ferreira,Isabella Tosi,Michael A. Simpson,Emanuele de Rinaldis,Tracey J. Mitchell,Sean J. Whittaker
            
        
    
            MYELOID NEOPLASIA
A thrombopoietin receptor antagonist is capable of depleting myelofibrosis hematopoietic stem and progenitor cells
            Xiaoli Wang,David Haylock,Cing Siang Hu,Wioleta Kowalczyk,Tianbo Jiang,Jiajing Qiu,Goar Mosoyan,Wu He,Netonia Marshall,John Mascarenhas,Anna Tarasova,Joshua Brody,David Winkler,Ronald Hoffman
            
        
    
            
        
        Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study
        
        
            
        
                    
                        Clinical Trials & Observations
                    
        
            
    
        
            Jasmijn D. E. de Rooij,Riccardo Masetti,Marry M. van den Heuvel-Eibrink,Jean-Michel Cayuela,Jan Trka,Dirk Reinhardt,Mareike Rasche,Edwin Sonneveld,Todd A. Alonzo,Maarten Fornerod,Martin Zimmermann,Martina Pigazzi,Rob Pieters,Soheil Meshinchi,C. Michel Zwaan,Franco Locatelli
            
        
    
            PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
THROMBOSIS AND HEMOSTASIS
TRANSPLANTATION
        
        Single- vs double-unit cord blood transplantation for children and young adults with acute leukemia or myelodysplastic syndrome
        
        
            
        
                    
                        Clinical Trials & Observations
                    
        
            
    
        
            Gérard Michel,Claire Galambrun,Anne Sirvent,Cecile Pochon,Benedicte Bruno,Charlotte Jubert,Anderson Loundou,Ibrahim Yakoub-Agha,Noel Milpied,Patrick Lutz,Aude Marie-Cardine,Virginie Gandemer,Didier Blaise,Mauricette Michallet,Fanny Rialland,Cecile Renard,Claire Oudin,Sophie Esmiol,Mylene Seux,Karine Baumstarck,Mohamad Mohty,Vanderson Rocha,Jean-Hugues Dalle
            
        
    
            BLOOD WORK
ERRATA
- 
        
            Cover Image
        
        Cover Image![issue cover]()  Dispersed cells showing abnormal megakaryocyte maturation and a block to erythroid differentiation from colonies obtained from the expanded pool of megakaryocyte/erythroid progenitors isolated from Runx1-deficient mice. The authors demonstrate that in addition to the important role of Runx1 in supporting megakaryocyte maturation, it is also an essential suppressor of lineage commitment toward megakaryopoiesis. See the article by Behrens et al on page 3369. 
- PDF Icon Front MatterFront Matter
- PDF Icon Table of ContentsTable of Contents
- PDF Icon Back MatterBack Matter
- PDF Icon Editorial BoardEditorial Board
Advertisement intended for health care professionals
Email alerts
Advertisement intended for health care professionals
 
                    