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Journal Articles

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Kamaleldin E Elagib, PhDMBBS, Ashton Brock, PhD, Goar Mosoyan, Cara Clementelli, Lorrie L Delehanty, BS, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, PhD, Stephen Morris, MD, Koji Eto, MD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD

Blood (2019) 134 (Supplement_1): 3250.

https://doi.org/10.1182/blood-2019-129049

Published: 2019

Journal Articles

Preclinical Development of a Cryopreservable Megakaryocyte Cell Product from Cord Blood Derived Hematopoietic Stem Cells

Helen Fong, PhD, Goar Mosoyan, Ami Patel, MS, Ronald Hoffman, MD, Jay Tong, MD, Camelia Iancu-Rubin, PhD

Blood (2016) 128 (22): 3859.

https://doi.org/10.1182/blood.V128.22.3859.3859

Published: 2016

Journal Articles

An IGF2BP3-Cdk9 Pathway Governs the Human Fetal-Adult Megakaryocyte Transition

Kamaleldin E Elagib, MBBS, PhD, Chih-Huan Lu, BS, Goar Mosoyan, Ewelina Zasadzińska, MS, Daniel R Foltz, PhD, Peter Balogh, Els Verhoeyen, Miriam Sansó, PhD, Robert P Fisher, MD PhD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD

Blood (2016) 128 (22): 886.

https://doi.org/10.1182/blood.V128.22.886.886

Published: 2016

Journal Articles

Preclinical Development of a Cord Blood (CB)-Derived Hematopoietic Stem Cell (HSC) Product for Allogeneic Transplantation in Patients with Hematological Malignancies

Camelia Iancu-Rubin, PhD, Helen Fong, PhD, Goar Mosoyan, Ami Patel, MS, Rachel Sabado, PhD, Meseck Marcia, MS, Erin Moshier, MS, Umut Ozbek, PhD, Alla Keyzner, MD, Nina Bhardwaj, MD PhD, Ian K. McNiece, PhD, Jay Tong, MD, Ronald Hoffman, MD

Blood (2016) 128 (22): 818.

https://doi.org/10.1182/blood.V128.22.818.818

Published: 2016

Journal Articles

A thrombopoietin receptor antagonist is capable of depleting myelofibrosis hematopoietic stem and progenitor cells

Xiaoli Wang, David Haylock, Cing Siang Hu, Wioleta Kowalczyk, Tianbo Jiang, Jiajing Qiu, Goar Mosoyan, Wu He, Netonia Marshall, John Mascarenhas, Anna Tarasova, Joshua Brody, David Winkler, Ronald Hoffman

Blood (2016) 127 (26): 3398–3409.

https://doi.org/10.1182/blood-2015-10-674465

Published: 2016

Includes: Supplemental data

Journal Articles

A Thrombopoietin Antagonist Is Capable of Affecting Stem and Progenitor Cells of Patients with Myelofibrosis

Xiaoli Wang, David Haylock, Cing Siang Hu, Goar Mosoyan, Dave Winkler, Ronald Hoffman, MD

Blood (2014) 124 (21): 819.

https://doi.org/10.1182/blood.V124.21.819.819

Published: 2014

Journal Articles

Imetelstat (GRN163L), a Telomerase Inhibitor Selectively Affects Malignant Megakaryopoiesis in Myeloproliferative Neoplasms (MPN)

Camelia Iancu-Rubin, PhD, Goar Mosoyan, Craig C Parker, Kevin Eng, PhD, Ronald Hoffman, MD

Blood (2014) 124 (21): 4582.

https://doi.org/10.1182/blood.V124.21.4582.4582

Published: 2014

Journal Articles

Combination Treatment with RG7112 and Pegylated Interferon α 2a Specifically Targets JAK2V617F Positive Progenitor Cells From Patients with Myeloproliferative Neoplasms.

Min Lu, PhD., Xiaoli Wang, MD, PhD, Goar Mosoyan, Yan Li, Ronald Hoffman, MD

Blood (2012) 120 (21): 2865.

https://doi.org/10.1182/blood.V120.21.2865.2865

Published: 2012

Journal Articles

Stromal Cells-Mediated Inhibition of Erythropoiesis Can Be Counteracted by Sotatercept (ACE-011), an Activin Receptor Type II (ActRIIA) Fusion Protein

Camelia Iancu-Rubin, Ph.D., Goar Mosoyan, Jiapeng Wang, PhD, Thomas Kraus, Ph.D., Ronald Hoffman, MD

Blood (2012) 120 (21): 1254.

https://doi.org/10.1182/blood.V120.21.1254.1254

Published: 2012

Journal Articles

Combination treatment in vitro with Nutlin, a small-molecule antagonist of MDM2, and pegylated interferon-α 2a specifically targets JAK2V617F-positive polycythemia vera cells

Min Lu, Xiaoli Wang, Yan Li, Joseph Tripodi, Goar Mosoyan, John Mascarenhas, Marina Kremyanskaya, Vesna Najfeld, Ronald Hoffman

Blood (2012) 120 (15): 3098–3105.

https://doi.org/10.1182/blood-2012-02-410712

Published: 2012

Journal Articles

Panobinostat (LBH589)-Mediated Acetylation of Tubulin Plays a Role in Megakaryocyte Maturation and Platelet Release

Camelia Iancu-Rubin, Ph.D., David Gajzer, MD, Goar Mosoyan, John Mascarenhas, MD, Ronald Hoffman, MD

Blood (2011) 118 (21): 704.

https://doi.org/10.1182/blood.V118.21.704.704

Published: 2011

NARROW

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Preclinical Development of a Cryopreservable Megakaryocyte Cell Product from Cord Blood Derived Hematopoietic Stem Cells

An IGF2BP3-Cdk9 Pathway Governs the Human Fetal-Adult Megakaryocyte Transition

Preclinical Development of a Cord Blood (CB)-Derived Hematopoietic Stem Cell (HSC) Product for Allogeneic Transplantation in Patients with Hematological Malignancies

A thrombopoietin receptor antagonist is capable of depleting myelofibrosis hematopoietic stem and progenitor cells

A Thrombopoietin Antagonist Is Capable of Affecting Stem and Progenitor Cells of Patients with Myelofibrosis

Imetelstat (GRN163L), a Telomerase Inhibitor Selectively Affects Malignant Megakaryopoiesis in Myeloproliferative Neoplasms (MPN)

Combination Treatment with RG7112 and Pegylated Interferon α 2a Specifically Targets JAK2V617F Positive Progenitor Cells From Patients with Myeloproliferative Neoplasms.

Stromal Cells-Mediated Inhibition of Erythropoiesis Can Be Counteracted by Sotatercept (ACE-011), an Activin Receptor Type II (ActRIIA) Fusion Protein

Combination treatment in vitro with Nutlin, a small-molecule antagonist of MDM2, and pegylated interferon-α 2a specifically targets JAK2V617F-positive polycythemia vera cells

Panobinostat (LBH589)-Mediated Acetylation of Tubulin Plays a Role in Megakaryocyte Maturation and Platelet Release

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American Society of Hematology

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American Society of Hematology

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