Skip to Main Content

Advertisement intended for health care professionals

Umbrella Alt Text
Cart
header search
Search
Skip Nav Destination

Issue Archive

Volume 116, Issue 3
July 22 2010
Issue Cover

Table of Contents

Inside Blood

HEMATOPOIESIS & STEM CELLS
Stem cells hold their breath
Gregor B. Adams
View Articletitled, Stem cells hold their breath
INSIDE BLOOD
Proteasome and HDAC: who's zooming who?
David McConkey
View Articletitled, Proteasome and HDAC: who's zooming who?
INSIDE BLOOD
Genomic imbalances in Hodgkin lymphoma
Ralf Küppers
View Articletitled, Genomic imbalances in Hodgkin lymphoma
RED CELLS & IRON
New era dawns on sickle cell pain
Samir K. Ballas
View Articletitled, New era dawns on sickle cell pain
VASCULAR BIOLOGY
NF-κB–induced chromatin remodeling regulates angiogenesis
Doruk Keskin,Raghu Kalluri
View Articletitled, NF-κB–induced chromatin remodeling regulates angiogenesis
VASCULAR BIOLOGY
Neutrophil CD44 rafts and rolls
Francis W. Luscinskas
View Articletitled, Neutrophil CD44 rafts and rolls

How I Treat

How I treat hemochromatosis
Paul C. Adams,James C. Barton
View Articletitled, How I treat hemochromatosis

Clinical Trials and Observations

Rituximab plus Peg-interferon-α/ribavirin compared with Peg-interferon-α/ribavirin in hepatitis C–related mixed cryoglobulinemia
CME
David Saadoun,Mathieu Resche Rigon,Damien Sene,Benjamin Terrier,Alexandre Karras,Laurent Perard,Yoland Schoindre,Brigitte Coppéré,François Blanc,Lucile Musset,Jean-Charles Piette,Michele Rosenzwajg,Patrice Cacoub
View Articletitled, Rituximab plus Peg-interferon-α/ribavirin compared with Peg-interferon-α/ribavirin in hepatitis C–related mixed cryoglobulinemia
Safety and efficacy of rituximab in patients with hepatitis C virus–related mixed cryoglobulinemia and severe liver disease
Clinical Trials & Observations
Antonio Petrarca,Luigi Rigacci,Patrizio Caini,Stefano Colagrande,Paolo Romagnoli,Francesco Vizzutti,Umberto Arena,Carlo Giannini,Monica Monti,Paolo Montalto,Marco Matucci-Cerinic,Alberto Bosi,Giacomo Laffi,Anna Linda Zignego
View Articletitled, Safety and efficacy of rituximab in patients with hepatitis C virus–related mixed cryoglobulinemia and severe liver disease
Pegylated interferon-α, ribavirin, and rituximab combined therapy of hepatitis C virus–related mixed cryoglobulinemia: a long-term study
Clinical Trials & Observations
Franco Dammacco,Felicia Anna Tucci,Gianfranco Lauletta,Pietro Gatti,Valli De Re,Vincenza Conteduca,Silvia Sansonno,Sabino Russi,Maria Addolorata Mariggiò,Maria Chironna,Domenico Sansonno
View Articletitled, Pegylated interferon-α, ribavirin, and rituximab combined therapy of hepatitis C virus–related mixed cryoglobulinemia: a long-term study
Genome-wide copy number analysis of Hodgkin Reed-Sternberg cells identifies recurrent imbalances with correlations to treatment outcome
Clinical Trials & Observations
Christian Steidl,Adele Telenius,Sohrab P. Shah,Pedro Farinha,Lorena Barclay,Merrill Boyle,Joseph M. Connors,Douglas E. Horsman,Randy D. Gascoyne
View Articletitled, Genome-wide copy number analysis of Hodgkin Reed-Sternberg cells identifies recurrent imbalances with correlations to treatment outcome
Supplemental data

Hematopoiesis and Stem Cells

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches
Ingrid G. Winkler,Valérie Barbier,Robert Wadley,Andrew C. W. Zannettino,Sharon Williams,Jean-Pierre Lévesque
View Articletitled, Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches
Supplemental data
Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation
Hyun-Jai Cho,Choon-Soo Lee,Yoo-Wook Kwon,Jae Seung Paek,Sun-Hee Lee,Jin Hur,Eun Ju Lee,Tae-Young Roh,In-Sun Chu,Sun-Hee Leem,Youngsoo Kim,Hyun-Jae Kang,Young-Bae Park,Hyo-Soo Kim
View Articletitled, Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation
Supplemental data

Immunobiology

Clonal expansion and TCR-independent differentiation shape the HIV-specific CD8+ effector-memory T-cell repertoire in vivo
Dirk Meyer-Olson,Brenna C. Simons,Joseph A. Conrad,Rita M. Smith,Louise Barnett,Shelly L. Lorey,Coley B. Duncan,Ramesh Ramalingam,Spyros A. Kalams
View Articletitled, Clonal expansion and TCR-independent differentiation shape the HIV-specific CD8<sup>+</sup> effector-memory T-cell repertoire in vivo
Supplemental data
Macrophage-specific gene functions in Spi1-directed innate immunity
e-blood
Anna Zakrzewska,Chao Cui,Oliver W. Stockhammer,Erica L. Benard,Herman P. Spaink,Annemarie H. Meijer
View Articletitled, Macrophage-specific gene functions in Spi1-directed innate immunity
Supplemental data

Lymphoid Neoplasia

Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma
Jiro Kikuchi,Taeko Wada,Rumi Shimizu,Tohru Izumi,Miyuki Akutsu,Kanae Mitsunaga,Kaoru Noborio-Hatano,Masaharu Nobuyoshi,Keiya Ozawa,Yasuhiko Kano,Yusuke Furukawa
View Articletitled, Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma
Supplemental data

Myeloid Neoplasia

Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
Clinical Trials & Observations
David Grimwade,Robert K. Hills,Anthony V. Moorman,Helen Walker,Stephen Chatters,Anthony H. Goldstone,Keith Wheatley,Christine J. Harrison,Alan K. Burnett,on behalf of the National Cancer Research Institute Adult Leukaemia Working Group
View Articletitled, Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
Supplemental data
The inositol phosphatase SHIP-1 is negatively regulated by Fli-1 and its loss accelerates leukemogenesis
Gurpreet K. Lakhanpal,Laura M. Vecchiarelli-Federico,You-Jun Li,Jiu-Wei Cui,Monica L. Bailey,David E. Spaner,Daniel J. Dumont,Dwayne L. Barber,Yaacov Ben-David
View Articletitled, The inositol phosphatase SHIP-1 is negatively regulated by Fli-1 and its loss accelerates leukemogenesis
Supplemental data

Phagocytes, Granulocytes, and Myelopoiesis

Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3
Katarzyna Barczyk,Jan Ehrchen,Klaus Tenbrock,Martina Ahlmann,Jessica Kneidl,Dorothee Viemann,Johannes Roth
View Articletitled, Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3
E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin αLβ2-mediated slow leukocyte rolling
Tadayuki Yago,Bojing Shao,Jonathan J. Miner,Longbiao Yao,Arkadiusz G. Klopocki,Kenichiro Maeda,K. Mark Coggeshall,Rodger P. McEver
View Articletitled, E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin α<sub>L</sub>β<sub>2</sub>-mediated slow leukocyte rolling
Supplemental data

Platelets and Thrombopoiesis

miR-28 is a thrombopoietin receptor targeting microRNA detected in a fraction of myeloproliferative neoplasm patient platelets
Michael Girardot,Christian Pecquet,Siham Boukour,Laurent Knoops,Augustin Ferrant,William Vainchenker,Stéphane Giraudier,Stefan N. Constantinescu
View Articletitled, miR-28 is a thrombopoietin receptor targeting microRNA detected in a fraction of myeloproliferative neoplasm patient platelets
Supplemental data

Red Cells, Iron, and Erythropoiesis

Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids
Divyanshoo R. Kohli,Yunfang Li,Sergey G. Khasabov,Pankaj Gupta,Lois J. Kehl,Marna E. Ericson,Julia Nguyen,Vinita Gupta,Robert P. Hebbel,Donald A. Simone,Kalpna Gupta
View Articletitled, Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids
Supplemental data

Transplantation

The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome–negative acute lymphoblastic leukemia in first and second complete remission
Clinical Trials & Observations
David I. Marks,Tao Wang,Waleska S. Pérez,Joseph H. Antin,Edward Copelan,Robert Peter Gale,Biju George,Vikas Gupta,Joerg Halter,H. Jean Khoury,Thomas R. Klumpp,Hillard M. Lazarus,Victor A. Lewis,Philip McCarthy,David A. Rizzieri,Mitchell Sabloff,Jeff Szer,Martin S. Tallman,Daniel J. Weisdorf
View Articletitled, The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome–negative acute lymphoblastic leukemia in first and second complete remission
Supplemental data
Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses
Christine Vogtenhuber,Christoph Bucher,Steven L. Highfill,Lisa K. Koch,Emily Goren,Angela Panoskaltsis-Mortari,Patricia A. Taylor,Michael A. Farrar,Bruce R. Blazar
View Articletitled, Constitutively active Stat5b in CD4<sup>+</sup> T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses
Supplemental data

Vascular Biology

NF-κB balances vascular regression and angiogenesis via chromatin remodeling and NFAT displacement
Arin B. Aurora,Dauren Biyashev,Yelena Mirochnik,Tetiana A. Zaichuk,Cristina Sánchez-Martinez,Marie-Ange Renault,Douglas Losordo,Olga V. Volpert
View Articletitled, NF-κB balances vascular regression and angiogenesis via chromatin remodeling and NFAT displacement
Supplemental data

Correspondence

A single-tube, sensitive multiplex method for screening of isocitrate dehydrogenase 1 (IDH1) mutations
Wen-Chien Chou,Yen-Ning Huang,Chi-Fei Huang,Mei-Hsuan Tseng,Hwei-Fang Tien
View Articletitled, A single-tube, sensitive multiplex method for screening of isocitrate dehydrogenase 1 (<em>IDH1</em>) mutations
Wnt3a nonredundantly controls hematopoietic stem cell function and its deficiency results in complete absence of canonical Wnt signaling
Tiago C. Luis,Brigitta A. E. Naber,Willem E. Fibbe,Jacques J. M. van Dongen,Frank J. T. Staal
View Articletitled, Wnt3a nonredundantly controls hematopoietic stem cell function and its deficiency results in complete absence of canonical Wnt signaling
Lentiviral vectors and transduction of human cancer B cells
Camille Lévy,Cecilia Frecha,Caroline Costa,Nicolas Rachinel,Gilles Salles,François-Loïc Cosset,Els Verhoeyen
View Articletitled, Lentiviral vectors and transduction of human cancer B cells
Response: Lentiviral vectors and transduction of human cancer B cells
Inbal Hazan-Halevy,David Harris,Zhiming Liu,Ping Li,Zeev Estrov
View Articletitled, Response: Lentiviral vectors and transduction of human cancer B cells
Tissue factor mutated at the allosteric Cys186-Cys209 disulfide bond is severely impaired in decrypted procoagulant activity
Wolfram Ruf,Henri H. Versteeg
View Articletitled, Tissue factor mutated at the allosteric Cys<sup>186</sup>-Cys<sup>209</sup> disulfide bond is severely impaired in decrypted procoagulant activity
Response: Cys186-Cys209 disulfide–mutated tissue factor does not equal cryptic tissue factor: no impairment in decryption of disulfide mutated tissue factor
Hema Kothari,L. Vijaya Mohan Rao,Usha R. Pendurthi
View Articletitled, Response: Cys<sup>186</sup>-Cys<sup>209</sup> disulfide–mutated tissue factor does not equal cryptic tissue factor: no impairment in decryption of disulfide mutated tissue factor

Other Departments

Peg-interferon α/ribavirin with and without rituximab for hepatitis C–related mixed cryoglobulinemia
CME
View Articletitled, Peg-interferon α/ribavirin with and without rituximab for hepatitis C–related mixed cryoglobulinemia
  • Cover Image

    Cover Image

    issue cover

    Changes in vasculature and proinflammatory mediators of pain in the dorsal skin of homozygous BERK mice expressing human sickle hemoglobin. A confocal Z-stack projection of the skin showing abnormal vasculature (CD31, bright green) with diminished vascular plexus and haphazardly oriented blood vessels. Intense punctate immunoreactivity of neuropeptides, substance P (SP, red), calcitonin gene-related peptide (CGRP, blue), and co-staining of SP and CGRP (magenta) is seen throughout the epidermis and dermis. See the article by Kohli et al on page 456.

  • PDF Icon PDF LinkFront Matter
  • PDF Icon PDF LinkTable of Contents
  • PDF Icon PDF LinkBack Matter
  • PDF Icon PDF LinkAdvertising
  • PDF Icon PDF LinkEditorial Board
All Issues

Advertisement intended for health care professionals

Licking the wound with procoagulant vesicles
Approaching Hypercalcemia in Monoclonal Gammopathy of Undetermined Significance: Insights from the iStopMM study
CAR T-cells in autoimmunity: game changer or stepping stone?
Long-Term Efficacy and Safety of Danicopan as Add-On Therapy to Ravulizumab or Eculizumab in PNH With Significant EVH
How I treat quantitative fibrinogen disorders

Advertisement intended for health care professionals

Advertisement intended for health care professionals

  • American Society of Hematology
  • 2021 L Street NW, Suite 900
  • Washington, DC 20036
  • TEL +1 202-776-0544
  • FAX +1 202-776-0545

ASH Publications

American Society of Hematology

Copyright 2024 by American Society of Hematology
 
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal

Advertisement intended for health care professionals