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Osteoclasts, the effector cells for bone resorption, can act as antigen-presenting cells and activate CD4⁺ and CD8⁺ T cells in vitro. The cover shows an image of osteoclasts with multiple cell nuclei and tartrate-resistant acid phosphatase activity, which appears as purple to dark red granules in the cytoplasm of the cells. See the article by Li et al on page 210.
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Licking the wound with procoagulant vesicles

Approaching Hypercalcemia in Monoclonal Gammopathy of Undetermined Significance: Insights from the iStopMM study

CAR T-cells in autoimmunity: game changer or stepping stone?

Long-Term Efficacy and Safety of Danicopan as Add-On Therapy to Ravulizumab or Eculizumab in PNH With Significant EVH

How I treat quantitative fibrinogen disorders

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Table of Contents

Inside Blood

Go long! A touchdown for factor VIII?

Throwing out the baby

Redeeming ristocetin

Review Article

Mast cells and the neurofibroma microenvironment

Clinical Trials and Observations

Cutaneous extranodal NK/T-cell lymphoma: a clinicopathologic study of 5 patients with array-based comparative genomic hybridization
Clinical Trials & Observations

Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis
Brief Report

XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments
Brief Report

Hematopoiesis and Stem Cells

Identification of an NK/T cell–restricted progenitor in adult bone marrow contributing to bone marrow– and thymic-dependent NK cells

Interaction of retinoic acid and scl controls primitive blood development

Immunobiology

Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia
Clinical Trials & Observations

Cross talk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4⁺ and CD8⁺ T cells

Processing and cross-presentation of individual HLA-A, -B, or -C epitopes from NY-ESO-1 or an HLA-A epitope for Melan-A differ according to the mode of antigen delivery

Lymphoid Neoplasia

In vivo targeting and growth inhibition of the A20 murine B-cell lymphoma by an idiotype-specific peptide binder

Telomere dysfunction-induced foci arise with the onset of telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells

Myeloid Neoplasia

AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2^V617F-independent overexpression of NF-E2

Red Cells, Iron, and Erythropoiesis

Hereditary spherocytosis and hereditary elliptocytosis: aberrant protein sorting during erythroblast enucleation
Brief Report

Thrombosis and Hemostasis

Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment

Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor
Clinical Trials & Observations

Transplantation

Comparison of human cord blood engraftment between immunocompromised mouse strains

SOCS3 regulates graft-versus-host disease

Vascular Biology

Induction, regulation, and biologic function of Axl receptor tyrosine kinase in Kaposi sarcoma

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ASH Publications

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Table of Contents

Inside Blood

Review Article

Clinical Trials and Observations

Cutaneous extranodal NK/T-cell lymphoma: a clinicopathologic study of 5 patients with array-based comparative genomic hybridization Clinical Trials & Observations

Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis Brief Report

XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments Brief Report

Hematopoiesis and Stem Cells

Immunobiology

Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia Clinical Trials & Observations

Lymphoid Neoplasia

Myeloid Neoplasia

Red Cells, Iron, and Erythropoiesis

Hereditary spherocytosis and hereditary elliptocytosis: aberrant protein sorting during erythroblast enucleation Brief Report

Thrombosis and Hemostasis

Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor Clinical Trials & Observations

Transplantation

Vascular Biology

Cover Image

Email alerts

ASH Publications

American Society of Hematology

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Cutaneous extranodal NK/T-cell lymphoma: a clinicopathologic study of 5 patients with array-based comparative genomic hybridization
Clinical Trials & Observations

Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis
Brief Report

XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments
Brief Report

Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia
Clinical Trials & Observations

Hereditary spherocytosis and hereditary elliptocytosis: aberrant protein sorting during erythroblast enucleation
Brief Report

Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor
Clinical Trials & Observations