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Issue Archive

Volume 2, Issue 2
May 2025
Blood Neoplasia Cover Image for Volume 2, Issue 2

Table of Contents

REVIEW ARTICLE

Thymic peptides in immune reconstitution and clinical outcome after allogeneic hematopoietic cell transplantation
Hannah Kunstek,Janneke Kieviet,Caroline Lindemans,Coco de Koning,Stefan Nierkens
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SYSTEMATIC REVIEW

Race and age disparities in randomized trials of acute myeloid leukemia: a systematic review and meta-analysis
Nathalie Loeb,Olivia Katsnelson,Anshika Jain,Parsa Tahvildar,Daniel Teitelbaum,Alejandro Garcia-Horton
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Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Prognostic impact of RDI of vincristine in patients with DLBCL receiving R-CHOP: a supplementary analysis of JCOG0601
Clinical Trials & Observations
Takahiro Nakashima,Tomotaka Suzuki,Ryunosuke Machida,Kazuyuki Shimada,Tsutomu Kobayashi,Dai Maruyama,Wataru Munakata,Shinsuke Iida,Ken Ohmachi,Tomohiro Kinoshita,Kiyoshi Ando,Hirokazu Nagai
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Supplemental data
Adult leukemia in Florida 2010-2019: diverse, aging population as an indicator for the United States
Clinical Trials & Observations
Ming S. Lee,Rebecca E. Kaiser,Christopher D. Armstrong,David B. Dukenik,Nancy S. Elliott,Raymond R. Balise,Justin M. Watts,Mikkael A. Sekeres,Erin N. Kobetz,Justin Taylor
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A phase 2 study of decitabine with or without carboplatin and arsenic trioxide in patients with MDS and AML
Clinical Trials & Observations
Patricia L. Kropf,Woonbok Chung,Raji Shameem,Lianchun Xiao,Curt Balch,Xuelin Huang,Jean-Pierre J. Issa
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Supplemental data
Improved survival with daratumumab-CyBorD compared with CyBorD as frontline therapy for AL amyloidosis
Clinical Trials & Observations
Binoy Yohannan,Matthew Rees,Morie A. Gertz,Angela Dispenzieri,Prashant Kapoor,Francis K. Buadi,David Dingli,Nelson Leung,Martha Q. Lacy,Suzanne R. Hayman,Wilson Gonsalves,Taxiarchis Kourelis,Joselle Cook,Moritz Binder,Mustaqeem Siddiqui,Yi Lin,Lisa Hwa,Michelle G. Rogers,Miriam Hobbs,Amie Fonder,Rahma Warsame,S. Vincent Rajkumar,Shaji K. Kumar,Eli Muchtar
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Supplemental data

LYMPHOID NEOPLASIA

Targeting transcription-replication conflicts using G-quadruplexes stabilizers in multiple myeloma
Laure Dutrieux,Sara Ovejero,Antoine Guillemin,Miss Leriem Zellagui,Elke De Bruyne,Catharina Muylaert,Lien Van Hemelrijck,Yea-Lih Lin,Elle Loughran,Armelle Choquet,Talha Magat,Soumya Bouchouika,Caroline Bret,Guilhem Requirand,Nicolas Robert,Laure Vincent,Guillaume Cartron,Charles Herbaux,Raphaël Rodriguez,Michel Cogné,Eric Rivals,Jean-Christophe Andrau,Alexandre David,Philippe Pasero,Jérôme Moreaux
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Supplemental data
Single-cell sequencing reveals shared clonal signatures in nonmalignant B and tumor cells in T-prolymphocytic leukemia
Caroline Hesselager,Ingrid Thörn,Millaray Marincevic,Claes Ladenvall,Jonas Almlöf,Sara Löfgren,Simone Weström,Helena Nord,Lesley-Ann Sutton,Lucia Cavelier,Panagiotis Baliakas,Rose-Marie Amini
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Supplemental data
A feedforward loop between ACLY and MYC supports T-ALL progression in vivo
Victoria da Silva-Diz,Amartya Singh,Maya Aleksandrova,Oekyung Kim,Christopher Thai,Olga Lancho,Patricia Renck Nunes,Hayley Affronti,Alexia Martínez de Paz,Steven Z. Josefowicz,Xiaoyang Su,Kathryn E. Wellen,Daniel Herranz
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Supplemental data
Real-world treatment patterns and clinical outcomes in patients with follicular lymphoma: a SEER-Medicare analysis
Dai Chihara,Shibing Yang,Savreet Bains Chawla,Guihua Zhang,Anthony Wang,Junhua Yu,Donald Arnette,Fernando Rivas Navarro,Julie Blaedel,Alex Mutebi
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Supplemental data
Discovery of a novel class NSD2 inhibitor for multiple myeloma with t(4;14)+
Sae Matsuoka,Naoki Osada,Hirokazu Kubota,Ko Kikuzato,Hiroo Koyama,Takeshi Sonoda,Akiko Idei,Minoru Yoshida,Masaki Kikuchi,Takashi Umehara,Chiduru Watanabe,Teruki Honma,Hiroshi Yasui,Sho Ikeda,Naoto Takahashi,Hideki Nakasone,Jiro Kikuchi,Yusuke Furukawa
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Supplemental data
Retrospective evaluation of R-EPOCH in the frontline treatment of adult patients with PTLD after solid organ transplant
Brian Cuzzo,Maegan Ford,Saagar Jain,Hua-Jay Cherng,Evelyn Orlando,Patrick Gould,Amy Song,Benjamin May,Yuxuan Chen,Govind Bhagat,Andrew H. Lipsky,Barbara Pro,Jennifer E. Amengual
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MYELOID NEOPLASIA

Clinical correlation and prognostic impact of cytogenetic clone size for myelodysplastic syndromes/neoplasm
Zhuoer Xie,Najla Al Ali,Ling Zhang,Peter Papenhausen,Virginia Olivia Volpe,Onyee Chan,Andrew Kuykendall,Seongseok Yun,Alison Walker,Kendra Sweet,Jeffrey E. Lancet,Eric Padron,David A. Sallman,Rami S. Komrokji
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Supplemental data
Characterization of fusion transcripts in AML without recurrent genetic abnormalities unravels new putative fusion genes
Francesca Guijarro,Sandra Cabezas,Marc Dabad,Alex Bataller,Cristina López,Sandra Castaño-Díez,Carlos Jiménez-Vicente,Albert Cortés-Bullich,Marta Garrote,Jose R. Álamo,Miriam Prieto,Aina Cardús,Marta Pratcorona,Maria Rozman,Marta Aymerich,Neus Villamor,Dolors Colomer,Jordi Morata,Anna Esteve-Codina,Sílvia Beà,Dolors Costa,Marina Díaz-Beyá,Monica López-Guerra,Jordi Esteve
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Supplemental data
Driver mutations in myeloid and lymphoid cells point to multipotent progenitor origin of diverse histiocytic neoplasms
Astrid G. S. van Halteren,Paul G. Kemps,Jelske Forma-Borst,Yanling Xiao,Maud A. J. I. van den Oetelaar,Nina U. Gelineau,Robert M. Verdijk,Lydia E. Vos,Koen D. Quint,Cor van den Bos,Eli L. Diamond,Jan A. M. van Laar
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Supplemental data
Multiplex gene editing models of del(7q) reveal combined CUX1 and EZH2 loss drives clonal expansion and drug resistance
Matthew R. M. Jotte,Angela Stoddart,Tanner C. Martinez,Raven Moten,Yuqing Xue,Molly K. Imgruet,Hunter Blaylock,Henna S. Nam,Bonnie Hu,Jermaine Austin,Ningfei An,Saira Khan,Sandeep K. Gurbuxani,Megan E. McNerney
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RESEARCH LETTERS

Clonal composition of karyotypically normal AML at diagnosis is not affected by the microenvironment
Monika M. Toma,Adam Karami,Margaret Nieborowska-Skorska,Tomasz Skorski
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New leads to enhance tagraxofusp efficacy in pDC-AML
Morgane Boichut,Margaux Poussard,Xavier Roussel,Imane Belakri,Sabeha Biichlé,Maxime Fredon,Florian Renosi,Romain Boidot,Olivier Adotevi,Christopher Brooks,Francine Garnache-Ottou,Fanny Angelot Delettre
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Supplemental data
A novel 3-way translocation involving ETV6::IL3 drives AML with eosinophilia
Ariel Siegel,Joseph Tripodi,Dianna Hardatt,Brianna Kelly,Sebastian El Ghaity-Beckley,Michelle Becker,Brenton Francisco,Kayleen Bailey,Bruce Petersen,Douglas Tremblay,Jonathan Feld,Hannah Levavi,Marina Kremyanskaya,Alla Keyzner,Bridget K. Marcellino,Christian Salib,Amy S. Duffield,John Mascarenhas,Vesna Najfeld,Alan H. Shih
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Supplemental data
Short-duration infusion obinutuzumab with venetoclax in chronic lymphocytic leukemia: a prospective observational study
Priyanka Pullarkat,Matthew Lei,Robert Redd,Ruchi Rana,Uvette Lou,Mark Sorial,Brenna Rowen,E. Bridget Kim,Andrea Medrano,J. Erika Haydu,Jeffrey Barnes,Ephraim Hochberg,P. Connor Johnson,Ronald Takvorian,Julia Lynch,Emily Patterson,Katherine Thorp,Maryanne Sherburne,Brianne McGree,Josie Ford,Ronald Nemec,Catherine Cho,Jeremy Abramson,Jacob D. Soumerai
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Outcomes for ruxolitinib only versus combination with interferon in treating patients with myelofibrosis
Katie Erdos,Aya Alshareef,Richard T. Silver,Joseph M. Scandura,Ghaith Abu-Zeinah
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Supplemental data
Prospective clinical trials of venetoclax and hypomethylating agents for relapsed BPDCN
Clinical Trials & Observations
Naveen Pemmaraju,Luan Hai Phan,Geoffrey Fell,Marlise R. Luskin,Mahesh Swaminathan,Sherry Pierce,Courtney DiNardo,Abhishek Maiti,Marina Konopleva,Andrew A. Lane
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Response and outcomes of patients with IDH1/2- mutated accelerated/blast-phase myeloproliferative neoplasms
Leah A. Goldberg,James J. Yoon,Hannah Johnston,Marta B. Davidson,Alexa Siddon,Rory M. Shallis,Evan C. Chen,Madelyn Burkart,Timothy S. Oh,Sunil G. Iyer,Ellen Madarang,Chandrasekar Muthiah,Joshua Kassner,Raajit K. Rampal,Guru Subramanian Guru Murthy,Terrence Bradley,Yasmin Abaza,Jacqueline S. Garcia,Vikas Gupta,Kristen M. Pettit,Olatoyosi Odenike,John F. Cursio,Anand A. Patel
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Supplemental data
Genomic landscape and clonal architecture in pediatric myeloid neoplasms with chromosome 7 deletions
Tamara Westover,Michael P. Walsh,Sherif Abdelhamed,Emily Xiong,Jing Ma,Guangchun Song,Melvin E. Thomas, III,Masayuki Umeda,Jamie L. Maciaszek,Jasmine C. Wong,Astrid Wintering,Lu Wang,Peter D. Emanuel,Mignon L. Loh,Sarah K. Tasian,Elliot Stieglitz,Jason R. Schwartz,Kevin M. Shannon,Jeffery M. Klco
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ERRATA

Uemura Y, Yamamoto M, Ishimura M, et al. JAK1/2 inhibitor ruxolitinib for the treatment of systemic chronic active Epstein-Barr virus disease: a phase 2 study. Blood Neoplasia. 2025;2(1):100053.
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Moura PL, Nannya Y, Aliouat A, et al. Competition of dual SF3B1mt clones in MDS-RS is associated with distinct RNA mis-splicing in hematopoietic stem cells. Blood Neoplasia. 2024;1(2):100011.
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  • Cover Image

    Cover Image

    issue cover

    Circos plot showing the fusion transcripts found in a cohort of 109 patients with acute myeloid leukemia without recurrent genetic abnormalities. Fusion transcripts are classified as Tier-1 (red), Tier-2 (purple), Tier-3 (orange), and Tier-4 (green). See the article by Guijarro et al.

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