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First Edition

Research Article September 1 2025
Inferior Survival in Double Refractory Large B-cell Lymphoma Eligible for third-line CD19 CAR T-cell Therapy
Chathuri Abeyakoon,Sita Bhella,Katrina Hueniken,Rachel Aitken,Carmel Waldron,Anca Prica,Vishal Kukreti,Robert Kridel,Abi Vijenthira,Christine Chen,Chloe Yang,Richard Tsang,David Hodgson,Danielle Rodin,Nauman Malik,Woodrow Wells,Michael Crump,John Kuruvilla
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Research Article August 25 2025
Application of the International Working Group MDS Molecular Taxonomy Classes to a Single Institution Cohort
Rohiverth Guarecuco,Lisa Yuen,Maxwell Roth,Brandon J Aubrey,Andrew M Brunner,Robert P Hasserjian
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Research Article August 25 2025
Final Safety and Efficacy Results from a Phase 1/2 Study of Tagraxofusp, a CD123-Targeted Therapy, for Myelofibrosis
Abdulraheem Yacoub,Haris Ali,Vikas Gupta,Eunice S. Wang,Mrinal M. Patnaik,Gary J. Schiller,Minakshi Taparia,Tariq I. Mughal,Ross Lindsay,Antonio Galleu,Ira Gupta,Naveen Pemmaraju
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Research Article August 25 2025
Predicting Secondary Myeloid Neoplasms in Acquired Aplastic Anemia Using Machine Learning Models
Ahmet Celal Toprak,Mutlu Mete,Julia J. Shi,Daria V. Babushok,Carmelo Gurnari,Jaroslaw P. Maciejewski,Zoe Bass,Zehra Tombul,Carlos. I.A. Santos,Munevver N. Duran,Hussein Awada,Ibrahim Ibrahim,Alper Olcal,Yusuf Ozcan,Leslie Guerrero,Julio Alvarenga Thiebaud,Taha Bat
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Research Article August 25 2025
Analyses of transplantation outcomes for adult patients with mixed-phenotype acute leukemia
Tomoyasu Jo,Tadakazu Kondo,Shohei Mizuno,Shinichi Kako,Noriko Doki,Naoyuki Uchida,Masatsugu Tanaka,Tetsuya Nishida,Takahiro Fukuda,Masashi Sawa,Yoshinobu Kanda,Satoru Takada,Yuta Hasegawa,Yuta Katayama,Satoshi Yoshihara,Koji Kawamura,Marie Ohbiki,Yoshiko Atsuta,Masamitsu Yanada,Yasuyuki Arai
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Research Article August 19 2025
Second Malignancies among Older Patients with Classical Myeloproliferative Neoplasms Treated with Ruxolitinib
Rong Wang,Jessica M. Stempel,Rory M. Shallis,Scott F. Huntington,Amer M. Zeidan,Natalia Neparidze,Mengyang Di,Jan Philipp Bewersdorf,Lourdes Mendez,Xiaomei Ma,Nikolai A. Podoltsev
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Research Article August 19 2025
Posttransplant Rituximab Exposure and Risk of PTLD in Solid Organ Transplant Recipients with EBV DNAemia
Evelyn H. Orlando,Patrick Gould,Brian Cuzzo,Maegan Ford,Yuxuan Chen,Alexander Sanjurjo,Saagar Jain,Benjamin May,Demetra Tsapepas,Rebecca J. Leeman-Neill,Govind Bhagat,Geoffrey K. Dube,Heather Morris,Selim Arcasoy,Farhana Latif,Ersilia M. DeFilippis,Mercedes Martinez,Gene Y. Im,Meaghan M. Phipps,Marcus R. Pereira,Paul K. Sue,Manuela Orjuela-Grimm,Andrew H. Lipsky,Ahmed Sawas,Ran Reshef,Barbara Pro,Hua-Jay J. Cherng,Jennifer E. Amengual
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Research Article August 19 2025
Azanucleoside treatment leads to B cell precursor acute lymphoblastic leukemia (BCP ALL)
Vijay Negi,Ryan Bertoli,Olivia Tuckey,Yuelin Jack Zhu,Robert L. Walker,Michael J. Difilippantonio,James H. Doroshow,Paul S. Meltzer,Peter D. Aplan
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Research Article August 5 2025
Disparities in Real-World Treatment Patterns of Hypomethylating Agents Among Patients with Myelodysplastic Syndromes in the US
Sudipto Mukherjee,Weichuan Dong,Aaron T. Gerds,Hetty E. Carraway,Abhay Singh,Anjali S. Advani,Moaath K. Mustafa Ali,John Molina J,Sophia Balderman,Akriti Jain,Paolo Caimi,Faiz Anwer,Mikkael A. Sekeres,Siran M. Koroukian
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Research Article August 4 2025
Ivosidenib or venetoclax combined with hypomethylating agents in IDH1-mutated acute myeloid leukemia: a real-world study
Curtis A. Lachowiez,B. Douglas Smith,Alexander Joseph Ambinder,Gary Binder,Anne Angiolillo,Ravi Potluri,Eros Papademetriou,Thomas W. LeBlanc
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Research Article August 4 2025
B-cell-Specific Wwox Deletion Promotes Plasmablastic Tumor Development and Pro-Inflammatory Signatures in Myeloma Model
Tabish Hussain,Matthew D. Bramble,Bin Liu,Martin C. Abba,Marta Chesi,C. Marcelo Aldaz
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Research Article August 4 2025
Orally Available Decitabine Prodrug OR-2100 induces Mitotic Perturbation for The Treatment Of Double-Hit Lymphoma
Keisuke Kidoguchi,Hiroshi Ureshino,Yuta Yamamoto,Ryo Yanagiya,Yuki Kurahashi,Yuki Fukuda-Kurahasi,Yumeka Mine,Shigehisa Aoki,Kazutaka Nakashima,Hiroaki Miyoshi,Koichi Ohshima,Atsushi Kawaguchi,Shinya Kimura
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Research Article August 4 2025
Hypertension in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in ALPINE: A Secondary Analysis
June-Wha Rhee,Nicole Lamanna,Wassim Aldairy,Lipeng Chen,Jun Zhang,Dulce Ramirez,William B. White
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Research Article August 4 2025
MNT: a new target for AML
Karla C Fischer,Veronique Litalien,Sarah T Diepstraten,Michelle Jahja,Fiona C Brown,Gemma L Kelly,Andrew H Wei,Suzanne Cory
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Brief Report August 4 2025
Neutrophil-mediated trogocytosis as a new mechanism of action of daratumumab
Mauro Lorenzo-Mohamed,Carla Vicario-Bueno,Andrea Díaz-Tejedor,Marta González-Rodríguez,Bárbara Castellanos,Janet Sotolongo-Ravelo,Laura San-Segundo,Lorena González-Méndez,Montserrat Martín-Sánchez,Mercedes Garayoa,Teresa Paíno
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Brief Report August 4 2025
A single nucleotide polymorphism in the TCL1A promoter is not protective in patients with germline RUNX1-FPD
Amra Kajdic,Natalie T. Deuitch,Ana Catarina Menezes,Martha Kirby,Ursula Harper,Shawn Chong,Kathleen Craft,Joie Davis,Raman Sood,David J. Young,Erica Bresciani,Paul P. Liu
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Research Article August 4 2025
Bendamustine switches TNF receptor superfamily signal from a survival to a death signal in B-cell lymphomas
Kensuke Nakao,Hiroshi Arima,Yui Arakawa,Tomoyasu Jo,Yujuan Guo,Iroha Morita,Tomohiro Taya,Toshio Kitawaki,Akifumi Takaori-Kondo,Momoko Nishikori
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Brief Report August 4 2025
Loss of STAT3 in Acute Myeloid Leukemia Favors Tissue Infiltration Linked to CXCR4 Signaling
Bernhard Zdársky,Sophie Edtmayer,Agnieszka Witalisz-Siepracka,Stefanie Weiss,Stefanie Boigenzahn,Kerstin Heindl,Safia Zahma,Balázs Győrffy,Richard Moriggl,Dagmar Stoiber
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Research Article July 25 2025
Omacetaxine and venetoclax in relapsed/refractory acute myeloid leukemia or myelodysplastic syndrome with mutant RUNX1
Courtney D. DiNardo,Wei-Ying Jen,Guillermo Montalban-Bravo,Xuemei Wang,Sanam Loghavi,Sravanthi Lavu,Nicholas J. Short,Kelly Chien,Ghayas C. Issa,Naveen Pemmaraju,Musa Yilmaz,Michael Andreeff,Gautam Borthakur,Tapan M. Kadia,Naval G. Daver,Guillermo Garcia-Manero,Christopher P. Mill,Xiaoping Su,Warren Fiskus,Kapil N. Bhalla
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Review Article July 25 2025
How to drug a leukemic stem cell: deciphering heterogeneity for better specificity
Alice Worker,Nicholas Jinks,Peter Woodmancy,Claire Seedhouse,Sophie G Kellaway
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Brief Report July 25 2025
A Prospective Study of Prophylactic Dexamethasone with Glofitamab in Relapsed/Refractory Large B-cell Lymphoma
J. Erika Haydu,Matthew M. Lei,Robert A. Redd,Jeffrey A. Barnes,Elijah P. Darnell,Ephraim P. Hochberg,P. Connor Johnson,Ronald W. Takvorian,James I. Weitzman,Elliot C. Woods,Tiffany L. Hurvitz,Courtney D. Lafranchi,Patricia Livingstone,Julia M. Lynch,Emily N. Patterson,Jack E. Malespini,Brianne M. McGree,Alexa O. Santilli,Katherine A. Thorp,Maryanne M. Sherburne,Lindsay B. Wardrop,Uvette Y. Lou,Mark N. Sorial,Catherine Cho,Josie Ford,Ronnie Nemac,Jacob D. Soumerai,Jeremy S. Abramson.
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Brief Report July 25 2025
Eμ-TCL1 mice with conditional human BCL2 knock-in as novel B cell lymphoma model for studying venetoclax effects in vivo
Ismini Halmer,Daniela Asslaber,Laura Beckmann,Gero Knittel,H. Christian Reinhardt,Hamid Kashkar,Michael Hallek,Jens Löber,Björn Chapuy,Alexander Egle,Günter Krause,Alexandra da Palma Guerreiro,Lukas P. Frenzel
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Brief Report July 25 2025
SRSF2 Mutations in CCUS, MDS and AML: A Cross-Entity Study
Sandra Huber,Sarah Ochmann,Stephan Hutter,Veronika Ecker,Manja Meggendorfer,Gregor Hoermann,Torsten Haferlach,Claudia Haferlach,Isolde Summerer
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Research Article July 25 2025
Targeting CDK9 inhibits the growth of KMT2A rearranged infant leukemia and demonstrates synergy with menin inhibition
Ritul Sharma,Chunfen Zhang,Ravi Shah,Melanie M. Frigault,Amy J. Johnson,David Spencer Mangum,Luke D. Maese,Norman J Lacayo,Aru Narendran
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Research Article July 25 2025
Shelter in place: Live CLL cells inside the bone marrow fibroblasts and its implication in residual disease persistence
Pin Lu,Carrie A Franzen,Aldana Vistarop,Andrey Efimov,SK Abrar Shahriyar,Shengchun Wang,Shilpa Rao,Marcus Messmer,Shazia Nakhoda,Edna Cukierman,Shuo Ma,Janusz Franco-Barraza,Juehua Gao,Y. Lynn Wang
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Brief Report July 22 2025
Three-year follow-up of low-dose, early-start gilteritinib maintenance in posttransplant patients with R/R FLT3mut AML
Toshiki Terao,Ken-ichi Matsuoka,Takumi Kondo,Yoshinobu Maeda
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Brief Report July 16 2025
IgA or IgM MGUS less than 1.0 g/dL is at Low Risk of Progression to Neoplasm
Ashok P Pai,Lue-Yen Tucker,David M Baer
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Brief Report June 30 2025
Posttranscriptional activity of eIF4E contributes to HoxA9-driven leukemogenesis
Fang Zhou,Biljana Culjkovic-Kraljacic,Christian Bach,Li Feng,Yuta Mishima,Katherine L. B. Borden,Daniel G Tenen
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Research Article June 30 2025
Intensive Chemotherapy vs. Venetoclax/Hypomethylating Agents for Patients Aged 60-75 with Favorable, NPM1-mutated AML
Andrew Zale,Venkata Preetam Sandeep Kaduluri,Jonathan Webster,Mark Levis,Ivana Gojo,Amy DeZern,Gabriel Ghiaur,Lukasz Gondek,William Dalton,Theodoros Karantanos,Tania Jain,Gabrielle Prince,Richard Jones,B. Douglas Smith,Alexander Ambinder
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Review Article June 19 2025
Current Landscape of Frontline and Relapsed Follicular Lymphoma Trials
Lawrence Cheng Kiat Ng,Carla Casulo
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Research Article June 9 2025
Correlates of Organ Damage in Advanced Systemic Mastocytosis Patients Enrolled in Clinical Trials of Avapritinib
Emily C. Liang,Cecelia Perkins,Rong Lu,Hongliang Shi,Saša Dimitrijević,Justin Abuel,Cheryl Langford,Parveen Abidi,Lenn Fechter,William Shomali,Jason Gotlib
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Research Article June 3 2025
V-FAST: A phase 1b master trial to investigate CPX-351 combined with targeted agents in adults with newly diagnosed AML
Vinod A. Pullarkat,Mark Levis,James McCloskey,Gabriel N. Mannis,Stephen A. Strickland,Amir T. Fathi,Tara L. Lin,Vijaya R. Bhatt,Thuva Vanniyasingam,Divya Chakravarthy,Yana Lutska,Stefan Faderl,Ronald S. Cheung,Harry P. Erba
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Research Article June 3 2025
Targeting scavenger receptor class B type 1 with a bioinspired ligand induces apoptosis or ferroptosis in AML
Adam Y. Lin,Jonathan S. Rink,Eva Yang,Sara Small,Jessica J. Gerber,Taylor J Zak,Jessica Altman,Yasmin Abaza,Leonidas C. Platanias,Leo I Gordon,C. Shad Thaxton
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Research Article May 11 2025
A Comparative Assessment of Molecular-Based Prognostic Models in CMML
Luis E. Aguirre,Najla Al Ali,Somedeb Ball,Akriti G. Jain,David Sallman,Andrew Kuykendall,Alison R. Walker,Kendra Sweet,Jeffrey E. Lancet,Eric Padron,Rami S. Komrokji
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Research Article April 16 2025
Olfactory Receptors as Tumor Suppressors in Cutaneous T-Cell Lymphoma via p38γ Pathway Modulation
Xu Hannah Zhang,Hongzhi Li,Jack Hsiang,Ching-Hong Chen,Sangkil Nam,Henry Wong,Xiwei Wu,Weidong Hu,Jack Shively,Steven T. Rosen
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