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Journal Articles

The role of AGK in thrombocytopoiesis and possible therapeutic strategies

Haojie Jiang, Zhuo Yu, Nan Ding, Mina Yang, Lin Zhang, Xuemei Fan, Yuan Zhou, Qiang Zou, Jian Hou, Junke Zheng, Lei Zhang, Yanyan Xu, Junling Liu

Blood (2020) 136 (1): 119–129.

https://doi.org/10.1182/blood.2019003851

Published: 2020

Includes: Supplemental data

Journal Articles

Aromatase is a novel neosubstrate of cereblon responsible for immunomodulatory drug–induced thrombocytopenia

Taro Tochigi, Toshihiro Miyamoto, Kiwamu Hatakeyama, Teppei Sakoda, Daisuke Ishihara, Hidetoshi Irifune, Takahiro Shima, Koji Kato, Takahiro Maeda, Takumi Ito, Hiroshi Handa, Koichi Akashi, Yoshikane Kikushige

Blood (2020) 135 (24): 2146–2158.

https://doi.org/10.1182/blood.2019003749

Published: 2020

Includes: Supplemental data

Journal Articles

Megakaryocyte migration defects due to nonmuscle myosin IIA mutations underlie thrombocytopenia in MYH9 -related disease

Kasturi Pal, Roberta Nowak, Neil Billington, Rong Liu, Arit Ghosh, James R. Sellers, Velia M. Fowler

Blood (2020) 135 (21): 1887–1898.

https://doi.org/10.1182/blood.2019003064

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

Blood (2019) 134 (21): 1847–1858.

https://doi.org/10.1182/blood.2019000185

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

Adrian R. Wilkie, PhD, Leila J. Noetzli, PhD, Genevieve Couldwell, Anthony R. Sciaudone, Anjana Ray, PhD, Kellie R. Machlus, PhD, Joseph E. Italiano, Jr., BS, PhD

Blood (2019) 134 (Supplement_1): 721.

https://doi.org/10.1182/blood-2019-130803

Published: 2019

Journal Articles

M6PR-Specific Targeting of Lysosomal Heparanase Regulates Platelet Hemostatic Function in Mice

Nathan Eaton, BS, Caleb Drew, BS, Theresa A. Dlugi, PhD, Karin M. Hoffmeister, MD, Hervé Falet, PhD

Blood (2019) 134 (Supplement_1): 1059.

https://doi.org/10.1182/blood-2019-129075

Published: 2019

Journal Articles

The Mir-99b/Let-7e/Mir-125a cluster Is Associated with Platelet Count and Mean Platelet Volume and Regulates Megakaryocyte Proplatelet Formation

Seema Bhatlekar, Emilia A Tugolukova, B.S., Paul F. Bray, MD

Blood (2019) 134 (Supplement_1): 1065.

https://doi.org/10.1182/blood-2019-131667

Published: 2019

Journal Articles

Strategies for Analysis of Novel Molecular Variants in the RUNX1 Gene As a Cause of Familial Platelet Disorder with Predisposition to Acute Myeloid Leukemia (FPD/AML)

Veronica Palma-Barqueros, MSc, Jf Ruiz-Pividal, MSc, Jose Maria Bastida, MD PhD, Natalia Bohdan, MJ Lopez-Andreu, PhD, Raul Teruel-Montoya, PhD, Ana Isabel Antón, PhD, Francisca Ferrer Marin, MD PhD, Jose Padilla, Rosa Cifuentes-Riquelme, A Marín-Quilez, MSc, Marta Martín Izquierdo, MSc, Rocio Benito, PhD, Vicente Vicente, MD PhD, Jesus Maria . Hernández-Rivas, MD, José Ramón González-Porras, MD PhD, Jose Rivera, PhD, Maria Luisa Lozano, MD PhD

Blood (2019) 134 (Supplement_1): 2359.

https://doi.org/10.1182/blood-2019-128736

Published: 2019

Journal Articles

ANKRD26 Coding Variants Presenting with Giant Platelets and a Predisposition to Myeloid Neoplasia

Teodora Kuzmanovic, Bhumika J. Patel, MD, Jibran Durrani, Hassan Awada, MD, Cassandra M Kerr, MS, Bartlomiej P. Przychodzen, Samuel Li, BA, Seth J. Corey, MD, Sudipto Mukherjee, MD PhD MPH, Anjali S. Advani, MD, Aziz Nazha, MD, Aaron T. Gerds, MD MS, Hetty E. Carraway, MD MBA, Thomas Laframboise, PhD, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD

Blood (2019) 134 (Supplement_1): 4233.

https://doi.org/10.1182/blood-2019-130520

Published: 2019

Journal Articles

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Kamaleldin E Elagib, PhDMBBS, Ashton Brock, PhD, Goar Mosoyan, Cara Clementelli, Lorrie L Delehanty, BS, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, PhD, Stephen Morris, MD, Koji Eto, MD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD

Blood (2019) 134 (Supplement_1): 3250.

https://doi.org/10.1182/blood-2019-129049

Published: 2019

Journal Articles

Autoantibody Mediated Desialylation Impairs Human Thrombopoiesis and Platelet Life Span

Irene Marini, Jan Zlamal, Lisann Pelzel, Wolfgang Bethge, Christoph Faul, MD, Ursula Holzer, PD Dr. MD, Karina Althaus, Tamam Bakchoul, Prof. Dr.

Blood (2019) 134 (Supplement_1): 2346.

https://doi.org/10.1182/blood-2019-131725

Published: 2019

Journal Articles

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

Qiu-Sha Huang, Jing Xue, Chen-Cong Wang, Ya-Zhen Qin, Lan-Ping Xu, Kaiyan Liu, Xiao-Jun Huang, MD, Xiao-Hui Zhang

Blood (2019) 134 (Supplement_1): 218.

https://doi.org/10.1182/blood-2019-126384

Published: 2019

Journal Articles

Disrupted filamin A/α IIb β 3 interaction induces macrothrombocytopenia by increasing RhoA activity

Alessandro Donada, Nathalie Balayn, Dominika Sliwa, Larissa Lordier, Valentina Ceglia, Francesco Baschieri, Cyril Goizet, Rémi Favier, Lucie Tosca, Gérard Tachdjian, Cecile V. Denis, Isabelle Plo, William Vainchenker, Najet Debili, Jean-Philippe Rosa, Marijke Bryckaert, Hana Raslova

Blood (2019) 133 (16): 1778–1788.

https://doi.org/10.1182/blood-2018-07-861427

Published: 2019

Includes: Supplemental data

Journal Articles

αIIb(R990W), a Gain-of Function Mutation of αIIbβ3, Knock-in Mice Show Moderately Impaired Thrombopoiesis

Keigo Akuta, Kazunobu Kiyomizu, MD, Hirokazu Kashiwagi, Shinji Kunishima, PhD, Fumiaki Banno, Koichi Kokame, Nobuko Nishiura, Hisashi Kato, MD PhD, Shigenori Honda, MD, Yuzuru Kanakura, MD PhD, Toshiyuki Miyata, Yoshiaki Tomiyama, MD

Blood (2018) 132 (Supplement 1): 3743.

https://doi.org/10.1182/blood-2018-99-115953

Published: 2018

Journal Articles

Platelet Biogenesis in the Lung Circulation

Mark Looney

Blood (2018) 132 (Supplement 1): SCI-22.

https://doi.org/10.1182/blood-2018-99-109544

Published: 2018

Journal Articles

CCL5 Enhances Megakaryocyte Differentiation and Development

Leila Noetzli, PhD, Somayje Parvin, Elisabeth Battinelli, MD PhD, Kellie Machlus, PhD

Blood (2018) 132 (Supplement 1): 522.

https://doi.org/10.1182/blood-2018-99-117518

Published: 2018

Journal Articles

ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia

Markus Spindler, Judith M. M. van Eeuwijk, Yvonne Schurr, Paquita Nurden, Bernhard Nieswandt, David Stegner, Annegret Reinhold, Markus Bender

Blood (2018) 132 (6): 635–646.

https://doi.org/10.1182/blood-2018-01-829259

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Blood (2017) 130 (25): 2774–2785.

https://doi.org/10.1182/blood-2017-05-784413

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Exogenously Added Cofilin Increases Ex Vivo Production of Functional Platelets By Stimulating Proplatelet Formation

Munetada Haruyama, Akira Niwa, MD, PhD, Megumu K Saito, MD, PhD, Tatsutoshi Nakahata, MD, PhD

Blood (2017) 130 (Supplement 1): 3606.

https://doi.org/10.1182/blood.V130.Suppl_1.3606.3606

Published: 2017

Journal Articles

Aberrant Level of Estrogen Correlates with Defective Thrombopoiesis during Pregnancy in Patients with Immune Thrombocytopenia

Qi Chen, Xiao Liu, Jing-Zhong Zhao, Chen-Cong Wang, Ya-Nan Wang, Jing Xue, Jia-Min Zhang, MD, Xiao-Lu Zhu, Yun He, Qian-Ming Wang, Hai-Xia Fu, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang, MD, Xiaohui Zhang, MD

Blood (2017) 130 (Supplement 1): 1047.

https://doi.org/10.1182/blood.V130.Suppl_1.1047.1047

Published: 2017

NARROW

The role of AGK in thrombocytopoiesis and possible therapeutic strategies

Aromatase is a novel neosubstrate of cereblon responsible for immunomodulatory drug–induced thrombocytopenia

Megakaryocyte migration defects due to nonmuscle myosin IIA mutations underlie thrombocytopenia in MYH9 -related disease

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

M6PR-Specific Targeting of Lysosomal Heparanase Regulates Platelet Hemostatic Function in Mice

The Mir-99b/Let-7e/Mir-125a cluster Is Associated with Platelet Count and Mean Platelet Volume and Regulates Megakaryocyte Proplatelet Formation

Strategies for Analysis of Novel Molecular Variants in the RUNX1 Gene As a Cause of Familial Platelet Disorder with Predisposition to Acute Myeloid Leukemia (FPD/AML)

ANKRD26 Coding Variants Presenting with Giant Platelets and a Predisposition to Myeloid Neoplasia

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Autoantibody Mediated Desialylation Impairs Human Thrombopoiesis and Platelet Life Span

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

Disrupted filamin A/α IIb β 3 interaction induces macrothrombocytopenia by increasing RhoA activity

αIIb(R990W), a Gain-of Function Mutation of αIIbβ3, Knock-in Mice Show Moderately Impaired Thrombopoiesis

Platelet Biogenesis in the Lung Circulation

CCL5 Enhances Megakaryocyte Differentiation and Development

ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Exogenously Added Cofilin Increases Ex Vivo Production of Functional Platelets By Stimulating Proplatelet Formation

Aberrant Level of Estrogen Correlates with Defective Thrombopoiesis during Pregnancy in Patients with Immune Thrombocytopenia

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American Society of Hematology

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American Society of Hematology

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