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Journal Articles

Prognostic factors for CNS control in children with acute lymphoblastic leukemia treated without cranial irradiation

Clinical Trials & Observations
Jingyan Tang, Jie Yu, Jiaoyang Cai, Li Zhang, Shaoyan Hu, Ju Gao, Hua Jiang, Yongjun Fang, Changda Liang, Xiuli Ju, Runming Jin, Xiaowen Zhai, Xuedong Wu, Xin Tian, Qun Hu, Ningling Wang, Hui Jiang, Lirong Sun, Alex W. K. Leung, Minghua Yang, Kaili Pan, Cheng Cheng, Yiping Zhu, Hui Zhang, Chunfu Li, Jun J. Yang, Chi-kong Li, Xiaofan Zhu, Shuhong Shen, Ching-Hon Pui
Journal: Blood
Blood (2021) 138 (4): 331–343.
https://doi.org/10.1182/blood.2020010438
Published: 2021
Includes: Supplemental data
Journal Articles

Genetics of osteonecrosis in pediatric acute lymphoblastic leukemia and general populations

Wenjian Yang, Meenakshi Devidas, Yiwei Liu, Colton Smith, Yunfeng Dai, Naomi Winick, Stephen P. Hunger, Mignon L. Loh, Elizabeth A. Raetz, Eric C. Larsen, William L. Carroll, Stuart S. Winter, Kimberly P. Dunsmore, Leonard A. Mattano, Jr, Mary V. Relling, Seth E. Karol
Journal: Blood
Blood (2021) 137 (11): 1550–1552.
https://doi.org/10.1182/blood.2020008471
Published: 2021
Includes: Supplemental data
Journal Articles

Identification of functional cooperative mutations of GNAO1 in human acute lymphoblastic leukemia

Lili Song, Bo Yu, Yi Yang, Jianwei Liang, Yingwen Zhang, Lixia Ding, Tianyi Wang, Xinyu Wan, Xiaomin Yang, Jingyan Tang, Shengyue Wang, Benshang Li, Yanxin Li, Haizhong Feng
Journal: Blood
Blood (2021) 137 (9): 1181–1191.
https://doi.org/10.1182/blood.2020005622
Published: 2021
Includes: Supplemental data
Journal Articles

Enshaei A, O’Connor D, Bartram J, et al. A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia. Blood. 2020;135(17):1438-1446.

Journal: Blood
Blood (2020) 136 (12): 1468.
https://doi.org/10.1182/blood.2020008578
Published: 2020
Journal Articles

A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia

Clinical Trials & Observations
Amir Enshaei, David O’Connor, Jack Bartram, Jeremy Hancock, Christine J. Harrison, Rachael Hough, Sujith Samarasinghe, Monique L. den Boer, Judith M. Boer, Hester A. de Groot-Kruseman, Hanne V. Marquart, Ulrika Noren-Nystrom, Kjeld Schmiegelow, Claire Schwab, Martin A. Horstmann, Gabriele Escherich, Mats Heyman, Rob Pieters, Ajay Vora, John Moppett, Anthony V. Moorman
Journal: Blood
Blood (2020) 135 (17): 1438–1446.
https://doi.org/10.1182/blood.2019003191
Published: 2020
Includes: Supplemental data
Journal Articles

Reduced–dose intensity therapy for pediatric lymphoblastic leukemia: long-term results of the Recife RELLA05 pilot study

Clinical Trials & Observations
Francisco Pedrosa, Elaine Coustan-Smith, Yinmei Zhou, Cheng Cheng, Arli Pedrosa, Mecneide Mendes Lins, Marcia Pedrosa, Norma Lucena-Silva, Alessandra Maria de Luna Ramos, Ester Vinhas, Gaston K. Rivera, Dario Campana, Raul C. Ribeiro
Journal: Blood
Blood (2020) 135 (17): 1458–1466.
https://doi.org/10.1182/blood.2019004215
Published: 2020
Includes: Supplemental data
Journal Articles

Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia

Clinical Trials & Observations
Malwine J. Barz, Jana Hof, Stefanie Groeneveld-Krentz, Jui Wan Loh, Annabell Szymansky, Kathy Astrahantseff, Arend von Stackelberg, Hossein Khiabanian, Adolfo A. Ferrando, Cornelia Eckert, Renate Kirschner-Schwabe
Journal: Blood
Blood (2020) 135 (12): 921–933.
https://doi.org/10.1182/blood.2019002499
Published: 2020
Includes: Supplemental data
Journal Articles

IKZF1 deletions in pediatric acute lymphoblastic leukemia: still a poor prognostic marker?

Clinical Trials & Observations
Martin Stanulla, Hélène Cavé, Anthony V. Moorman
Journal: Blood
Blood (2020) 135 (4): 252–260.
https://doi.org/10.1182/blood.2019000813
Published: 2020
Journal Articles

Beat pediatric ALL MRD: CD28 CAR T and transplant

Clinical Trials & Observations
Marco Ruella, Frederick L. Locke
Journal: Blood
Blood (2019) 134 (26): 2333–2335.
https://doi.org/10.1182/blood.2019003821
Published: 2019
Journal Articles

ROR1 Targeted Immunoliposomal Delivery of OSU-2S Show Selective Cytotoxicity in t(1;19) Translocated B-ALL

Swagata Goswami, MSc, Chi-Ling Chiang, PhD, Kevan Zapolnik, BS, Zhiliang Xie, James L. Lee, PhD, Sivasubramanian Baskar, Christoph Rader, PhD, John C. Byrd, MD, Mitch A. Phelps, PhD, Bhavana Bhatnagar, DO, Natarajan Muthusamy, DVM,PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3798.
https://doi.org/10.1182/blood-2019-128828
Published: 2019
Journal Articles

Whole-Genome CRISPR Screen Reveals the Mechanism of Relapse in Patient-Derived Cells Representing High-Risk Paediatric ALL

Katarzyna Szoltysek, PhD, Helen Blair, Sirintra Nakjang, Ricky Tirtakusuma, Mankaran Singh, Ryan Nelson, Hesta McNeill, Catherine Dodd, Melanie Beckett, Lynsey McKenzie, Edward Law, Josef Vormoor, MD PhD, Deepali Pal, Olaf Heidenreich
Journal: Blood
Blood (2019) 134 (Supplement_1): 3952.
https://doi.org/10.1182/blood-2019-124818
Published: 2019
Journal Articles

Impact of Modifying Conditioning and Immunosuppressive Strategies in Allogeneic Hematopoietic Stem Cell Transplantation in Children with Acute Lymphoblastic Leukemia

Nawar Dakhallah, MD, Mylène Beauchemin, Johanne Richer, Sonia Cellot, MD PhD, Pierre Teira, MD, Michel Duval, MD, Henrique Bittencourt
Journal: Blood
Blood (2019) 134 (Supplement_1): 5714.
https://doi.org/10.1182/blood-2019-122988
Published: 2019
Journal Articles

NUDT15 Variants Confer High Incidence of Secondary Malignancies of ALL in Children

Masanori Yoshida, MD, Kazuhiko Nakabayashi, PhD, Aiko Sato-Otsubo, PhD, Shinichi Tsujimoto, MD PhD, Kaoru Yoshida, MD, Ryota Shirai, MD, Tomoo Osumi, MD, Yuki Yuza, MD PhD, Masatoshi Takagi, MD PhD, Hiroyuki Takahashi, MD PhD, Katsuyoshi Koh, MD, Akitoshi Kinoshita, MD PhD, Moeko Hino, MD, Toshihiko Imamura, MD PhD, Yozo Nakazawa, MD PhD, Okuya Mayuko, MD PhD, Harumi Kakuda, MD PhD, Masashi Sanada, MD, Kimikazu Matsumoto, MD, PhD, Daisuke Tomizawa, MD PhD, Nobutaka Kiyokawa, MD PhD, Akira Ohara, MD PhD, Atsushi Manabe, MD PhD, Kenichiro Hata, MD PhD, Jun J. Yang, PhD, Motohiro Kato, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2751.
https://doi.org/10.1182/blood-2019-125713
Published: 2019
Journal Articles

PI3Kδ Inhibition Enhances Sensitivity of Primary High-Risk Childhood B-Cell Acute Lymphoblastic Leukemia Cells to Glucocorticoid Chemotherapy

Jessica A.O. Zimmerman, MD, Mimi Fang, Arunkumar Modi, MBBS, MPH, Adam Dupuy, PhD, Sarah K. Tasian, MD, Miles A. Pufall, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2572.
https://doi.org/10.1182/blood-2019-129205
Published: 2019
Journal Articles

Lack of Benefit of Extended Vincristine and Dexamethasone Pulses during Maintenance Treatment of Childhood Acute Lymphoblastic Leukemia: A Multicenter Randomized Controlled Study of Chinese Children Cancer Group (CCCG)-ALL-2015

Xiaofan Zhu, Shuhong Shen, MD PhD, Jiaoyang Cai, PhD, Shaoyan Hu, MD PhD, Ju Gao, PhD, Hui Zhang, MD PhD, Yongjun Fang, PhD, Xiuli Ju, Xiaowen Zhai, MD PhD, Xuedong Wu, MD PhD, Changda Liang, MD PhD, Xin Tian, PhD, Qun Hu, MD PhD, Ningling Wang, PhD, Runming Jin, MD, Hui Jiang, PhD, Lirong SUN, PhD, Minghua Yang, MD, Kaili Pan, PhD, Chi Kong Li, MBBS,MD, Jun J. Yang, PhD, Cheng Cheng, PhD, JingYan Tang, MD, Ching-Hon Pui, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2576.
https://doi.org/10.1182/blood-2019-128523
Published: 2019
Journal Articles

Evaluating ROR1 As a Target in Childhood Leukemia

Paraskevi Diamanti, PhD, Bethan Kathleen Bailey, BSc, Obinna Ebere Iheanacho, MD, Amit C. Nathwani, MD PhD, Allison Blair, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2635.
https://doi.org/10.1182/blood-2019-126734
Published: 2019
Journal Articles

Clinical Features of Pediatric Acute Myeloid Leukemia with TP53 and CDKN2A / 2B copy Number Alterations

Yusuke Hara, Tomohiko Taki, MD PhD, Genki Yamato, Kenichi Yoshida, MD PhD, Yusuke Shiozawa, MD PhD, Norio Shiba, MD PhD, Taeko Kaburagi, MD, Yuichi Shiraishi, PhD, Kentaro Ohki, MD PhD, Machiko Kawamura, MD, Manabu Sotomatsu, MD PhD, Hirokazu Arakawa, MD PhD, Hidemasa Matsuo, PhD, Akira Shimada, MD PhD, Tsutomu Toki, PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Etsuro Ito, MD PhD, Keizo Horibe, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Souichi Adachi, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2727.
https://doi.org/10.1182/blood-2019-126263
Published: 2019
Journal Articles

The Outcome of Modified St. Jude Total XV Protocol in Turkish Children with Newly Diagnosed Acute Lymphoblastic Leukemia

Hulya Yilmaz, MD, Selin Aytac, MD, Barış Kuşkonmaz, MD, Duygu Çetinkaya, MD, Sule Unal, MD, Fatma Gumruk, MD, Mualla Çetin, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2590.
https://doi.org/10.1182/blood-2019-130163
Published: 2019
Journal Articles

Whole Genome Profiling of Adult B-Other Acute Lymphoblastic Leukaemia on the UKALL14 Trial

Daniel A. Leongamornlert, PhD, Emilio Barretta, Soo Lee, Thomas Creasey, MBBS, Rachel J. Mitchell, MSc, Amy A. Kirkwood, MSc, Laura Clifton-Hadley, PhDBSc, Pip Patrick, PhDMSc,MA, Peter J Campbell, Bela Wrench, MBBS, MD MRCP, FRCPath, Anthony V. Moorman, Adele K. Fielding, MBBS,PhDFRCP,FRCPath, Elli Papaemmanuil, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2743.
https://doi.org/10.1182/blood-2019-125723
Published: 2019
Journal Articles

Prognostic Value of Minimal Residual Disease Measured By Flow Cytometry in Two Cohorts of Infants with Acute Lymphoblastic Leukemia Treated with MLL-Baby and Interfant Protocols in Large Multicenter Networks

Alexander Popov, MD PhD, Barbara Buldini, MD PhD, Paola De Lorenzo, PhD, Silvia Disaro, Tatiana Verzhbitskaya, MD PhD, Liudmila Movchan, PhD, Emanuela Giarin, Egor Shorikov, MD PhD, Annamaria Di Meglio, Grigory Tsaur, MD PhD, Franco Locatelli, MD PhD, Rosanna Parasole, MD, Natalia Miakova, MD PhD, Elmira Boychenko, MD PhD, Konstantin Kondratchik, MD, Olga Aleinikova, MD PhD, Alexander Karachunskiy, MD PhD, Alexander Roumiantsev, MD PhD, Andrea Biondi, MD PhD, Rob Pieters, MDPhDMSc, Maria Grazia Valsecchi, PhD, Larisa Fechina, MD PhD, Giuseppe Basso, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2747.
https://doi.org/10.1182/blood-2019-130210
Published: 2019