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Journal Articles

FcRn augments induction of tissue factor activity by IgG-containing immune complexes

Douglas B. Cines, Sergei Zaitsev, Lubica Rauova, Ann H. Rux, Victoria Stepanova, Sriram Krishnaswamy, Amrita Sarkar, M. Anna Kowalska, Guohua Zhao, Alan E. Mast, Laurence J. Blumberg, Keith R. McCrae, Mortimer Poncz, Jonathan J. Hubbard, Michal Pyzik, Richard S. Blumberg

Blood (2020) 135 (23): 2085–2093.

https://doi.org/10.1182/blood.2019001133

Published: 2020

Includes: Supplemental data

Journal Articles

Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation

Ian Johnston, Amrita Sarkar, Vincent Hayes, Gavin T. Koma, Gowthami M. Arepally, Junmei Chen, Dominic W. Chung, José A. López, Douglas B. Cines, Lubica Rauova, Mortimer Poncz

Blood (2020) 135 (15): 1270–1280.

https://doi.org/10.1182/blood.2018881607

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Epitope Dependent Augmentation of the Immune Response in Hemophilia Α Mice Immunized with Factor VIII/Antibody Immune Complexes

Glaivy Batsuli, MD, Seema R Patel, PhD, Courtney Cox, MSc, Wallace H. Baldwin, John S. Lollar, MD, Shannon L. Meeks, MD

Blood (2019) 134 (Supplement_1): 2387.

https://doi.org/10.1182/blood-2019-127436

Published: 2019

Journal Articles

Disrupting GRINL1A Association with Cereblon Accelerates IKZF1/3 Degradation and IMiD Killing of Mantle Cell Lymphoma Cells By CDK4/6 Inhibition

Nicole Zhao, Maurizio Di Liberto, PhD, Olivier Elemento, PhD, Selina Chen-Kiang, PhD, Xiangao Huang, PhD

Blood (2019) 134 (Supplement_1): 299.

https://doi.org/10.1182/blood-2019-128927

Published: 2019

Journal Articles

Autoimmune Hemolytic Anemia in Chronic Myeloid Leukemia from Busulfan to the Era of Tyrosine Kinase Inhibitors

Mohamed A Yassin, MBBS, MSc, Tahseen Hamamyh, MD

Blood (2019) 134 (Supplement_1): 5917.

https://doi.org/10.1182/blood-2019-121433

Published: 2019

Journal Articles

Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis

Aleksandra S. Dain, MD, Michelle L. Hermiston, MD PhD, Kristin A. Shimano, MD, Sandhya Kharbanda, MD, Alexis Melton, MD PhD, Jasmeen Dara, MD, James N Huang, MD, Christopher C. Dvorak, MD

Blood (2019) 134 (Supplement_1): 3343.

https://doi.org/10.1182/blood-2019-127397

Published: 2019

Journal Articles

Fluid-Phase Immune Complexes Can Assemble and Activate Platelets in Heparin-Induced Thrombocytopenia

Angela Huynh, BSc, Donald M. Arnold, MD MSc, FRCPC, James W. Smith, Taylor D. Elliott, BSc, Hina Bhakta, John G. Kelton, MD, Ishac Nazy, PhD

Blood (2018) 132 (Supplement 1): 3746.

https://doi.org/10.1182/blood-2018-99-115037

Published: 2018

Journal Articles

Regulatory T Cells Control PF4/Heparin Antibody Production in Mice

Yongwei Zheng, Wen Zhu, Dipica Haribhai, PhD, Calvin B. Williams, PhD, Richard H. Aster, MD, Renren Wen, PhD, Demin Wang, PhD

Blood (2018) 132 (Supplement 1): 2542.

https://doi.org/10.1182/blood-2018-99-113049

Published: 2018

Journal Articles

SKY59: A Long-Lasting Engineered Anti-C5 Antibody for Subcutaneously Injectable Anti-Complement Therapy

Kenta Haraya, PhD, Zenjiro Sampei, PhD, Tatsuhiko Tachibana, PhD, Taku Fukuzawa, PhD, Siok Wan Gan, PhD, Meiri Shida-Kawazoe, PhD, Yuichiro Shimizu, PhD, Masaru Muraoka, PhD, Tomoyuki Igawa, PhD, Takehisa Kitazawa, DVM, Junichi Nezu, PhD

Blood (2018) 132 (Supplement 1): 3611.

https://doi.org/10.1182/blood-2018-99-110145

Published: 2018

Journal Articles

Inhibition of C3 with APL-2 Results in Normalisation of Markers of Intravascular and Extravascular Hemolysis in Patients with Autoimmune Hemolytic Anemia (AIHA)

Federico Grossi, MD, Merrill Kingman Shum, MD, Morie A. Gertz, MD, Eloy Roman, MD, Pascal Deschatelets, PhD, Mohamed Hamdani, MS, Frank Stout, Cedric G Francois, MD PhD

Blood (2018) 132 (Supplement 1): 3623.

https://doi.org/10.1182/blood-2018-99-119468

Published: 2018

Journal Articles

Asparaginase Immune Complexes Detectable after Asparaginase-Induced Hypersensitivities Activate Basophils Via FcγRIII

Sanjay Rathod, PhD, Fred D Finkelman, MD, Christian Fernandez, PhD

Blood (2018) 132 (Supplement 1): 5210.

https://doi.org/10.1182/blood-2018-99-116704

Published: 2018

Journal Articles

Phosphatidylserine-Mediated Procoagulant Activity of Microparticles and Their Originating Cells Contributes to Hypercoagulability in Lupus Nephritis

Li Hou, MD, Tao Li, MD, Yan Zhang, MD, Baorong LI, MD, Yingmiao LIU, MD, Cong Zhang, MD, Yan Kou, MD, Lili Zou, MD, Hui Liang, MD, Yuqing Guan, MD, Xiaojing Chen, MD, Jialan Shi, MD PhD, Rujuan Xie, MD PhD

Blood (2018) 132 (Supplement 1): 2507.

https://doi.org/10.1182/blood-2018-99-115627

Published: 2018

Journal Articles

The Appropriateness of Testing PF4/Heparin Antibody in Patients Suspected of Heparin-Induced Thrombocytopenia

Vishal Jindal, MD MBBS, Aditi Singh, MD, Ahmad Daniyal Siddiqui, MD, Laszlo Leb, MD

Blood (2018) 132 (Supplement 1): 5000.

https://doi.org/10.1182/blood-2018-99-109894

Published: 2018

Journal Articles

Neutrophil Activation and Netosis Are the Key Drivers of Thrombosis in Heparin-Induced Thrombocytopenia

Jose Perdomo, PhD, Halina HL Leung, PhD, Zohra Ahmadi, Yan Feng, PhD, Freda H. Passam, MDPhD, Beng H Chong, MBBS, PhD

Blood (2018) 132 (Supplement 1): 378.

https://doi.org/10.1182/blood-2018-99-116421

Published: 2018

Journal Articles

SYNT001: A Humanized IgG4 Monoclonal Antibody That Disrupts the Interaction of FcRn and IgG for the Treatment of IgG-Mediated Autoimmune Diseases

Laurence Blumberg, MD, John E Humphries, MD, Kenneth C Lasseter, MD, Richard S Blumberg, MD

Blood (2017) 130 (Supplement 1): 3483.

https://doi.org/10.1182/blood.V130.Suppl_1.3483.3483

Published: 2017

Journal Articles

Effective Treatment of Thrombotic Microangiopathy Associated with Lupus Nephritis with Eculizumab: a Series of 8 Cases

Mihee Park, MD BS, Ilene Ceil Weitz, MD

Blood (2017) 130 (Supplement 1): 1043.

https://doi.org/10.1182/blood.V130.Suppl_1.1043.1043

Published: 2017

Journal Articles

The Effect of ABO Immune Complexes on Endothelial Cell Integrity As Measured By Electric Cell-Substrate Impedance Sensing (ECIS) and Confocal Microscopy

Hannah L McRae, Spencer Slavin, B.S., Arshad Rahman, PhD, Neil Blumberg, MD, Majed A Refaai, MD

Blood (2017) 130 (Supplement 1): 2306.

https://doi.org/10.1182/blood.V130.Suppl_1.2306.2306

Published: 2017

Journal Articles

The Role of Transgene Levels in Immune Tolerance Induction after AAV Gene Therapy in Hemophilia B Canine Models

Ben J. Samelson-Jones, MD PhD, Robert Andrew French, BS, Julie M. Crudele, PhD, Timothy C. Nichols, MD, Valder R Arruda, MD PhD

Blood (2017) 130 (Supplement 1): 2057.

https://doi.org/10.1182/blood.V130.Suppl_1.2057.2057

Published: 2017

Journal Articles

Ultrastructural Alterations of Platelets and Monocytes Associated with Autoantibodies in Systemic Lupus Erythematosus

Rustem I. Litvinov, MD PhD, Izabella A. Andrianova, MS, Anastasia A. Ponomareva, PhD, John W. Weisel, PhD

Blood (2017) 130 (Supplement 1): 4804.

https://doi.org/10.1182/blood.V130.Suppl_1.4804.4804

Published: 2017

Journal Articles

ABO Identical and Washed Transfusions Are Candidate Strategies to Reduce Early Mortality in Acute Promyelocytic Leukemia (APL)

Majed A. Refaai, MD, Kelly F Henrichs, BS, MT(ASCP), Joanna M. Heal, MBBS, MRCP, Amy E Schmidt, MD PhD, Jason H. Mendler, MD PhD, Scott A. Kirkley, MD, Christopher Aquina, MD, Debra Masel, BS, MT(ASCP) SBB, Jane Liesveld, MD, Neil Blumberg, MD

Blood (2016) 128 (22): 4011.

https://doi.org/10.1182/blood.V128.22.4011.4011

Published: 2016

NARROW

FcRn augments induction of tissue factor activity by IgG-containing immune complexes

Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation

Epitope Dependent Augmentation of the Immune Response in Hemophilia Α Mice Immunized with Factor VIII/Antibody Immune Complexes

Disrupting GRINL1A Association with Cereblon Accelerates IKZF1/3 Degradation and IMiD Killing of Mantle Cell Lymphoma Cells By CDK4/6 Inhibition

Autoimmune Hemolytic Anemia in Chronic Myeloid Leukemia from Busulfan to the Era of Tyrosine Kinase Inhibitors

Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis

Fluid-Phase Immune Complexes Can Assemble and Activate Platelets in Heparin-Induced Thrombocytopenia

Regulatory T Cells Control PF4/Heparin Antibody Production in Mice

SKY59: A Long-Lasting Engineered Anti-C5 Antibody for Subcutaneously Injectable Anti-Complement Therapy

Inhibition of C3 with APL-2 Results in Normalisation of Markers of Intravascular and Extravascular Hemolysis in Patients with Autoimmune Hemolytic Anemia (AIHA)

Asparaginase Immune Complexes Detectable after Asparaginase-Induced Hypersensitivities Activate Basophils Via FcγRIII

Phosphatidylserine-Mediated Procoagulant Activity of Microparticles and Their Originating Cells Contributes to Hypercoagulability in Lupus Nephritis

The Appropriateness of Testing PF4/Heparin Antibody in Patients Suspected of Heparin-Induced Thrombocytopenia

Neutrophil Activation and Netosis Are the Key Drivers of Thrombosis in Heparin-Induced Thrombocytopenia

SYNT001: A Humanized IgG4 Monoclonal Antibody That Disrupts the Interaction of FcRn and IgG for the Treatment of IgG-Mediated Autoimmune Diseases

Effective Treatment of Thrombotic Microangiopathy Associated with Lupus Nephritis with Eculizumab: a Series of 8 Cases

The Effect of ABO Immune Complexes on Endothelial Cell Integrity As Measured By Electric Cell-Substrate Impedance Sensing (ECIS) and Confocal Microscopy

The Role of Transgene Levels in Immune Tolerance Induction after AAV Gene Therapy in Hemophilia B Canine Models

Ultrastructural Alterations of Platelets and Monocytes Associated with Autoantibodies in Systemic Lupus Erythematosus

ABO Identical and Washed Transfusions Are Candidate Strategies to Reduce Early Mortality in Acute Promyelocytic Leukemia (APL)

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American Society of Hematology

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ASH Publications

American Society of Hematology

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