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Waseem Qasim, MBBS PhD
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Journal Articles

ALLCAR19: Updated Data Using AUTO1, a Novel Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia and Other B-Cell Malignancies

Claire Roddie, PhD MD, Maeve A O'Reilly, MBBCHBAO, Maria A V Marzolini, Leigh Wood, BA, Juliana Dias, Amaia Cadinanos Garai, BSc MSc, Leticia Bosshard, Mahnaz Abbasian, Mark W. Lowdell, BSc, MSc, PhD FRCPath, Graham Wheeler, Joanna Olejnik, Bilyana Popova, MSc, Laura Clifton-Hadley, PhDBSc, Yashma Pathak, Victoria Spanswick, Helen Lowe, John A. Hartley, PhD, Farhatullah Syed, Waseem Qasim, MBBS, PhD, Farzin Farzaneh, PhD, David C. Linch, Martin Pule, MDPhD, Karl S Peggs, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-137768
Published: 2020
Journal Articles

Highly Efficient Multiplexed Base Editing with Minimized Off-Targets for the Development of Universal CAR-T Cells to Treat Pediatric T-ALL

Jason M Gehrke, PhD, Aaron Edwards, MS, Ryan C. Murray, MS, Amy Shaw, MS, Yeh-Chuin Poh, PhD, Sarah Smith, Yi Yu, PhD, Nicole M. Gaudelli, PhD, Waseem Qasim, MBBS, PhD, Giuseppe Ciaramella, PhD, B.Sc.
Journal: Blood
Blood (2019) 134 (Supplement_1): 5127.
https://doi.org/10.1182/blood-2019-130562
Published: 2019
Journal Articles

Universal' Fratricide-Resistant CAR T Cells Against T Cell Leukemia Generated By Coupled & Uncoupled Deamination Mediated Base Editing

Christos Georgiadis, PhD, Jane Rasaiyaah, PhD, Soragia Athina Gkazi, PhD, Roland Preece, Annie Etuk, PhD, Abraham Christi, Waseem Qasim, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3219.
https://doi.org/10.1182/blood-2019-130057
Published: 2019
Journal Articles

A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation

Emma C Morris, Rita Tendeiro-Rego, Rachel Richardson, MSc, Thomas A Fox, BSc, MSc, MRCP, Francesca Sillito, BSc, MRCP, FRCPath, Angelika Holler, Sharyn Thomas, Shao-An Xue, Irma Alicia Martínez-Dávila, Emma Nicholson, Mandana Ahmadi, Judith King, Panagiotis Kottaridis, Ronjon Chakraverty, BMBS, PhD, Kirsty Thomson, Stephen Robinson, MBBS, PhD BSc, Andres E. Virchis, FRCP, FRCPath, Asim Khwaja, Michelle Quaye, Hong Zhan, Waseem Qasim, MBBS, PhD, Nourredine Himoudi, Jacqueline Barry, Natalie Mount, PhD, Terri Gaskell, Michaela Sharpe, Shannon M Inman, Kurt C. Gunter, MD, Hans Stauss
Journal: Blood
Blood (2019) 134 (Supplement_1): 1367.
https://doi.org/10.1182/blood-2019-128044
Published: 2019
Journal Articles

Automated Manufacture of Matched Donor-Derived Allogeneic CD19 CAR T-Cells for Relapsed/Refractory B-ALL Following Allogeneic Stem Cell Transplantation: Toxicity, Efficacy and the Important Role of Lymphodepletion

Claire Roddie, PhD MD, Maeve A O'Reilly, MBBCHBAO, Maria A V Marzolini, Leigh Wood, BA, Juliana Dias Alves Pinto, PhD, Mahnaz Abbasian, Ketki Vispute, Leticia Bosshard, Mark W. Lowdell, BSc, MSc, PhD FRCPath, Graham Wheeler, Alex Day, Bilyana Popova, Kim Champion, Yashma Pathak, Alexia Gali, Nasir Mahmoud, Victoria Spanswick, Helen Lowe, John A. Hartley, PhD, Farzin Farzaneh, PhD, Lauren Nickolay, PhD, Fahetullah Syed, Waseem Qasim, MBBS, PhD, David C. Linch, Martin Pule, Karl S Peggs
Journal: Blood
Blood (2019) 134 (Supplement_1): 776.
https://doi.org/10.1182/blood-2019-129640
Published: 2019
Journal Articles

A Novel Second Generation CD19 CAR for Therapy of High Risk/Relapsed Paediatric CD19 + Acute Lymphoblastic Leukaemia and Other Haematological Malignancies: Preliminary Results from the Carpall Study

Sara Ghorashian, MD PhD FRCPath, Anne Marijn Kramer, MD, Sarah Jayne Albon, BSc, MSc, Catherine Irving, BSc, Lucas Chan, PhD, Fernanda Castro, PhD, Bilyana Popova, Kim Champion, PhD, Gary Wright, Hong Zhan, PhD, Waseem Qasim, MBBS PhD, Robert Wynn, Rachael Hough, MD BMBS, FRCP, FRCPath, Farzin Farzaneh, Martin A Pule, MD PhD, Persis J Amrolia, Professor
Journal: Blood
Blood (2016) 128 (22): 4026.
https://doi.org/10.1182/blood.V128.22.4026.4026
Published: 2016
Journal Articles

Outcome of Children with Primary Immune-Deficiencies (PIDs) Enrolled in a Phase I-II Trial Based on the Infusion of BPX-501 Donor T Cells Genetically Modified with a Novel Suicide Gene (inducible Caspase 9, iC9) after T-Cell Depleted HLA-Haploidentical Allogeneic Stem Cell Transplantation (haplo-HSCT)

Neena Kapoor, MD, Alice Bertaina, MD PhD, Pietro Merli, MD, Swati Naik, MD, Waseem Qasim, MBBS PhD, Mary Slatter, MD, Reem Elfeky, MD, Barbarella Lucarelli, MD, Monika Smogorzewska, PhD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Annemarie Moseley, MD PhD, Franco Locatelli, MD
Journal: Blood
Blood (2016) 128 (22): 72.
https://doi.org/10.1182/blood.V128.22.72.72
Published: 2016
Journal Articles

Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial

Franco Locatelli, Prof, MD PhD, Pietro Merli, MD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Barbarella Lucarelli, MD, Letizia Pomponia Brescia, MD, Mauro Montanari, MD, Daniela Pende, MD, Michela Falco, PhD, Daria Pagliara, MD, Maria Giuseppina Cefalo, MD, Alessandro Moretta, MD, Concetta Quintarelli, PhD, Brigitte Strahm, MD, Waseem Qasim, MBBS PhD, Mary Slatter, Lorenzo Moretta, MD, Annemarie Moseley, MDPhD, Alice Bertaina, MDPhD
Journal: Blood
Blood (2015) 126 (23): 1931.
https://doi.org/10.1182/blood.V126.23.1931.1931
Published: 2015
Journal Articles

Automated Lentiviral Transduction of T Cells with Cars Using the Clinimacs Prodigy

Ulrike Mock*, PhD, Lauren Nickolay*, PhD, Gordon Weng-Kit Cheung, Hong Zhan, PhD, Karl Peggs, MBBChir, MRCP, FRCPath, Ian CD Johnston, PhD, Andrew Kaiser, PhD, Martin Pule, PhD, Adrian Thrasher, MD PhD, Waseem Qasim, MBBS PhD
Journal: Blood
Blood (2015) 126 (23): 2043.
https://doi.org/10.1182/blood.V126.23.2043.2043
Published: 2015
Journal Articles

First Clinical Application of Talen Engineered Universal CAR19 T Cells in B-ALL

Waseem Qasim, MBBS PhD, Persis Jal Amrolia, Sujith Samarasinghe, MD PhD, Sara Ghorashian, MD PhD FRCPath, Hong Zhan, PhD, Sian Stafford, PhD, Katie Butler, PhD, Gul Ahsan, Kimberly Gilmour, Stuart Adams, PhD, Danielle Pinner, Robert Chiesa, Steve Chatters, PhD, Sue Swift, PhD, Nicholas Goulden, MD PhD, Karl Peggs, MBBChir, MRCP, FRCPath, Adrian J Thrasher, MD PhD, Paul Veys, Martin Pule, PhD
Journal: Blood
Blood (2015) 126 (23): 2046.
https://doi.org/10.1182/blood.V126.23.2046.2046
Published: 2015