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Journal Articles

Serially Transplantable, Genetically Modified Patient Derived Xenograft Models of Acute Myeloid Leukemia Represent Primary Patients' Cells and Enable Reliable and Reproducible Preclinical Therapy Trials

Blood (2024) 144 (Supplement 1): 6085.

https://doi.org/10.1182/blood-2024-198652

Published: 2024

Journal Articles

ZBTB7A Loss Promotes Synthesis of Lipids and Ketone Bodies in Myeloid Leukemia

Vanessa C. Arfelli, Werner Schmitz, Martin E. Kirmaier, Enric Redondo Monte, Paul Kerbs, Monica Cusan, Sebastian Theurich, Christian Wichmann, Philipp A. Greif

Blood (2023) 142 (Supplement 1): 1390.

https://doi.org/10.1182/blood-2023-185682

Published: 2023

Journal Articles

D DX41 -Low Expression Mimics Germline DDX41 -Phenotype in Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 820.

https://doi.org/10.1182/blood-2023-187419

Published: 2023

Journal Articles

Synergistic Antileukemic Effect of Mek and Lsd1 Inhibitors Correlates with Decreased Phospho-Serine 315 of TP53

Alessandra Caroleo, Paul Kerbs, Anja Swoboda, Lucas Wange, Stephanie Heinzlmeir, Yun-Chien Chang, Bernhard Küster, Wolfgang Enard, Michael von Bergwelt, Philipp A. Greif, Monica Cusan

Blood (2022) 140 (Supplement 1): 5870–5871.

https://doi.org/10.1182/blood-2022-169202

Published: 2022

Journal Articles

Acute Myeloid Leukemia with Isolated Trisomy 4 Is Characterized By Frequent Mutations of TET2 and a Distinct DNA Methylation Signature

Sayantanee Dutta, Paul Kerbs, Maja Rothenberg-Thurley, Bianka Ksienzyk, Stefan Krebs, Helmut Blum, Karsten Spiekermann, Klaus H. Metzeler, Tobias Herold, Sebastian Vosberg, Philipp A. Greif

Blood (2022) 140 (Supplement 1): 8912–8913.

https://doi.org/10.1182/blood-2022-168939

Published: 2022

Journal Articles

Prevalence, Clinical and Molecular Features, and Prognostic Value of Tetraploidy/Near-Tetraploidy in Patients with Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 3454–3455.

https://doi.org/10.1182/blood-2022-166271

Published: 2022

Journal Articles

CSF3R T618I Collaborates with RUNX1-RUNX1T1 to Expand Human Haematopoietic Stem and Progenitor Cells

Anja Swoboda, Roland Windisch, Paul Kerbs, Enric Redondo Monte, Johannes W. Bagnoli, Linping Chen-Wichmann, Alessandra Caroleo, Monica Cusan, Wolfgang Enard, Tobias Herold, Christian Wichmann, Philipp A. Greif

Blood (2021) 138 (Supplement 1): 2233.

https://doi.org/10.1182/blood-2021-152295

Published: 2021

Journal Articles

An Inducible Leukemia-Associated Transcription Factor Facilitates Large-Scale Ex Vivo Generation of Functional Human Macrophages

Blood (2021) 138 (Supplement 1): 2805.

https://doi.org/10.1182/blood-2021-148336

Published: 2021

Journal Articles

Molecular Subgroups of T Cell Acute Lymphoblastic Leukemia in Adults Treated According to GMALL Protocols

Blood (2020) 136 (Supplement 1): 37–38.

https://doi.org/10.1182/blood-2020-141921

Published: 2020

Journal Articles

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Georg Leubolt, MSc, Paul Kerbs, MSc, Johannes Bagnoli, Wolfgang Hiddemann, MD PhD, Wolfgang Enard, PhD, Sebastian Theurich, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 1453.

https://doi.org/10.1182/blood-2019-128378

Published: 2019

Journal Articles

GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response

Georg Leubolt, MSc, Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Paul Kerbs, MSc, Monica Cusan, MD, Johannes Bagnoli, Wolfgang Enard, PhD, Wolfgang Hiddemann, MD PhD, Christian Wichmann, MD, Gunnar Schotta, PhD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 1459.

https://doi.org/10.1182/blood-2019-128218

Published: 2019

Journal Articles

Gene Fusion Detection By RNA-Seq in Acute Myeloid Leukemia (AML)

Paul Kerbs, MSc, Aarif Mohamed Nazeer Batcha, MSc, Sebastian Vosberg, Dirk Metzler, PhD, Tobias Herold, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 4655.

https://doi.org/10.1182/blood-2019-125869

Published: 2019

Journal Articles

DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome

Sebastian Vosberg, Paul Kerbs, MSc, Vindi Jurinovic, MSc, Klaus H. Metzeler, MD, Susanne Amler, PhD, Cristina Sauerland, Dennis Görlich, PhD, Wolfgang E. Berdel, MD, Jan Braess, MD, Wolfgang Hiddemann, MD PhD, Karsten Spiekermann, MD, Tobias Herold, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 2715.

https://doi.org/10.1182/blood-2019-130047

Published: 2019

Journal Articles

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

Sabrina Opatz, MD, Sebastian Vosberg, Bianka Ksienzyk, Sebastian Tschuri, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, Dr., Stephanie Schneider, PhD, Martin Neumann, Claudia D. Baldus, MD, Christian Thiede, MD, Jan Moritz Middeke, MD, Friedrich Stoelzel, Stefan K. Bohlander, MD, Karsten Spiekermann, MD, Wolfgang Hiddemann, PhD, Klaus H. Metzeler, MD, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 2772.

https://doi.org/10.1182/blood-2018-99-115881

Published: 2018

Journal Articles

GATA2 Zinc Finger Mutations Affect DNA-Binding and Promote Granulopoietic Differentiation

Georg Leubolt, MSc, Belay Tizazu, Sayantanee Dutta, PhD, Monica Cusan, MD, Theresa Sippenauer, Rouzanna Istvanffy, PhD, Robert A.J. Oostendorp, PhD, Wolfgang Hiddemann, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 2779.

https://doi.org/10.1182/blood-2018-99-115976

Published: 2018

Journal Articles

Loss of ZBTB7A Facilitates RUNX1/RUNX1T1-Dependent Clonal Expansion and Sensitizes for Metabolic Inhibition

Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Georg Leubolt, MSc, Luise Hartmann, PhD, Sayantanee Dutta, PhD, Wolfgang Hiddemann, Lingping Chen-Wichmann, PhD, Christian Wichmann, MD, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 1499.

https://doi.org/10.1182/blood-2018-99-114789

Published: 2018

Journal Articles

Homocygous PAX5 Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia

Blood (2017) 130 (Supplement 1): 2713.

https://doi.org/10.1182/blood.V130.Suppl_1.2713.2713

Published: 2017

Journal Articles

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Martin Neumann, Michael P Schroeder, PhD, Lorenz Bastian, Jutta Ortiz Tanchez, Cornelia Schlee, Konstandina Isaakidis, Alva Rani James, Lars R. Fransecky, Sebastian Vosberg, Stefan Krebs, PhD, Helmut Blum, PhD, Stefan Schwartz, MD, Thomas Burmeister, Dieter Hoelzer, MD PhD, Philipp A. Greif, MD, Monika Brüggemann, Nicola Goekbuget, MD, Claudia D. Baldus, MD

Blood (2017) 130 (Supplement 1): 2725.

https://doi.org/10.1182/blood.V130.Suppl_1.2725.2725

Published: 2017

Journal Articles

Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus

Monica Cusan, Naidu M. Vegi, Medhanie A. Mulaw, Shiva Bamezai, Lisa M. Kaiser, Aniruddha J. Deshpande, Philipp A. Greif, Leticia Quintanilla-Fend, Stefanie Göllner, Carsten Müller-Tidow, Keith R. Humphries, Scott A. Armstrong, Wolfgang Hiddemann, Michaela Feuring-Buske, Christian Buske

Blood (2017) 129 (3): 319–323.

https://doi.org/10.1182/blood-2016-04-706978

Published: 2017

Includes: Supplemental data

Journal Articles

Comparison of FLT3-ITD Detection By High-Throughput Amplicon Sequencing to Routine Diagnostics - a Retrospective Analysis of AMLCG Study Patients

Katrin Reiter, MSc, Max Hubmann, MD, Egor Harin, Sebastian Vosberg, Kathrin Bräundl, Bianka Ksienzyk, Stephanie Schneider, PhD, Annika Maria Dufour, PhD, Evelyn Zellmeier, Stefan K. Bohlander, MD, Christina Sauerland, Dipl.-Math, Wolfgang E Berdel, MD, Bernhard J Wörmann, MD, Thomas Büchner, MD, Jan Braess, MD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A. Greif, MD

Blood (2016) 128 (22): 1682.

https://doi.org/10.1182/blood.V128.22.1682.1682

Published: 2016

NARROW

Serially Transplantable, Genetically Modified Patient Derived Xenograft Models of Acute Myeloid Leukemia Represent Primary Patients' Cells and Enable Reliable and Reproducible Preclinical Therapy Trials

ZBTB7A Loss Promotes Synthesis of Lipids and Ketone Bodies in Myeloid Leukemia

D DX41 -Low Expression Mimics Germline DDX41 -Phenotype in Acute Myeloid Leukemia

Synergistic Antileukemic Effect of Mek and Lsd1 Inhibitors Correlates with Decreased Phospho-Serine 315 of TP53

Acute Myeloid Leukemia with Isolated Trisomy 4 Is Characterized By Frequent Mutations of TET2 and a Distinct DNA Methylation Signature

Prevalence, Clinical and Molecular Features, and Prognostic Value of Tetraploidy/Near-Tetraploidy in Patients with Acute Myeloid Leukemia

CSF3R T618I Collaborates with RUNX1-RUNX1T1 to Expand Human Haematopoietic Stem and Progenitor Cells

An Inducible Leukemia-Associated Transcription Factor Facilitates Large-Scale Ex Vivo Generation of Functional Human Macrophages

Molecular Subgroups of T Cell Acute Lymphoblastic Leukemia in Adults Treated According to GMALL Protocols

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response

Gene Fusion Detection By RNA-Seq in Acute Myeloid Leukemia (AML)

DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

GATA2 Zinc Finger Mutations Affect DNA-Binding and Promote Granulopoietic Differentiation

Loss of ZBTB7A Facilitates RUNX1/RUNX1T1-Dependent Clonal Expansion and Sensitizes for Metabolic Inhibition

Homocygous PAX5 Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus

Comparison of FLT3-ITD Detection By High-Throughput Amplicon Sequencing to Routine Diagnostics - a Retrospective Analysis of AMLCG Study Patients

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American Society of Hematology

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American Society of Hematology

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