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Shiva Bamezai
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Journal Articles

An Aberrantly Overexpressed Short Isoform of TET1 Lacking a DNA Binding Domain Drives Aberrant 5-Hydroxymethylation Marks, Oncogenic Pathways, and Growth in Acute Myeloid Leukemia

Shiva Bamezai, Jing He, Pradeep Rajput, Deniz Sahin, Alex Jose Pulikkottil, Fabian Mohr, Mahalakshmi Naidu Vegi, Rana Pratap Singh, Deepshi Thakral, Ritu Gupta, Christian Buske, Vijay Pal Singh Rawat
Journal: Blood
Blood (2024) 144 (Supplement 1): 4114.
https://doi.org/10.1182/blood-2024-205890
Published: 2024
Journal Articles

A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML

Shiva Bamezai, Alex Jose Pulikkottil, Tribhuwan Yadav, Naidu M. Vegi, Julia Mueller, Jasmin Mark, Tamoghna Mandal, Kristin Feder, Susann Ihme, Chenlin Song, Reinhild Rosler, Sebastian Wiese, Jessica I. Hoell, Andreas Kloetgen, Aly Karsan, Ankita Kumari, Luke Wojenski, Amit U. Sinha, Irene Gonzalez-Menendez, Leticia Quintanilla-Martinez, Elisa Donato, Andreas Trumpp, Elisabeth Kruse, Stephan Hamperl, Lee Zou, Vijay P. S. Rawat, Christian Buske
Journal: Blood
Blood (2023) 142 (1): 90–105.
https://doi.org/10.1182/blood.2022018651
Published: 2023
Includes: Supplemental data
Journal Articles

The Non-Canonical, R-Loop Regulatory Function of PIWIL4 Maintains Genomic Integrity and Leukemic Potential of AML Cells

Shiva Bamezai, PhD, Naidu Vegi, PhD, Alex Pulikkottil Jose, Julia Müller, BSc., Ingrid Grummt, Chenlin Song, PhD, Konstanze Döhner, MD, Hartmut Döhner, MD, Michaela Feuring-Buske, MD, Vijay Pal Singh Rawat, PhD, Christian Buske, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 879.
https://doi.org/10.1182/blood-2018-99-113281
Published: 2018
Journal Articles

Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus

Brief Report
Monica Cusan, Naidu M. Vegi, Medhanie A. Mulaw, Shiva Bamezai, Lisa M. Kaiser, Aniruddha J. Deshpande, Philipp A. Greif, Leticia Quintanilla-Fend, Stefanie Göllner, Carsten Müller-Tidow, Keith R. Humphries, Scott A. Armstrong, Wolfgang Hiddemann, Michaela Feuring-Buske, Christian Buske
Journal: Blood
Blood (2017) 129 (3): 319–323.
https://doi.org/10.1182/blood-2016-04-706978
Published: 2017
Includes: Supplemental data
Journal Articles

The PARP Inhibitor Olaparib Antagonizes Leukemic Growth Induced By TET1 Overexpression in AML1-ETO Positive Acute Myeloid Leukemia

Shiva Bamezai, PhD, Jing He, Dr., Deniz Sahin, M.Sc, Fabian Mohr, PhD, Fabio Ciccarone, PhD, Naidu M Vegi, PhD, Alex Pulikkottil Jose, M.Sc, Medhanie A. Mulaw, Jun.-Prof. Dr., Paola Caiafa, MD, Konstanze Döhner, Hartmut Döhner, MD, Michaela Feuring-Buske, PD Dr., Christian Buske, Vijay P.S. Rawat, PhD
Journal: Blood
Blood (2016) 128 (22): 4063.
https://doi.org/10.1182/blood.V128.22.4063.4063
Published: 2016
Journal Articles

The Methylcytosine Dioxygenase TET3 Is Aberrantly Expressed in Acute Myeloid Leukemia and Promotes AML Growth

Alex Pulikkottil Jose, M.Sc, Fabian Mohr, PhD, Shiva Bamezai, PhD, Holzmann Karlheinz, Dr., Ursula Kohlhofer, Dr. MD vet., Leticia Quintanilla-Martinez Fend, Prof. Dr., Tadafumi Iino, Dr., Koichi Akashi, MD PhD, Konstanze Döhner, Hartmut Döhner, MD, Michaela Feuring-Buske, PD Dr., Christian Buske, Vijay P.S. Rawat, PhD
Journal: Blood
Blood (2016) 128 (22): 771.
https://doi.org/10.1182/blood.V128.22.771.771
Published: 2016
Journal Articles

TET1 Promotes Leukemic Growth in T-ALL Via Maintenance of 5-Hydroxymethylation Marks and Can be Antagonized By the PARP Inhibitor Olaparib

Deniz Sahin, M.Sc, Shiva Bamezai, PhD, Fabio Ciccarone, PhD, Elena Fischbein, MSc, Fabian Mohr, PhD, Medhanie A. Mulaw, Jun.-Prof. Dr., Alex Pulikkottil Jose, M.Sc, Paola Caiafa, MD, Lüder-Hinrich Meyer, MD, Klaus-Michael Debatin, Prof. Dr., Geertruy te Kronnie, PhD, Konstanze Döhner, Hartmut Döhner, Prof. Dr., Michaela Feuring-Buske, PD Dr., Christian Buske, Vijay P.S. Rawat, PhD
Journal: Blood
Blood (2016) 128 (22): 737.
https://doi.org/10.1182/blood.V128.22.737.737
Published: 2016
Journal Articles

Knockdown Of The Piwi - Like Protein 4 (PIWIL4) Delays Leukemic Growth and Is Associated With Gross Changes In The Global Histone Methylation Marks In Human MLL - Rearranged AML

Shiva Bamezai, Medhanie M Mulaw, PhD, Fengbiao Zhou, Christian Rohde, PhD, Carsten Muller-Tidow, MD, Konstanze Dohner, M.D., Hartmut Dohner, MD, Michaela Feuring Buske, MD, Christian Buske, MD, Vijay P.S Rawat, PhD
Journal: Blood
Blood (2013) 122 (21): 597.
https://doi.org/10.1182/blood.V122.21.597.597
Published: 2013