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Laurène Fenwarth
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Journal Articles

Treatments and Outcomes of Adult Patients with AML in the Real-Life - First Report of the French Observational ALFA-PPP Study

Hervé Dombret, Alexandra Coelho, Laurène Fenwarth, Jean-Baptiste Micol, Lionel Ades, Thomas Cluzeau, Emmanuel Raffoux, Sylvain Chantepie, Pierre Arnautou, Mathieu Leclerc, Delphine Lebon, Thorsten Braun, Ollivier Legrand, Claire Bories, Céline Berthon, Juliette Lambert, Ahmad Aljijakli, Emilie Lemasle, Pascal Turlure, Benjamin Carpentier, Jamile Frayfer, Stephanie Haiat, Ambroise Marcais, Isabelle Plantier, Kevin-James Wattebled, Madalina Uzunov, Iona Vaida, Mael Heiblig, Lauris Gastaud, Laure Farnault, Dominique Penther, Nicole Raus, Renaud Buffet, Karine Celli-Lebras, Claude Preudhomme, Nicolas Duployez, Raphael Itzykson, Stephane De Botton
Journal: Blood
Blood (2024) 144 (Supplement 1): 2424.
https://doi.org/10.1182/blood-2024-207226
Published: 2024
Journal Articles

Long Term Follow-up Data after Consolidation Therapy with Ponatinib in Combination with Cytarabine in Patients with FLT3 Mutated Acute Myeloid Leukemia in First Complete Remission

Thibaut Leguay, Laurène Fenwarth, Thomas Cluzeau, Anne Vekoff, Etienne Lengline, Juliette Lambert, Denis Caillot, Mathilde Hunault, Jean-Valère Malfuson, Sylvain Chantepie, Emmanuelle Tavernier, Berengere Gruson, José Fernandes, Pierre Peterlin, Melody Fort, Laure Morisset, Herve Dombret, Claude Preudhomme, Arnaud Pigneux, Philippe Rousselot
Journal: Blood
Blood (2024) 144 (Supplement 1): 2905.
https://doi.org/10.1182/blood-2024-209998
Published: 2024
Journal Articles

Involvement of the JAK-STAT Pathway in the Molecular Landscape of Fusion-Free Myeloid Neoplasms with Eosinophilia

Matthieu Groh, Laurène Fenwarth, Augustin Boudry, Elise Fournier, Alice Marceau-Renaut, Julie Abraham, Marly Barry, Philippe Blanche, Quentin Bodard, Thorsten Braun, Safia Chebrek, Rafael Daltro De Oliveira, Matthieu Decamp, Cécile Audrey Durel, Edouard Forcade, Mathieu Gerfaud-Valentin, Camille Golfier, Clement Gourguechon, Nathalie Grardel, Olivier Kosmider, Mathilde Labro, Sarah Melboucy Belkhir, Fatiha Merabet, Adrien Michon, Nihal Martis, Cécile Morice, Stephane Moreau, Antoine Néel, Franck E. Nicolini, Laurent Pascal, Florence Pasquier, Andrea Pieragostini, Catherine Roche-Lestienne, Philippe Rousselot, Anne Thiebaut, Jean-Francois Viallard, Mathieu Wemeau, Claude Preudhomme, Jean-Emmanuel Kahn, Guillaume Lefèvre, Nicolas Duployez
Journal: Blood
Blood (2023) 142 (Supplement 1): 78.
https://doi.org/10.1182/blood-2023-181250
Published: 2023
Journal Articles

The Occurrence of Infection and TP53 Mutation Are Risk Factors for Cardiovascular Toxicity of Acute Myeloid Leukemia Induction Therapy

Hélène Kemp, Laurène Fenwarth, Delphine Lebon, Nicolas Duployez, Etienne Paubelle, Magalie Joris, Amandine Charbonnier, Lydia Montes, Claude Preudhomme, Christophe Tribouilloy, Jean Pierre Marolleau, Pierre Morel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3815.
https://doi.org/10.1182/blood-2023-190177
Published: 2023
Journal Articles

Genomic Characterization of Acute Myeloid Leukemia with Aberrations of Chromosome 7: A Multinational Cohort of 523 Patients

Adriane Halik, Marlon Tilgner, Patricia Silva, Natalia Estrada-Barreras, Robert Altwasser, Ekaterina Jahn, Michael Heuser, Hsin-An Hou, Marta Pratcorona, Robert Kerrin Hills, Klaus H Metzeler, Laurène Fenwarth, Anna Dolnik, Christine Terré, Klara Kopp, Martin Szyska, Jan Krönke, Loïc Vasseur, Bob Lowenberg, Jordi Esteve, Peter J. M. Valk, Matthieu Duchmann, Wen-Chien Chou, David C. Linch, Hartmut Döhner, Rosemary E. Gale, Konstanze Döhner, Lars Bullinger, Kenichi Yoshida, Frederik Damm
Journal: Blood
Blood (2023) 142 (Supplement 1): 63.
https://doi.org/10.1182/blood-2023-185627
Published: 2023
Journal Articles

Clonal Dynamics of FLT3 -ITD Positive Acute Myeloid Leukemia Patients with Relapsed/Refractory Disease Following Intensive Chemotherapy +/- Midostaurin

Romane Joudinaud, Augustin Boudry, Laurène Fenwarth, Sandrine Geffroy, Mikaël Salson, Herve Dombret, Céline Berthon, Arnaud Pigneux, Delphine Lebon, Lamya Haddaoui, Raphael Itzykson, Christian Recher, Audrey Bidet, Eric Delabesse, Mathilde Hunault, Claude Preudhomme, Nicolas Duployez, Pierre-Yves Dumas
Journal: Blood
Blood (2023) 142 (Supplement 1): 976.
https://doi.org/10.1182/blood-2023-182018
Published: 2023
Journal Articles

Prognostic Impact of Monoallelic Versus Biallelic TP53 Alterations in Intensively-Treated Adults AML Patients: A Retrospective Study from the ALFA Group

Laurène Fenwarth, Loïc Vasseur, Nicolas Duployez, Claude Gardin, Christine Terré, Juliette Lambert, Stéphane de Botton, Karine Celli-Lebras, Pascal Turlure, Thomas Cluzeau, Thorsten Braun, Xavier Thomas, Christian Recher, Sylvain Chantepie, Cécile Pautas, Hervé Dombret, Claude Preudhomme, Raphael Itzykson
Journal: Blood
Blood (2022) 140 (Supplement 1): 737–738.
https://doi.org/10.1182/blood-2022-163044
Published: 2022
Journal Articles

LSC17 Score Is Complementary with Minimal Residual Disease to Stratify NPM1 -Mutated Acute Myeloid Leukemia: An ALFA Study

Loïc Vasseur, Laurène Fenwarth, Xavier Thomas, Jérôme Lambert, Stéphane de Botton, Martin Figeac, Céline Villenet, Pierre-Yves Dumas, Christian Recher, Céline Berthon, Emilie Lemasle, Delphine Lebon, Juliette Lambert, Christine Terré, Karine Celli-Lebras, Hervé Dombret, Claude Preudhomme, Meyling Cheok, Raphael Itzykson, Nicolas Duployez
Journal: Blood
Blood (2022) 140 (Supplement 1): 6303–6305.
https://doi.org/10.1182/blood-2022-163348
Published: 2022
Journal Articles

Persistence of Mutations in Complete Remission Including DNMT3A , TET2 and ASXL1 Mutations Is Associated with Worse Prognosis in Patients with Acute Myeloid Leukemia Treated in ALFA 0702 Study

Pierre Hirsch, Jérôme Lambert, Maxime Bucci, Caroline Deswarte, Juliette Lambert, Laurène Fenwarth, Herve Dombret, Nicolas Duployez, Claude Preudhomme, Raphael Itzykson, Francois Delhommeau
Journal: Blood
Blood (2022) 140 (Supplement 1): 549–550.
https://doi.org/10.1182/blood-2022-166713
Published: 2022
Journal Articles

Long-Term Evolution of Somatic Mutations in Patients with Del(5q) MDS Early Treated with Lenalidomide in the Sintra-Rev Clinical Trial: Safe and Effecitive Approach?

Sofía M Toribio Castelló, Felix Lopez-Cadenas, Claude Preudhomme, Angela Villaverde Ramiro, Laurène Fenwarth, Eva Lumbreras, Teresa González, Mónica Del Rey, Blanca Xicoy, Aline Renneville, Joaquín Sánchez-Garcia, Rosa Coll, Bohrane Slama, José Ángel Hernández-Rivas, Sylvain Thepot, Teresa Bernal, Agnès Guerci-Bresler, Katharina Götze, Jesús María Hernández-Rivas, Pierre Fenaux, Consuelo Del Cañizo, Maria Diez-Campelo
Journal: Blood
Blood (2022) 140 (Supplement 1): 9740–9743.
https://doi.org/10.1182/blood-2022-168599
Published: 2022
Journal Articles

Comparison of Risk Stratification Tools (ELN-2022, ELN-2017, Lindsley et al. , Papaemmanuil et al. and ALFA classifier) in Predicting Outcomes of Patients with Acute Myeloid Leukemia

Alexandre Iat, Michael Loschi, Sami Benachour, Anne Calleja, Edmond Chiche, Isabelle Sudaka, Danièle Aquaronne, Corinne Ferrero, Patricia Brugel, Lea Ryffel, Laurène Fenwarth, Alice Marceau, Elise Fournier, Berengere Dadone, Thomas Cluzeau
Journal: Blood
Blood (2022) 140 (Supplement 1): 9105–9106.
https://doi.org/10.1182/blood-2022-164583
Published: 2022
Journal Articles

Prognostic impact of DDX41 germline mutations in intensively treated acute myeloid leukemia patients: an ALFA-FILO study

Clinical Trials & Observations
Nicolas Duployez, Laëtitia Largeaud, Matthieu Duchmann, Rathana Kim, Julie Rieunier, Juliette Lambert, Audrey Bidet, Lise Larcher, Jean Lemoine, François Delhommeau, Pierre Hirsch, Laurène Fenwarth, Olivier Kosmider, Justine Decroocq, Anne Bouvier, Yannick Le Bris, Marlène Ochmann, Alberto Santagostino, Lionel Adès, Pierre Fenaux, Xavier Thomas, Jean-Baptiste Micol, Claude Gardin, Raphael Itzykson, Jean Soulier, Emmanuelle Clappier, Christian Recher, Claude Preudhomme, Arnaud Pigneux, Hervé Dombret, Eric Delabesse, Marie Sébert
Journal: Blood
Blood (2022) 140 (7): 756–768.
https://doi.org/10.1182/blood.2021015328
Published: 2022
Includes: Supplemental data
Journal Articles

Germline PAX5 mutation predisposes to familial B-cell precursor acute lymphoblastic leukemia

Nicolas Duployez, Laura A. Jamrog, Vincent Fregona, Camille Hamelle, Laurène Fenwarth, Sophie Lejeune, Nathalie Helevaut, Sandrine Geffroy, Aurélie Caillault, Alice Marceau-Renaut, Stéphanie Poulain, Catherine Roche-Lestienne, Laetitia Largeaud, Naïs Prade, Stéphanie Dufrechou, Sylvie Hébrard, Céline Berthon, Brigitte Nelken, José Fernandes, Céline Villenet, Martin Figeac, Bastien Gerby, Eric Delabesse, Claude Preudhomme, Cyril Broccardo
Journal: Blood
Blood (2021) 137 (10): 1424–1428.
https://doi.org/10.1182/blood.2020005756
Published: 2021
Includes: Supplemental data
Journal Articles

A personalized approach to guide allogeneic stem cell transplantation in younger adults with acute myeloid leukemia

Clinical Trials & Observations
Laurène Fenwarth, Xavier Thomas, Stéphane de Botton, Nicolas Duployez, Jean-Henri Bourhis, Auriane Lesieur, Gael Fortin, Paul-Arthur Meslin, Ibrahim Yakoub-Agha, Pierre Sujobert, Pierre-Yves Dumas, Christian Récher, Delphine Lebon, Céline Berthon, Mauricette Michallet, Arnaud Pigneux, Stéphanie Nguyen, Sylvain Chantepie, Norbert Vey, Emmanuel Raffoux, Karine Celli-Lebras, Claude Gardin, Juliette Lambert, Jean-Valère Malfuson, Denis Caillot, Sébastien Maury, Benoît Ducourneau, Pascal Turlure, Emilie Lemasle, Cécile Pautas, Sylvie Chevret, Christine Terré, Nicolas Boissel, Gérard Socié, Hervé Dombret, Claude Preudhomme, Raphael Itzykson
Journal: Blood
Blood (2021) 137 (4): 524–532.
https://doi.org/10.1182/blood.2020005524
Published: 2021
Includes: Supplemental data
Journal Articles

Inherited transmission of the CSF3R T618I mutational hotspot in familial chronic neutrophilic leukemia

Nicolas Duployez, Christophe Willekens, Isabelle Plo, Alice Marceau-Renaut, Stéphane de Botton, Laurène Fenwarth, Thomas Boyer, Guillemette Huet, Olivier Nibourel, Christian Rose, Brigitte Nelken, Bruno Quesnel, Claude Preudhomme
Journal: Blood
Blood (2019) 134 (26): 2414–2416.
https://doi.org/10.1182/blood.2019003206
Published: 2019
Includes: Supplemental data
Journal Articles

Integrating ELN Criteria and a 'Knowledge Bank' Approach to Guide Allogeneic Stem Cell Transplantation (SCT) Indication in Younger Adults with Acute Myeloid Leukemia (AML): An Acute Leukemia French Association Study

Laurène Fenwarth, MD MSc, Raphael Itzykson, MD PhD, Stephane De Botton, MD PhD, Nicolas Duployez, PharmD, PhD, Pierre Sujobert, MD PhD, Céline Berthon, MD PhD, Arnaud Pigneux, Sylvain Chantepie, MD, Christian Recher, MD PhD, Emmanuel Raffoux, MD, Juliette Lambert, MD, Karine Celli-Lebras, CRA, Denis Caillot, MD, Benoit Ducourneau, PharmD, Pascal Turlure, MD, Emilie Lemasle, MD, Cecile Pautas, MD, Norbert Vey, MD PhD, Sylvie Chevret, MD PhD, Christine Terré, PharmD, PhD, Xavier Thomas, MD PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1423.
https://doi.org/10.1182/blood-2019-122468
Published: 2019
Journal Articles

Clofarabine-Based Consolidation Improves Relapse-Free Survival of Patients with Acute Myeloid Leukemia with Complex or Micro-Complex Karyotype: Results from the Randomized ALFA-0702 Study

Laurène Fenwarth, MSc, MD, Nicolas Duployez, PharmD, PhD, Xavier Thomas, MD, Nicolas Boissel, MD PhD, Sandrine Geffroy, PhD, Alice Marceau-Renaut, PharmD, Denis Caillot, MD, Emmanuel Raffoux, MD, Emilie Lemasle, MD, Jean-Pierre Marolleau, MD PhD, Céline Berthon, MD PhD, Meyling H. Cheok, MSPharm, PhD, Pauline Peyrouze, Arnaud Pigneux, MD PhD, Norbert Vey, Karine Celli-Lebras, CRA, Christine Terré, PharmD, PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 465.
https://doi.org/10.1182/blood.V130.Suppl_1.465.465
Published: 2017