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Joan Bladé Creixenti
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Journal Articles

Sustained Recovery of Uninvolved Heavy/Light Chain Pair Immunoparesis during Maintenance Discriminates Patients with Sustained Negative Minimal Residual Disease

Sunil Lakhwani, Laura Rosiñol, Noemi Puig, Miguel Angel Pico Picos, Laura Medina-González, Joaquin Martinez Lopez, Bruno Paiva, Maria Teresa Cedena Romero, Albert Oriol, Rafael Ríos, María Jesús Blanchard, Isidro Jarque, Joan Bargay, Jose Maria Moraleda, Estrella Carrillo-Cruz, Anna Maria Sureda Balari, Isabel Krsnik, Esther Gonzalez Garcia, Luis Felipe Casado Montero, Josep Maria Marti Tutusaus, Cristina Encinas Rodriguez, Felipe De Arriba, Luis Palomera, Antonia Sampol Mayol, Yolanda González-Montes, Cristina Motlló, Javier De la Cruz, Rafael Alonso Fernández, Maria-Victoria Mateos, Joan Blade Creixenti, Juan Jose Lahuerta Palacios, Jesus San Miguel, Miguel Teodoro Hernández Garcia
Journal: Blood
Blood (2023) 142 (Supplement 1): 1958.
https://doi.org/10.1182/blood-2023-179452
Published: 2023
Journal Articles

Biological and Clinical Significance of Undetectable Circulating Tumor Cells (CTCs) in Patients (Pts) with Multiple Myeloma (MM)

Juan-José Garcés, Rosalinda Termini, Esperanza Martín-Sánchez, Marta Lasa, Jose J Perez, Norma C. Gutierrez, Manuela Fernández, Maria Jose Calasanz, Laura Rosiñol, Miguel Teodoro Hernández Garcia, Albert Oriol, Anna Maria Sureda Balari, Albert Perez Montaña, Enrique M Ocio, Maria Casanova Espinosa, Felipe Prosper, Joaquin Martinez-Lopez, Jorge Labrador, Esther Gonzalez Garcia, Rafael Ríos, Fernando Escalante, Joan Bargay, Elena Cabezudo, Valentín Cabañas, Niels Weinhold, Aldo Roccaro, Herve Avet-Loiseau, Alberto Orfao, Joan Blade Creixenti, Maria Victoria Mateos, Juan Jose Lahuerta Palacios, Jesus San-Miguel, María T Cedena, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 646.
https://doi.org/10.1182/blood-2023-186411
Published: 2023
Journal Articles

Recovery of Uninvolved Heavy/Light Chain Pair Immunoparesis during Maintenance Is an Independent Prognostic Factor for Multiple Myeloma and Could Complement Prognosis Value of Minimal Residual Disease

Sunil Lakhwani, Laura Rosinol Dachs, Noemi Puig, Miguel Angel Pico Picos, Laura Medina-González, Joaquín Martínez-López, Bruno Paiva, Albert Oriol, Rafael Rios, María Jesús Blanchard, Isidro Jarque, Joan Bargay, Jose Maria Moraleda, Estrella Carrillo-Cruz, Anna Sureda, Isabel Krsnik, Esther González Garcia, Luis Felipe Casado Montero, Josep M Marti, Cristina Encinas, Felipe De Arriba, Luis Palomera, Antonia Sampol, Yolanda Gonzalez-Montes, Cristina Motllo, Javier De La Cruz, Rafael Alonso Fernández, María-Victoria Mateos, Joan Bladé Creixenti, Juan-José Lahuerta, Jesús San-Miguel, Miguel-Teodoro Hernández
Journal: Blood
Blood (2022) 140 (Supplement 1): 2101–2103.
https://doi.org/10.1182/blood-2022-167247
Published: 2022
Journal Articles

Immunoparesis Recovery in Transplant-Ineligible Newly Diagnosis Multiple Myeloma Patients: An Independent Prognosis Factor That Could Complement Prognostic Value of Minimal Residual Disease

Sunil Lakhwani, María Victoria Mateos, Joaquín Martínez-López, Bruno Paiva, Laura Rosinol Dachs, Rafael Martínez, Albert Oriol, Joan Bargay, Yolanda Gonzalez-Montes, Mercedes Gironella, Cristina Encinas, Jesus Martin, Isidro Jarque, Miquel Granell, Eugenia Abella, Aránzazu García Mateo, José Ángel Hernández-Rivas, Elena Ramila, Isabel Krsnik, Luis Felipe Casado Montero, Felipe De Arriba, Luis Palomera, Antonia Sampol, Jose Maria Moraleda, Maria Casanova, Pilar Delgado, Ana Lafuente, Elena Amutio, Aurelio Lopez Martínez, Albert Altés, M. Ángeles Ruíz, Lucia Lopez-Anglada, Joan Bladé Creixenti, Juan-José Lahuerta, Jesús San-Miguel, Miguel-Teodoro Hernández
Journal: Blood
Blood (2022) 140 (Supplement 1): 2344–2346.
https://doi.org/10.1182/blood-2022-166826
Published: 2022
Journal Articles

Bicistronic CAR T Cell Against CD229 and BCMA Effectively Controls Multiple Myeloma

Luis Gerardo Rodríguez-Lobato, Oriol Cardus, Joan Mañe-Pujol, Anthony M Battram, Lorena Pérez-Amill, Hugo Calderón, Beatriz Martin-Antonio, Aina Oliver-Caldes, Agnès Garcias-López, Ester Lozano, David F. Moreno, Valentín Ortiz-Maldonado, Maria Queralt Salas, Anna de Daniel i Bisbe, Natalia Tovar, Raquel Jiménez-Segura, M. Teresa Cibeira, Laura Rosinol Dachs, Joan Bladé Creixenti, Manel Juan, Álvaro Urbano-Ispizua, Pablo Engel, Carlos Fernandez de Larrea
Journal: Blood
Blood (2022) 140 (Supplement 1): 10281–10282.
https://doi.org/10.1182/blood-2022-166764
Published: 2022
Journal Articles

Daratumumab Plus Bortezomib, Melphalan, and Prednisone (D-VMP) Versus Bortezomib, Melphalan, and Prednisone (VMP) Alone in Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma (NDMM): Updated Analysis of the Phase 3 Alcyone Study

Maria-Victoria Mateos, Jesús San-Miguel, Michele Cavo, Joan Bladé Creixenti, Kenshi Suzuki, Andrzej Jakubowiak, Stefan Knop, Chantal Doyen, Paulo Lucio, Zsolt Nagy, Ludek Pour, Sebastian Grosicki, Andre H Crepaldi, Anna Marina Liberati, Philip Campbell, Tatiana Shelekhova, Sung-Soo Yoon, Genadi Iosava, Tomoaki Fujisaki, Mamta Garg, Huiling Pei, Maria Krevvata, Robin Carson, Fredrik Borgsten, Meletios A. Dimopoulos
Journal: Blood
Blood (2022) 140 (Supplement 1): 10157–10159.
https://doi.org/10.1182/blood-2022-163347
Published: 2022
Journal Articles

Evolving Pattern Improves the IMWG 2/20/20 Classification for Patients with Smoldering Multiple Myeloma

Luis Gerardo Rodríguez-Lobato, Anna de Daniel i Bisbe, Natalia Tovar, Raquel Jiménez-Segura, M. Teresa Cibeira, David F. Moreno, Aina Oliver-Caldes, Alexandra Martínez-Roca, Ester Lozano, Joan Bladé Creixenti, Laura Rosinol Dachs, Carlos Fernandez de Larrea
Journal: Blood
Blood (2022) 140 (Supplement 1): 4341–4342.
https://doi.org/10.1182/blood-2022-165371
Published: 2022
Journal Articles

Clinical Impact of Next Generation Flow in Bone Marrow Vs Qip-Mass Spectrometry in Peripheral Blood to Assess Minimal Residual Disease in Newly Diagnosed Multiple Myeloma Patients Receiving Maintenance As Part of the GEM2014MAIN Trial

Noemi Puig, Cristina Agulló, Teresa Contreras Sanfeliciano, Bruno Paiva, María Teresa Cedena, Laura Rosinol Dachs, Ramón García-Sanz, Joaquín Martínez-López, Albert Oriol, María Jesús Blanchard, Rafael Rios, Jesus Martin, Anna Sureda, Miguel Hernández, Javier de la Rubia, Jose Maria Moraleda, Felipe De Arriba, Luis Palomera, Belén Iñigo, Joan Bargay, Joan Bladé Creixenti, Jesús San-Miguel, Juan Jose Lahuerta, María-Victoria Mateos
Journal: Blood
Blood (2022) 140 (Supplement 1): 2098–2100.
https://doi.org/10.1182/blood-2022-165441
Published: 2022
Journal Articles

Ultra-Sensitive Assessment of Measurable Residual Disease (MRD) in Peripheral Blood (PB) of Multiple Myeloma (MM) Patients Using Bloodflow

Laura Notarfranchi, Anastasiia Zherniakova, Marta Lasa, Noemi Puig, María Teresa Cedena, Joaquin Martinez-Lopez, María José Calasanz, Diego Alignani, Leire Burgos, Irene Manrique, Yi-Ju Huang, Jochen Fracowiak, Clara Gomez, Felipe De Arriba, Paula Rodríguez-Otero, Luis Palomera, Anna Sureda, Maria Esther Clavero Sanchez, Miguel Angel Alvarez, Angela Ibanez Garcia, Miguel-Teodoro Hernández, Albert Perez, Ana Pilar Gonzalez, Enrique M. Ocio, Juan Flores-Montero, Alberto Orfao, Juan Jose Lahuerta, María-Victoria Mateos, Laura Rosiñol, Joan Bladé Creixenti, Jesús San-Miguel, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 2095–2097.
https://doi.org/10.1182/blood-2022-167382
Published: 2022
Journal Articles

Multiomics Profiling of Measurable Residual Disease (MRD) for Understanding the Biology of Ultra-Drug Resistance in Multiple Myeloma (MM)

Camila Guerrero, Noemi Puig, Maria Teresa Cedena Romero, Ibai Goicoechea, Leire Burgos, Diego Alignani, Aitziber Lopez, Sarai Sarvide, María José Calasanz, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, Laura Rosiñol, Esther González Garcia, Albert Oriol, Rafael Rios, Estrella Carrillo-Cruz, Marta Sonia Gonzalez Perez, Carmen Montes Gaisan, Felipe De Arriba, Jose Maria Arguiñano, Josep M Marti, Yolanda Gonzalez-Montes, Antonio Garcia-Guiñon, Juan-José Lahuerta, Joan Bladé Creixenti, Maria-Victoria Mateos, Jesús San-Miguel, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 246–248.
https://doi.org/10.1182/blood-2022-165402
Published: 2022
Journal Articles

Immune Biomarkers of Survival and Severe Infection in Newly Diagnosed Multiple Myeloma (NDMM) Patients (pts) Treated with the Backbone Regimen Lenalidomide and Dexamethasone (Rd)

Catarina Maia, Noemi Puig, Cristina Pérez Ruiz, Maria Teresa Cedena Romero, Camila Guerrero, Marta Larrayoz, Cirino Botta, Norma C. Gutierrez, María José Calasanz, Maria Luisa Martin-Ramos, Miguel Hernández, Laura Rosinol Dachs, Esther González Garcia, Felipe De Arriba, Albert Oriol, Veronica Gonzalez-Calle, Fernando Escalante, Javier de la Rubia, Mercedes Gironella Mesa, Rafael Rios, Ricarda Belen Garcia Sanchez, Jose Maria Arguiñano PEREZ, Adrian Alegre, Jesus Martin, María del Carmen Couto Caro, Maria Casanova, Mario Arnao Herraiz, Ernesto Pérez, Sebastián Garzón López, Marta Sonia Gonzalez Perez, Guillermo Martín-Nuñez, Adriana Rossi, Morton Coleman, Cristina Encinas, Ana M. Vale, Ana Isabel Teruel, María Cortés Rodríguez, Jose A. Martinez-Climent, Juan-José Lahuerta, Joan Bladé Creixenti, Ruben Niesvizky, Jesús San-Miguel, Maria-Victoria Mateos, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 4200–4203.
https://doi.org/10.1182/blood-2022-163058
Published: 2022
Journal Articles

Ixazomib Plus Lenalidomide/Dexamethasone (IRd) Versus Lenalidomide /Dexamethasone (Rd) Maintenance after Autologous Stem Cell Transplant in Patients with Newly Diagnosed Multiple Myeloma: Results of the Spanish GEM2014MAIN Trial

Laura Rosinol, Albert Oriol, Rafael Ríos Tamayo, María Jesús Blanchard, Isidro Jarque, Joan Bargay, Miguel-Teodoro Hernández, Jose Maria Moraleda, Estrella Carrillo-Cruz, Anna Sureda, Joaquín Martínez-López, Isabel Krsnik, Esther González Garcia, Felipe Casado, Josep M Marti, Cristina Encinas, Felipe De Arriba, Luis Palomera, Antonia Sampol, Yolanda Gonzalez-Montes, Elena Cabezudo, Maria-Victoria Mateos, Jesus San-Miguel, Juan Jose Lahuerta, Joan Bladé Creixenti
Journal: Blood
Blood (2021) 138 (Supplement 1): 466.
https://doi.org/10.1182/blood-2021-146798
Published: 2021
Journal Articles

Assessment of Treatment Response By Ife, Next Generation Flow Cytometry and Mass Spectrometry Coupled with Liquid Chromatography in the GEM2012MENOS65 Clinical Trial

Noemi Puig, Teresa Contreras Sanfeliciano, Bruno Paiva, María Teresa Cedena, Laura Rosinol, Ramón Garcia-Sanz, Joaquín Martínez-López, Albert Oriol, María Jesús Blanchard, Rafael Rios, Jesus Martin, Anna Sureda, Miguel Hernández, Javier De La Rubia, Isabel Krsnik, Jose Maria Moraleda, Belén Iñigo, Luis Palomera, Cristina Agulló, Joan Bargay, Joan Bladé Creixenti, Jesús San-Miguel, Juan-José Lahuerta, Maria-Victoria Mateos
Journal: Blood
Blood (2021) 138 (Supplement 1): 544.
https://doi.org/10.1182/blood-2021-151557
Published: 2021
Journal Articles

Definition and Clinical Significance of the MGUS-like Phenotype: A Study in 5,114 Patients (Pts) with Monoclonal Gammopathies

Leire Burgos, Luis Esteban Tamariz-Amador, Noemí Puig, María Teresa Cedena, Tomas Jelinek, Sarah K Johnson, Paolo Milani, Lourdes Cordon, José J Pérez, Marta Lasa, Rosalinda Termini, Albert Oriol, Miguel-Teodoro Hernández, Luis Palomera, Rafael Martinez Martinez, Javier de la Rubia, Felipe De Arriba, Rafael Rios, Maria Esther González, Mercedes Gironella, Valentin Cabañas, Maria Casanova, Isabel Krsnik, Albert Pérez, Veronica Gonzalez De La Calle, Paula Rodríguez-Otero, Vladimir Maisnar, Roman Hajek, Frits van Rhee, Victor H Jimenez-Zepeda, Giovanni Palladini, Paolo Milani, Alberto Orfao, Laura Rosinol, Joan Bladé Creixenti, Joaquín Martínez-López, Juan-José Lahuerta, Maria-Victoria Mateos, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (Supplement 1): 541.
https://doi.org/10.1182/blood-2021-150092
Published: 2021
Journal Articles

Prognostic Impact of MYD88 L265P Mutation By Droplet Digital PCR in IgM MGUS and Smoldering Waldenström Macroglobulinemia

David F. Moreno, Sara Paz, Mari-Pau Mena, Monica Lopez-Guerra, Aina Oliver-Caldes, Anthony M Battram, Luis Gerardo Rodríguez-Lobato, Natalia Tovar, M. Teresa Cibeira, Raquel Jiménez-Segura, Joan Bladé Creixenti, Laura Rosinol, Dolors Colomer, Carlos Fernandez de Larrea
Journal: Blood
Blood (2021) 138 (Supplement 1): 462.
https://doi.org/10.1182/blood-2021-147168
Published: 2021
Journal Articles

Selinexor in Combination with Daratumumab-Bortezomib and Dexamethasone for the Treatment of Relapse or Refractory Multiple Myeloma: Initial Results of the Phase 2, Open-Label, Multicenter GEM-Selibordara Study

Paula Rodríguez-Otero, Veronica Gonzalez De La Calle, Anna Sureda, Felipe De Arriba, Marta Reinoso Segura, Paz Ribas, Ana Pilar Gonzalez, Yolanda Gonzalez-Montes, Albert Oriol, Joaquín Martínez-López, Marta Sonia Gonzalez, Miguel T Hernández, Maialen Sirvent, Joan Bladé Creixenti, Juan Jose Lahuerta, Jesús F. San-Miguel, Maria-Victoria Mateos
Journal: Blood
Blood (2021) 138 (Supplement 1): 1677.
https://doi.org/10.1182/blood-2021-147725
Published: 2021
Journal Articles

Circulating Tumor Cells (CTCs) in Smoldering and Active Multiple Myeloma (MM): Mechanism of Egression, Clinical Significance and Therapeutic Endpoints

Juan-José Garcés, Noemi Puig, Rosalinda Termini, María Teresa Cedena, Cristina Moreno, José J Pérez, Diego Alignani, Sarvide Sarai, Albert Oriol, Esther González Garcia, Fernando Escalante, Anna Sureda, Felipe De Arriba, Rafael Rios, Jose Maria Moraleda, Mercedes Gironella, Miguel T Hernández, Juan Jose Joan Bargay, Luis Palomera, Alberto Orfao, Evangelos Terpos, Albert Pérez, Tomas Jelinek, Alexia Suárez, Hartmut Goldschmidt, Hervé Avet-Loiseau, Aldo M. Roccaro, Joaquin Martinez-Lopez, Juan Jose Lahuerta, Enrique Ocio, Laura Rosinol, Joan Bladé Creixenti, Maria-Victoria Mateos, Jesus San-Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (Supplement 1): 76.
https://doi.org/10.1182/blood-2021-146535
Published: 2021
Journal Articles

A Machine Learning Model Based on Tumor and Immune Biomarkers to Predict Undetectable Measurable Residual Disease (MRD) in Transplant-Eligible Multiple Myeloma (MM)

Camila Guerrero, Noemi Puig, María Teresa Cedena, Ibai Goicoechea, Cristina Pérez Ruiz, Juan José Garcés, Cirino Botta, Maria Jose Calasanz, Norma C. Gutierrez, Maria Luisa Martin-Ramos, Albert Oriol, Rafael Rios, Miguel Hernández, Rafael Martínez, Joan Bargay, Felipe De Arriba, Luis Palomera, Ana Pilar Gonzalez, Adrián Mosquera Orgueira, Marta Sonia Gonzalez, Joaquín Martínez-López, Juan Jose Lahuerta, Laura Rosinol, Joan Bladé Creixenti, Maria-Victoria Mateos, Jesus San-Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (Supplement 1): 1596.
https://doi.org/10.1182/blood-2021-145968
Published: 2021
Journal Articles

HORIZON (OP-106) Versus MAMMOTH: An Indirect Comparison of Efficacy Outcomes for Patients with Relapsed/Refractory Multiple Myeloma Refractory (RRMM) to Anti-CD38 Monoclonal Antibody Therapy Treated with Melflufen Plus Dexamethasone Versus Conventional Agents

Joan Blade Creixenti, María-Victoria Mateos, MD PhD, Albert Oriol, Alessandra Larocca, Michele Cavo, Paula Rodríguez-Otero, MD PhD, Xavier Leleu, MD, Maxim Norkin, MD PhD, Omar Nadeem, MD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Stojan Zavisic, BSc, Marcus Thuresson, PhD, Johan Harmenberg, MD PhD, Paul G. Richardson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–4.
https://doi.org/10.1182/blood-2020-137164
Published: 2020
Journal Articles

Randomized Phase 2 Study of Weekly Carfilzomib 70 Mg/m2 and Dexamethasone Plus/Minus Cyclophosphamide in Relapsed and/or Refractory Multiple Myeloma (RRMM) Patients (GEM-KyCyDex)

Maria-Victoria Mateos, MD PhD, Enrique M. Ocio, MDPhD, Anna Sureda Balari, MD PhD, Albert Oriol, Esther González Garcia, MD, Maria José Moreno, Miquel Granell, MD, Fernando Escalante, MD, Veronica Gonzalez De La Calle, MD PhD, Laura Rosinol Dachs, Estrella Carrillo-Cruz, MD, Joaquín Martínez-López, Maria Victoria Dourdil Sahun, Marta Sonia Gonzalez, MD, Jaime Perez De Oteyza, MDPhD, Felipe De Arriba, PhD, Miguel T Hernández, MD PhD, Aránzazu García Mateo, PhD, Ana Pilar Gonzalez, PhD, Rafael Rios, MD PhD, Carmen Cabrera, Juan Jose Bargay, Paula Rodriguez-Otero, MD, Felipe Casado, Maria Casanova, MD, María Jesús Blanchard, Joan Blade Creixenti, Juan Jose Lahuerta, MD PhD, Jesus F. San-Miguel, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-140934
Published: 2020