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Journal Articles

Down-Regulation of BMI-1 Is a New Marker of Sensitivity to Mdm2 Inhibition in B-Acute Lymphoblastic Leukemia.

Ilaria Iacobucci, Daniela Erriquez, Anna Ferrari, Cristina Papayannidis, Claudia Venturi, Stefania Trino, Viviana Guadagnuolo, Annalisa Lonetti, Federica Cattina, Emanuela Ottaviani, Maria Chiara Abbenante, Sarah Parisi, Simona Soverini, Domenico Russo, Fabrizio Pane, Michele Baccarani, MD, Giovanni Perini, Giovanni Martinelli
Journal: Blood
Blood (2012) 120 (21): 2522.
https://doi.org/10.1182/blood.V120.21.2522.2522
Published: 2012
Journal Articles

ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112

Ilaria Iacobucci, PhD, Federica Cattina, MD, Silvia Pomella, Annalisa Lonetti, Anna Ferrari, Cristina Papayannidis, Stefania Trino, Daniela Erriquez, Viviana Guadagnuolo, Emanuela Ottaviani, Serena Formica, Simona Soverini, Francesca Paoloni, Marco Vignetti, Domenico Russo, Giovanni Perini, Michele Baccarani, MD, Giovanni Martinelli, MD
Journal: Blood
Blood (2011) 118 (21): 2574.
https://doi.org/10.1182/blood.V118.21.2574.2574
Published: 2011
Journal Articles

Specific Drug Transporter Genotypes Are Significantly Associated with Increased Rates of Major and Complete Molecular Responses In Newly Diagnosed Chronic Myeloid Leukemia Patients Treated with Imatinib – A TOPS Correlative Substudy

Simona Soverini, Sabrina Angelini, Eleonora Turrini, Matt Burnett, Gloria Ravegnini, Mark Thornquist, Fabrizio Pane, MD, Fabrizio Quarantelli, Timothy P. Hughes, Deborah L. White, Dong-Wook Kim, MD, Harriet Goh, Jerald P. Radich, MD, Lan Beppu, Giuseppe Saglio, MD, PhD, Daniela Cilloni, Ilaria Iacobucci, Giovanni Perini, Giorgio Cantelli Forti, Gianantonio Rosti, Alan Hatfield, MD, Michele Baccarani, MD, Patrizia Hrelia, Giovanni Martinelli
Journal: Blood
Blood (2010) 116 (21): 670.
https://doi.org/10.1182/blood.V116.21.670.670
Published: 2010
Journal Articles

Suppression of Bcr-Abl Expression in CML by A Panel of miRNAs.

Nunzio Iraci, Ph.D., Emanuele Valli, Samuele Gherardi, Simona Soverini, PhD, Thea Kalebic, M.D., Michele Baccarani, M.D., Giovanni Martinelli, M.D., Giovanni Perini, Ph.D.
Journal: Blood
Blood (2009) 114 (22): 854.
https://doi.org/10.1182/blood.V114.22.854.854
Published: 2009
Journal Articles

IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients.

Ilaria Iacobucci, Monica Messina, Nunzio Iraci, Annalisa Lonetti, Sabina Chiaretti, Anna Ferrari, Cristina Papayannidis, Francesca Messa, PhD, Antonella Vitale, Francesca Paoloni, Daniela Cilloni, Clelia Tiziana Storlazzi, Emanuela Ottaviani, Stefania Paolini, Sandra Durante, Simona Soverini, Rita Guarini, Marco Vignetti, Fabrizio Pane, MD, Giuseppe Saglio, MD, Robin Foà, Markus Muschen, Heike Pfifer, Oliver Ottmann, MD, Giovanni Perini, Ph.D., Michele Baccarani, Giovanni Martinelli, MD
Journal: Blood
Blood (2009) 114 (22): 912.
https://doi.org/10.1182/blood.V114.22.912.912
Published: 2009
Journal Articles

C-Myc Mediated Regulation of Multidrug Resistance Genes in Chronic Myeloid Leukaemia Cd34+ Cell Progenitors.

Samuele Gherardi, Simona Soverini, Ph.D., Nunzio Iraci, Ph.D., Carolina Terragna, Ph.D., Emanuele Valli, Sandra Durante, Annalisa Astolfi, Ph.D., Roberto Bernardoni, Ph.D., Thea Kalebic, MD, Fabrizio Pane, MD, Giuseppe Saglio, MD, Giovanni Martinelli, MD, Michele Baccarani, MD, Giovanni Perini, Ph.D.
Journal: Blood
Blood (2009) 114 (22): 3252.
https://doi.org/10.1182/blood.V114.22.3252.3252
Published: 2009
Journal Articles

Association Between Imatinib (IM) Transporters and Metabolizing Enzymes Genotype and Response in Newly Diagnosed Chronic Myeloid Leukemia (CML) Patients (Pts) Is Influenced by Ethnicity.

Simona Soverini, PhD, Sabrina Angelini, Eleonora Turrini, Fabrizio Pane, MD, Fabrizio Quarantelli, Timothy P. Hughes, MD, MBBS, Deborah L White, PhD, Dong Wook Kim, Harriet Goh, Jerald Radich, Lan Beppu, Giuseppe Saglio, Daniela Cilloni, MD, Carolina Terragna, Sandra Durante, Ilaria Iacobucci, PhD, Giovanni Perini, Ph.D., Patrizia Hrelia, Giorgio Cantelli Forti, Thea Kalebic, MD, Matt Barnett, Mark Thornquist, Michele Baccarani, MD, Giovanni Martinelli
Journal: Blood
Blood (2009) 114 (22): 3283.
https://doi.org/10.1182/blood.V114.22.3283.3283
Published: 2009
Journal Articles

Expression Profiling of ABC Transporter Genes in Chronic Myeloid Leukemia (CML) and Responsiveness to Imatinib

Nunzio Iraci, Simona Soverini, Samuele Gherardi, Emanuele Valli, Fausto Castagnetti, Roberto Bernardoni, Gianantonio Rosti, Giuliano Della Valle, Francesca Palandri, Gabriele Gugliotta, Fabrizio Pane, Giuseppe Saglio, Nicola Esposito, Daniela Cilloni, Fabrizio Quarantelli, Enrico Gottardi, Michele Baccarani, Giovanni Martinelli, Giovanni Perini
Journal: Blood
Blood (2008) 112 (11): 3193.
https://doi.org/10.1182/blood.V112.11.3193.3193
Published: 2008
Journal Articles

Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance

Ilaria Iacobucci, Annalisa Lonetti, Francesca Messa, Daniela Cilloni, Francesca Arruga, Emanuela Ottaviani, Stefania Paolini, Cristina Papayannidis, Pier Paolo Piccaluga, Panagiota Giannoulia, Simona Soverini, Marilina Amabile, Angela Poerio, Giuseppe Saglio, Fabrizio Pane, Giorgio Berton, Anna Baruzzi, Antonella Vitale, Sabina Chiaretti, Giovanni Perini, Robin Foà, Michele Baccarani, Giovanni Martinelli
Journal: Blood
Blood (2008) 112 (9): 3847–3855.
https://doi.org/10.1182/blood-2007-09-112631
Published: 2008
Includes: Supplemental data
Journal Articles

Multidrug Resistance Gene (MDR1) Polymorphisms May Serve as Predictors of Resistance to Imatinib in Chronic Phase Chronic Myeloid Leukemia Patients.

Simona Soverini, Sabrina Angelini, Eleonora Turrini, Alessandra Gnani, Sabrina Colarossi, Giovanni Perini, Ilaria Iacobucci, Patrizia Hrelia, Giorgio Cantelli Forti, Daniela Cilloni, Giuseppe Saglio, Fabrizio Pane, Michele Baccarani, Thea Kalebic, Giovanni Martinelli
Journal: Blood
Blood (2007) 110 (11): 1946.
https://doi.org/10.1182/blood.V110.11.1946.1946
Published: 2007
Journal Articles

Direct and Coordinate Regulation of Multidrug Resistance Genes by the c-Myc Oncoprotein.

Antonio Porro, Simona Soverini, Daniel Diolaiti, Tiziana Grafone, Emanuela Ottaviani, Nunzio Iraci, Carolina Terragna, Thea Kalebic, Michele Baccarani, Giovanni Martinelli, Giuliano Della Valle, Giovanni Perini
Journal: Blood
Blood (2006) 108 (11): 2594.
https://doi.org/10.1182/blood.V108.11.2594.2594
Published: 2006