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Journal Articles

Dissecting the Molecular Mechanisms of Aneuploidy in Acute Myeloid Leukemia By Next Generation Sequencing

Giorgia Simonetti, PhD, Antonella Padella, Anna Ferrari, PhD, Viviana Guadagnuolo, PhD, Elisa Zago, PhD, Francesca Griggio, Marianna Garonzi, Simona Bernardi, Cristina Papayannidis, MD PhD, Stefania Paolini, Francesca Volpato, Emanuela Ottaviani, Margherita Bodini, Laura Riva, PhD, Serena Formica, Annalisa Astolfi, PhD, Carmen Baldazzi, PhD, Elisa Dan, Barbara Sinigaglia, Ilaria Iacobucci, PhD, Nicoletta Testoni, BSc, Daniel Remondini, PhD, Pier Giuseppe Pelicci, Raffaele Calogero, PhD, Alberto Ferrarini, PhD, Massimo Delledonne, PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2014) 124 (21): 1028.
https://doi.org/10.1182/blood.V124.21.1028.1028
Published: 2014
Journal Articles

The Novel Small Molecule Chk1/Chk2 Inhibitor PF-0477736 (Pfizer) Is Highly Active As Single Agent in Philadelphia-Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Ilaria Iacobucci, PhD, Federica Cattina, MD, Silvia Pomella, Annalisa Lonetti, Enrico Derenzini, MD, Elisa Brighenti, Anna Ferrari, Cristina Papayannidis, Maria Vittoria Verga Falzacappa, Viviana Guadagnuolo, Michela Aluigi, PhD, Emanuela Ottaviani, Serena Formica, Maria Chiara Abbenante, Simona Soverini, Domenico Russo, Fabrizio Pane, Pier Guiseppe Pellicci, Michele Baccarani, MD, Giovanni Martinelli
Journal: Blood
Blood (2011) 118 (21): 76.
https://doi.org/10.1182/blood.V118.21.76.76
Published: 2011
Journal Articles

ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112

Ilaria Iacobucci, PhD, Federica Cattina, MD, Silvia Pomella, Annalisa Lonetti, Anna Ferrari, Cristina Papayannidis, Stefania Trino, Daniela Erriquez, Viviana Guadagnuolo, Emanuela Ottaviani, Serena Formica, Simona Soverini, Francesca Paoloni, Marco Vignetti, Domenico Russo, Giovanni Perini, Michele Baccarani, MD, Giovanni Martinelli, MD
Journal: Blood
Blood (2011) 118 (21): 2574.
https://doi.org/10.1182/blood.V118.21.2574.2574
Published: 2011
Journal Articles

Gene expression analysis uncovers similarity and differences among Burkitt lymphoma subtypes

Pier Paolo Piccaluga, Giulia De Falco, Manjunath Kustagi, Anna Gazzola, Claudio Agostinelli, Claudio Tripodo, Eleonora Leucci, Anna Onnis, Annalisa Astolfi, Maria Rosaria Sapienza, Cristiana Bellan, Stefano Lazzi, Lynnette Tumwine, Michael Mawanda, Martin Ogwang, Valeria Calbi, Serena Formica, Andrea Califano, Stefano A. Pileri, Lorenzo Leoncini
Journal: Blood
Blood (2011) 117 (13): 3596–3608.
https://doi.org/10.1182/blood-2010-08-301556
Published: 2011
Includes: Supplemental data
Journal Articles

Identification of A Pharmacogenomic Profile Associated with High Sensitivity and Low Toxicity to a Combination of Gemtuzumab Ozogamicin Plus Fludarabine, Cytarabine, Idarubicin Regimen In CD33-Positive Acute Myeloid Leukemia (AML) Patients

Ilaria Iacobucci, Annalisa Lonetti, Anna Candoni, Marco Sazzini, Serena Formica, Emanuela Ottaviani, Anna Ferrari, Cristina Papayannidis, Angela Michelutti, Eleonora Toffoletti, Annalisa Astolfi, Stefania Paolini, Mariachiara Abbenante, Sarah Parisi, Domenico Russo, Daniela Damiani, Filippo Gherlinzoni, MD, Michele Gottardi, Michele Baccarani, MD, Renato Fanin, Giovanni Martinelli
Journal: Blood
Blood (2010) 116 (21): 967.
https://doi.org/10.1182/blood.V116.21.967.967
Published: 2010
Journal Articles

Gene Expression Analysis Uncovers Similarity and Differences Among Burkitt Lymphoma Subtypes

Pier Paolo Piccaluga, Giulia De Falco, Manjunat Kustagi, Anna Gazzola, Annalisa Astolfi, Claudio Agostinelli, Eleonora Leucci, Anna Onnis, Claudio Tripodo, maria Rosaria Sapienza, Cristiana Bellan, Stefano Lazzi, Lynnette Tumwine, Michael Mawanda, Martin Ogwang, Valeria Calbi, Serena Formica, Andrea Califano, PhD, Stefano Pileri, Lorenzo Leoncini
Journal: Blood
Blood (2010) 116 (21): 2494.
https://doi.org/10.1182/blood.V116.21.2494.2494
Published: 2010
Journal Articles

High-Resolution Genome Wide Copy Number Alteration (CNA) and Loss of Heterozigosity (LOH) Analysis in Chronic Myeloid Leukemia (CML) Shows That High and Intermediate Sokal Risk Pts (Pts) Have Multiple Losses Targeting Genes Involved in DNA Repair.

Simona Soverini, PhD, Sabrina Colarossi, Alessandra Gnani, Annalisa Astolfi, Serena Formica, Fausto Castagnetti, Francesca Palandri, Gabriele Gugliotta, Angela Poerio, Ilaria Iacobucci, Marilina Amabile, Giulia Marzocchi, Simona Luatti, Carolina Terragna, Sandra Durante, Nicoletta Testoni, Gianantonio Rosti, Michele Baccarani, Giovanni Martinelli
Journal: Blood
Blood (2009) 114 (22): 3262.
https://doi.org/10.1182/blood.V114.22.3262.3262
Published: 2009
Journal Articles

Whole-Transcriptome Sequencing of a Chronic Myeloid Leukemia (CML) Patient at Diagnosis and at the Time of Progression to Blast Crisis (BC).

Simona Soverini, PhD, Enrico Giacomelli, Alberto Ferrarini, Luciano Xumerle, Sabrina Colarossi, Alessandra Gnani, Fausto Castagnetti, Carolina Terragna, Sandra Durante, Annalisa Astolfi, Serena Formica, Giulia Marzocchi, Nicoletta Testoni, Ilaria Iacobucci, Angela Poerio, Francesca Palandri, Gabriele Gugliotta, Marilina Amabile, Gianantonio Rosti, Michele Baccarani, Massimo Delledonne, Giovanni Martinelli
Journal: Blood
Blood (2009) 114 (22): 4259.
https://doi.org/10.1182/blood.V114.22.4259.4259
Published: 2009
Journal Articles

High-Resolution Molecular Allelokaryotyping of Chronic Myeloid Leukemia Patients in Blast Crisis by 6.0 SNP-Arrays Shows a High-Frequency of Uniparental Disomy and Focal Copy Number Alterations Affecting the Whole Sequence or Specific Exons of Oncogenes and Tumor Suppressor Genes.

Simona Soverini, PhD, Sabrina Colarossi, Alessandra Gnani, Fausto Castagnetti, Annalisa Astolfi, Serena Formica, Francesca Palandri, Ilaria Iacobucci, Gabriele Gugliotta, Angela Poerio, Marilina Amabile, Giulia Marzocchi, Nicoletta Testoni, Elisabetta Abruzzese, Gianantonio Rosti, Michele Baccarani, Giovanni Martinelli
Journal: Blood
Blood (2009) 114 (22): 2176.
https://doi.org/10.1182/blood.V114.22.2176.2176
Published: 2009