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Journal Articles

Direct and Coordinate Regulation of Multidrug Resistance Genes by the c-Myc Oncoprotein.

Antonio Porro, Simona Soverini, Daniel Diolaiti, Tiziana Grafone, Emanuela Ottaviani, Nunzio Iraci, Carolina Terragna, Thea Kalebic, Michele Baccarani, Giovanni Martinelli, Giuliano Della Valle, Giovanni Perini

Blood (2006) 108 (11): 2594.

https://doi.org/10.1182/blood.V108.11.2594.2594

Published: 2006

Journal Articles

Up-Front Thalidomide-Dexamethasone (THAL) and Double Autologous Transplantation (Double TX) for Multiple Myeloma: Comparison with Double TX without Added Thalidomide and Prognostic Implications of Chromosome 13 Deletion and Translocation t(4;14).

Michele Cavo, Nicoletta Testoni, Carolina Terragna, Elena Zamagni, Paola Tacchetti, Chiara Nicci, Matteo Renzulli, Elena Montanari, Giulia Perrone, Delia Cangini, Tiziana Grafone, Michela Ceccolini, AnnaMaria Brioli, Giovanni Martinelli, Patrizia Tosi, Michele Baccarani

Blood (2006) 108 (11): 3081.

https://doi.org/10.1182/blood.V108.11.3081.3081

Published: 2006

Journal Articles

FIP1L1-PDGFRalpha Positive Hypereosinophilic Syndrome (HES). The Response to Imatinib (IM) Is Durable. A Report of 21 Patients with a Follow-Up of 12 to 67 Months.

Michela Rondoni, Emanuela Ottaviani, Pier Paolo Piccaluga, Stefania Paolini, Serena Merante, Daniela Cilloni, Michele Malagola, Michela Palmisano, Tiziana Grafone, Francesca Messa, Francesco Buccisano, Mario Tiribelli, Fabrizio Pane, Giuseppe Saglio, Giovanni Martinelli, Michele Baccarani

Blood (2006) 108 (11): 2700.

https://doi.org/10.1182/blood.V108.11.2700.2700

Published: 2006

Journal Articles

A Study of the Binding Mode and the In Vitro Activity of the Protein Tyrosine Kinase Inhibitor SKI-606 in the BCR-ABL Positive Cells.

Tiziana Grafone, Simona Soverini, Gianluca Tasco, Manuela Mancini, Frank Boschelli, Jennifer Golas, David Frauling, Sabrina Colarossi, Emanuela Ottaviani, Alessandra Gnani, Giannoulia Panagiota, Fausto Castagnetti, Rita Casadio, Gianantonio Rosti, Giovanni Martinelli, Michele Baccarani

Blood (2006) 108 (11): 2335.

https://doi.org/10.1182/blood.V108.11.2335.2335

Published: 2006

Journal Articles

FLT-3 Activity and Its Response to Drugs Can Be Determined in AML Blast Cells by FLT-3 Phosphorylation Status Using Flow Cytometry.

Tiziana Grafone, Michela Palmisano, Emanuela Ottaviani, Alberto Maria Martelli, Alessandra Cappellini, Matilde Follo, Nicoletta Testoni, Stefania Paolini, Michele Baccarani, Giovanni Martinelli

Blood (2006) 108 (11): 2308.

https://doi.org/10.1182/blood.V108.11.2308.2308

Published: 2006

Journal Articles

NPM Mutations and Not FLT3 Mutations Are a Potential Marker for Monitoring Minimal Residual Disease in Acute Myeloid Leukemia.

Michela Palmisano, Tiziana Grafone, Emanuela Ottaviani, Nicoletta Testoni, Stefania Paolini, Cristina Papayannidis, Michela Rondoni, Michele Baccarani, Giovanni Martinelli

Blood (2006) 108 (11): 2016.

https://doi.org/10.1182/blood.V108.11.2016.2016

Published: 2006

Journal Articles

Prevalence and Prognostic Significance of FLT3 Mutations in Acute Myeloid Leukemia: Association of ITDs with Poor Outcome in Patients with Normal Cytogenetics.

Michela Palmisano, Emanuela Ottaviani, Tiziana Grafone, Nicoletta Testoni, Stefania Paolini, Michela Rondoni, Michele Baccarani, Giovanni Martinelli

Blood (2006) 108 (11): 2017.

https://doi.org/10.1182/blood.V108.11.2017.2017

Published: 2006

Journal Articles

Prognostic Relevance of t(4;14) and Expression of FGFR3 and TACC3 in Newly Diagnosed Patients with Multiple Myeloma.

Carolina Terragna, Matteo Renzulli, Nicoletta Testoni, Chiara Nicci, Tiziana Grafone, Patrizia Tosi, Elena Zamagni, Claudia Cellini, Delia Cangini, Paola Tacchetti, Giulia Perrone, Simona Soverini, Giovanni Martinelli, Michele Baccarani, Michele Cavo

Blood (2005) 106 (11): 5072.

https://doi.org/10.1182/blood.V106.11.5072.5072

Published: 2005

Journal Articles

Gene Expression Profile in the CML Cell Line K562 Treated with SKI-606, a Dual Inhibitor of Src/Abl Kinase.

Matteo Renzulli, Tiziana Grafone, Cristian Taccioli, Carolina Terragna, Frank Boschelli, Manuela Mancini, Pasquale Creo, Emanuela Ottaviani, Sabrina Colarossi, Marilina Amabile, Simona Soverini, Angela Poerio, Ilaria Iacobucci, Michele Baccarani, Giovanni Martinelli

Blood (2005) 106 (11): 4870.

https://doi.org/10.1182/blood.V106.11.4870.4870

Published: 2005

Journal Articles

Better Molecular Response (MR) to Imatinib (IM) in Early Chronic Phase (CP) Versus Late CP Chronic Myeloid Leukemia (CML) Patients (pts) in Complete Cytogenetic Response (CCR): A Comparison at 24 Months of 2 Clinical Trials of the GIMEMA Working Party on CML on Behalf of the GIMEMA Working Party on Chronic Myeloid Leukemia (GIMEMA-CML).

Angela Poerio, Marilina Amabile, Ilaria Iacobucci, Simona Soverini, Sabrina Colarossi, Emanuela Ottaviani, Carolina Terragna, Tiziana Grafone, Simona Luatti, Fausto Castagnetti, Fabrizio Pane, Giuseppe Saglio, Domenico Russo, Gianantonio Rosti, Michele Baccarani, Giovanni Martinelli

Blood (2005) 106 (11): 1096.

https://doi.org/10.1182/blood.V106.11.1096.1096

Published: 2005

Journal Articles

Imatinib Mesylate Determines a High Frequency of Major Molecular Responses in Newly Diagnosed Philadelphia Chromosome-Positive Chronic Phase Chronic Myeloid Leukemia (CML) on Behalf of the GIMEMA Working Party on Chronic Myeloid Leukemia (GIMEMA-CML).

Ilaria Iacobucci, Nicoletta Testoni, Gianantonio Rosti, Marilina Amabile, Angela Poerio, Simona Soverini, Sabrina Colarossi, Alessandra Gnani, Emanuela Ottaviani, Fausto Castagnetti, Carolina Terragna, Matteo Renzulli, Tiziana Grafone, Daniela Cilloni, Fabrizio Pane, Giuseppe Saglio, Michele Baccarani, Giovanni Martinelli

Blood (2005) 106 (11): 1100.

https://doi.org/10.1182/blood.V106.11.1100.1100

Published: 2005

Journal Articles

A New Abl Kinase Inhibitor (AMN107) Has In Vitro Activity on Chronic Myeloid Leukaemia (CML) Ph+ Cells Resistant to Imatinib.

Giovanni Martinelli, Alberto M. Martelli, Tiziana Grafone, Irina Mantovani, Alessandra Cappellini, Pier Luigi Tazzari, Emanuela Ottaviani, Simona Soverini, Marilina Amabile, Matteo Renzulli, Carolina Terragna, Sabrina Colarossi, Ilaria Iacobucci, Angela Poerio, Michele Baccarani

Blood (2005) 106 (11): 2004.

https://doi.org/10.1182/blood.V106.11.2004.2004

Published: 2005

Journal Articles

Antiproliferative Effects of Tyrosine Kinase (STI 571) and Farnesyl Transferase Inhibitors (R115777 and SCH66336) on Acute Leukemia Human Tumor Cell Lines.

Domenico Russo, MD, Angela Michelutti, MD, Michele Malagola, MD, Tiziana Grafone, MD, Emanuela Ottaviani, MD, Anna Candoni, MD, Cristina Skert, MD, Carla Filì, MD, Maurizio Castelli, MD, Giovanni Martinelli, MD, Daniela Damiani, MD, Michele Baccarani, MD

Blood (2005) 106 (11): 4416.

https://doi.org/10.1182/blood.V106.11.4416.4416

Published: 2005

Journal Articles

SU11657, a FLT3-Targeted Tyrosine Kinase, Has Pro-Apoptotic Activity on Leukemia Cells In Vitro.

Tiziana Grafone, Laura Ferraretti, Emanuela Ottaviani, Manuela Mancini, Michela Palmisano, Michele Malagola, Carolina Terragna, Matteo Renzulli, Angela Poerio, Marilina Amabile, Simona Soverini, Sabrina Colarossi, Ilaria Iacobucci, Michele Baccarani, Giovanni Martinelli

Blood (2005) 106 (11): 2797.

https://doi.org/10.1182/blood.V106.11.2797.2797

Published: 2005

Journal Articles

Frequent Elevation of Akt Kinase Phosphorylation in Mononuclear Cells from High-Risk Myelodysplastic Syndrome Patients.

Costanza Bosi, MD, Carlo Finelli, MD, Alberto M. Martelli, MD, Maria Nyakern, Ph.D., Giovanni Martinelli, MD, Pier Luigi Tazzari, MD, Lucio Cocco, MD, Tiziana Grafone, PhD, Pier Paolo Piccaluga, MD, Baccarani Michele, MD

Blood (2005) 106 (11): 3432.

https://doi.org/10.1182/blood.V106.11.3432.3432

Published: 2005

Journal Articles

Superiority of thalidomide and dexamethasone over vincristine-doxorubicindexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma

Michele Cavo, Elena Zamagni, Patrizia Tosi, Paola Tacchetti, Claudia Cellini, Delia Cangini, Antonio de Vivo, Nicoletta Testoni, Chiara Nicci, Carolina Terragna, Tiziana Grafone, Giulia Perrone, Michela Ceccolini, Sante Tura, Michele Baccarani, for the writing committee of the Bologna 2002 study

Blood (2005) 106 (1): 35–39.

https://doi.org/10.1182/blood-2005-02-0522

Published: 2005

Journal Articles

A Novel 4-anilino-3-quinolinecarbonitrile Dual Src and Abl Kinase Inhibitor (SKI-606) Has In Vitro Activity on CML Ph+Blast Cells Resistant to Imatinib.

Tiziana Grafone, Manuela Mancini, Emanuela Ottaviani, Matteo Renzulli, Frank Boschelli, Laura Ferraretti, Maria Alessandra Santucci, Marilina Amabile, Simona Soverini, Carolina Terragna, Angela Poerio, Gianantonio Rosti, Cristian Taccioli, Michele Baccarani, Giovanni Martinelli

Blood (2004) 104 (11): 1991.

https://doi.org/10.1182/blood.V104.11.1991.1991

Published: 2004

Journal Articles

A New Abl Kinase Inhibitor (AMN107) Has In Vitro Activity on CML Ph+Blast Cells Resistant to Imatinib.

Giovanni Martinelli, Alberto M. Martelli, Tiziana Grafone, Gianantonio Rosti, Irina Mantovani, Alessandra Cappellini, Pier Luigi Tazzari, Emanuela Ottaviani, Matteo Renzulli, Marilina Amabile, Angela Poerio, Simona Soverini, Carolina Terragna, Cristian Taccioli, Simona Bassi, Michele Baccarani

Blood (2004) 104 (11): 4687.

https://doi.org/10.1182/blood.V104.11.4687.4687

Published: 2004

Journal Articles

Down Regulation of TOPK, PBX3, SRPK, DDX21 and CLC Genes in Newly Diagnosed, Early-Chronic Phase Chronic Myeloid Leukemia Patients Treated with Imatinib Mesylate.

Blood (2004) 104 (11): 4650.

https://doi.org/10.1182/blood.V104.11.4650.4650

Published: 2004

Journal Articles

Prediction of Response to Imatinib by Prospective Quantitation of BCR-ABL Transcript in Late Chronic Phase Chronic Myeloid Leukemia PatientsBy GIMEMA Working Party on CML.

Blood (2004) 104 (11): 4672.

https://doi.org/10.1182/blood.V104.11.4672.4672

Published: 2004

NARROW

Direct and Coordinate Regulation of Multidrug Resistance Genes by the c-Myc Oncoprotein.

Up-Front Thalidomide-Dexamethasone (THAL) and Double Autologous Transplantation (Double TX) for Multiple Myeloma: Comparison with Double TX without Added Thalidomide and Prognostic Implications of Chromosome 13 Deletion and Translocation t(4;14).

FIP1L1-PDGFRalpha Positive Hypereosinophilic Syndrome (HES). The Response to Imatinib (IM) Is Durable. A Report of 21 Patients with a Follow-Up of 12 to 67 Months.

A Study of the Binding Mode and the In Vitro Activity of the Protein Tyrosine Kinase Inhibitor SKI-606 in the BCR-ABL Positive Cells.

FLT-3 Activity and Its Response to Drugs Can Be Determined in AML Blast Cells by FLT-3 Phosphorylation Status Using Flow Cytometry.

NPM Mutations and Not FLT3 Mutations Are a Potential Marker for Monitoring Minimal Residual Disease in Acute Myeloid Leukemia.

Prevalence and Prognostic Significance of FLT3 Mutations in Acute Myeloid Leukemia: Association of ITDs with Poor Outcome in Patients with Normal Cytogenetics.

Prognostic Relevance of t(4;14) and Expression of FGFR3 and TACC3 in Newly Diagnosed Patients with Multiple Myeloma.

Gene Expression Profile in the CML Cell Line K562 Treated with SKI-606, a Dual Inhibitor of Src/Abl Kinase.

Imatinib Mesylate Determines a High Frequency of Major Molecular Responses in Newly Diagnosed Philadelphia Chromosome-Positive Chronic Phase Chronic Myeloid Leukemia (CML) on Behalf of the GIMEMA Working Party on Chronic Myeloid Leukemia (GIMEMA-CML).

A New Abl Kinase Inhibitor (AMN107) Has In Vitro Activity on Chronic Myeloid Leukaemia (CML) Ph+ Cells Resistant to Imatinib.

Antiproliferative Effects of Tyrosine Kinase (STI 571) and Farnesyl Transferase Inhibitors (R115777 and SCH66336) on Acute Leukemia Human Tumor Cell Lines.

SU11657, a FLT3-Targeted Tyrosine Kinase, Has Pro-Apoptotic Activity on Leukemia Cells In Vitro.

Frequent Elevation of Akt Kinase Phosphorylation in Mononuclear Cells from High-Risk Myelodysplastic Syndrome Patients.

Superiority of thalidomide and dexamethasone over vincristine-doxorubicindexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma

A Novel 4-anilino-3-quinolinecarbonitrile Dual Src and Abl Kinase Inhibitor (SKI-606) Has In Vitro Activity on CML Ph+Blast Cells Resistant to Imatinib.

A New Abl Kinase Inhibitor (AMN107) Has In Vitro Activity on CML Ph+Blast Cells Resistant to Imatinib.

Down Regulation of TOPK, PBX3, SRPK, DDX21 and CLC Genes in Newly Diagnosed, Early-Chronic Phase Chronic Myeloid Leukemia Patients Treated with Imatinib Mesylate.

Prediction of Response to Imatinib by Prospective Quantitation of BCR-ABL Transcript in Late Chronic Phase Chronic Myeloid Leukemia PatientsBy GIMEMA Working Party on CML.

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American Society of Hematology

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American Society of Hematology

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