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Alessandra Cappellini
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Journal Articles

Myeloid Differentiation in Myelodysplastic Neoplasms and Leukemic Cells: Role of Azacitidine and Direct Contact with Mesenchymal Stromal Cells

Eleonora Ceneri, Irene Casalin, Alessia De Stefano, Alessandra Cappellini, Lucio Cocco, Stefano Ratti, Lucia Manzoli, Michele Cavo, Miriam Fogli, Sarah Parisi, Stefania Paolini, Marilena Ciciarello, Antonio Curti, Carlo Finelli, Matilde Yung Follo
Journal: Blood
Blood (2024) 144 (Supplement 1): 6688.
https://doi.org/10.1182/blood-2024-204876
Published: 2024
Journal Articles

Investigating Phosphoinositide-Related and Apoptotic Pathways in Azacitidine and Venetoclax Combination Therapy in Higher-Risk Myelodysplastic Neoplasms and Leukemic Cell Lines

Irene Casalin, Eleonora Ceneri, Alessia De Stefano, Alessandra Cappellini, Andrea Pellagatti, Jacqueline Boultwood, Michele Cavo, Stefano Ratti, Lucia Manzoli, Lucio Cocco, Anna Ferrari, Giorgia Simonetti, Giovanni Martinelli, Miriam Fogli, Stefania Paolini, Sarah Parisi, Antonio Curti, Carlo Finelli, Matilde Yung Follo
Journal: Blood
Blood (2024) 144 (Supplement 1): 6686.
https://doi.org/10.1182/blood-2024-200842
Published: 2024
Journal Articles

Bone Marrow Microenvironment As a Potential Key Regulator of Hematopoietic Cells Stemness in Myelodysplastic Syndromes (MDS)

Irene Casalin, Alessia De Stefano, Alessandra Cappellini, Eleonora Ceneri, Martina Lops, Andrea Pellagatti, Jacqueline Boultwood, Michele Cavo, Stefano Ratti, Lucia Manzoli, Lucio Cocco, Marilena Ciciarello, Miriam Fogli, Stefania Paolini, Sarah Parisi, Antonio Curti, Carlo Finelli, Matilde Yung Follo
Journal: Blood
Blood (2023) 142 (Supplement 1): 6463.
https://doi.org/10.1182/blood-2023-179914
Published: 2023
Journal Articles

Venetoclax Rapidly and Strongly Enhances the Phospholipase C Response to Azacitidine Therapy in Myelodysplastic Syndromes

Matilde Y Follo, Alessia De Stefano, Sara Mongiorgi, Irene Casalin, Alessandra Cappellini, Stefano Ratti, Andrea Pellagatti, Miriam Fogli, Michele Cavo, Lucia Manzoli, Lucio Cocco, Jacqueline Boultwood, Sarah Parisi, Stefania Paolini, Antonio Curti, Carlo Finelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 6905–6906.
https://doi.org/10.1182/blood-2022-163628
Published: 2022
Journal Articles

The AKT Inhibitor, A443654, Induces Cell Cycle Arrest, Apoptosis and Synergizes with Chemotherapeutic Drugs in Multi-Drug Resistant T-Cell Acute Lymphoblastic Leukemia - A Novel Agent for Therapy of Drug Resistant ALL.

James A. McCubrey, PhD, William L. Blalock, PhD, Pier Luigi Tazzari, MD, Alessandra Cappellini, PhD, Ilaria Iacobucci, PhD, Francesca Chiarini, BS, Steve L. Abrams, BS, Emanuela Ottaviani, PhD, Giovanni Martinelli, MD, Agostino Tafuri, MD, Lucio Cocco, MD PhD, Alberto M. Martelli, MD PhD, Federica Fala, MD
Journal: Blood
Blood (2007) 110 (11): 3344.
https://doi.org/10.1182/blood.V110.11.3344.3344
Published: 2007
Journal Articles

The Novel Akt Inhibitor Perifosine Induces Apoptosis, Cell Cycle Arrest and Synergizes with Chemotherapeutic Drugs in Acute Myelogenous Leukemia Cells by a JNK Dependent Mechanism - A Novel Therapeutic Approach for Leukemia Displaying Elevated Akt Signaling.

Alberto M. Martelli, MD, PhD, Veronica Papa, BS, Pier Luigi Tazzari, MD, Francesca Chiarini, BS, Alessandra Cappellini, PhD, Francesca Ricci, BS, Anna Maria Billi, PhD, Camilla Evangelisti, PhD, Steve L. Abrams, BS, Emanuela Ottaviani, PhD, Giovanni Martinelli, MD, James A. McCubrey, PhD
Journal: Blood
Blood (2007) 110 (11): 3355.
https://doi.org/10.1182/blood.V110.11.3355.3355
Published: 2007
Journal Articles

FLT-3 Activity and Its Response to Drugs Can Be Determined in AML Blast Cells by FLT-3 Phosphorylation Status Using Flow Cytometry.

Tiziana Grafone, Michela Palmisano, Emanuela Ottaviani, Alberto Maria Martelli, Alessandra Cappellini, Matilde Follo, Nicoletta Testoni, Stefania Paolini, Michele Baccarani, Giovanni Martinelli
Journal: Blood
Blood (2006) 108 (11): 2308.
https://doi.org/10.1182/blood.V108.11.2308.2308
Published: 2006
Journal Articles

A New Abl Kinase Inhibitor (AMN107) Has In Vitro Activity on Chronic Myeloid Leukaemia (CML) Ph+ Cells Resistant to Imatinib.

Giovanni Martinelli, Alberto M. Martelli, Tiziana Grafone, Irina Mantovani, Alessandra Cappellini, Pier Luigi Tazzari, Emanuela Ottaviani, Simona Soverini, Marilina Amabile, Matteo Renzulli, Carolina Terragna, Sabrina Colarossi, Ilaria Iacobucci, Angela Poerio, Michele Baccarani
Journal: Blood
Blood (2005) 106 (11): 2004.
https://doi.org/10.1182/blood.V106.11.2004.2004
Published: 2005
Journal Articles

A New Abl Kinase Inhibitor (AMN107) Has In Vitro Activity on CML Ph+Blast Cells Resistant to Imatinib.

Giovanni Martinelli, Alberto M. Martelli, Tiziana Grafone, Gianantonio Rosti, Irina Mantovani, Alessandra Cappellini, Pier Luigi Tazzari, Emanuela Ottaviani, Matteo Renzulli, Marilina Amabile, Angela Poerio, Simona Soverini, Carolina Terragna, Cristian Taccioli, Simona Bassi, Michele Baccarani
Journal: Blood
Blood (2004) 104 (11): 4687.
https://doi.org/10.1182/blood.V104.11.4687.4687
Published: 2004