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Marilena Ciciarello
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Journal Articles

Myeloid Differentiation in Myelodysplastic Neoplasms and Leukemic Cells: Role of Azacitidine and Direct Contact with Mesenchymal Stromal Cells

Eleonora Ceneri, Irene Casalin, Alessia De Stefano, Alessandra Cappellini, Lucio Cocco, Stefano Ratti, Lucia Manzoli, Michele Cavo, Miriam Fogli, Sarah Parisi, Stefania Paolini, Marilena Ciciarello, Antonio Curti, Carlo Finelli, Matilde Yung Follo
Journal: Blood
Blood (2024) 144 (Supplement 1): 6688.
https://doi.org/10.1182/blood-2024-204876
Published: 2024
Journal Articles

Interferon-Gamma Production By Dysplastic Cells Supports an Immune-Tolerant Bone Marrow Microenvironment in Myelodysplastic Syndrome Patients

Marilena Ciciarello, Francesca Girotti, Darina Ocadlikova, Letizia Zannoni, Federica Ardizzoia, Cecilia Evangelisti, Cesare Rossi, Michele Cavo, Antonio Curti
Journal: Blood
Blood (2024) 144 (Supplement 1): 6687.
https://doi.org/10.1182/blood-2024-203447
Published: 2024
Journal Articles

T/NK Cell-Associated Transcriptomic Profile Informs Response to FLT3 Inhibitors in Acute Myeloid Leukemia

Jacopo Nanni, Jayakumar Vadakekolathu, Lorenza Bandini, Marilena Ciciarello, Karyna Volkava, Samantha Bruno, Valentina Robustelli, Letizia Zannoni, Chiara Sartor, Gianluca Cristiano, Federico Zingarelli, Andrea Davide Romagnoli, Caterina Azzimondi, Federica Ardizzoia, Raffaele Ciruolo, Giovanni Marconi, Claudia Venturi, Ajsi Kanapari, Gaia Mazzocchetti, Giorgia Simonetti, Martina Ghetti, Nicoletta Testoni, Sarah Parisi, Stefania Paolini, Simona Soverini, Emanuela Ottaviani, Cristina Papayannidis, Michele Cavo, Sergio Rutella, Antonio Curti
Journal: Blood
Blood (2024) 144 (Supplement 1): 2916.
https://doi.org/10.1182/blood-2024-205994
Published: 2024
Journal Articles

Bone Marrow Microenvironment As a Potential Key Regulator of Hematopoietic Cells Stemness in Myelodysplastic Syndromes (MDS)

Irene Casalin, Alessia De Stefano, Alessandra Cappellini, Eleonora Ceneri, Martina Lops, Andrea Pellagatti, Jacqueline Boultwood, Michele Cavo, Stefano Ratti, Lucia Manzoli, Lucio Cocco, Marilena Ciciarello, Miriam Fogli, Stefania Paolini, Sarah Parisi, Antonio Curti, Carlo Finelli, Matilde Yung Follo
Journal: Blood
Blood (2023) 142 (Supplement 1): 6463.
https://doi.org/10.1182/blood-2023-179914
Published: 2023
Journal Articles

T Cell/Natural Killer (NK) Cell Transcriptional Profiles Are Associated with Response to Gilteritinib in FLT3 -Mutated Acute Myeloid Leukemia

Jacopo Nanni, Jayakumar Vadakekolathu, Lorenza Bandini, Samantha Bruno, Letizia Zannoni, Chiara Sartor, Gianluca Cristiano, Sarah Parisi, Federico Zingarelli, Raffaele Ciruolo, Giovanni Marconi, Claudia Venturi, Marilena Ciciarello, Aisi Kanapari, Gaia Mazzocchetti, Giorgia Simonetti, Martina Ghetti, Nicoletta Testoni, Stefania Paolini, Simona Soverini, Emanuela Ottaviani, Cristina Papayannidis, Michele Cavo, Sergio Rutella, Antonio Curti
Journal: Blood
Blood (2023) 142 (Supplement 1): 2947.
https://doi.org/10.1182/blood-2023-184741
Published: 2023
Journal Articles

Mesenchymal Stromal Cells Protect Acute Myeloid Leukemia Cells from Venetoclax-Induced Apoptosis through Contact-Dependent Mechanisms

Giulia Corradi, Samantha Bruno, Gaia Mazzocchetti, Jacopo Nanni, Andrea Polimeno, Michele Cavo, Marilena Ciciarello, Antonio Curti
Journal: Blood
Blood (2022) 140 (Supplement 1): 11424–11425.
https://doi.org/10.1182/blood-2022-166792
Published: 2022
Journal Articles

A Three-Gene Immune Signature Including IDO1 , BIN1 and PLXNC1 Predicts Survival in Acute Myeloid Leukemia

Simone Ragaini, MD, Sarah Wagner, BSc MSc, Giovanni Marconi, MD, Sarah Parisi, MDPhD, Chiara Sartor, MD, Jacopo Nanni, MD, Gianluca Cristiano, MD, Annalisa Talami, MD, Matteo Olivi, MD, Darina Ocadlikova, PhD, Marilena Ciciarello, PhD, Giulia Corradi, PhD, Emanuela Ottaviani, Cristina Papayannidis, MDPhD, Stefania Paolini, MD PhD, Jayakumar Vadakekolathu, PhD, Michele Cavo, Sergio Rutella, MDPhDFRCPath, Antonio Curti, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–36.
https://doi.org/10.1182/blood-2020-139665
Published: 2020
Journal Articles

Interferon-γ-Dependent Inflammatory Signature in Acute Myeloid Leukemia Cells Is Able to Shape Stromal and Immune Bone Marrow Microenvironment

Marilena Ciciarello, PhD, Giulia Corradi, PhD, Sabina Sangaletti, PhD, Barbara Bassani, Giorgia Simonetti, PhD, Jayakumar Vadakekolathu, PhD, Giovanni Marconi, Giovanni Martinelli, MD, Mario Paolo Colombo, Sergio Rutella, MDPhDFRCPath, Michele Cavo, Antonio Curti, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1212.
https://doi.org/10.1182/blood-2019-126512
Published: 2019
Journal Articles

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Simone Ragaini, MD, Sarah Wagner, BSc MSc, Giovanni Marconi, Sarah Parisi, MD PhD, Chiara Sartor, MD, Jacopo Nanni, MD, Gianluca Cristiano, Annalisa Talami, MD, Matteo Olivi, MD, Darina Ocadlikova, PhD, Marilena Ciciarello, PhD, Giulia Corradi, PhD, Emanuela Ottaviani, Cristina Papayannidis, Stefania Paolini, MD PhD, Jayakumar Vadakekolathu, PhD, Michele Cavo, Sergio Rutella, MD PhD FRCPath, Antonio Curti, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5193.
https://doi.org/10.1182/blood-2019-128348
Published: 2019
Journal Articles

Up-Regulation of Immune Tolerance Genes in Leukemic Mesenchymal Stromal Cells Is Induced By Acute Myeloid Leukemia Cells through an IFN-Gamma-Dependent Inflammatory Signaling

Marilena Ciciarello, PhD, Giulia Corradi, BS, Giorgia Simonetti, PhD, Giovanni Marconi, Sabina Sangaletti, PhD, Mario Paolo Colombo, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti
Journal: Blood
Blood (2018) 132 (Supplement 1): 2579.
https://doi.org/10.1182/blood-2018-99-112497
Published: 2018
Journal Articles

Bitter Taste Receptors System Is Expressed and Functional in Both HSCs and Leukemic Cells

Valentina Salvestrini, PhD, Valentina Pensato, Marilena Ciciarello, PhD, Giorgia Simonetti, PhD, Dorian Forte, Simon Mendez-Ferrer, PhD, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti
Journal: Blood
Blood (2018) 132 (Supplement 1): 2560.
https://doi.org/10.1182/blood-2018-99-111806
Published: 2018
Journal Articles

Bitter Taste Receptors Are Expressed on Acute Myeloid Leukemia Cells and Their Activation Results in Quiescence Induction and Prevention of Migration

Valentina Salvestrini, PhD, Marilena Ciciarello, Giorgia Simonetti, PhD, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3949.
https://doi.org/10.1182/blood.V130.Suppl_1.3949.3949
Published: 2017
Journal Articles

Upregulation of Indoleamine 2,3-Dioxygenase Enzymes in Leukemic Mesenchymal Stromal Cells (MSCs) Can Influence MSC/Acute Myeloid Leukemia Cell Cross Talk

Marilena Ciciarello, PhD, Giulia Corradi, PhDstudent, Carmen Baldazzi, PhD, Nicoletta Testoni, Professor, Roberto Massimo Lemoli, MD, Michele Cavo, Antonio Curti, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1191.
https://doi.org/10.1182/blood.V126.23.1191.1191
Published: 2015
Journal Articles

Human Blood Dendritic Cells Induce Tregs Through the PGE2-Independent Expression of an Active Form of IDO2 Enzyme

Sara Trabanelli, Darina Ocadlikova, Marilena Ciciarello, Valentina Salvestrini, Cecilia Evangelisti, Richard Metz, Lisa Laury-Kleintop, George Prendergast, Antonio Curti, MD, Roberto M. Lemoli
Journal: Blood
Blood (2012) 120 (21): 1047.
https://doi.org/10.1182/blood.V120.21.1047.1047
Published: 2012
Journal Articles

PGE 2 -Independent Expression of Indoleamine 2,3-Dioxygenase-2 (IDO2) Supports the Tolerogenic Function of Monocyte-Derived Dendritic Cells,

Sara Trabanelli, Antonio Curti, MD, Darina Ocadlikova, Cecilia Evangelisti, Valentina Salvestrini, Marilena Ciciarello, Michela Aluigi, PhD, Lara Rossi, Richard Metz, Lisa Laury-Kleintop, George Prendergast, Roberto M. Lemoli, MD
Journal: Blood
Blood (2011) 118 (21): 3231.
https://doi.org/10.1182/blood.V118.21.3231.3231
Published: 2011
Journal Articles

Integrin Alpha E (CD103) Beta 7 Expression Marks A Subset of Human Bone Marrow-Derived CD207 + Dendritic Cells Which Induce T Regulatory Cells Via Indoleamine 2,3-Dioxygenase,

Antonio Curti, MD, Darina Ocadlikova, Sara Trabanelli, Cecilia Evangelisti, Marilena Ciciarello, Michele Baccarani, MD, Roberto M. Lemoli, MD
Journal: Blood
Blood (2011) 118 (21): 3233.
https://doi.org/10.1182/blood.V118.21.3233.3233
Published: 2011
Journal Articles

Purinergic Stimulation of Human Bone Marrow-Derived Mesenchymal Stem Cells Modulate Their Function and Differentiation Potential.

Marilena Ciciarello, Valentina Salvestrini, Davide Ferrari, Sara Gulinelli, Roberta Zini, Rossella Manfredini, Luisa Caione, Wanda Piacibello, MD, Giovanna Lucchetti, Lara Rossi, Sergio Ferrari, Francesco Di Virgilio, Roberto M. Lemoli, MD
Journal: Blood
Blood (2010) 116 (21): 3848.
https://doi.org/10.1182/blood.V116.21.3848.3848
Published: 2010
Journal Articles

Purinergic Signaling Modulates Human Bone Marrow-Derived Mesenchymal Stem Cells Function.

Valentina Salvestrini, BS, Davide Ferrari, PhD, Sara Gulinelli, BS, Luisa Caione, BS, Wanda Piacibello, MD, Roberta Zini, BS, Marilena Ciciarello, PhD, Rossella Manfredini, PhD, Giovanna Lucchetti, BS, Sergio Ferrari, MD, Francesco Di Virgilio, MD, Roberto M Lemoli, MD
Journal: Blood
Blood (2009) 114 (22): 1441.
https://doi.org/10.1182/blood.V114.22.1441.1441
Published: 2009