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Journal Articles

Bortezomib-Thalidomide-Dexamethasone Compared with Thalidomide-Dexamethasone as Induction and Consolidation Therapy Before and After Double Autologous Transplantation In Newly Diagnosed Multiple Myeloma: Results From a Randomized Phase 3 Study

Blood (2010) 116 (21): 42.

https://doi.org/10.1182/blood.V116.21.42.42

Published: 2010

Journal Articles

Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma

Güllü Görgün, Elisabetta Calabrese, Ender Soydan, Teru Hideshima, Giulia Perrone, Madhavi Bandi, Diana Cirstea, Loredana Santo, Yiguo Hu, Yu-Tzu Tai, Sabikun Nahar, Naoya Mimura, Claire Fabre, Noopur Raje, Nikhil Munshi, Paul Richardson, Kenneth C. Anderson

Blood (2010) 116 (17): 3227–3237.

https://doi.org/10.1182/blood-2010-04-279893

Published: 2010

Includes: Supplemental data

Journal Articles

PI3K/p110δ is a novel therapeutic target in multiple myeloma

Blood (2010) 116 (9): 1460–1468.

https://doi.org/10.1182/blood-2009-06-222943

Published: 2010

Includes: Supplemental data

Journal Articles

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

Blood (2010) 115 (25): 5202–5213.

https://doi.org/10.1182/blood-2009-12-259523

Published: 2010

Includes: Supplemental data

Journal Articles

Preclinical Approach to Sensitize Multiple Myeloma Cells: Combination of the MEK Inhibitor PD0325901 with ABT-737 or Mevinolin.

Maria Rosaria Ricciardi, Elisabetta Calabrese, Michele Milella, Paola Bergamo, Samantha Decandia, Cinzia De Benedictis, Robin Foà, Agostino Tafuri, Maria Teresa Petrucci

Blood (2009) 114 (22): 1842.

https://doi.org/10.1182/blood.V114.22.1842.1842

Published: 2009

Journal Articles

A NOVEL Aurora A Kinase INHIBITOR MLN8237 Induces Cytotoxicity and CELL Cycle Arrest IN MULTIPLE MYELOMA.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Teru Hideshima, MD, PhD, Jeffrey Ecsedy, PhD, Giada Bianchi, MD, Mala Mani, PhD, Madhavi Bandi, Hiroshi Ikeda, MD, PhD, Giulia Perrone, MD, Yiguo Hu, MD, PhD, Yu-Tzu Tai, PhD, Mei Zheng, Diana Cristea, MD, Loredana Santo, MD, Daniel R. Carrasco, MD, PhD, Nikhil Munshi, MD, Paul Richardson, MD, Kenneth C. Anderson, MD

Blood (2009) 114 (22): 3830.

https://doi.org/10.1182/blood.V114.22.3830.3830

Published: 2009

Journal Articles

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor Induces Antimyeloma Activity Via Potent Aurora Kinase and STAT3 Inhibition.

Loredana Santo, M.D., Teru Hideshima, MD., Ph.D., Erik A. Nelson, Ph.D, Diana Cirstea, MD, Madhavi Bandi, Ph.D, Hiroshi Ikeda, MD, PhD, Gullu Gorgun, PhD, Sonia Vallet, MD., Samantha Pozzi, MD, Giulia Perrone, MD, Kishan Patel, Yiguo Hu, Ph.D, Matthew S Squires, Murray Yule, Elisabetta Calabrese, MD., Dharminder Chauhan, Ph.D, Nikhil C. Munshi, Kenneth C. Anderson, MD, Noopur Raje, MD.

Blood (2009) 114 (22): 3833.

https://doi.org/10.1182/blood.V114.22.3833.3833

Published: 2009

Journal Articles

Immunomodulatory EFFECTS of Lenalidomide and Pomalidomide ON INTERACTION of TUMOR and BONE MARROW Accessory CELLS IN MULTIPLE MYELOMA.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Teru Hideshima, MD, PhD, Giulia Perrone, MD, Giada Bianchi, MD, Hiroshi Ikeda, MD, PhD, Mala Mani, PhD, Yiguo Hu, MD, PhD, Diana Cristea, MD, Loredana Santo, MD, Yu-Tzu Tai, PhD, Nikhil Munshi, MD, Paul Richardson, MD, Kenneth C. Anderson, MD

Blood (2009) 114 (22): 950.

https://doi.org/10.1182/blood.V114.22.950.950

Published: 2009

Journal Articles

Panobinostat Inhibits JAK2/STAT3 Pathway in Multiple Myeloma.

Giulia Perrone, MD, Elisabetta Calabrese, MD., Teru Hideshima, M.D., Ph.D., Gullu Gorgun, PhD,, Ikeda Hiroshi, Diana Cristea, Loredana Santo, Hu Yiguo, Kenneth C. Anderson, MD

Blood (2009) 114 (22): 2849.

https://doi.org/10.1182/blood.V114.22.2849.2849

Published: 2009

Journal Articles

BCL-2/BCL-XL Inhibition in Smoldering Multiple Myeloma CD138+ Cells: Functional Effects and Protein Expression Levels

Francesco Libotte, Maria Rosaria Ricciardi, Elisabetta Calabrese, Cinzia De Benedictis, Sara Santinelli, Paola Bergamo, Samantha Decandia, Anna Levi, Ali Fathi Mohamad, Vincenzo Federico, Michele Milella, Robert Foà, Agostino Tafuri, Maria Teresa Petrucci

Blood (2008) 112 (11): 5159.

https://doi.org/10.1182/blood.V112.11.5159.5159

Published: 2008

Journal Articles

Synergistic Induction of Apoptosis in Multiple Myeloma Cells by Simultaneous Inhibition of the Raf/MEK/ERK and BCL-2 Pathways

Maria Rosaria Ricciardi, Michele Milella, Francesco Libotte, Elisabetta Calabrese, Paola Bergamo, Sara Santinelli, Samantha Decandia, Cinzia De Benedictis, Anna Levi, Robert Foà, Agostino Tafuri, Maria Teresa Petrucci

Blood (2008) 112 (11): 5161.

https://doi.org/10.1182/blood.V112.11.5161.5161

Published: 2008

Journal Articles

RGB 286638, a Novel Multi-Targeted Small Molecule Inhibitor, Induces Multiple Myeloma (MM) Cell Death through Abrogation of CDKDependent and Independent Survival Mechanisms

Diana Cirstea, M.D., Teru Hideshima, M.D., Ph.D., Samantha Pozzi, M.D., Sonia Vallet, M.D., Hiroshi Ikeda, M.D., Ph.D., Loredana Santo, M.D., Hannes Loferer, Nileshwari Vaghela, M.B.S., Yutaka Okawa, M.D., Ph.D., Giulia Perrone, M.D., Gullu Gorgun, Ph.D., Elisabetta Calabrese, M.D., Nikhil C. Munshi, MD, Kenneth C. Anderson, M.D., Noopur Raje, M.D.

Blood (2008) 112 (11): 2759.

https://doi.org/10.1182/blood.V112.11.2759.2759

Published: 2008

Journal Articles

Melphalan 200 Mg/m 2 (Mel200) Versus Melphalan 100 Mg/m 2 (Mel100) in Newly Diagnosed Myeloma Patients: A Prospective, Randomized Phase III Study

Blood (2008) 112 (11): 3316.

https://doi.org/10.1182/blood.V112.11.3316.3316

Published: 2008

Journal Articles

Combination of Nab -Rapamycin and Perifosine Induces Synergistic Cytotoxicity and Antitumor Activity Via Autophagy and Apoptosis in Multiple Myeloma (MM)

Blood (2008) 112 (11): 3663.

https://doi.org/10.1182/blood.V112.11.3663.3663

Published: 2008

Journal Articles

The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Potent and Selective Cytotoxicity against CD138 Positive Multiple Myeloma Cells in Vitro and in Vivo.

Blood (2008) 112 (11): 1716.

https://doi.org/10.1182/blood.V112.11.1716.1716

Published: 2008

Journal Articles

A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Mala Mani, PhD, Teru Hideshima, M.D., Ph.D., Hiroshi Ikeda, MD, PhD, Giulia Perrone, MD, Loredana Santo, MD, Diana Cirstea, MD, Simona Blotta, Paul G. Richardson, MD, Jeffrey Ecsedy, Kenneth C. Anderson, MD

Blood (2008) 112 (11): 1719.

https://doi.org/10.1182/blood.V112.11.1719.1719

Published: 2008

Journal Articles

Immunomodulatory Effects of Lenalidomide and Bortezomib on Bone Marrow Stroma Cell and CD4 T Cell Interaction in Multiple Myeloma.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Teru Hideshima, Hiroshi Ikeda, Giulia Perrone, Loredana Santo, Diana Cirstea, Paul G Richardson, Kenneth C Anderson

Blood (2008) 112 (11): 1690.

https://doi.org/10.1182/blood.V112.11.1690.1690

Published: 2008

Journal Articles

Dietary Supplement Vitamin C Significantly Abrogates Bortezomib-Induced Multiple Myeloma (MM) Cell Growth Inhibition

Giulia Perrone, Teru Hideshima, MD, PhD, Hiroshi Ikeda, Yutaka Okawa, Diana Cristea, Loredana Santo, Gullu Gorgun, Elisabetta Calabrese, Noopur Raje, Michele Baccarani, Michele Cavo, Kenneth C. Anderson, MD

Blood (2008) 112 (11): 3687.

https://doi.org/10.1182/blood.V112.11.3687.3687

Published: 2008

Journal Articles

AT7519, a Novel Small Molecule Multi-Cyclin Dependent Kinase Inhibitor, Induces Apoptosis in Multiple Myeloma VIA GSK3β

Loredana Santo, MD, Sonia Vallet, M.D., Teru Hideshima, M.D., Ph.D., Diana Cirstea, MD, Samantha Pozzi, MD, Nileshwari Vaghela, Hiroshi Ikeda, MD, PhD, Yutaka Okawa, MD, Gullu Gorgun, PhD, Giulia Perrone, MD, Elisabetta Calabrese, MD, Matthew S Squires, Marco Ladetto, MD, Nikhil C. Munshi, MD, Mario Boccadoro, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2008) 112 (11): 251.

https://doi.org/10.1182/blood.V112.11.251.251

Published: 2008

Journal Articles

Economic and Social Burden of Multiple Myeloma in Italy: The Co.Mi.M. Study

Maria Teresa Petrucci, Elisabetta Calabrese, Anna Levi, Vincenzo Federico, Michela Ceccolini, Rita Rizzi, Alessandro Gozzetti, Patrizia Falco, Maria Caterina Cavallo, Simone Gerzelli, Mario Boccadoro, Francesco Lauria, Vincenzo Liso, Michele Cavo, Robert Foa

Blood (2008) 112 (11): 2393.

https://doi.org/10.1182/blood.V112.11.2393.2393

Published: 2008

NARROW

Bortezomib-Thalidomide-Dexamethasone Compared with Thalidomide-Dexamethasone as Induction and Consolidation Therapy Before and After Double Autologous Transplantation In Newly Diagnosed Multiple Myeloma: Results From a Randomized Phase 3 Study

Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma

PI3K/p110δ is a novel therapeutic target in multiple myeloma

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

Preclinical Approach to Sensitize Multiple Myeloma Cells: Combination of the MEK Inhibitor PD0325901 with ABT-737 or Mevinolin.

A NOVEL Aurora A Kinase INHIBITOR MLN8237 Induces Cytotoxicity and CELL Cycle Arrest IN MULTIPLE MYELOMA.

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor Induces Antimyeloma Activity Via Potent Aurora Kinase and STAT3 Inhibition.

Immunomodulatory EFFECTS of Lenalidomide and Pomalidomide ON INTERACTION of TUMOR and BONE MARROW Accessory CELLS IN MULTIPLE MYELOMA.

Panobinostat Inhibits JAK2/STAT3 Pathway in Multiple Myeloma.

BCL-2/BCL-XL Inhibition in Smoldering Multiple Myeloma CD138+ Cells: Functional Effects and Protein Expression Levels

Synergistic Induction of Apoptosis in Multiple Myeloma Cells by Simultaneous Inhibition of the Raf/MEK/ERK and BCL-2 Pathways

RGB 286638, a Novel Multi-Targeted Small Molecule Inhibitor, Induces Multiple Myeloma (MM) Cell Death through Abrogation of CDKDependent and Independent Survival Mechanisms

Melphalan 200 Mg/m 2 (Mel200) Versus Melphalan 100 Mg/m 2 (Mel100) in Newly Diagnosed Myeloma Patients: A Prospective, Randomized Phase III Study

Combination of Nab -Rapamycin and Perifosine Induces Synergistic Cytotoxicity and Antitumor Activity Via Autophagy and Apoptosis in Multiple Myeloma (MM)

The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Potent and Selective Cytotoxicity against CD138 Positive Multiple Myeloma Cells in Vitro and in Vivo.

A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models.

Immunomodulatory Effects of Lenalidomide and Bortezomib on Bone Marrow Stroma Cell and CD4 T Cell Interaction in Multiple Myeloma.

Dietary Supplement Vitamin C Significantly Abrogates Bortezomib-Induced Multiple Myeloma (MM) Cell Growth Inhibition

AT7519, a Novel Small Molecule Multi-Cyclin Dependent Kinase Inhibitor, Induces Apoptosis in Multiple Myeloma VIA GSK3β

Economic and Social Burden of Multiple Myeloma in Italy: The Co.Mi.M. Study

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