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Naoya Mimura
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Journal Articles

Preemptive Intervention in Airflow Obstruction Status Prevents the Development of Bronchiolitis Obliterans Syndrome after Allogeneic Stem Cell Transplantation: Multicenter, Prospective Phase II Study (Chiba AFO-01)

Shokichi Tsukamoto, Kenji Kimura, Sanshiro Nakao, Yusuke Takeda, Chikako Ohwada, Ryo Shimizu, Yuhei Nagao, Katsuhiro Shono, Masahiro Onoda, Akira Yokota, Hironori Arai, Yoshikazu Utsu, Shinichi Masuda, Nobuyuki Aotsuka, Yuki Shiko, Yoshihito Ozawa, Arata Ishii, Shinichiro Matsui, Koji Takaishi, Yutaro Hino, Kensuke Kayamori, Nagisa Oshima-Hasegawa, Shio Mitsukawa, Tomoya Muto, Naoya Mimura, Chiaki Nakaseko, Emiko Sakaida
Journal: Blood
Blood (2023) 142 (Supplement 1): 2204.
https://doi.org/10.1182/blood-2023-178437
Published: 2023
Journal Articles

Regulation of Metabolic Homeostasis By TRAF6 Contributes to the Leukemia Progression

Shinichiro Matsui, Chihiro Ri, Lyndsey C. Bolanos, Kwangmin Choi, Asuka Shibamiya, Arata Ishii, Koji Takaishi, Nagisa Oshima-Hasegawa, Shokichi Tsukamoto, Yusuke Takeda, Naoya Mimura, Koutaro Yokote, Daniel T. Starczynowski, Emiko Sakaida, Tomoya Muto
Journal: Blood
Blood (2023) 142 (Supplement 1): 1370.
https://doi.org/10.1182/blood-2023-178962
Published: 2023
Journal Articles

Exhausted T Cells Characterized By Upregulation of Specific Transcription Factors Are Increased in a Mouse Model of De Novo Mature B Cell Neoplasms

Asuka Shibamiya, Naoya Mimura, Yurie Miyamoto-Nagai, Shuhei Koide, Motohiko Oshima, Ola Rizq, Kazumasa Aoyama, Yaeko Nakajima-Takagi, Kensuke Kayamori, Yusuke Isshiki, Nagisa Oshima-Hasegawa, Tomoya Muto, Shokichi Tsukamoto, Yusuke Takeda, Ryo Koyama-Nasu, Tetsuhiro Chiba, Hiroaki Honda, Koutaro Yokote, Atsushi Iwama, Emiko Sakaida
Journal: Blood
Blood (2022) 140 (Supplement 1): 4240–4241.
https://doi.org/10.1182/blood-2022-158111
Published: 2022
Journal Articles

Detection of Clonal Plasma Cells in POEMS Syndrome Using Multiparameter Flow Cytometry

Arata Ishii, Shokichi Tsukamoto, Naoya Mimura, Yurie Nagai, Shinichiro Matsui, Sanshiro Nakao, Asuka Shibamiya, Yutaro Hino, Kensuke Kayamori, Nagisa Oshima-Hasegawa, Tomoya Muto, Shio Mitsukawa, Yusuke Takeda, Tomoki Suichi, Sonoko Misawa, Chikako Ohwada, Koutaro Yokote, Satoshi Kuwabara, Chiaki Nakaseko, Hiroyuki Takamatsu, Emiko Sakaida
Journal: Blood
Blood (2021) 138 (Supplement 1): 2697.
https://doi.org/10.1182/blood-2021-150900
Published: 2021
Journal Articles

Efficacy of Tubulin Polymerization Inhibitor in Myelodysplastic Syndrome

Cheng Zhong, Kensuke Kayamori, MD PhD, Shuhei Koide, Daisuke Shinoda, MD, Motohiko Oshima, PhD, Yaeko Nakajima-Takagi, PhD, Yurie Nagai, MD, Naoya Mimura, MD PhD, William Lennox, Josephine Sheedy, BS, MSc, Marla Weetall, PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-134754
Published: 2020
Journal Articles

Minimal Residual Disease in Autografts and Bone Marrow of Patients with Multiple Myeloma: 8-Color Multiparameter Flow Cytometry (EuroFlow-NGF) Vs . Next-Generation Sequencing

Hiroyuki Takamatsu, MDPhD, Naoki Takezako, MDPhD, Takeshi Yoroidaka, MD, Takeshi Yamashita, MD, Ryoichi Murata, MD, Atsuko Yamazaki, MD, Masahiro Takeuchi, MD PhD, Naoya Mimura, MD PhD, Chiaki Nakaseko, MD PhD, Emiko Sakaida, MDPhD, Masahiro Onoda, MD, Yoshikazu Utsu, MD PhD, Motoharu Fukazawa, MD, Kosei Matsue, MDPhD, Shinji Nakao, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-137014
Published: 2020
Journal Articles

Genomic Analysis of Diffuse Large B Cell Lymphoma in a Japanese Cohort Using Targeted DNA Sequencing

Tatsuzo Mishina, MD, Nagisa Oshima-Hasegawa, MD PhD, Shokichi Tsukamoto, MDPhD, Masaki Fukuyo, PhD, Hajime Kageyama, Bahityar Rahmutulla, MDPhD, Yurie Nagai, MD, Kensuke Kayamori, MD PhD, Yutaro Hino, MD PhD, Tomoya Muto, MD PhD, Shio Mitsukawa, MD PhD, Yusuke Takeda, MD PhD, Naoya Mimura, MD PhD, Chikako Ohwada, MD PhD, Masahiro Takeuchi, MD PhD, Hideki Tsujimura, MD PhD, Tohru Iseki, MDPhD, Chiaki Nakaseko, MDPhD, Jun-ichiro Ikeda, MD PhD, Makiko Itami, MD PhD, Koutaro Yokote, MD PhD, Osamu Ohara, PhD, Atsushi Kaneda, MDPhD, Emiko Sakaida, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2020-134891
Published: 2020
Journal Articles

Identification of Clonal Immunoglobulin λ Light-Chain Gene Rearrangements in AL Amyloidosis Using Next Generation Sequencing

Kenji Kimura, MD, Shokichi Tsukamoto, MD PhD, Kanji Miyazaki, MD PhD, Chika Kawajiri-Manako, MD PhD, Bahityar Rahmutulla, MD PhD, Masaki Fukuyo, PhD, Nagisa Oshima-Hasegawa, MD PhD, Shio Mitsukawa, MD PhD, Yusuke Takeda, MD PhD, Naoya Mimura, MD PhD, Masahiro Takeuchi, MD PhD, Chikako Ohwada, MD PhD, Tohru Iseki, MD PhD, Keisuke Matsusaka, MD PhD, Koutaro Yokote, MD PhD, Atsushi Kaneda, MD PhD, Tadao Ishida, MD PhD, Kenshi Suzuki, MD PhD, Chiaki Nakaseko, MD PhD, Emiko Sakaida, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1748.
https://doi.org/10.1182/blood-2019-125028
Published: 2019
Journal Articles

Akt Inhibition Differently Controls PRC2 Components and Synergizes with Dual EZH2/1 Inhibitor in the Treatment of Multiple Myeloma

Mohamed Rizk, BSc, MSc, Ola Rizq, MD PhD, Motohiko Oshima, PhD, Yaeko Nakajima-Takagi, PhD, Shuhei Koide, PhD, Atsunori Saraya, Yusuke Isshiki, MD PhD, Tetsuhiro Chiba, MD PhD, Satoshi Yamazaki, PhD, Anqi Ma, PhD, Jian Jin, PhD, Atsushi Iwama, MD PhD, Naoya Mimura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4400.
https://doi.org/10.1182/blood-2019-122157
Published: 2019
Journal Articles

The Preclinical Activities of PTC596, a Novel Tubulin Binding Agent That Down-Regulates BMI1, Alone and in Combination with Bortezomib in Multiple Myeloma

Yurie Nagai, MD, Naoya Mimura, MD PhD, Ola Rizq, MD PhD, Yusuke Isshiki, MD PhD, Motohiko Oshima, PhD, Mohamed Rizk, BSc, MSc, Atsunori Saraya, Shuhei Koide, PhD, Yaeko Nakajima-Takagi, PhD, Makiko Miyota, Nagisa Oshima-Hasegawa, MD PhD, Shokichi Tsukamoto, MD PhD, Shio Mitsukawa, MD PhD, Yusuke Takeda, MD PhD, Chikako Ohwada, MD PhD, Masahiro Takeuchi, MD PhD, Tohru Iseki, MD PhD, Chiaki Nakaseko, MD PhD, Josephine Sheedy, BS, MSc, Marla Weetall, PhD, Atsushi Iwama, MD PhD, Emiko Sakaida, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4414.
https://doi.org/10.1182/blood-2019-122350
Published: 2019
Journal Articles

Synergistic Effect of DHODH Inhibitor PTC299 with DNA Demethylating Agent Decitabine in Myelodysplastic Syndromes

Kensuke Kayamori, Cheng Zhong, Daisuke Shinoda, MD, Shuhei Koide, PhD, Motohiko Oshima, PhD, Yaeko Nakajima-Takagi, PhD, Naoya Mimura, MD PhD, Ryoji Ito, Kaoru Tohyama, MD PhD, William Lennox, Marla Weetall, PhD, Josephine Sheedy, BS, MSc, Emiko Sakaida, MD PhD, Koutaro Yokote, MD PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5407.
https://doi.org/10.1182/blood-2019-125200
Published: 2019
Journal Articles

Utx Insufficiency Cooperates with Braf V600E in the Induction of Myeloma in Mice

Ola Rizq, MD PhD, Naoya Mimura, MD PhD, Motohiko Oshima, PhD, Shuji Momose, MD PhD, Yaeko Nakajima-Takagi, PhD, Kazumasa Aoyama, PhD, Atsunori Saraya, Tohru Iseki, MD PhD, Emiko Sakaida, MD PhD, Chiaki Nakaseko, MDPhD, Yutaka Okuno, MD, PhD, Hiroaki Honda, MD PhD, Jun-ichi Tamaru, MDPhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1005.
https://doi.org/10.1182/blood-2018-99-114053
Published: 2018
Journal Articles

Anagrelide Inhibits Proliferation and Platelet Generation in Immortalized Megakaryocyte Progenitor Cell Lines Established from Human Induced Pluripotent Stem Cells

Koji Takaishi, MD, Masahiro Takeuchi, MD PhD, Shokichi Tsukamoto, MD PhD, Naoya Takayama, MD PhD, Motohiko Oshima, PhD, Yusuke Isshiki, MD, Kensuke Kayamori, MD, Kenji Kimura, MD, Yutaro Hino, MD, Nagisa Oshima-Hasegawa, MD PhD, Shio Mitsukawa, MD PhD, Yusuke Takeda, MD PhD, Naoya Mimura, MD PhD, Chikako Ohwada, MD PhD, Tohru Iseki, MD PhD, Sou Nakamura, PhD, Koji Eto, MD PhD, Atsushi Iwama, MD PhD, Koutaro Yokote, MD PhD, Chiaki Nakaseko, MDPhD, Emiko Sakaida, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1789.
https://doi.org/10.1182/blood-2018-99-111683
Published: 2018
Journal Articles

Long-term evaluation of physical improvement and survival of autologous stem cell transplantation in POEMS syndrome

Chikako Ohwada, Emiko Sakaida, Chika Kawajiri-Manako, Yuhei Nagao, Nagisa Oshima-Hasegawa, Emi Togasaki, Tomoya Muto, Shokichi Tsukamoto, Shio Mitsukawa, Yusuke Takeda, Naoya Mimura, Masahiro Takeuchi, Naomi Shimizu, Sonoko Misawa, Tohru Iseki, Satoshi Kuwabara, Chiaki Nakaseko
Journal: Blood
Blood (2018) 131 (19): 2173–2176.
https://doi.org/10.1182/blood-2017-07-795385
Published: 2018
Includes: Supplemental data
Journal Articles

Detection of MYD88 L265P Mutation By Next Generation Deep Sequencing in Peripheral Blood Mononuclear Cells of Waldenstrom Macroguloblinemia and IgM Monoclonal Gammopathy of Undetermined Significance

Ayako Nakamura, MD, Chikako Ohwada, MD PhD, Masahiro Takeuchi, MD PhD, Yusuke Takeda, MD PhD, Shokichi Tsukamoto, MDPhD, Naoya Mimura, MD PhD, Nagisa Oshima-Hasegawa, MD PhD, Yuhei Nagao, MD, Emi Togasaki, MD PhD, Hiroaki Tanaka, MD PhD, Chika Kawajiri-Manako, MD PhD, Yasumasa Sugita, MD PhD, Hisashi Wakita, MD PhD, Nobuyuki Aotsuka, MD PhD, Kosei Matsue, MD PhD, Kotaro Yokote, MD PhD, Osamu Ohara, MD PhD, Chiaki Nakaseko, MDPhD, Emiko Sakaida, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2744.
https://doi.org/10.1182/blood.V130.Suppl_1.2744.2744
Published: 2017
Journal Articles

p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma

Clinical Trials & Observations
Teru Hideshima, Francesca Cottini, Yoshihisa Nozawa, Hyuk-Soo Seo, Hiroto Ohguchi, Mehmet K. Samur, Diana Cirstea, Naoya Mimura, Yoshikazu Iwasawa, Paul G. Richardson, Nikhil C. Munshi, Dharminder Chauhan, Walter Massefski, Teruhiro Utsugi, Sirano Dhe-Paganon, Kenneth C. Anderson
Journal: Blood
Blood (2017) 129 (10): 1308–1319.
https://doi.org/10.1182/blood-2016-09-738500
Published: 2017
Includes: Supplemental data
Journal Articles

Molecular Mechanism behind the Synergistic Activity of Proteasome Inhibition and PRC2 Inhibition in the Treatment of Multiple Myeloma

Ola Rizq, MD, Naoya Mimura, MD PhD, Motohiko Oshima, PhD, Atsunori Saraya, Shuhei Koide, PhD, Yuko Kato, PhD, Kazumasa Aoyama, PhD, Yaeko Nakajima-Takagi, PhD, Changshan Wang, PhD, Anqi Ma, Jian Jin, PhD, Tohru Iseki, MD PhD, Chiaki Nakaseko, MD, PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2016) 128 (22): 312.
https://doi.org/10.1182/blood.V128.22.312.312
Published: 2016
Journal Articles

Distinctive Genetic Features of Plasma Cells in POEMS Syndrome

Yuhei Nagao, MD, Naoya Mimura, MD PhD, June Takeda, MD, Motohiko Oshima, PhD, Kenichi Yoshida, MD PhD, Yusuke Shiozawa, MD, Kazumasa Aoyama, PhD, Atsunori Saraya, Shuhei Koide, PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Hiroko Tanaka, BA, Chika Kawajiri-Manako, MD, Nagisa Hasegawa, MD, Shio Sakai, MD PhD, Yusuke Takeda, MD PhD, Chikako Ohwada, MD PhD, Masahiro Takeuchi, MD PhD, Emiko Sakaida, MD PhD, Tohru Iseki, MD PhD, Sonoko Misawa, MD PhD, Koutaro Yokote, MD PhD, Satoru Miyano, PhD, Osamu Ohara, PhD, Satoshi Kuwabara, MD PhD, Masashi Sanada, MD PhD, Atsushi Iwama, MD PhD, Seishi Ogawa, MD PhD, Chiaki Nakaseko, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4404.
https://doi.org/10.1182/blood.V128.22.4404.4404
Published: 2016
Journal Articles

Clonal Immunoglobulin λ Light-Chain Gene Rearrangements Detected By Next Generation Sequencing in POEMS Syndrome

Chika Kawajiri-Manako, MD, Naoya Mimura, MD PhD, Masaki Fukuyo, PhD, Hiroe Namba-Fukuyo, MS, Bahityar Rahmutulla, MD PhD, Yuhei Nagao, MD, Emi Togasaki, MD PhD, Ryoh Shimizu, MD PhD, Nagisa Hasegawa, MD, Shio Sakai, MD PhD, Yusuke Takeda, MD PhD, Chikako Ohwada, MD PhD, Masahiro Takeuchi, MD PhD, Emiko Sakaida, MD PhD, Tohru Iseki, MD PhD, Sonoko Misawa, MD PhD, Koutaro Yokote, MD PhD, Makoto Tsuiji, PhD, Satoshi Kuwabara, MD PhD, Atsushi Kaneda, MD PhD, Chiaki Nakaseko, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4405.
https://doi.org/10.1182/blood.V128.22.4405.4405
Published: 2016
Journal Articles

The KDM3A-KLF2-IRF4 Axis Maintains Myeloma Cell Survival

Hiroto Ohguchi, MD PhD, Teru Hideshima, MDPhD, Manoj Bhasin, PhD, Gullu Gorgun, PhD, Loredana Santo, MD, Michele Cea, MD, Naoya Mimura, MD PhD, Rikio Suzuki, MDPhD, Yu-Tzu Tai, PhD, Ruben D. Carrasco, MD PhD, Noopur S. Raje, MD, Paul G. Richardson, MD, Hideo Harigae, MD PhD, Takaomi Sanda, MD PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2015) 126 (23): 3633.
https://doi.org/10.1182/blood.V126.23.3633.3633
Published: 2015