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Journal Articles

Stapled BAD BH3 Helices Effectively Target BCL-2 Mutants That Cause Venetoclax Resistance

Thomas M. Deangelo, Utsarga Adhikary, Kyle J. Korshavn, Clara R. Brotzen-Smith, Hyuk-Soo Seo, Kijun Song, Luke Sebastian, Sirano Dhe-Paganon, Thomas E. Wales, Gregory H. Bird, Loren D. Walensky
Journal: Blood
Blood (2024) 144 (Supplement 1): 7472.
https://doi.org/10.1182/blood-2024-208553
Published: 2024
Journal Articles

Pharmacological Targeting of IRF4 As a Therapeutic Strategy for Multiple Myeloma

Michael P. Agius, Laura Hevenor, N Connor Payne, Qi Liu, Hyuk-Soo Seo, Romanos Sklavenitis-Pistofidis, Daniel Heilpern-Mallory, Puspalata Bashyal, Michelle P. Aranha, Elizabeth D. Lightbody, Ralph Mazitschek, Sirano Dhe-Paganon, Jun Qi, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 155.
https://doi.org/10.1182/blood-2024-203381
Published: 2024
Journal Articles

Discovery of First-in-Class Small Molecule Inhibitors of the IRF4-PU.1/Spi-B Interaction

Mike P. Agius, Laura Hevenor, N Connor Payne, Ralph Mazitschek, Hyuk-Soo Seo, Sirano Dhe-Paganon, Jun Qi, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 3635.
https://doi.org/10.1182/blood-2023-186864
Published: 2023
Journal Articles

p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma

Clinical Trials & Observations
Teru Hideshima, Francesca Cottini, Yoshihisa Nozawa, Hyuk-Soo Seo, Hiroto Ohguchi, Mehmet K. Samur, Diana Cirstea, Naoya Mimura, Yoshikazu Iwasawa, Paul G. Richardson, Nikhil C. Munshi, Dharminder Chauhan, Walter Massefski, Teruhiro Utsugi, Sirano Dhe-Paganon, Kenneth C. Anderson
Journal: Blood
Blood (2017) 129 (10): 1308–1319.
https://doi.org/10.1182/blood-2016-09-738500
Published: 2017
Includes: Supplemental data