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Jeffrey Ecsedy
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Journal Articles

The Investigational Aurora A Kinase Inhibitor MLN8237 in Combination with Vincristine Demonstrates Robust Anti-Tumor Activity in Preclinical B-Cell Non-Hodgkin's Lymphoma Models

Mengkun Zhang, Jessica Huck, Marc Hyer, Karuppian Kannan, Wen Chyi Shyu, Susan Chen, Mark Manfredi, Jeffrey Ecsedy
Journal: Blood
Blood (2011) 118 (21): 2733.
https://doi.org/10.1182/blood.V118.21.2733.2733
Published: 2011
Journal Articles

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

Güllü Görgün, Elisabetta Calabrese, Teru Hideshima, Jeffrey Ecsedy, Giulia Perrone, Mala Mani, Hiroshi Ikeda, Giada Bianchi, Yiguo Hu, Diana Cirstea, Loredana Santo, Yu-Tzu Tai, Sabikun Nahar, Mei Zheng, Madhavi Bandi, Ruben D. Carrasco, Noopur Raje, Nikhil Munshi, Paul Richardson, Kenneth C. Anderson
Journal: Blood
Blood (2010) 115 (25): 5202–5213.
https://doi.org/10.1182/blood-2009-12-259523
Published: 2010
Includes: Supplemental data
Journal Articles

A NOVEL Aurora A Kinase INHIBITOR MLN8237 Induces Cytotoxicity and CELL Cycle Arrest IN MULTIPLE MYELOMA.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Teru Hideshima, MD, PhD, Jeffrey Ecsedy, PhD, Giada Bianchi, MD, Mala Mani, PhD, Madhavi Bandi, Hiroshi Ikeda, MD, PhD, Giulia Perrone, MD, Yiguo Hu, MD, PhD, Yu-Tzu Tai, PhD, Mei Zheng, Diana Cristea, MD, Loredana Santo, MD, Daniel R. Carrasco, MD, PhD, Nikhil Munshi, MD, Paul Richardson, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2009) 114 (22): 3830.
https://doi.org/10.1182/blood.V114.22.3830.3830
Published: 2009
Journal Articles

The Novel Orally Active Aurora A Kinase Inhibitor MLN8237 Is Highly Active in Preclinical Models of Acute Myeloid Leukemia and Significantly Increases the Efficacy of Cytarabine.

Kevin R. Kelly, MD, Ronan T. Swords, M.D., Devalingam Mahalingam, M.D., Steffan T. Nawrocki, PhD, Ernest Medina, B.S., Sabrina Smith, Swaminathan Padmanabhan, MD, MBBS, Jeffrey Ecsedy, Mary R Cahill, FRCPI, FRCPath, Francis J. Giles, MB, MD, FRCPI, FRCPath, Jennifer S. Carew, Ph.D.
Journal: Blood
Blood (2009) 114 (22): 2087.
https://doi.org/10.1182/blood.V114.22.2087.2087
Published: 2009
Journal Articles

A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Mala Mani, PhD, Teru Hideshima, M.D., Ph.D., Hiroshi Ikeda, MD, PhD, Giulia Perrone, MD, Loredana Santo, MD, Diana Cirstea, MD, Simona Blotta, Paul G. Richardson, MD, Jeffrey Ecsedy, Kenneth C. Anderson, MD
Journal: Blood
Blood (2008) 112 (11): 1719.
https://doi.org/10.1182/blood.V112.11.1719.1719
Published: 2008
Journal Articles

The Aurora Kinase Inhibitor MLN8237 Has Potent Anticancer Activity in CML and Ph+ ALL Models and Significantly Increases the Efficacy of Nilotinib

Steffan T. Nawrocki, Ph.D., Ernest Medina, B.S., Sabrina Smith, B.S., Ronan Swords, M.D., Kevin Kelly, M.D., Swaminathan Padmanabhan, M.D., Jeffrey Ecsedy, Ph.D., Francis J Giles, M.D., Jennifer Carew, Ph.D.
Journal: Blood
Blood (2008) 112 (11): 3198.
https://doi.org/10.1182/blood.V112.11.3198.3198
Published: 2008