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Journal Articles

Bone Marrow Niche Down-Regulates Mir-30 In Multiple Myeloma Cells to Promote Cancer Progression and Cancer Initiation by Targeting BCL9/Wnt Pathway.

Jian-Jun Zhao, M.D., Ph.D., Jianhong Lin, M.D., Zhangbo Chu, M.D., Qi Wang, Ph.D., Kohichi Takada, M.D., Ph.D., Mala Mani, Ph.D., Bryan Ciccarelli, Teru Hideshima, M.D., Ph.D., Tai Yu-Tzu, Ph.D., Jianguo Tao, MD, PhD, Steven P. Treon, MD, PhD, Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D., Ruben Carrasco, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1569.
https://doi.org/10.1182/blood.V116.21.1569.1569
Published: 2010
Journal Articles

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

Güllü Görgün, Elisabetta Calabrese, Teru Hideshima, Jeffrey Ecsedy, Giulia Perrone, Mala Mani, Hiroshi Ikeda, Giada Bianchi, Yiguo Hu, Diana Cirstea, Loredana Santo, Yu-Tzu Tai, Sabikun Nahar, Mei Zheng, Madhavi Bandi, Ruben D. Carrasco, Noopur Raje, Nikhil Munshi, Paul Richardson, Kenneth C. Anderson
Journal: Blood
Blood (2010) 115 (25): 5202–5213.
https://doi.org/10.1182/blood-2009-12-259523
Published: 2010
Includes: Supplemental data
Journal Articles

RFP2 Modulates 20S Proteasome Activity, NF Kappa B Activation, and Tumor Cell Growth in Multiple Myeloma.

Moshe E Gatt, MD, Mala Mani, PhD, Mikael Lerner, Teru Hideshima, M.D., Ph.D., Yunyu Zhang, Jui Dutta, Daniel E Carrasco, Alexei Protopopov, Olle Sangfelt, Dan Grander, MD, PhD, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., Kenneth C. Anderson, MD, Daniel Ruben Carrasco, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 1786.
https://doi.org/10.1182/blood.V114.22.1786.1786
Published: 2009
Journal Articles

A NOVEL Aurora A Kinase INHIBITOR MLN8237 Induces Cytotoxicity and CELL Cycle Arrest IN MULTIPLE MYELOMA.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Teru Hideshima, MD, PhD, Jeffrey Ecsedy, PhD, Giada Bianchi, MD, Mala Mani, PhD, Madhavi Bandi, Hiroshi Ikeda, MD, PhD, Giulia Perrone, MD, Yiguo Hu, MD, PhD, Yu-Tzu Tai, PhD, Mei Zheng, Diana Cristea, MD, Loredana Santo, MD, Daniel R. Carrasco, MD, PhD, Nikhil Munshi, MD, Paul Richardson, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2009) 114 (22): 3830.
https://doi.org/10.1182/blood.V114.22.3830.3830
Published: 2009
Journal Articles

Immunomodulatory EFFECTS of Lenalidomide and Pomalidomide ON INTERACTION of TUMOR and BONE MARROW Accessory CELLS IN MULTIPLE MYELOMA.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Teru Hideshima, MD, PhD, Giulia Perrone, MD, Giada Bianchi, MD, Hiroshi Ikeda, MD, PhD, Mala Mani, PhD, Yiguo Hu, MD, PhD, Diana Cristea, MD, Loredana Santo, MD, Yu-Tzu Tai, PhD, Nikhil Munshi, MD, Paul Richardson, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2009) 114 (22): 950.
https://doi.org/10.1182/blood.V114.22.950.950
Published: 2009
Journal Articles

The Functional Role of Microrna 15a/16-1 as Tumor Suppressor Genes in Multiple Myeloma.

Moshe E Gatt, MD, Margaret Ebert, Mala Mani, PhD, Yunyu Zhang, Roi Gazit, PhD, Daniel E Carrasco, Jui Dutta, Sophia Adamia, Nikhil C. Munshi, Stéphane Minvielle, Herve Avet-Loiseau, MD, PhD, Yu-Tzu Tai, Ph.D., Kenneth C. Anderson, MD, Daniel Ruben Carrasco, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 1963.
https://doi.org/10.1182/blood.V114.22.1963.1963
Published: 2009
Journal Articles

Aurora kinase A is a target of Wnt/β-catenin involved in multiple myeloma disease progression

Jui Dutta-Simmons, Yunyu Zhang, Gullu Gorgun, Moshe Gatt, Mala Mani, Teru Hideshima, Kohichi Takada, Nicole E. Carlson, Daniel E. Carrasco, Yu-Tzu Tai, Noopur Raje, Anthony G. Letai, Kenneth C. Anderson, Daniel R. Carrasco
Journal: Blood
Blood (2009) 114 (13): 2699–2708.
https://doi.org/10.1182/blood-2008-12-194290
Published: 2009
Includes: Supplemental data
Journal Articles

The BCL9 Oncogene Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic and Angiogenic Properties to Myeloma Cells

Mala Mani, Ph.D., Jui Dutta, Yunyu Zhang, Daniel E Carrasco, Yiming Zhou, Moshe Gatt, Bart Barlogie, John D. Shaughnessy, Jr., PhD, Kenneth C Anderson, MD, Daniel Ruben Carrasco, M.D., Ph.D.
Journal: Blood
Blood (2008) 112 (11): 648.
https://doi.org/10.1182/blood.V112.11.648.648
Published: 2008
Journal Articles

A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Mala Mani, PhD, Teru Hideshima, M.D., Ph.D., Hiroshi Ikeda, MD, PhD, Giulia Perrone, MD, Loredana Santo, MD, Diana Cirstea, MD, Simona Blotta, Paul G. Richardson, MD, Jeffrey Ecsedy, Kenneth C. Anderson, MD
Journal: Blood
Blood (2008) 112 (11): 1719.
https://doi.org/10.1182/blood.V112.11.1719.1719
Published: 2008
Journal Articles

RFP2 Knockdown Disrupts Cell Growth and Induces Apoptosis in Multiple Myeloma

Moshe E. Gatt, MD, Mala Mani, PhD, Jui Dutta, PhD, Daniel E. Carrasco, John D Shaughnessy, Jr., PhD, Kenneth C. Anderson, MD, Daniel R Carrasco, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 5327.
https://doi.org/10.1182/blood.V112.11.5327.5327
Published: 2008
Journal Articles

Preclinical Validation of a Clinical Grade Novel Specific Small Molecule Cyclin D1 Inhibitor, P276-00 for the Treatment of Multiple Myeloma.

Noopur Raje, MD, Teru Hideshima, MD, Sonia Vallet, MD, Diana Cirstea, MD, Tanyel Kiziltepe, PhD, Shweta Chhetri, Mala Mani, Siddhartha Mukherjee, MD, Daniel Ruben Carrasco, MD, Constantine Mitsiades, MD, Melissa Rooney, Klaus Podar, MD, PhD, Yutaka Okawa, MD, Hiroshi Ikeda, MD, Paul G. Richardson, MD, Dharminder Chauhan, PhD, Nikhil C. Munshi, MD, Somesh Sharma, PhD, Himanshu Parikh, MD, Bruce Chabner, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2007) 110 (11): 256.
https://doi.org/10.1182/blood.V110.11.256.256
Published: 2007