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Frank Osterroth
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Journal Articles

BT062, an Antibody-Drug Conjugate Directed Against CD138, Given Weekly for 3 Weeks in Each 4 Week Cycle: Safety and Further Evidence of Clinical Activity

Leonard T Heffner, MD, Sundar Jagannath, MD, Todd M Zimmerman, MD, Kelvin P Lee, MD, Jacalyn Rosenblatt, MD, Sagar Lonial, MD, Robert J. Lutz, PhD, Niklas Czeloth, PhD, Frank Osterroth, PhD, Markus Ruehle, MD, Michelle A. Beelitz, Andrea Wartenberg-Demand, MD, Thomas Haeder, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2012) 120 (21): 4042.
https://doi.org/10.1182/blood.V120.21.4042.4042
Published: 2012
Journal Articles

BT062, An Antibody-Drug Conjugate Directed Against CD138, Shows Clinical Activity in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma

Sundar Jagannath, MD, Asher Chanan-Khan, MD, Leonard T. Heffner, MD, David Avigan, MD, Todd M. Zimmerman, MD, Sagar Lonial, MD, Robert J. Lutz, PhD, Andre Engling, PhD, Christoph Uherek, PhD, Frank Osterroth, PhD, Markus Ruehle, MD, Michelle A. Beelitz, Gabriele Niemann, PhD, Andrea Wartenberg-Demand, MD, Thomas Haeder, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2011) 118 (21): 305.
https://doi.org/10.1182/blood.V118.21.305.305
Published: 2011
Journal Articles

BT062, a CD138-Specific Immunoconjugate, Demonstrates Superior In Vivo Anti-Myeloma Efficacy In Combination with Lenalidomide or Bortezomib

Chantal Zuber, PhD, Benjamin Daelken, PhD, Silke Aigner, PhD, Thomas Haeder, PhD, Olga Ab, PhD, Kathleen Whiteman, PhD, Teru Hideshima, Robert J Lutz, PhD, Frank Osterroth, PhD, Christoph Uherek, PhD
Journal: Blood
Blood (2010) 116 (21): 3008.
https://doi.org/10.1182/blood.V116.21.3008.3008
Published: 2010
Journal Articles

BT062, An Antibody-Drug Conjugate Directed Against CD138, Shows Clinical Activity In a Phase I Study In Patients with Relapsed or Relapsed/Refractory Multiple Myeloma

Sundar Jagannath, MD, Asher A. Chanan-Khan, MD, Leonard T Heffner, MD, David Avigan, MD, Robert J Lutz, PhD, Christoph Uherek, PhD, Frank Osterroth, PhD, Markus Ruehle, MD, Thomas Haeder, PhD, Gabriele Niemann, PhD, Andrea Wartenberg-Demand, MD, Nikhil C. Munshi, MD, Kenneth C. Anderson
Journal: Blood
Blood (2010) 116 (21): 3060.
https://doi.org/10.1182/blood.V116.21.3060.3060
Published: 2010
Journal Articles

The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Potent and Selective Cytotoxicity against CD138 Positive Multiple Myeloma Cells in Vitro and in Vivo.

Hiroshi Ikeda, MD, PhD, Teru Hideshima, MD, PhD, Robert J. Lutz, Sonia Vallet, Samantha Pozzi, MD, Loredana Santo, Elisabetta Calabrese, Benjamin Dälken, Christoph Uherek, Silke Aigner, Frank Osterroth, Mariateresa Fultiniti, Yutaka Okawa, Giulia Perrone, Gullu Gorgun, Hiroshi Yasui, Diana Cristia, Noopur Raje, MD, Nikhil Munshi, MD, Paul Richardson, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2008) 112 (11): 1716.
https://doi.org/10.1182/blood.V112.11.1716.1716
Published: 2008
Journal Articles

Stimulation of cytotoxic T cells against idiotype immunoglobulin of malignant lymphoma with protein-pulsed or idiotype-transduced dendritic cells

Frank Osterroth, Annette Garbe, Paul Fisch, Hendrik Veelken
Journal: Blood
Blood (2000) 95 (4): 1342–1349.
https://doi.org/10.1182/blood.V95.4.1342.004k19_1342_1349
Published: 2000