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Journal Articles

Preliminary results from RIVER-81, a phase 2 study of romaciclib (RVU120) + venetoclax in patients with acute myeloid leukemia failing first-line venetoclax + hypomethylating agent (HMA)

Free
Pau Montesinos, Adolfo De La Fuente Burguera, Sara Garcia Avila, Thomas Cluzeau, Sylvain Garciaz, Krzysztof Madry, Witold Prejzner, Milena Mazan, Urszula Pakulska, Urszula Glowniak, Jan Kulis, Diego Coelho, Marta Obacz, Agnieszka Sroka-Porada, Gary Wilkinson, Renata Windak, Renata Dudziak, Chadi Saba, Tomasz Rzymski, Hendrik Nogai, Cristina Papayannidis, Giovanni Marconi, Jaroslaw Dybko, Juan Miguel Bergua Burgues, Maria Benedetta Giannini, Ernesta Audisio
Journal: Blood
Blood (2025) 146 (Supplement 1): 3424.
https://doi.org/10.1182/blood-2025-3424
Published: 2025
Journal Articles

NPM1 and IDH1/2 mutations show limited prognostic impact in relapsed AML: Evidence from the avalon cohort

Free
Calogero Vetro, Irene Azzali, Elisabetta Petracci, Cristina Papayannidis, Eleonora Eleuteri, Fanny Erika Palumbo, Vincenzo Federico, Nicola Stefano Fracchiolla, Patrizia Zappasodi, Maria Paola Martelli, Maria Benedetta Giannini, Lorenzo Brunetti, Raffaele Palmieri, jacopo nanni, Giorgia Simonetti, Fabio Guolo, Paola Minetto, Luca Maurillo, Federica Gigli, Atto Billio, Elisabetta Todisco, Giovanni Martinelli, Giovanni Marconi
Journal: Blood
Blood (2025) 146 (Supplement 1): 6967.
https://doi.org/10.1182/blood-2025-6967
Published: 2025
Journal Articles

Unveiling FLT3 in B-ALL: Molecular drivers and targeted treatment opportunities

Free
Anna Ferrari, Federico Lo Schiavo, Chiara Salvesi, Lorenzo Ledda, Matteo Paganelli, Asia Spedaluzzi, Cristina Papayannidis, Giovanni Marconi, Michela Rondoni, Anna Maria Mianulli, Barbara Giannini, Crescenza Pasciolla, Fabio Giglio, Sara Galimberti, Monica Fumagalli, Prassede Salutari, Valentina Gaidano, Eugenio Fonzi, Maria Benedetta Giannini, Andrea Ghelli Luserna di Rorà, Giovanni Martinelli, Giorgia Simonetti
Journal: Blood
Blood (2025) 146 (Supplement 1): 5148.
https://doi.org/10.1182/blood-2025-5148
Published: 2025
Journal Articles

Efficacy and safety of pivekimab sunirine in combination with venetoclax plus azacitidine in unfit patients with newly diagnosed Acute Myeloid Leukemia

Free
Naval Daver, Anjali Advani, Adolfo De La Fuente Burguera, Pau Montesinos, Sylvain Garciaz, Maria Benedetta Giannini, Eunice Wang, Gail Roboz, Antonio Curti, Monia Lunghi, Jessica Altman, Roland Walter, Patrick Burke, Kebede Begna, Daniel Deangelo, Uwe Platzbecker, Paresh Vyas, Christoph Schliemann, Kendra Sweet, Caroline Wagstaff, Naveen Pemmaraju, Hagop Kantarjian, Yining Du, Jalaja Potluri, David Sallman
Journal: Blood
Blood (2025) 146 (Supplement 1): 651.
https://doi.org/10.1182/blood-2025-651
Published: 2025
Journal Articles

Disease Course and Treatment Patterns of Acute Myeloid Leukemia with FLT3 Mutations and Myeloid Sarcoma Reveal High Efficacy of Gilteritinib: A Multicentric Retrospective Study

Free
Francesco Angotzi, Erika Borlenghi, Chiara Sartor, Maria Benedetta Giannini, Giovanni Marconi, Edoardo Tamellini, Mauro Turrini, Federica Loscocco, Ernesta Audisio, Vincenzo Federico, Calogero Vetro, Andrea Visentin, Carmela Gurrieri, Livio Trentin, Felicetto Ferrara, Federica Lessi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1523.
https://doi.org/10.1182/blood-2024-209605
Published: 2024
Journal Articles

River-81: A Multicenter, Open-Label, Dose-Finding Clinical Trial to Assess Safety, PK, PD, Clinical Efficacy of RVU120 in Combination with Venetoclax in Patients with AML Failing Prior Venetoclax Plus Hypomethylating Agent Therapy

Free
Maria Benedetta Giannini, Adolfo De la Fuente Burguera, Adriano Venditti, Witold Prejzner, Sara García, Noemi Angelosanto, Hendrik Nogai, Renata Dudziak, Vakul Mohanty, Natalia Baran, Marta Obacz, Urszula Pakulska, Jerzy Woźnicki, Katarzyna Wiklik, Marta Micek, Tomasz Rzymski, Milena Mazan, Agnieszka Sroka-Porada, Gary Wilkinson, Aleksandra Butrym, Erika Borlenghi, Krzysztof Mądry, Jan Kulis, Diego Coelho, Daniel Grzywczak
Journal: Blood
Blood (2024) 144 (Supplement 1): 5999.
https://doi.org/10.1182/blood-2024-200055
Published: 2024
Journal Articles

Pre-Existing Myeloid Subclones May Account for a Subset of Acute Myeloid Leukemias and Myelodysplastic Neoplasms in Patients with Pre-Existing or Contemporary Lymphoid Disorders

Free
Agnese Mattei, Giovanni Marconi, Sonia Ronconi, Delia Cangini, Michela Ceccolini, Claudio Cerchione, Irene Zacheo, Maria Benedetta Giannini, Marianna Norata, Giovanni Martinelli, Anna Ferrari, Maria Teresa Bochicchio, Martina Ghetti, Matteo Marchesini, Giorgia Simonetti, Gerardo Musuraca, Davide Nappi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1475.
https://doi.org/10.1182/blood-2023-186760
Published: 2023
Journal Articles

Impact of Comorbidities on Prognosis of Elderly Patients with Acute Myeloid Leukemia Who Receive Hypomethylating Agents

Free
Giovanni Marconi, Anna Candoni, Roberta di Nicola, Chiara Sartor, Sarah Parisi, Mariachiara Abbenante, Jacopo Nanni, Gianluca Cristiano, Davide Lazzarotto, Maria Benedetta Giannini, Carmen Baldazzi, Maria Chiara Fontana, Lorenza Bandini, Emanuela Ottaviani, Nicoletta Testoni, Chiara Di Giovanni Bezzi, Rania Abd-alatif, Renato Fanin, Giovanni Martinelli, Stefania Paolini, Michele Cavo, Cristina Papayannidis, Antonio Curti
Journal: Blood
Blood (2021) 138 (Supplement 1): 3373.
https://doi.org/10.1182/blood-2021-149459
Published: 2021
Journal Articles

Italian Observational Study on Real-Life Use of Venetoclax in Acute Myeloid Leukemia (AVALON study): Results of Interim Analysis on Relapsed/Refractory Patients

Free
Elisabetta Todisco, MDPhD, Nicola Fracchiolla, MD, Cristina Papayannidis, MD PhD, Maria Paola Martelli, MDPhD, Giuliana Rizzuto, Alessandro Cignetti, MD PhD, Nicola Di Renzo, MD, Patrizia Zappasodi, MD, Michele Gottardi, MD, Ernesta Audisio, MD, Monia Lunghi, MD, Federica Gigli, MD, Corrado Tarella, Chiara Zingaretti, Elisabetta Petracci, Roberta Volpi, Delia Cangini, Maria Benedetta Giannini, MD, Mariarita Sciumè, MD, Giuseppe Rossi, MD, Avalon Group, Giovanni Martinelli, MD, Claudio Cerchione, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-143082
Published: 2020
Journal Articles

Azacitidine and Lenalidomide in Higher-Risk Myelodysplastic Syndromes. Long-Term Results of a Randomized Phase II Multicenter Study and Impact of Cytogenetic Scores and Mutational Status on Long-Lasting Responses

Free
Carlo Finelli, Sarah Parisi, MDPhD, Matilde Y Follo, PhD, Cristina Clissa, MD, Miriam Fogli, PhD, Sara Mongiorgi, PhD, Costanza Bosi, MD, Isabella Capodanno, MD, Barbara Castagnari, MD, Anna Candoni, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Giovanna Leonardi, Maurizio Miglino, PhD, Gian Matteo Rigolin, Domenico Russo, MD, Patrizia Tosi, Andrea Pellagatti, Jacqueline Boultwood, Lucio Cocco, MD, Michele Cavo
Journal: Blood
Blood (2020) 136 (Supplement 1): 45.
https://doi.org/10.1182/blood-2020-138371
Published: 2020
Journal Articles

Pomalidomide-Dexamethasone in the Management of Heavily Pretreated Multiple Myeloma

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Claudio Cerchione, MD PhD, Lucio Catalano, Davide Nappi, Anna Emanuele Pareto, Gerardo Musuraca, MD, Alessandro Lucchesi, MD, Sonia Ronconi, Michela Ceccolini, MD, Delia Cangini, Maria Benedetta Giannini, MD, Valeria Di Battista, Giorgia Simonetti, PhD, Andrea Ghelli Luserna Di Rorà, PhD, Fabrizio Pane, Giovanni Martinelli, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-143143
Published: 2020
Journal Articles

A Preliminary Analysis of FLAM (Italian Non-Interventional Multi-center Study of FLT3 mutated AML patients): FLT3 Receptor Gene Mutational Analysis and FLT3 Inhibitors Administration in the Real-Life Clinical Practice

Free
Jacopo Nanni, MD, Ernesta Audisio, MD, Maria Benedetta Giannini, MD, Barbara MD Scappini, Benedetta Cambò, MD, Francesco Albano, Maria Paola Martelli, MDPhD, Alessandro Cignetti, MD PhD, Gian Matteo Rigolin, Nicola Fracchiolla, MD, Monica Bocchia, Claudio Romani, Elisabetta Todisco, MDPhD, Monia Lunghi, MD PhD, Anna Maria Mianulli, MD, Daniela Cilloni, MD PhD, Elisabetta Petracci, Irene Valli, Chiara Zingaretti, Claudio Cerchione, MD PhD, Delia Cangini, the FLAM collaborative Group, Cristina Papayannidis, MD PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–34.
https://doi.org/10.1182/blood-2020-139981
Published: 2020
Journal Articles

Comparison of Two Different Therapeutic Regimens with Azacitidine and Lenalidomide (Combined versus Sequential) in Higher-Risk Myelodysplastic Syndromes. Update of Long-Term Results of a Randomized Phase II Multicenter Study

Free
Carlo Finelli, MD, Cristina Clissa, MD, Matilde Y Follo, PhD, Sarah Parisi, Miriam Fogli, PhD, Sara Mongiorgi, PhD, Isabella Capodanno, Costanza Bosi, MD, Barbara Castagnari, MD, Anna Candoni, MD, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Marco Gobbi, MD, Giovanna Leonardi, Gian Matteo Rigolin, Domenico Russo, MD, Patrizia Tosi, MD, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Lucio Cocco, MD, Michele Cavo, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4365.
https://doi.org/10.1182/blood-2018-99-117714
Published: 2018
Journal Articles

Azacitidine and Lenalidomide (Combined vs Sequential Treatment) in Higher-Risk Myelodysplastic Syndromes. Long-Term Results of a Randomized Phase II Multicenter Study

Free
Carlo Finelli, MD, Cristina Clissa, MD, Matilde Follo, PhD, Marta Stanzani, MD, Sarah Parisi, MD, Sara Mongiorgi, PhD, Marilena Barraco, PhD, Paolo Avanzini, MD, Costanza Bosi, MD, Barbara Castagnari, MD, Anna Candoni, MD, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Marco Gobbi, MD, Giovanna Leonardi, Gian Matteo Rigolin, Domenico Russo, MD, Patrizia Tosi, Giuseppe Visani, MD, Lucio Cocco, MD, PhD, Michele Cavo, MD
Journal: Blood
Blood (2016) 128 (22): 3169.
https://doi.org/10.1182/blood.V128.22.3169.3169
Published: 2016
Journal Articles

Association of Azacitidine and Lenalidomide (Combined vs Sequential Treatment) in High-Risk Myelodysplastic Syndromes. Final Results of a Randomized Phase II Multicenter Study

Free
Carlo Finelli, MD, Cristina Clissa, MD, Matilde Follo, PhD, Marta Stanzani, MD, Sarah Parisi, MD, Sara Mongiorgi, PhD, Paolo Avanzini, MD, Costanza Bosi, MD, Barbara Castagnari, MD, Anna Candoni, MD, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Marco Gobbi, MD, Giovanna Leonardi, Gian Matteo Rigolin, Domenico Russo, Patrizia Tosi, Giuseppe Visani, MD, Lucio Cocco, MD, PhD, Michele Cavo
Journal: Blood
Blood (2015) 126 (23): 2871.
https://doi.org/10.1182/blood.V126.23.2871.2871
Published: 2015
Journal Articles

Addition of Lenalidomide (LEN) to Azacitidine (AZA) (Combined vs Sequential Treatment) in High-Risk Myelodysplastic Syndromes (MDS): A Randomized Phase II Multicenter Study

Free
Carlo Finelli, MD, Cristina Clissa, MD, Matilde Y Follo, PhD, Marta Stanzani, MD PhD, Paolo Avanzini, Costanza Bosi, MD, Barbara Castagnari, MD, Anna Candoni, MD, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Marco Gobbi, MD, Giovanna Leonardi, MD, Gian Matteo Rigolin, MD, Patrizia Tosi, MD, Giuseppe Visani, MD, Lucio Cocco, MD, Michele Cavo, MD, Domenico Russo, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4648.
https://doi.org/10.1182/blood.V124.21.4648.4648
Published: 2014
Journal Articles

Patologic IL 17 Producing Helper T Cells In Acute Myeloid Leukemia Patients

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Gerardo Musuraca, MD, PhD, Serena De Matteis, Roberta Napolitano, Francesco Fabbri, Delia Cangini, MD, Michela Ceccolini, MD, Maria Benedetta Giannini, MD, Alessandro Lucchesi, MD, Sonia Ronconi, MD, Cristina Papayannidis, MD, Viviana Guadagnuolo, Giovanni Martinelli, MD, Paolo Savini, MD, Monica Tani, MD, Patrizia Tosi, MD, Dino Amadori, MD, Pier Paolo Fattori, MD, Wainer Zoli, Silvia Carloni
Journal: Blood
Blood (2013) 122 (21): 2289.
https://doi.org/10.1182/blood.V122.21.2289.2289
Published: 2013
Journal Articles

Azacitidine in Myelodysplastic Syndromes: Multicenter Retrospective Study of 34 Long-Responder Patients

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Carlo Finelli, M.D., Cristina Clissa, M.D., Maria Teresa Voso, Maria Antonietta Aloe Spiriti, Massimo Breccia, Gianluca Gaidano, MD, PhD, Monica Crugnola, M.D., Maria Benedetta Giannini, M.D., Costanza Bosi, MD, Virginia Naso, MD, Matilde Y Follo, PhD, Sara Mongiorgi, PhD, Giovanni Martinelli, Lucio Cocco, MD, Michele Baccarani, MD
Journal: Blood
Blood (2012) 120 (21): 4951.
https://doi.org/10.1182/blood.V120.21.4951.4951
Published: 2012
Journal Articles

Long-Term Evaluation of 205 Patients with Essential Thrombocythemia: Clinical Outcome, Efficacy and Safety with Respect to Different Therapies.

Free
Nicola Vianelli, MD, Antonio deVivo, MD, Mauro Fiacchini, MD, Alessandro Lucchesi, MD, Benedetta Giannini, MD, Michele Baccarani, MD
Journal: Blood
Blood (2005) 106 (11): 4941.
https://doi.org/10.1182/blood.V106.11.4941.4941
Published: 2005
Journal Articles

Imatinib Therapy for Chronic Myeloid Leukemia Patients Who Relapse after Allogeneic Stem Cell Transplantation: A Molecular Analysis.

Free
Francesca Palandri, Giovanni Martinelli, Marilina Amabile, Francesca Bonifazi, Giuseppe Bandini, Fabio Benedetti, Emilio Usala, Emanuele Angelucci, Mario Tiribelli, Renato Fanin, Marco Sorio, Mario Arpinati, Nicoletta Testoni, Sadia Falcioni, Maria Benedetta Giannini, Angela Poerio, Simona Soverini, Fabrizio Pane, Gianantonio Rosti, Sante Tura, Michele Baccarani
Journal: Blood
Blood (2004) 104 (11): 4655.
https://doi.org/10.1182/blood.V104.11.4655.4655
Published: 2004