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Issue Archive

Volume 133, Issue 5
January 31 2019
Issue Cover

Table of Contents

EDITORIAL

Introduction to a review series on new therapeutics for inherited and acquired bleeding conditions
Thomas L. Ortel
View Articletitled, Introduction to a review series on new therapeutics for inherited and acquired bleeding conditions

BLOOD COMMENTARIES

THROMBOSIS AND HEMOSTASIS
Contact system sends defensins to the rescue
Laura D. Healy,Owen J. T. McCarty
View Articletitled, Contact system sends defensins to the rescue
CLINICAL TRIALS AND OBSERVATIONS
Highs and lows of minimal residual disease in CLL
Clinical Trials & Observations
Deborah M. Stephens
View Articletitled, Highs and lows of minimal residual disease in CLL

REVIEW SERIES

New therapies for hemophilia
Clinical Trials & Observations
Angela C. Weyand,Steven W. Pipe
View Articletitled, New therapies for hemophilia
New therapies using nonfactor products for patients with hemophilia and inhibitors
Clinical Trials & Observations
Keiji Nogami,Midori Shima
View Articletitled, New therapies using nonfactor products for patients with hemophilia and inhibitors
Update on clinical gene therapy for hemophilia
Clinical Trials & Observations
George Q. Perrin,Roland W. Herzog,David M. Markusic
View Articletitled, Update on clinical gene therapy for hemophilia
Treatment of rare factor deficiencies other than hemophilia
Clinical Trials & Observations
Marzia Menegatti,Flora Peyvandi
View Articletitled, Treatment of rare factor deficiencies other than hemophilia
Treatment of bleeding complications in patients on anticoagulant therapy
Clinical Trials & Observations
Siavash Piran,Sam Schulman
View Articletitled, Treatment of bleeding complications in patients on anticoagulant therapy

LYMPHOID NEOPLASIA

Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma
Clinical Trials & Observations
Christian Grommes,Sarah S. Tang,Julia Wolfe,Thomas J. Kaley,Mariza Daras,Elena I. Pentsova,Anna F. Piotrowski,Jacqueline Stone,Andrew Lin,Craig P. Nolan,Malbora Manne,Paolo Codega,Carl Campos,Agnes Viale,Alissa A. Thomas,Michael F. Berger,Vaios Hatzoglou,Anne S. Reiner,Katherine S. Panageas,Lisa M. DeAngelis,Ingo K. Mellinghoff
View Articletitled, Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma
Supplemental data

MYELOID NEOPLASIA

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment
Amina M. Abdul-Aziz,Yu Sun,Charlotte Hellmich,Christopher R. Marlein,Jayna Mistry,Eoghan Forde,Rachel E. Piddock,Manar S. Shafat,Adam Morfakis,Tarang Mehta,Federica Di Palma,Iain Macaulay,Christopher J. Ingham,Anna Haestier,Angela Collins,Judith Campisi,Kristian M. Bowles,Stuart A. Rushworth
View Articletitled, Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Single-cell analyses demonstrate that a heme–GATA1 feedback loop regulates red cell differentiation
Raymond T. Doty,Xiaowei Yan,Christopher Lausted,Adam D. Munday,Zhantao Yang,Danielle Yi,Neda Jabbari,Li Liu,Siobán B. Keel,Qiang Tian,Janis L. Abkowitz
View Articletitled, Single-cell analyses demonstrate that a heme–GATA1 feedback loop regulates red cell differentiation
Supplemental data
Human erythrocyte band 3 is a host receptor for Plasmodium falciparum glutamic acid–rich protein
Haifa Almukadi,Christopher Schwake,Maima M. Kaiser,D. C. Ghislaine Mayer,James Schiemer,Michael R. Baldwin,Shreeya Hegde,Yunzhe Lu,Toshihiko Hanada,Athar H. Chishti
View Articletitled, Human erythrocyte band 3 is a host receptor for <em>Plasmodium falciparum</em> glutamic acid–rich protein
Supplemental data

THROMBOSIS AND HEMOSTASIS

Neutrophil α-defensins promote thrombosis in vivo by altering fibrin formation, structure, and stability
Rami Abu-Fanne,Victoria Stepanova,Rustem I. Litvinov,Suhair Abdeen,Khalil Bdeir,Mohamed Higazi,Emad Maraga,Chandrasekaran Nagaswami,Alexander R. Mukhitov,John W. Weisel,Douglas B. Cines,Abd Al-Roof Higazi
View Articletitled, Neutrophil α-defensins promote thrombosis in vivo by altering fibrin formation, structure, and stability
Supplemental data

LETTERS TO BLOOD

Prognostic value of MRD in CLL patients with comorbidities receiving chlorambucil plus obinutuzumab or rituximab
Clinical Trials & Observations
Anton W. Langerak,Matthias Ritgen,Valentin Goede,Sandra Robrecht,Jasmin Bahlo,Kirsten Fischer,Michael Steurer,Marek Trněný,Stephen P. Mulligan,Ulrich J. M. Mey,Kerstin Trunzer,Günter Fingerle-Rowson,Kathryn Humphrey,Stephan Stilgenbauer,Sebastian Böttcher,Monika Brüggemann,Michael Hallek,Michael Kneba,Jacques J. M. van Dongen
View Articletitled, Prognostic value of MRD in CLL patients with comorbidities receiving chlorambucil plus obinutuzumab or rituximab
Supplemental data
Tenofovir vs lamivudine for the prevention of hepatitis B virus reactivation in advanced-stage DLBCL
Clinical Trials & Observations
Marco Picardi,Roberta Della Pepa,Claudia Giordano,Irene Zacheo,Novella Pugliese,Chiara Mortaruolo,Fabio Trastulli,Antonio Giordano,Mariano Lucignano,Maria Di Perna,Marta Raimondo,Claudia Salvatore,Fabrizio Pane
View Articletitled, Tenofovir vs lamivudine for the prevention of hepatitis B virus reactivation in advanced-stage DLBCL

BLOOD WORK

Unusual presentation of classic Hodgkin lymphoma
Kirill A. Lyapichev,M. James You
View Articletitled, Unusual presentation of classic Hodgkin lymphoma
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