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Journal Articles

Acute Myeloid Leukemia Export Mitochondria in Extracellular Vesicles Which Induces Pro-Tumoral Changes in Bone Marrow Macrophages

Jamie A Moore, BSc, MSc, Jayna J Mistry, BSc, Rebecca H Horton, Charlotte Hellmich, MBBChir, Adam Pattinson, MSc, BSc, Adam Morfakis, BSc, Yu Sun, BSc, MSc, PhD, Matthew Lawes, MD, Christopher J Morris, PhD, Anna Haestier, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1427.
https://doi.org/10.1182/blood-2019-128447
Published: 2019
Journal Articles

Superoxide Drives PI3 Kinase Mediated Mitochondria Transfer from the Bone Marrow Microenvironment to Hematopoietic Stem Cells in Response to Salmonella Typhimurium

Jayna J Mistry, BSc, Christopher R Marlein, PhD, Jamie A Moore, BSc, MSc, Charlotte Hellmich, MBBChir, Iain Macauley, PhD BSc, Naiara Beraza, PhD, Yu Sun, BSc, MSc, PhD, Adam Morfakis, BSc, Angela Patterson, PhD, Rebecca H Horton, Devina Divekar, Christopher J Morris, PhD, Anna Haestier, Bsc, PgD MBBS, MRCOG, Federica Di Palma, PhD, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2490.
https://doi.org/10.1182/blood-2019-128241
Published: 2019
Journal Articles

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment

Amina M. Abdul-Aziz, Yu Sun, Charlotte Hellmich, Christopher R. Marlein, Jayna Mistry, Eoghan Forde, Rachel E. Piddock, Manar S. Shafat, Adam Morfakis, Tarang Mehta, Federica Di Palma, Iain Macaulay, Christopher J. Ingham, Anna Haestier, Angela Collins, Judith Campisi, Kristian M. Bowles, Stuart A. Rushworth
Journal: Blood
Blood (2019) 133 (5): 446–456.
https://doi.org/10.1182/blood-2018-04-845420
Published: 2019
Includes: Supplemental data
Journal Articles

Stressed Hematopoiesis Induces Mitochondrial Trafficking to Hematopoietic Stem Cells

Jayna J Mistry, BSc, Christopher Richard Marlein, BSc, Iain Macauley, PhD BSc, Rebecca H Horton, Adam Morfakis, BSc, Charlotte Hellmich, MBBChir, BSc, MRCP, Anna Haestier, Bsc, PgD MBBS, MRCOG, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 3849.
https://doi.org/10.1182/blood-2018-99-110930
Published: 2018
Journal Articles

NOX2 Derived Superoxide Induces Pro-Tumoral p16INK4a Driven Senescence in the AML Bone Marrow Microenvironment

Charlotte Hellmich, MBBChir, BSc, MRCP, Amina Abdul-Aziz, MSc, Yu Sun, BSc, MSc, Christopher Richard Marlein, BSc, Eoghan Forde, Rachel E Piddock, BSc, Manar Shafat, MSc, Adam Morfakis, BSc, Mehta Tarang, Federica Di Palma, Christopher Ingham, Angela Collins, MBBS, Anna Haestier, Bsc, PgD MBBS, MRCOG, Judith Campisi, PhD, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 2770.
https://doi.org/10.1182/blood-2018-99-115274
Published: 2018